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Journal Articles

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

Andrew Dunbar, Kelly L. Bolton, Sean M. Devlin, Francisco Sanchez-Vega, Jianjiong Gao, Jodi V. Mones, Jonathan Wills, Daniel Kelly, Mirko Farina, Keith B. Cordner, Young Park, Sirish Kishore, Krishna Juluru, Neil M. Iyengar, Ross L. Levine, Ahmet Zehir, Wungki Park, Alok A. Khorana, Gerald A. Soff, Simon Mantha
Journal: Blood
Blood (2021) 137 (15): 2103–2113.
https://doi.org/10.1182/blood.2020007488
Published: 2021
Includes: Supplemental data
Journal Articles

Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia

Lai N Chan, PhD, Daniel Braas, Christian Hurtz, PhD, Seyedmehdi Shojaee, PhD, Behzad Kharabi Masouleh, MD, Huimin Geng, PhD, Thomas Ernst, MD, Andreas Hochhaus, MD, Thomas Graeber, PhD, Markus Muschen, MDPhD
Journal: Blood
Blood (2014) 124 (21): 783.
https://doi.org/10.1182/blood.V124.21.783.783
Published: 2014
Journal Articles

Lineage-Specific Functions of LKB1 in CML and B Lymphoid Blast Crisis

Lai N Chan, PhD, Huimin Geng, PhD, Markus Muschen, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 34.
https://doi.org/10.1182/blood.V120.21.34.34
Published: 2012
Journal Articles

The Mir-17∼92 Cluster Activates mTORC1 Signaling in MCL by Targeting Multiple Regulators of the LKB1/AMPK/mTOR Pathway

Chengfeng Bi, MD, Chunsun Jiang, PhD, Xiaoxing Jiang, MD, Xin Huang, PhD, Mario R Fernandez, PhD, Javeed Iqbal, M. Sc, PhD, Robert E Lewis, PhD, Wing Chung Chan, MD, Timothy McKeithan, MD/PhD, Kai Fu, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 5118.
https://doi.org/10.1182/blood.V120.21.5118.5118
Published: 2012
Journal Articles

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

Alexa S. Green, Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer, Valerie Bardet, Sophie Park, Marc Foretz, Benoit Viollet, Norbert Ifrah, François Dreyfus, Olivier Hermine, Ivan Cruz Moura, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, Jerome Tamburini
Journal: Blood
Blood (2010) 116 (20): 4262–4273.
https://doi.org/10.1182/blood-2010-02-269837
Published: 2010
Includes: Supplemental data
Journal Articles

AMPK α2 subunit is involved in platelet signaling, clot retraction, and thrombus stability

Voahanginirina Randriamboavonjy, Johann Isaak, Timo Frömel, Benoit Viollet, Beate Fisslthaler, Klaus T. Preissner, Ingrid Fleming
Journal: Blood
Blood (2010) 116 (12): 2134–2140.
https://doi.org/10.1182/blood-2010-04-279612
Published: 2010
Includes: Multimedia, Supplemental data