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Journal Articles

TLT-1 Regulates Thrombus Growth Under Non-Inflammatory Conditions

Angela Doerr, Denise Pedrosa, Maria Schander, Yotis A. Senis, Alexandra Mazharian, Anthony Valance Washington, Wolfram Ruf, Thomas Anthony Jude McKinnon

Blood (2021) 138 (Supplement 1): 1050.

https://doi.org/10.1182/blood-2021-152975

Published: 2021

Journal Articles

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

Zoltan Nagy, Jun Mori, Vanesa-Sindi Ivanova, Alexandra Mazharian, Yotis A. Senis

Blood (2020) 135 (18): 1574–1587.

https://doi.org/10.1182/blood.2019002848

Published: 2020

Includes: Supplemental data

Journal Articles

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

Marie Bellio, Cédric Garcia, Thomas Edouard, Sophie Voisin, Benjamin G. Neel, Cendrine Cabou, Philippe Valet, Jun Mori, Alexandra Mazharian, Yotis A. Senis, Armelle Yart, Bernard Payrastre, Sonia Severin

Blood (2019) 134 (25): 2304–2317.

https://doi.org/10.1182/blood.2019001543

Published: 2019

Includes: Supplemental data

Journal Articles

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Zoltan Nagy, Timo Vögtle, Mitchell J. Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G. Neel, Guillaume E. Desanti, Alexandra Mazharian, Yotis A. Senis

Blood (2019) 133 (4): 331–343.

https://doi.org/10.1182/blood-2018-09-877787

Published: 2019

Includes: Supplemental data

Journal Articles

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

Mitchell J. Geer, Johanna P. van Geffen, Piraveen Gopalasingam, Timo Vögtle, Christopher W. Smith, Silke Heising, Marijke J. E. Kuijpers, Bibian M. E. Tullemans, Gavin E. Jarvis, Johannes A. Eble, Mark Jeeves, Michael Overduin, Johan W. M. Heemskerk, Alexandra Mazharian, Yotis A. Senis

Blood (2018) 132 (13): 1413–1425.

https://doi.org/10.1182/blood-2017-10-802975

Published: 2018

Includes: Supplemental data

Journal Articles

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

Blood (2018) 132 (13): 1399–1412.

https://doi.org/10.1182/blood-2017-08-802769

Published: 2018

Includes: Supplemental data

Journal Articles

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148

Blood (2018) 131 (10): 1122–1144.

https://doi.org/10.1182/blood-2017-02-768077

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Proplatelets slip slidin’ away

Alexandra Mazharian, Yotis A. Senis

Blood (2015) 125 (5): 747–748.

https://doi.org/10.1182/blood-2014-12-614131

Published: 2015

Journal Articles

Src family kinases: at the forefront of platelet activation

Yotis A. Senis, Alexandra Mazharian, Jun Mori

Blood (2014) 124 (13): 2013–2024.

https://doi.org/10.1182/blood-2014-01-453134

Published: 2014

Journal Articles

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Catherine M. Hobbs, Harriet Manning, Cavan Bennett, Louella Vasquez, Sonia Severin, Lauren Brain, Alexandra Mazharian, Jose A. Guerrero, Juan Li, Nicole Soranzo, Anthony R. Green, Steve P. Watson, Cedric Ghevaert

Blood (2013) 122 (23): 3787–3797.

https://doi.org/10.1182/blood-2013-06-501452

Published: 2013

Includes: Supplemental data

Journal Articles

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P)

Lin Zhang, Nicole Urtz, Florian Gaertner, Kyle R. Legate, Tobias Petzold, Michael Lorenz, Alexandra Mazharian, Steve P. Watson, Steffen Massberg

Blood (2013) 122 (5): 791–802.

https://doi.org/10.1182/blood-2012-12-473884

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Alexandra Mazharian, Jun Mori, Ying-Jie Wang, Silke Heising, Benjamin G. Neel, Steve P. Watson, Yotis A. Senis

Blood (2013) 121 (20): 4205–4220.

https://doi.org/10.1182/blood-2012-08-449272

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

Alexandra Mazharian, Cedric Ghevaert, Lin Zhang, Steffen Massberg, Steve P. Watson

Blood (2011) 117 (19): 5198–5206.

https://doi.org/10.1182/blood-2010-12-326850

Published: 2011

Includes: Supplemental data

Journal Articles

Critical role of Src-Syk-PLCγ2 signaling in megakaryocyte migration and thrombopoiesis

Alexandra Mazharian, Steve G. Thomas, Tarvinder S. Dhanjal, Christopher D. Buckley, Steve P. Watson

Blood (2010) 116 (5): 793–800.

https://doi.org/10.1182/blood-2010-03-275990

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

Yotis A. Senis, Michael G. Tomlinson, Stuart Ellison, Alexandra Mazharian, Jenson Lim, Yan Zhao, Kristin N. Kornerup, Jocelyn M. Auger, Steve G. Thomas, Tarvinder Dhanjal, Neena Kalia, Jing W. Zhu, Arthur Weiss, Steve P. Watson

Blood (2009) 113 (20): 4942–4954.

https://doi.org/10.1182/blood-2008-08-174318

Published: 2009

Includes: Multimedia, Supplemental data

NARROW

TLT-1 Regulates Thrombus Growth Under Non-Inflammatory Conditions

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148

Proplatelets slip slidin’ away

Src family kinases: at the forefront of platelet activation

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P)

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

Critical role of Src-Syk-PLCγ2 signaling in megakaryocyte migration and thrombopoiesis

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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