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Journal Articles

Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML

Bing Z. Carter, Duncan H. Mak, Wendy D. Schober, Erich Koller, Clemencia Pinilla, Lyubomir T. Vassilev, John C. Reed, Michael Andreeff

Blood (2010) 115 (2): 306–314.

https://doi.org/10.1182/blood-2009-03-212563

Published: 2010

Includes: Supplemental data

Journal Articles

Simultaneous Activation of p53 and Inhibition of XIAP Enhance the Activation of Apoptosis Signaling Pathways in AML.

Bing Z. Carter, PhD, Duncan H. Mak, Wendy D. Schober, Erich Koller, PhD, Clemencia Pinilla, PhD, Lyubomir T. Vassilev, PhD, John C. Reed, MD, PhD, Michael Andreeff, MD, PhD

Blood (2008) 112 (11): 1941.

https://doi.org/10.1182/blood.V112.11.1941.1941

Published: 2008

Journal Articles

Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5

Bing Z. Carter, Duncan H. Mak, Wendy D. Schober, Martin F. Dietrich, Clemencia Pinilla, Lyubomir T. Vassilev, John C. Reed, Michael Andreeff

Blood (2008) 111 (7): 3742–3750.

https://doi.org/10.1182/blood-2007-05-091504

Published: 2008

Journal Articles

Small-molecule XIAP antagonist restores caspase-9–mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells

Saskia A. G. M. Cillessen, John C. Reed, Kate Welsh, Clemencia Pinilla, Richard Houghten, Erik Hooijberg, José Deurhof, Kitty C. M. Castricum, Pim Kortman, Corine J. Hess, Gert J. Ossenkoppele, Chris J. L. M. Meijer, Joost J. Oudejans

Blood (2008) 111 (1): 369–375.

https://doi.org/10.1182/blood-2007-04-085480

Published: 2008

Journal Articles

Small-Molecule XIAP Antagonist Restores Caspase-9-Mediated Apoptosis in XIAP-Positive Diffuse Large B-Cell Lymphoma Cells.

Saskia A.G.M. Cillessen, MSc, John C. Reed, PhD MD, Clemencia Pinilla, PhD, Chris J.L.M. Meijer, PhD MD, Erik Hooijberg, PhD, Corine J. Hess, MD, Kitty C.M. Castricum, Pim Kortman, Gert J. Ossenkoppele, PhD MD, Joost J. Oudejans, PhD MD

Blood (2007) 110 (11): 803.

https://doi.org/10.1182/blood.V110.11.803.803

Published: 2007

Journal Articles

Triptolide Sensitizes Leukemic Cells to TRAIL Induced Apoptosis Via Decrease of XIAP and p53-Mediated Increase of DR5.

Bing Z. Carter, PhD, Duncan H. Mak, Wendy D. Schober, Martin Dietrich, Clemencia Pinilla, Ph.D., John C. Reed, M.D., Ph.D., Michael Andreeff, M.D., Ph.D.

Blood (2006) 108 (11): 528.

https://doi.org/10.1182/blood.V108.11.528.528

Published: 2006

Journal Articles

AML Progenitor/Stem Cells Overexpress XIAP and Are Sensitive to the Small Molecular XIAP Inhibitor 1396-11.

Bing Z. Carter, PhD, Tae Kon Kim, Duncan H. Mak, Wei Hu, Clemencia Pinilla, Ph.D., John C. Reed, M.D., Ph.D., Michael Andreeff, M.D., Ph.D.

Blood (2006) 108 (11): 2586.

https://doi.org/10.1182/blood.V108.11.2586.2586

Published: 2006

Journal Articles

Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis

Arnon P. Kater, Frank Dicker, Massimo Mangiola, Kate Welsh, Richard Houghten, John Ostresh, Adel Nefzi, John C. Reed, Clemencia Pinilla, Thomas J. Kipps

Blood (2005) 106 (5): 1742–1748.

https://doi.org/10.1182/blood-2005-02-0695

Published: 2005

Journal Articles

Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells

Blood (2005) 105 (10): 4043–4050.

https://doi.org/10.1182/blood-2004-08-3168

Published: 2005

Journal Articles

Small-Molecule XIAP Inhibitors Derepress Downstream Effector Caspases and Induce Apoptosis of Leukemia Cell Lines and Patient Samples.

Aaron D. Schimmer, MD, PhD, Marcela Gronda, MSc, Zhiliang Wang, PhD, Kate Welsh, PhD, Clemencia Pinilla, PhD, Michael Andreeff, MD, PhD, Wendy D. Schober, Adel Nefzi, PhD, Richard Houghten, PhD, Joseph Brandwein, MD, Mark D. Minden, MD, PhD, Andre Schuh, MD, PhD, Richard A. Wells, MD, PhD, Hans Messner, MD, PhD, John C. Reed, MD, PhD, Bing Z. Carter, PhD

Blood (2004) 104 (11): 759.

https://doi.org/10.1182/blood.V104.11.759.759

Published: 2004

Journal Articles

Inhibition of XIAP Renders Newly CD40-Activated Chronic Lymphocytic Leukemia Cells Sensitive to Fas (CD95) Mediated Apoptosis.

Arnon P. Kater, MD, Frank Dicker, PhD, Massimo Mangiola, PhD, Kate Welsh, John Ostresh, PhD, Richard Houghten, PhD, John C. Reed, MD, PhD, Thomas J. Kipps, MD, PhD, Clemencia Pinilla, PhD

Blood (2004) 104 (11): 3474.

https://doi.org/10.1182/blood.V104.11.3474.3474

Published: 2004

Journal Articles

Inhibition of XIAP Enhances Specific Cytotoxic T Lymphocyte (CTL) Killing and CD20-Directed Antibody-Dependent Cellular Cytotoxicity of Chronic Lymphocytic Leukemia B Cells.

Arnon P. Kater, MD, Roman Rieger, PhD, Kate Welsh, PhD, Adel Nefzi, PhD, Richard Houghten, PhD, John C. Reed, MD. PhD, Clemencia Pinilla, PhD, Thomas J. Kipps, MD, PhD

Blood (2004) 104 (11): 3475.

https://doi.org/10.1182/blood.V104.11.3475.3475

Published: 2004

Journal Articles

Enhanced immune activity of cytotoxic T-lymphocyte epitope analogs derived from positional scanning synthetic combinatorial libraries

Corinna La Rosa, Radhika Krishnan, Susan Markel, Jonathan P. Schneck, Richard Houghten, Clemencia Pinilla, Don J. Diamond

Blood (2001) 97 (6): 1776–1786.

https://doi.org/10.1182/blood.V97.6.1776

Published: 2001

NARROW

Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML

Simultaneous Activation of p53 and Inhibition of XIAP Enhance the Activation of Apoptosis Signaling Pathways in AML.

Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5

Small-molecule XIAP antagonist restores caspase-9–mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells

Small-Molecule XIAP Antagonist Restores Caspase-9-Mediated Apoptosis in XIAP-Positive Diffuse Large B-Cell Lymphoma Cells.

Triptolide Sensitizes Leukemic Cells to TRAIL Induced Apoptosis Via Decrease of XIAP and p53-Mediated Increase of DR5.

AML Progenitor/Stem Cells Overexpress XIAP and Are Sensitive to the Small Molecular XIAP Inhibitor 1396-11.

Inhibitors of XIAP sensitize CD40-activated chronic lymphocytic leukemia cells to CD95-mediated apoptosis

Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells

Small-Molecule XIAP Inhibitors Derepress Downstream Effector Caspases and Induce Apoptosis of Leukemia Cell Lines and Patient Samples.

Inhibition of XIAP Renders Newly CD40-Activated Chronic Lymphocytic Leukemia Cells Sensitive to Fas (CD95) Mediated Apoptosis.

Inhibition of XIAP Enhances Specific Cytotoxic T Lymphocyte (CTL) Killing and CD20-Directed Antibody-Dependent Cellular Cytotoxicity of Chronic Lymphocytic Leukemia B Cells.

Enhanced immune activity of cytotoxic T-lymphocyte epitope analogs derived from positional scanning synthetic combinatorial libraries

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American Society of Hematology

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American Society of Hematology

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