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Journal Articles

Defibrotide Inhibits Endothelial Cell Injury Induced By Plasmas of Patients with Thrombotic Microangiopathies

Jeffrey Laurence, MD, Sonia Elhadad, PhD

Blood (2019) 134 (Supplement_1): 3676.

https://doi.org/10.1182/blood-2019-124158

Published: 2019

Journal Articles

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Charu Mehta, MS, Isabela J Fraga de Andrade, Bachelors in Biological Science, Nobuyuki Tanimura, PhD, Gary M Wilson, Erik A. Ranheim, MD PhD, Joshua J Coon, PhD, Emery H Bresnick, PhD

Blood (2019) 134 (Supplement_1): 155.

https://doi.org/10.1182/blood-2019-126917

Published: 2019

Journal Articles

Staurosporine Induces Caspase-Dependent Proteolysis of MEF2D-Fusion Protein and Cell Death Selective to MEF2D-Fusion-Positive ALL Cells

Naoyuki Tange, MD, Fumihiko Hayakawa, MD, PhD, Takahiko Yasuda, MD, PhD, Hideyuki Yamamoto, MD, Daiki Hirano, MD, PhD, Shinobu Tsuzuki, MD,PhD, Hitoshi Kiyoi, MD PhD

Blood (2019) 134 (Supplement_1): 1349.

https://doi.org/10.1182/blood-2019-123602

Published: 2019

Journal Articles

Combinatorial Approaches to Overcome Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors

David J Young, MD PhD, Jun O Liu, PhD, Donald Small, MD PhD

Blood (2018) 132 (Supplement 1): 1362.

https://doi.org/10.1182/blood-2018-99-118820

Published: 2018

Journal Articles

A Novel Method for Overcoming Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors

David J Young, MD PhD, Donald Small, MD PhD

Blood (2017) 130 (Supplement 1): 1241.

https://doi.org/10.1182/blood.V130.Suppl_1.1241.1241

Published: 2017

Journal Articles

Biochemical Characterization of GS-4059 As a Potent and Selective Covalent Irreversible Inhibitor of Bruton's Tyrosine Kinase

Albert Liclican, Weimei Xing, Loredana Serafini, Ting Wang, Kathy Brendza, Justin Lutz, Adrian S. Ray, Brian Schultz, Roman Sakowicz, Joy Y. Feng

Blood (2016) 128 (22): 1594.

https://doi.org/10.1182/blood.V128.22.1594.1594

Published: 2016

Journal Articles

The Impact of Chemotherapeutic Agents on Signaling and Epigenetics in Vascular Endothelial Cells

Srila Gopal, MD, Amanda Creech, Adam Officer, Shawn Egri, Desiree Davison, Jacob D Jaffe, PhD, Iris Z Jaffe, MD PhD

Blood (2016) 128 (22): 1353.

https://doi.org/10.1182/blood.V128.22.1353.1353

Published: 2016

Journal Articles

Precision Medicine Assays Detect Novel Targetable FLT3 Fusions Amenable to Therapeutic Intervention in a Patient with Refractory Acute Myeloid Leukemia

Bradley A Patay, MD, Andrew Carson, PhD, Timothy J Martins, PhD, Sylvia Chien, Mary-Elizabeth M. Percival, MD MS, Taylor Sekizaki, Cody Hammer, Pamela S. Becker, MD PhD

Blood (2016) 128 (22): 5170.

https://doi.org/10.1182/blood.V128.22.5170.5170

Published: 2016

Journal Articles

A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury

Karen E.P. De Ceunynck, PhD, Christian G. Peters, PhD, Sharjeel A. Chaudhry, B.S., Abhishek Jain, PhD, Sarah J. Higgins, PhD, Omozuanvbo Aisiku, PhD, Jennifer Fitch-Tewfik, PhD, Christopher Dockendorff, PhD, Samir Parikh, MD PhD, Donald E. Ingber, PhD, Robert C. Flaumenhaft, MD PhD

Blood (2016) 128 (22): 3835.

https://doi.org/10.1182/blood.V128.22.3835.3835

Published: 2016

Journal Articles

Role of LIM Kinase in Oncogenic Signaling from FLT3 and KIT Receptors and Its Targeting in Myeloid Leukemia

Ruchi Pandey, PhD, Raghuveer Mali, PhD, Anindya Chatterjee, MS,PhD, Fabrice Paublant, Renaud Prudent, Laurence Lafanechere, Reuben Kapur, PhD

Blood (2015) 126 (23): 1257.

https://doi.org/10.1182/blood.V126.23.1257.1257

Published: 2015

Journal Articles

Activating Mutation of STAT3 Protects Lymphocytes from Apoptosis and Leads to a Clinical Phenotype Resembling the Autoimmune Lymphoproliferative Syndrome

Schafiq Nabhani, PhD, Hagit Miskin, MD, Cyrill Schipp, MSc, Dan Harlev, Shoshana Revel-Vilk, MD MSc, Michael Gombert, PhD, Sebastian Ginzel, MSc, Arndt Borkhardt, MD, Polina Stepensky, MD, Ute Fischer, PhD

Blood (2015) 126 (23): 2218.

https://doi.org/10.1182/blood.V126.23.2218.2218

Published: 2015

Journal Articles

Crispr Sgrnas Genome-Wide Screen Identifies the Proteasome Regulatory Subunit PSMC6 As a Bortezomib Resistance Gene in Human Multiple Myeloma Cells

Chang-Xin Shi, PhD, Klaus M Kortum, MD, Yuan Xiao Zhu, PhD, Patrick Jedlowski, Esteban Braggio, PhD, Laura Ann Bruins, Patrick G. Votruba, M.S., Moulun Luo, PhD, Robert A. Stewart, Jonathan M. Ahmann, A. Keith Stewart

Blood (2015) 126 (23): 450.

https://doi.org/10.1182/blood.V126.23.450.450

Published: 2015

Journal Articles

Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency

Blood (2015) 125 (5): 753–761.

https://doi.org/10.1182/blood-2014-08-593202

Published: 2015

Includes: Supplemental data

Journal Articles

STAT1 Gain-of-Function in Patients with Chronic Mucocutaneous Candidiasis Can be Detected By the Excessive Phosphorylation of STAT1 in Peripheral Blood Monocytes

Yoko Mizoguchi, MD PhD, Miyuki Tsumura, PhD, Satoshi Okada, MD PhD, Osamu Hirata, MD PhD, Shizuko Minegishi, Nobuyuki Hyakuna, MD PhD, Jean-Laurent Casanova, MD PhD, Tomohiro Morio, MD PhD, Masao Kobayashi, MD PhD

Blood (2014) 124 (21): 4111.

https://doi.org/10.1182/blood.V124.21.4111.4111

Published: 2014

Journal Articles

Low-Dose IL-2 Induces Bcl2 Expression and Resistance To Apoptosis In CD4 Regulatory T Cells

Kazuyuki Murase, MD, PhD, Yutaka Kawano, MD, PhD, Jeremy Ryan, SM, Ken-ichi Matsuoka, MD, PhD, Gregory Bascug, BS, Sean McDonough, MS, Robert W Smith, BS, Kristen Cowens, Suzan Lazo-Kallanian, John Daley, PhD, John Koreth, MBBS, DPhil, Robert J. Soiffer, MD, Anthony Letai, MD, PhD, Jerome Ritz, MD

Blood (2013) 122 (21): 3475.

https://doi.org/10.1182/blood.V122.21.3475.3475

Published: 2013

Journal Articles

Go6976, a Potent FLT3 Kinase Inhibitor, Exerts Antiproliferative Activity Against Acute Myeloid Leukemia Via Inhibition Of Survivin and Mcl-1 In The Presence Of Human Serum

Akira Yoshida, MD, PhD, Kouichi Zokumasu, Takanori Ueda, MD, PhD

Blood (2013) 122 (21): 3839.

https://doi.org/10.1182/blood.V122.21.3839.3839

Published: 2013

Journal Articles

TTT-3002 Is Active Against Relapsed/Refractory AML Patient Bone Marrow With FLT3 TKI-Resistance Mutations At Residue D835

Hayley S Ma, Ph.D., Bao Nguyen, M.S., Mark Levis, MD, PhD, Allen B Williams, PhD, Donald Small, MD, PhD

Blood (2013) 122 (21): 3818.

https://doi.org/10.1182/blood.V122.21.3818.3818

Published: 2013

Journal Articles

Deficiency Of JAGN1 Causes Severe Congenital Neutropenia Associated With Defective Secretory Pathway and Aberrant Myeloid Cell Homeostasis

Blood (2013) 122 (21): 439.

https://doi.org/10.1182/blood.V122.21.439.439

Published: 2013

Journal Articles

Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells

Omozuanvbo R. Aisiku, PhD, Christian G. Peters, PhD, Suzanne Gunnink, MD, James R. Dilks, Chris Dockendorff, Robert Flaumenhaft, M.D. Ph.D

Blood (2013) 122 (21): 23.

https://doi.org/10.1182/blood.V122.21.23.23

Published: 2013

Journal Articles

Collaboration Between MiR-125b, MiR-100 and MiR-99a Induces Vincristine Resistance in Childhood TEL-AML1 -Positive Acute Lymphoblastic Leukemia

Farhad Akbari Moqadam, Ellen Lange-Turenhout, Rob Pieters, MD, PhD, Monique L. Den Boer, PhD

Blood (2012) 120 (21): 1475.

https://doi.org/10.1182/blood.V120.21.1475.1475

Published: 2012

NARROW

Defibrotide Inhibits Endothelial Cell Injury Induced By Plasmas of Patients with Thrombotic Microangiopathies

Elucidating an Erythroblast Survival Mechanism: Differential Contributions of Exosome Complex Catalytic Subunits

Staurosporine Induces Caspase-Dependent Proteolysis of MEF2D-Fusion Protein and Cell Death Selective to MEF2D-Fusion-Positive ALL Cells

Combinatorial Approaches to Overcome Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors

A Novel Method for Overcoming Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors

Biochemical Characterization of GS-4059 As a Potent and Selective Covalent Irreversible Inhibitor of Bruton's Tyrosine Kinase

The Impact of Chemotherapeutic Agents on Signaling and Epigenetics in Vascular Endothelial Cells

Precision Medicine Assays Detect Novel Targetable FLT3 Fusions Amenable to Therapeutic Intervention in a Patient with Refractory Acute Myeloid Leukemia

A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury

Role of LIM Kinase in Oncogenic Signaling from FLT3 and KIT Receptors and Its Targeting in Myeloid Leukemia

Activating Mutation of STAT3 Protects Lymphocytes from Apoptosis and Leads to a Clinical Phenotype Resembling the Autoimmune Lymphoproliferative Syndrome

Crispr Sgrnas Genome-Wide Screen Identifies the Proteasome Regulatory Subunit PSMC6 As a Bortezomib Resistance Gene in Human Multiple Myeloma Cells

Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency

STAT1 Gain-of-Function in Patients with Chronic Mucocutaneous Candidiasis Can be Detected By the Excessive Phosphorylation of STAT1 in Peripheral Blood Monocytes

Low-Dose IL-2 Induces Bcl2 Expression and Resistance To Apoptosis In CD4 Regulatory T Cells

Go6976, a Potent FLT3 Kinase Inhibitor, Exerts Antiproliferative Activity Against Acute Myeloid Leukemia Via Inhibition Of Survivin and Mcl-1 In The Presence Of Human Serum

TTT-3002 Is Active Against Relapsed/Refractory AML Patient Bone Marrow With FLT3 TKI-Resistance Mutations At Residue D835

Deficiency Of JAGN1 Causes Severe Congenital Neutropenia Associated With Defective Secretory Pathway and Aberrant Myeloid Cell Homeostasis

Effects Of Biased PAR1 Ligands On Platelets and Endothelial Cells

Collaboration Between MiR-125b, MiR-100 and MiR-99a Induces Vincristine Resistance in Childhood TEL-AML1 -Positive Acute Lymphoblastic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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