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Carl Sandén
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Journal Articles

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Pablo Peña-Martínez, Ludvig Sjöström, Helena Ågerstam, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Jan Pronk, Kjeld Schmiegelow, Axel Hyrenius-Wittsten, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos
Journal: Blood
Blood (2024) 144 (13): 1399–1411.
https://doi.org/10.1182/blood.2023021705
Published: 2024
Includes: Supplemental data
Journal Articles

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Ludvig Sjöström, Helena Ågerstam, Pablo Enrique Peña-Martínez, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Vibeke Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Pronk, Kjeld Schmiegelow, Axel Hyrenius Wittsten, Christina Orsmark-Pietras, Henrik PhD Lilljebjörn, Thoas Fioretos
Journal: Blood
Blood (2023) 142 (Supplement 1): 842.
https://doi.org/10.1182/blood-2023-173350
Published: 2023
Journal Articles

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos
Journal: Blood
Blood (2022) 140 (Supplement 1): 3467–3468.
https://doi.org/10.1182/blood-2022-163031
Published: 2022
Journal Articles

AML Xenografts Undergo Extensive Clonal Competition and Unmask Rare Clones in Patient Samples

Carl Sandén, PhD, Henrik Lilljebjörn, PhD, Christina Orsmark-Pietras, PhD, Karim Saba, MSc, Carl Högberg, PhD, Marianne Rissler, MSc, Vladimir Lazarevic, MD PhD, Gunnar Juliusson, MD PhD, Helena Ågerstam, PhD, Thoas Fioretos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2621.
https://doi.org/10.1182/blood-2018-99-110497
Published: 2018
Journal Articles

CDK8 Inhibitor SEL120-34A Has Therapeutic Efficacy in Murine and Human Acute Myeloid Leukemia Models

Marion Chapellier, PhD, Jun Chen, MD PhD, Carl Sandén, PhD, Milena Mazan, PhD, Eliza Majewska, Katarzyna Wiklik, PhD, Michal Combik, PhD, Magdalena Masiejczyk, MSc, Elzbieta Fiedor, Marta Obacz, Anna Polak, Arkadiusz Bialas, Paulina Chesy, Ewelina Gabor-Worwa, Przemyslaw Juszczynski, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Thoas Fioretos, MD PhD, Johan Flygare, MD PhD, Marcus Jaras, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1520.
https://doi.org/10.1182/blood-2018-99-111859
Published: 2018
Journal Articles

IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Helena Ågerstam, Nils Hansen, Sofia von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, Marcus Järås, Thoas Fioretos
Journal: Blood
Blood (2016) 128 (23): 2683–2693.
https://doi.org/10.1182/blood-2015-11-679985
Published: 2016
Includes: Supplemental data
Journal Articles

Mutational and Clonal Dynamics in Patient-Derived Xenografts of Acute Myeloid Leukemia

Carl Sandén, Karim Saba, Christina Orsmark-Pietras, Henrik Lilljebjörn, Carl Högberg, Marianne Rissler, Vladimir Lazarevic, Gunnar Juliusson, Helena Ågerstam, Thoas Fioretos
Journal: Blood
Blood (2016) 128 (22): 1154.
https://doi.org/10.1182/blood.V128.22.1154.1154
Published: 2016
Journal Articles

IL1RAP Antibodies Block IL1-Induced Expansion of Primitive CML Cells and Display Therapeutic Effects in Xenograft Models

Helena Ågerstam, Nils Hansen, Sofia Von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, MD, Marcus Järås, Thoas Fioretos
Journal: Blood
Blood (2016) 128 (22): 1118.
https://doi.org/10.1182/blood.V128.22.1118.1118
Published: 2016