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Christelle Dousset
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Journal Articles

A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals a major role of BAX in the response to BH3 mimetics

Romane Durand, Géraldine Descamps, Céline Bellanger, Christelle Dousset, Sophie Maïga, Jean-Baptiste Alberge, Jennifer Derrien, Jonathan Cruard, Stéphane Minvielle, Nicoletta Libera Lilli, Catherine Godon, Yannick Le Bris, Benoit Tessoulin, Martine Amiot, Patricia Gomez-Bougie, Cyrille Touzeau, Philippe Moreau, David Chiron, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck
Journal: Blood
Blood (2024) 143 (13): 1242–1258.
https://doi.org/10.1182/blood.2023021581
Published: 2024
Includes: Supplemental data
Journal Articles

CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma

Salomé Decombis, Celine Bellanger, Yannick Le Bris, Candice Madiot, Jane Jardine, Juliana Carvalho Santos, Delphine Boulet, Christelle Dousset, Audrey Menard, Charlotte Kervoelen, Elise Douillard, Philippe Moreau, Stephane Minvielle, Agnes Moreau-Aubry, Benoit Tessoulin, Gael Roue, Nicolas Bidère, Steven Le Gouill, Catherine Pellat-Deceunynck, David Chiron
Journal: Blood
Blood (2023) 142 (18): 1543–1555.
https://doi.org/10.1182/blood.2023020211
Published: 2023
Includes: Supplemental data
Journal Articles

CARD11 and BCL2A1 Join Forces to Promote Resistance to Ibrutinib/Venetoclax Combination in Lymphoma Patients

Salomé Decombis, Celine Bellanger, Yannick Le Bris, Delphine Boulet, Jane Jardine, Christelle Dousset, Audrey Ménard, Charlotte Kervoelen, Elise Douillard, Philippe Moreau, Stephane Minvielle, Agnes Moreau-Aubry, Benoit Tessoulin, Nicolas Bidère, Steven Le Gouill, Catherine Pellat-Deceunynck, David Chiron
Journal: Blood
Blood (2022) 140 (Supplement 1): 2044–2045.
https://doi.org/10.1182/blood-2022-157694
Published: 2022
Journal Articles

TP53 CRISPR/Cas9 Reveals Strict BAX Dependence in the Response to BH3 Mimetic Targeting MCL1

Romane Durand, Domitille Costes-Tertrais, Geraldine Descamps, Christelle Dousset, Sophie Maïga, Jean-Baptiste Alberge, Elise Douillard, Jennifer Derrien, Celine Bellanger, David Chiron, Stephane Minvielle, Cyrille Touzeau, Philippe Moreau, Martine Amiot, Patricia Gomez-Bougie, Agnes Moreau-Aubry, Catherine Pellat-Deceunynck
Journal: Blood
Blood (2022) 140 (Supplement 1): 4198–4199.
https://doi.org/10.1182/blood-2022-155862
Published: 2022
Journal Articles

The IL32/BAFF Axis Supports Prosurvival Dialog in the Lymphoma Ecosystem and Is Disrupted By NIK Inhibition

Salome Decombis, Antonin Papin, Celine Bellanger, Clara Sortais, Christelle Dousset, Yannick Le Bris, Stephanie Blandin, Philippe Hulin, Benoit Tessoulin, Mathieu Rouel, Steven Le Gouill, Agnes Moreau-Aubry, Catherine Pellat-Deceunynck, David Chiron
Journal: Blood
Blood (2021) 138 (Supplement 1): 781.
https://doi.org/10.1182/blood-2021-144839
Published: 2021
Journal Articles

Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma

David Chiron, Céline Bellanger, Antonin Papin, Benoit Tessoulin, Christelle Dousset, Sophie Maiga, Anne Moreau, Julie Esbelin, Valérie Trichet, Selina Chen-Kiang, Philippe Moreau, Cyrille Touzeau, Steven Le Gouill, Martine Amiot, Catherine Pellat-Deceunynck
Journal: Blood
Blood (2016) 128 (24): 2808–2818.
https://doi.org/10.1182/blood-2016-06-720490
Published: 2016
Includes: Supplemental data
Journal Articles

Lymphoid-like Environment, Which Promotes Proliferation and Induces Resistance to BH3-Mimetics, Is Counteracted By Obinutuzumab in MCL: Biological Rationale for the Oasis Clinical Trial

David Chiron, PhD, Celine Bellanger, Antonin Papin, Benoit Tessoulin, MD, Christelle Dousset, Sophie Maiga, Anne Moreau, MD, Julie Esbelin, MD, Valerie Trichet, PhD, Selina Chen-Kiang, PhD, Philippe Moreau, Cyrille Touzeau, MD, Steven Le Gouill, MD PhD, Martine Amiot, Catherine Pellat-Deceunynck, PhD
Journal: Blood
Blood (2016) 128 (22): 1096.
https://doi.org/10.1182/blood.V128.22.1096.1096
Published: 2016
Journal Articles

Mantle-Cell Lymphoma (MCL) Cells Are Highly Sensitive To ABT-199 But Their Sensitivity May Be Altered By The Microenvironment Via The Up-Regulation Of Bcl-Xl and Bcl2A1

Cyrille Touzeau, MD, Carole Brosseau, PhD, Christelle Dousset, Catherine Pellat-Deceunynck, PhD, Steven Le Gouill, MD, PhD, Martine Amiot, PhD
Journal: Blood
Blood (2013) 122 (21): 4285.
https://doi.org/10.1182/blood.V122.21.4285.4285
Published: 2013
Journal Articles

Vitamin D3 and Lenalidomide Synergize To Induce Apoptosis In Mantle Cell Lymphoma Via Demethylation Of BIK

Carole Brosseau, PhD, Christelle Dousset, Cyrille Touzeau, MD, Sophie Maiga, Philippe Moreau, MD, Martine Amiot, PhD, Steven Le Gouill, MD, PhD, Catherine Pellat-Deceunynck, PhD
Journal: Blood
Blood (2013) 122 (21): 1830.
https://doi.org/10.1182/blood.V122.21.1830.1830
Published: 2013
Journal Articles

ABT-737 is highly effective against molecular subgroups of multiple myeloma

Linda Bodet, Patricia Gomez-Bougie, Cyrille Touzeau, Christelle Dousset, Géraldine Descamps, Sophie Maïga, Hervé Avet-Loiseau, Régis Bataille, Philippe Moreau, Steven Le Gouill, Catherine Pellat-Deceunynck, Martine Amiot
Journal: Blood
Blood (2011) 118 (14): 3901–3910.
https://doi.org/10.1182/blood-2010-11-317438
Published: 2011
Includes: Supplemental data
Journal Articles

Rational for the Use of a Targeted-Therapy Using ABT-737 In Mantle-Cell Lymphoma

Cyrille Touzeau, Christelle Dousset, Lynda Bodet, Stephanie Bonnaud, Patricia Gomez-Bougie, Thomas Gastinne, Soraya Wuilleme, Anne Moreau, Philippe Moreau, Catherine Pellat-Deceunynck, PhD, Martine Amiot, Steven Le Gouill
Journal: Blood
Blood (2010) 116 (21): 770.
https://doi.org/10.1182/blood.V116.21.770.770
Published: 2010
Journal Articles

High Bcl-2/Mcl-1 Gene Expression Ratio Identifies Molecular Sub-Groups of Multiple Myeloma Patients Extremely Sensitive to ABT-737

Linda Bodet, Catherine Pellat-Deceunynck, PhD, Patricia Gomez-Bougie, PhD, Christelle Dousset, Cyrille Touzeau, Steven Le Gouill, MD, PhD, Hervé Avet-Loiseau, MD, PhD, Regis Bataille, MD, PhD, Martine Amiot, PhD
Journal: Blood
Blood (2010) 116 (21): 4061.
https://doi.org/10.1182/blood.V116.21.4061.4061
Published: 2010