Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 28

Sort by

Sort Order Select

Journal Articles

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

Jun Zhu, MD PhD, Grzegorz Nowakowski, MD, Qingyuan Zhang, Joshua Brody, MD, Xiuhua Sun, MD, Joseph Maly, MD, Yuqin Song, MD PhD, Yongping Song, MD PhD, Jennifer Kimberly Lue, MD, Wen Luo, PhD, Lei Zhang, MD, Isabel Han, Manoj Jivani, Young Liu, Ling Li, MD, Joan Sun, MBA, Stephen D. Smith, MD

Blood (2019) 134 (Supplement_1): 5330.

https://doi.org/10.1182/blood-2019-124930

Published: 2019

Journal Articles

Role of Mutant p53 in the Progression of Chronic Lymphocytic Leukemia

Janani Ravikrishnan, Tzung-Huei Lai, PhD DVM, Elizabeth Muhowski, Lindsey Brinton, PhD, Katie Williams, MS, Alexandria Thompson, James S. Blachly, MD, Hatice Gulcin Ozer, PhD, John C. Byrd, MD, Rosa Lapalombella, PhD, Jennifer Woyach, MD, Deepa Sampath, PhD

Blood (2019) 134 (Supplement_1): 2526.

https://doi.org/10.1182/blood-2019-128574

Published: 2019

Journal Articles

Eosinophil Differentiation and Viability in Hypereosinophilia Is Impaired By Genetic and Pharmacologic Targeting of LCP1 and PKC Beta

Guangxin Ma, Deniz Gezer, MD, Oliver Herrmann, Msc, Andreas Reiter, MD, Mohamad Jawhar, Mirle Schemionek, Tim H. Brümmendorf, MD, Steffen Koschmieder, MD, Nicolas Chatain, PhD

Blood (2018) 132 (Supplement 1): 4320.

https://doi.org/10.1182/blood-2018-99-114646

Published: 2018

Journal Articles

A Virtual B Cell Lymphoma Model to Predict Effective Combination Therapy

Wei Du, BA, Rebecca Goldstein, BA, Yanwen Jiang, PhD, Omar Aly, BA, Leandro Cerchietti, MD, Ari M. Melnick, MD, Olivier Elemento, PhD

Blood (2014) 124 (21): 928.

https://doi.org/10.1182/blood.V124.21.928.928

Published: 2014

Journal Articles

Thrombin Induces Specific Signaling Pathways Distinct From Simultaneous Stimulation With PAR1 and PAR4 Agonist Peptides In Human Platelets

Amal Arachiche, PhD, Marvin T. Nieman, PhD

Blood (2013) 122 (21): 3516.

https://doi.org/10.1182/blood.V122.21.3516.3516

Published: 2013

Journal Articles

Enzastaurin Induces Apoptosis and Cell Cycle Arrest in B-Cell Acute Lymphoblastic Leukemia Cell Lines Through AKT Pathway Inhibition and ß-Catenin Accumulation

Nakhle Saba, MD, Magdalena Angelova, PhD, Patricia Lobelle-Rich, Laura S Levy, PhD

Blood (2012) 120 (21): 1350.

https://doi.org/10.1182/blood.V120.21.1350.1350

Published: 2012

Journal Articles

Chemo-Resistance in Diffuse Large Cell Lymphoma: Novel Drug Combinations Targeting NFAT/NF-Kb Growth/Survival/Chemo-Resistance Signaling Pathways in Validated Novel Experimental Systems

Lan V Pham, PhD, Archito T. Tamayo, MS, Changping Li, MD, John Lee, MD, Luis Fayad, MD, Richard J. Ford, MD, PhD

Blood (2011) 118 (21): 1428.

https://doi.org/10.1182/blood.V118.21.1428.1428

Published: 2011

Journal Articles

Prox1 Suppressed Tumor Cell Growth by the Down Regulation of PKCβII Through the DNA Methylation

Kazumi Hagiwara, Takashi Murate, MD, Yasuhiko Miyata, MD, PhD, Tomomitsu Hotta, MD, PhD, Hirokazu Nagai, MD, PhD

Blood (2011) 118 (21): 5227.

https://doi.org/10.1182/blood.V118.21.5227.5227

Published: 2011

Journal Articles

Rewiring of the Protein Kinase C Beta 2 (PKC βII) and Bcr/Abl Signal Transduction Pathways

David Arthur Hoekstra, II, Louise M Carlson, Kelvin P Lee, MD

Blood (2011) 118 (21): 1673.

https://doi.org/10.1182/blood.V118.21.1673.1673

Published: 2011

Journal Articles

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Malte Rieken, Alessandro Pastore, Elena Hartmann, Andreas Rosenwald, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD

Blood (2010) 116 (21): 2893.

https://doi.org/10.1182/blood.V116.21.2893.2893

Published: 2010

Journal Articles

Characterisation of B Cell Receptor-Induced NF-KB Activation In Chronic Lymphocytic Leukaemia Cells

Fatima Talab, Victoria Thompson, John C Allen, Ke Lin, Joseph R Slupsky

Blood (2010) 116 (21): 375.

https://doi.org/10.1182/blood.V116.21.375.375

Published: 2010

Journal Articles

RNA-Expression and Proteome Analysis Identify Complementary but Not Identical Molecular Targets in Enzastaurin-Treated Mantle Cell Lymphoma.

Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Elena Hartmann, MD, Andreas Rosenwald, Wolfgang Hiddemann, Martin H. Dreyling

Blood (2009) 114 (22): 1915.

https://doi.org/10.1182/blood.V114.22.1915.1915

Published: 2009

Journal Articles

Association of Gene-Gene Interactions with Venous Thromboembolism (VTE): A Pathway-Directed Candidate-Gene Case-Control Study.

John A. Heit, M.D., Sebastian M. Armasu, M.S., Tanya M. Petterson, M.S., David N. Rider, Julie M. Cunningham, Ph.D., Mariza de Andrade, Ph.D.

Blood (2009) 114 (22): 150.

https://doi.org/10.1182/blood.V114.22.150.150

Published: 2009

Journal Articles

Synergistic Antilymphoma Effect of Protein Kinase C Beta (PKCβ) and mTOR Inhibition in Mantle Cell Lymphoma.

Grit Hutter, Yvonne Zimmermann, Malte Rieken, Elena Hartmann, MD, Vindi Jurinovic, Andreas Rosenwald, Marc Weinkauf, Wolfgang Hiddemann, Martin H. Dreyling

Blood (2009) 114 (22): 4780.

https://doi.org/10.1182/blood.V114.22.4780.4780

Published: 2009

Journal Articles

Recruitment of PKC-Beta to Lipid Rafts Mediates Apoptosis-Resistance in Chronic Lymphocytic Leukemia Expressing Zap-70.

Ingo Ringshausen, Michaela Wagner, Gloria Lutzny, Madlen Oelsner, Yvonne Feuerstacke, Thomas Decker, Christian Bogner, Christian Peschel, MD, Christian Meyer zum Buschenfelde

Blood (2009) 114 (22): 2354.

https://doi.org/10.1182/blood.V114.22.2354.2354

Published: 2009

Journal Articles

PKCβ Is Essential for the Development of CLL in the TCL1 Transgenic Mouse Model: Validation of PKCβ as a Therapeutic Target in CLL

Alexander Egle, MD, Claudia Holler, Josefina D. Pinon, Ursula Denk, Christoph Heyder, Richard Greil

Blood (2008) 112 (11): 4164.

https://doi.org/10.1182/blood.V112.11.4164.4164

Published: 2008

Journal Articles

Effects of Enzastaurin, Alone or in Combination, on Signalling Pathway Controlling Growth and Survival of B-Cell Lymphoma Cell Lines

Stefano Sacchi, Monica Civallero, Maria Cosenza, Giulia Grisendi, Luigi Marcheselli, Antonino Neri, MD

Blood (2008) 112 (11): 4978.

https://doi.org/10.1182/blood.V112.11.4978.4978

Published: 2008

Journal Articles

Proteomic Analysis of Pkc-Beta Inhibitor Enzastaurin-Treated Mantle Cell Lymphoma

Marc Weinkauf, Malte Rieken, Alessandro Pastore, Wolfgang Hiddemann, Martin H. Dreyling, MD

Blood (2008) 112 (11): 4982.

https://doi.org/10.1182/blood.V112.11.4982.4982

Published: 2008

Journal Articles

Inhibition of Human Lymphoma Cell Growth by the PKC-Beta Selective Inhibitor Enzastaurin (LY317615) in Combination with Multiple Therapeutic Agents.

Randall M Rossi, Marlene Balys, Dean Franklin, Valerie Grose, Richard I Fisher, Craig Jordan

Blood (2008) 112 (11): 1595.

https://doi.org/10.1182/blood.V112.11.1595.1595

Published: 2008

Journal Articles

The Functional Impact of PKCβ/PI3K/AKT Signalling on Translational Initiation in MCL

Grit Hutter, Yvonne Zimmermann, Marc Weinkauf, Alina Postnikova, Tobias Weiglein, Wolfgang Hiddemann, Martin Dreyling

Blood (2008) 112 (11): 2624.

https://doi.org/10.1182/blood.V112.11.2624.2624

Published: 2008

NARROW

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

Role of Mutant p53 in the Progression of Chronic Lymphocytic Leukemia

Eosinophil Differentiation and Viability in Hypereosinophilia Is Impaired By Genetic and Pharmacologic Targeting of LCP1 and PKC Beta

A Virtual B Cell Lymphoma Model to Predict Effective Combination Therapy

Thrombin Induces Specific Signaling Pathways Distinct From Simultaneous Stimulation With PAR1 and PAR4 Agonist Peptides In Human Platelets

Enzastaurin Induces Apoptosis and Cell Cycle Arrest in B-Cell Acute Lymphoblastic Leukemia Cell Lines Through AKT Pathway Inhibition and ß-Catenin Accumulation

Chemo-Resistance in Diffuse Large Cell Lymphoma: Novel Drug Combinations Targeting NFAT/NF-Kb Growth/Survival/Chemo-Resistance Signaling Pathways in Validated Novel Experimental Systems

Prox1 Suppressed Tumor Cell Growth by the Down Regulation of PKCβII Through the DNA Methylation

Rewiring of the Protein Kinase C Beta 2 (PKC βII) and Bcr/Abl Signal Transduction Pathways

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

Characterisation of B Cell Receptor-Induced NF-KB Activation In Chronic Lymphocytic Leukaemia Cells

RNA-Expression and Proteome Analysis Identify Complementary but Not Identical Molecular Targets in Enzastaurin-Treated Mantle Cell Lymphoma.

Association of Gene-Gene Interactions with Venous Thromboembolism (VTE): A Pathway-Directed Candidate-Gene Case-Control Study.

Synergistic Antilymphoma Effect of Protein Kinase C Beta (PKCβ) and mTOR Inhibition in Mantle Cell Lymphoma.

Recruitment of PKC-Beta to Lipid Rafts Mediates Apoptosis-Resistance in Chronic Lymphocytic Leukemia Expressing Zap-70.

PKCβ Is Essential for the Development of CLL in the TCL1 Transgenic Mouse Model: Validation of PKCβ as a Therapeutic Target in CLL

Effects of Enzastaurin, Alone or in Combination, on Signalling Pathway Controlling Growth and Survival of B-Cell Lymphoma Cell Lines

Proteomic Analysis of Pkc-Beta Inhibitor Enzastaurin-Treated Mantle Cell Lymphoma

Inhibition of Human Lymphoma Cell Growth by the PKC-Beta Selective Inhibitor Enzastaurin (LY317615) in Combination with Multiple Therapeutic Agents.

The Functional Impact of PKCβ/PI3K/AKT Signalling on Translational Initiation in MCL

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only