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Journal Articles

Hemoglobin S Polymerization Can be Inhibited By Alterations in Erythrocyte Glycolysis

William R. Simmons, Quan Li, PhD, John A. Hausman, Suilan Zheng, PhD, William Eaton, MD, Philip S. Low, PhD, David M. Bodine, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 977.
https://doi.org/10.1182/blood-2019-121709
Published: 2019
Journal Articles

Manipulating Metabolic Plasticity By Targeting Pyruvate Kinase M2 in Platelets Inhibits Arterial Thrombosis

Manasa Nayak, PhD, Nirav Dhanesha, PhD, Manish Jain, PhD, Anil Chauhan, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 868.
https://doi.org/10.1182/blood-2018-99-112704
Published: 2018
Journal Articles

Sumoylation of Pyruvate Kinase M2 Inhibits Myeloid Differentiation in Hematopoietic Cells

Li Xia, PhD, Xin-Ran Wang, MA, Ran Wei, BA, Jin-Song Yan, MD PhD, Guo-Qiang Chen, PhD, Ying Lu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3919.
https://doi.org/10.1182/blood-2018-99-117899
Published: 2018
Journal Articles

Population Pharmacokinetics and Pharmacodynamics of AG-519, a Pyruvate Kinase Activator for the Treatment of Pyruvate Kinase Deficiency, in Human Healthy Volunteers

Kha Le, Marvin Cohen, Ann J Barbier, Elizabeth Merica, Charles Kung, Penelope A Kosinski, Scott Biller, Hua Yang
Journal: Blood
Blood (2016) 128 (22): 1263.
https://doi.org/10.1182/blood.V128.22.1263.1263
Published: 2016
Journal Articles

Characterization of Metabolic Response to AG-348, an Allosteric Activator of Red Cell Pyruvate Kinase, in Healthy Volunteers and Pyruvate Kinase Deficiency Patients

Victor Chubukov, Kendall Johnson, Penelope A Kosinski, Michelle Clasquin, Abhishek Jha, Hyeryun Kim, Thomas P Roddy, Elizabeth Merica, Ann J Barbier, Lenny Dang, Lee Silverman, Charles Kung
Journal: Blood
Blood (2016) 128 (22): 2452.
https://doi.org/10.1182/blood.V128.22.2452.2452
Published: 2016
Journal Articles

Population Pharmacokinetics and Pharmacodynamics of AG-348 in Healthy Human Volunteers Guide Dose Selection for the Treatment of Pyruvate Kinase Deficiency

Kha Le, PhD, Marvin Cohen, Yue Chen, Hyeryun Kim, Bruce Silver, Sam Agresta, MD, Elizabeth Merica, Charles Kung, Penelope Kosinski, Lee Silverman, Scott Biller, Hua Yang, PhD
Journal: Blood
Blood (2015) 126 (23): 3336.
https://doi.org/10.1182/blood.V126.23.3336.3336
Published: 2015
Journal Articles

Metabolomic Profiling Identifies Mechanisms Regulating Hypoxia-Induced Drug Resistance In Multiple Myeloma

Patricia Maiso, PhD, Daisy Huynh, MPS, Yosra Aljawai, MS, John M. Asara, PhD, Antonio Sacco, BS, Michele Moschetta, MD, Yuji Mishima, PhD, Aldo M Roccaro, MD, PhD, Alec Kimmelman, MD, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2013) 122 (21): 121.
https://doi.org/10.1182/blood.V122.21.121.121
Published: 2013
Journal Articles

Cellular Bioenergetics in Lymphoid Neoplasia

Matthew Vander Heiden, MD, PhD
Journal: Blood
Blood (2011) 118 (21): SCI-25.
https://doi.org/10.1182/blood.V118.21.SCI-25.SCI-25
Published: 2011
Journal Articles

Ex Vivo Treatment of Erythroid Cells with Glycolytic Intermediates for Metabolic Correction of Pyruvate Kinase Deficiency.

Hitoshi Kanno, MD PhD, Ken-ichi Aisaki, MD PhD, Takako Hamada, Shin-ichi Okada, Hisaichi Fujii, MD PhD
Journal: Blood
Blood (2004) 104 (11): 3689.
https://doi.org/10.1182/blood.V104.11.3689.3689
Published: 2004
Journal Articles

Epinephrine induces platelet fibrinogen receptor expression, fibrinogen binding, and aggregation in whole blood in the absence of other excitatory agonists

SJ Shattil, A Budzynski, MC Scrutton
Journal: Blood
Blood (1989) 73 (1): 150–158.
https://doi.org/10.1182/blood.V73.1.150.150
Published: 1989