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Journal Articles

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

Free
Sarah Pagliaro, Pharm D, Christophe Desterke, Herve Acloque, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 934.
https://doi.org/10.1182/blood-2018-99-110679
Published: 2018
Journal Articles

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS)

Free
Leylah M. Drusbosky, PhD, Kimberly E. Hawkins, PhD BS, Cesia Salan, Madeleine Turcotte, MS, Glenda G. Anderson, Neeraj Kumar Singh, B.Tech, Saumya Radhakrishnan, BT, Yashaswini Ullal, BE, Anay Talawdekar, MT, Huzaifa Sikora, BT, Prashant Nair, BT, Priyanka Bhowmick, MS, Taher Abbasi, MS, MBA, Shireen Vali, PhD, Fei Zou, PhD, Nosha Farhadfar, MD, Hemant S. Murthy, MD, Biljana N. Horn, MD, Helen L. Leather, Paul Castillo, MD, Barry Sawicki, BS, Randy A. Brown, MD, Maxim Norkin, MD, John W. Hiemenz, MD, Jack W. Hsu, MD, William Slayton, MD, John R. Wingard, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4277.
https://doi.org/10.1182/blood.V130.Suppl_1.4277.4277
Published: 2017
Journal Articles

Icare 1: A Prospective Clinical Trial to Predict Treatment Response Based on Mutanome-Informed Computational Biology in Patients with AML and MDS

Free
Leylah Drusbosky, PhD, Elizabeth Wise, BS, Shireen Vali, PhD, Taher Abbasi, Ansu Kumar, Neeraj Kumar Singh, Kabya Basu, Chandan Kumar, Amjad Husain, Fei Zou, PhD, Caitlin Tucker, BS, Randy A Brown, MD, Maxim Norkin, MD PhD, John Hiemenz, MD, John R. Wingard, MD, Jack W Hsu, MD, Christopher R. Cogle, MD
Journal: Blood
Blood (2016) 128 (22): 594.
https://doi.org/10.1182/blood.V128.22.594.594
Published: 2016
Journal Articles

A Comparative Oncology Analysis of Canine T-Cell Lymphoma (TCL): Immunohistochemical Study and Next Generation Sequencing for Protein Analysis and Genomic Target Discovery

Free
Athena Kritharis, MD, J. Tyson McDonald, PhD, Afshin Beheshti, PhD, Monika Pilichowska, MD, Kristine Burgess, DVM, MS, Luisel Ricks-Santi, PhD, Elizabeth McNiel, DVM, PhD, Ravi Dashnamoorthy, PhD, Andrew M. Evens, DO, MSc
Journal: Blood
Blood (2015) 126 (23): 3883.
https://doi.org/10.1182/blood.V126.23.3883.3883
Published: 2015
Journal Articles

Use of 2HG Levels in the Serum, Urine, or Bone Marrow to Predict IDH Mutations in Adults with Acute Myeloid Leukemia

Free
Andrew M. Brunner, MD, Donna S Neuberg, ScD, Seth A. Wander, MD PhD, Hossein Sadrzadeh, MD, Karen K. Ballen, MD, Philip C. Amrein, MD, Gabriela S. Hobbs, MD, Yi-Bin Chen, MD, Ashley M. Perry, BS, Christelle Joseph, Meghan E. Burke, Aura Y Ramos, Regina Silver, Ilene Galinsky, ANP, Sophia Adamia, PhD, Darrell Borger, PhD, Anthony J Iafrate, MD PhD, Richard M. Stone, MD, Amir T. Fathi, MD
Journal: Blood
Blood (2015) 126 (23): 2597.
https://doi.org/10.1182/blood.V126.23.2597.2597
Published: 2015
Journal Articles

Common cancer-associated PIK3CA activating mutations rarely occur in Langerhans cell histiocytosis

Free
Sébastien Héritier, Raphael Saffroy, Nina Radosevic-Robin, Yolaine Pothin, Héléne Pacquement, Michel Peuchmaur, Antoinette Lemoine, Julien Haroche, Jean Donadieu, Jean-Francois Emile
Journal: Blood
Blood (2015) 125 (15): 2448–2449.
https://doi.org/10.1182/blood-2015-01-625491
Published: 2015
Includes: Supplemental data
Journal Articles

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease

Free
Brief Report
Jean-François Emile, Eli L. Diamond, Zofia Hélias-Rodzewicz, Fleur Cohen-Aubart, Frédéric Charlotte, David M. Hyman, Eunhee Kim, Raajit Rampal, Minal Patel, Chezi Ganzel, Shlomzion Aumann, Gladwys Faucher, Catherine Le Gall, Karen Leroy, Magali Colombat, Jean-Emmanuel Kahn, Salim Trad, Philippe Nizard, Jean Donadieu, Valérie Taly, Zahir Amoura, Omar Abdel-Wahab, Julien Haroche
Journal: Blood
Blood (2014) 124 (19): 3016–3019.
https://doi.org/10.1182/blood-2014-04-570937
Published: 2014
Includes: Supplemental data
Journal Articles

The Impact Of Subclonal Versus Clonal Novel Recurrent Mutations On Treatment Outcome In Previously Untreated High Risk CLL Patients: Results From The HOVON68 Trial

Free
Doreen te Raa, MD, Arnon P. Kater, MD PhD, Wendim Ghidey Alemayehu, Alexander Jethwa, Jennifer Hullein, Eric Eldering, PhD, Tatjana Stankovic, MD, PhD, Thorsten Zenz, MD, Christian H Geisler, Marinus H.J. Van Oers, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2861.
https://doi.org/10.1182/blood.V122.21.2861.2861
Published: 2013
Journal Articles

P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse

Free
Sunil Iyengar, Andrew Clear, Csaba Bödör, Lenushka Maharaj, Abigail Lee, Maria Calaminici, Janet Matthews, Sameena Iqbal, Rebecca Auer, John Gribben, Simon Joel
Journal: Blood
Blood (2013) 121 (12): 2274–2284.
https://doi.org/10.1182/blood-2012-10-460832
Published: 2013
Journal Articles

High Resolution Genomic Analysis In CLL Demonstrates Genomic Stability In Untreated Patients and Novel Markers of Progression In Treated Patients

Free
Jennifer R Brown, MD, PhD, Megan Hanna, Bethany Tesar, Lillian Werner, Hazel Reynolds, Stacey M Fernandes, Laura Macconaill, Yaoyu Wang, Mick Correll, Donna Neuberg, ScD, Arnold S. Freedman, MD
Journal: Blood
Blood (2010) 116 (21): 2426.
https://doi.org/10.1182/blood.V116.21.2426.2426
Published: 2010
Journal Articles

SHIP1 and PTEN Co-Inactivation and Akt Pathway Targeting in ALL.

Free
Mitchell B. Diccianni, PhD, BSc, Lisa M. Barnhill, BS, Tony Lo, BS, MS, Alice L. Yu, PhD
Journal: Blood
Blood (2009) 114 (22): 2386.
https://doi.org/10.1182/blood.V114.22.2386.2386
Published: 2009
Journal Articles

Mutations in the Catalytic Subunit of Class IA PI3K Are Leukemogenic In Vivo.

Free
Stefan Horn, James A. McCubrey, Carol Stocking, Lorenz Trumper, Jorg Basecke
Journal: Blood
Blood (2007) 110 (11): 875.
https://doi.org/10.1182/blood.V110.11.875.875
Published: 2007
Journal Articles

Frequent Mutation of the PIK3CA Gene in Saudi Arabian Diffuse Large B-Cell Lymphoma.

Free
Jehad A. Abubaker, PhD, Prashant P. Bavi, MD, Sayer Al-Harbi, MSc, Valerie L. Atizado, Bsc, Fouad Al-Dayel, MD, Adnan Ezzat, MD, Shahab Uddin, PhD, Khawla S. Al-Kuraya, MD, FCAP
Journal: Blood
Blood (2006) 108 (11): 4308.
https://doi.org/10.1182/blood.V108.11.4308.4308
Published: 2006
Journal Articles

Mutations of the Catalytic Subunit of Class IA PI3K Are Constitutively Active and Confer Factor-Independent Growth to Early Hematopoietic Cells.

Free
Stefan Horn, James McCubrey, Carol Stocking, Lorenz Truemper, Jorg Basecke
Journal: Blood
Blood (2006) 108 (11): 1455.
https://doi.org/10.1182/blood.V108.11.1455.1455
Published: 2006
Journal Articles

Rare Mutations of the PIK3CA Gene in Hematologic Malignancies.

Free
Claudia I. Muller, M.D., Carl W. Miller, Ph.D., Wolf-K. Hofmann, M.D., Norihiko Kawamata, M.D., Ph.D., H. Phillip Koeffler, M.D.
Journal: Blood
Blood (2004) 104 (11): 4350.
https://doi.org/10.1182/blood.V104.11.4350.4350
Published: 2004
Journal Articles

Mutations of Oncogenes Involved in Signal Transduction Pathways Are Common in AML.

Free
Michael C. Heinrich, M.D., Andrea Haley, Patina Harell, Ajia Town, Troy Bainbridge, Marcus Schittenhelm, M.D., Laura McGreevey, Rita Braziel, M.D.
Journal: Blood
Blood (2004) 104 (11): 2575.
https://doi.org/10.1182/blood.V104.11.2575.2575
Published: 2004