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Journal Articles

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Cameron McDonald-Hyman, BA, Govindarajan Thangavelu, PhD, James Muller, Guoan Zhang, PhD, Sudha Kumari, PhD, Asim Saha, PhD, Brent H. Koehn, PhD, Jason S. Mitchell, PhD, Brian T Fife, PhD, Jonathan S. Serody, MD, Mark J. Osborn, PhD, Keli L. Hippen, PhD, Ameeta Kelekar, PhD, David H. Munn, MD, Amnon Altman, PhD, Thomas A. Neubert, PhD, Michael L. Dustin, PhD, Bruce R. Blazar, MD
Journal: Blood
Blood (2015) 126 (23): 849.
https://doi.org/10.1182/blood.V126.23.849.849
Published: 2015
Journal Articles

Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1

Le Xuan Truong Nguyen, Yunqin Lee, Lenore Urbani, Paul J. Utz, Anne W. Hamburger, John B. Sunwoo, Beverly S. Mitchell
Journal: Blood
Blood (2015) 125 (16): 2519–2529.
https://doi.org/10.1182/blood-2014-12-616433
Published: 2015
Includes: Supplemental data
Journal Articles

A Virtual B Cell Lymphoma Model to Predict Effective Combination Therapy

Wei Du, BA, Rebecca Goldstein, BA, Yanwen Jiang, PhD, Omar Aly, BA, Leandro Cerchietti, MD, Ari M. Melnick, MD, Olivier Elemento, PhD
Journal: Blood
Blood (2014) 124 (21): 928.
https://doi.org/10.1182/blood.V124.21.928.928
Published: 2014
Journal Articles

Activated B-Cell DLBCL with Downstream Activation of Survival Signaling Requires PIM Kinase Activity to Maintain Oncoprotein Translation

Tara L. Peters, BA, Ana A Tula-Sanchez, PhD, Lingxiao Li, PhD, Praechompoo Pongtornpipat, BS, Mengdie WANG, BS, Nicolette BROWN, BS, Soham D. Puvvada, MD, Jonathan H. Schatz, MD
Journal: Blood
Blood (2014) 124 (21): 4496.
https://doi.org/10.1182/blood.V124.21.4496.4496
Published: 2014
Journal Articles

PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL

Dalia El-Gamal, Katie Williams, Taylor D. LaFollette, Matthew Cannon, James S. Blachly, Yiming Zhong, Jennifer A. Woyach, Erich Williams, Farrukh T. Awan, Jeffrey Jones, Leslie Andritsos, Kami Maddocks, Chia-Hsien Wu, Ching-Shih Chen, Amy Lehman, Xiaoli Zhang, Rosa Lapalombella, John C. Byrd
Journal: Blood
Blood (2014) 124 (9): 1481–1491.
https://doi.org/10.1182/blood-2014-05-574830
Published: 2014
Includes: Supplemental data
Journal Articles

PKC Inhibitor AEB071 Demonstrates Pre-Clinical Activity In Chronic Lymphocytic Leukemia

Dalia ElGamal, PhD, Yiming Zhong, PhD, Katie Williams, MS, Chia-Hsien Wu, Ching-Shih Chen, PhD, Rosa Lapalombella, PhD, John C. Byrd, MD
Journal: Blood
Blood (2013) 122 (21): 4187.
https://doi.org/10.1182/blood.V122.21.4187.4187
Published: 2013
Journal Articles

Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT

Roberto Negro, Stefania Gobessi, Pablo G. Longo, Yantao He, Zhong-Yin Zhang, Luca Laurenti, Dimitar G. Efremov
Journal: Blood
Blood (2012) 119 (26): 6278–6287.
https://doi.org/10.1182/blood-2012-01-403162
Published: 2012
Includes: Supplemental data