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Issue Archive

Volume 2, Issue 1
February 19 2025
Issue Cover

Table of Contents

SYSTEMATIC REVIEW

Safety landscape of bispecific antibody therapy in non-Hodgkin lymphoma: a meta-analysis
Rodrigo Fonseca,Alex J. Liu,Blake T. Langlais,Diana Almader-Douglas,Holenarasipur R. Vikram,Talal Hilal
View Articletitled, Safety landscape of bispecific antibody therapy in non-Hodgkin lymphoma: a meta-analysis
Supplemental data

BASIC MECHANISMS OF NEOPLASIA

Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia
Olivia M. Depies,Qianqian Guo,Yuan Gao,Sutapa Sinha,Zhenqing Ye,Weiguo Han,Kari G. Rabe,Mingma S. Hoel,Heather C. Darby,Chuanhe Yu,Esteban Braggio,Sameer A. Parikh,Susan L. Slager,Neil E. Kay,Zhiquan Wang
View Articletitled, Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

JAK1/2 inhibitor ruxolitinib for the treatment of systemic chronic active Epstein-Barr virus disease: a phase 2 study
Clinical Trials & Observations
Yu Uemura,Masahide Yamamoto,Masataka Ishimura,Hirokazu Kanegane,Akihisa Sawada,Akihiro Hirakawa,Ken-Ichi Imadome,Mayumi Yoshimori,Masashi Nagata,Kouhei Yamamoto,Norio Shimizu,Ryuji Koike,Ayako Arai
View Articletitled, JAK1/2 inhibitor ruxolitinib for the treatment of systemic chronic active Epstein-Barr virus disease: a phase 2 study
Supplemental data
Addition of navitoclax to ruxolitinib for patients with myelofibrosis with progression or suboptimal response
Clinical Trials & Observations
Naveen Pemmaraju,Tim C.P. Somervaille,Francesca Palandri,Claire Harrison,Rami S. Komrokji,Andrew Perkins,Rosa M. Ayala Diaz,David Lavie,Akihiro Tomita,Yang Feng,Qin Qin,Jason Harb,Akshanth R. Polepally,Jalaja Potluri,Jacqueline S. Garcia
View Articletitled, Addition of navitoclax to ruxolitinib for patients with myelofibrosis with progression or suboptimal response
Supplemental data
A phase 1 study of interleukin-15 in combination with mogamulizumab in relapsed and refractory T-cell malignancies
Clinical Trials & Observations
Max J. Gordon,Sigrid Dubois,Milos D. Miljkovic,Samuel Ng,Bonita Bryant,Rahul Lakhotia,Christopher Melani,Stefania Pittaluga,Kevin Conlon,Thomas Waldmann,Louis M. Staudt,Wyndham H. Wilson,Mark Roschewski
View Articletitled, A phase 1 study of interleukin-15 in combination with mogamulizumab in relapsed and refractory T-cell malignancies

LYMPHOID NEOPLASIA

Real-world characteristics, treatment patterns, and outcomes of patients with 2 or more LOTs for CLL/SLL in the United States
Matthew S. Davids,Jacob Ambrose,Enrico de Nigris,Jennifer Prescott,Siyang Leng,Mohammed Z. H. Farooqui,Shravanthi R. Gandra,Christina M. Zettler,Laura L. Fernandes,Ching Kun Wang,Mazyar Shadman
View Articletitled, Real-world characteristics, treatment patterns, and outcomes of patients with 2 or more LOTs for CLL/SLL in the United States
Supplemental data
Pralatrexate injection combined with oral leucovorin for mucositis management in PTCL/CTCL treatment: a multicenter phase 2 trial
Swaminathan P. Iyer,Shaker Dakhil,Michi M. Shinohara,Jasmine Zain,Mark Acosta,Francine Foss
View Articletitled, Pralatrexate injection combined with oral leucovorin for mucositis management in PTCL/CTCL treatment: a multicenter phase 2 trial
Cerebrospinal fluid attenuates the efficacy of methotrexate against acute lymphoblastic leukemia cells
Jongseok Kang,Jason Ostergaard,Xiaohong Wang,Peter M. Gordon
View Articletitled, Cerebrospinal fluid attenuates the efficacy of methotrexate against acute lymphoblastic leukemia cells
Supplemental data
Diagnostic genomic analysis is prognostic in AYA patients with ALL treated on an MRD-stratified pediatric protocol
David T. Yeung,Laura N. Eadie,Jacqueline Rehn,Susan L. Heatley,Barbara J. McClure,Elyse C. Page,Caitlin E. Schutz,Michael P. Osborn,Toby Trahair,Rosemary Sutton,Michelle J. Henderson,John Kwan,Sally Mapp,Luciano Dalla-Pozza,Kenneth Bradstock,Matthew Greenwood,Deborah L. White
View Articletitled, Diagnostic genomic analysis is prognostic in AYA patients with ALL treated on an MRD-stratified pediatric protocol
Supplemental data
Single-cell and spatial characterization of plasmablast-like lymphoma cells in primary central nervous system lymphoma
Hiroki Kobayashi,Ryota Chijimatsu,Yusuke Naoi,Yoshihiro Otani,Ryo Mizuta,Kentaro Fujii,Joji Ishida,Hiroyuki Murakami,Hideki Ujiie,Kazuhiro Ikeuchi,Tomohiro Urata,Keisuke Seike,Hideaki Fujiwara,Noboru Asada,Nobuharu Fujii,Ken-ichi Matsuoka,Yasuharu Sato,Yoshinobu Maeda,Daisuke Ennishi
View Articletitled, Single-cell and spatial characterization of plasmablast-like lymphoma cells in primary central nervous system lymphoma
Supplemental data
Loss of p53 impairs death receptor expression and confers resistance to CD19 CAR T-cell therapy in BCP-ALL
Willem P. J. Cox,Noël M. M. Dautzenberg,Linde Dekker,Tesa Klenovsek,Annelisa M. Cornel,Marliek van Hoesel,Dorette S. van Ingen Schenau,Reno S. Bladergroen,Roland P. Kuiper,Laurens T. van der Meer,Friso G. Calkoen,Stefan Nierkens,Frank N. van Leeuwen
View Articletitled, Loss of p53 impairs death receptor expression and confers resistance to CD19 CAR T-cell therapy in BCP-ALL
Supplemental data
Low platelet counts and low CD4/CD8 ratios at apheresis increase the risk of CAR T-cell manufacturing failure in myeloma
Clinical Trials & Observations
Tomoyasu Jo,Kyoko Yoshihara,Masaki Ri,Nobuhiro Tsukada,Naoya Mimura,Keiko Fujii,Kentaro Fukushima,Shin-Ichiro Fujiwara,Yuji Shimura,Kyoko Haraguchi,Koji Kato,Atsushi Satake,Akiyo Yoshida,Rikio Suzuki,Junko Ikemoto,Keita Iwaki,Wataru Takeda,Noboru Yonetani,Ryuji Tanosaki,Minami Yamada-Fujiwara,Kaoru Kahata,Tokiko Nagamura-Inoue,Satoshi Yoshihara,Yasuyuki Arai
View Articletitled, Low platelet counts and low CD4/CD8 ratios at apheresis increase the risk of CAR T-cell manufacturing failure in myeloma
Supplemental data
Population differences in the associations between chromosomal abnormalities and overall survival of multiple myeloma
Bei Wang,Benjamin A. Derman,Madina Sukhanova,Daniel Appelbaum,John Cursio,Wei Zhang,Andrzej Jakubowiak,Brian C.-H. Chiu
View Articletitled, Population differences in the associations between chromosomal abnormalities and overall survival of multiple myeloma

TRANSLATIONAL RESEARCH

Enitociclib, a selective CDK9 inhibitor: in vitro and in vivo preclinical studies in multiple myeloma
Son Tran,Patrick Sipila,Melanie M. Frigault,Beatrix Stelte-Ludwig,Amy J. Johnson,Joseph Birkett,Raquel Izumi,Ahmed Hamdy,Ranjan Maity,Nizar J. Bahlis,Paola Neri,Aru Narendran
View Articletitled, Enitociclib, a selective CDK9 inhibitor: in vitro and in vivo preclinical studies in multiple myeloma
Supplemental data

RESEARCH LETTERS

Pathogenic germ line variants in a prospective multicenter cohort of patients with multiple myeloma
Julia Erin Wiedmeier-Nutor,Michael A. Golafshar,Katie L. Kunze,Edward D. Esplin,Robert L. Nussbaum,Erik Jessen,Brandie Heald,A. Keith Stewart,N. Jewel Samadder,P. Leif Bergsagel,Rafael Fonseca
View Articletitled, Pathogenic germ line variants in a prospective multicenter cohort of patients with multiple myeloma
Supplemental data
Real-world safety profile of therapy with ibrutinib or acalabrutinib in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
Ramsay Hafer,Francesco Iadevaia,Thomas Z. Rohan,Teresa Duong,Maria Poluch,Gina Keiffer,Michael Li,Andres Ferber,Luca Laurenti,Alan S. Khoo,Pierluigi Porcu
View Articletitled, Real-world safety profile of therapy with ibrutinib or acalabrutinib in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
Supplemental data
Outcomes of follicular lymphoma with leukemic phase in the modern era: results from a large multicenter study
Asaad Trabolsi,Sunwoo Han,Narendranath Epperla,Kaitlin Annunzio,Firas Baidoun,Muhamad Alhaj Moustafa,Dan Morgenstern-Kaplan,Peter Doukas,Frederique St-Pierre,Brittany McCall,Lindsey Fitzgerald,Jose Sandoval-Sus,Shivani Dalal,Isildinha M. Reis,Jennifer Rose Chapman-Fredricks,Seo-Hyun Kim,Cherry Au,Natalie B. Otto,Khaled Alhamad,Thomas Ollila,Reem Karmali,Geoffrey Shouse,Izidore S. Lossos,Juan Pablo Alderuccio
View Articletitled, Outcomes of follicular lymphoma with leukemic phase in the modern era: results from a large multicenter study
Supplemental data
  • Cover Image

    Cover Image

    issue cover

    Blood smear of chronic lymphocytic leukemia, analyzed by microscopy. ID 118071357 © Jarun011 | Dreamstime.com.

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