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Craig M. Crews
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Journal Articles

Mechanistic basis and efficacy of targeting the β-catenin–TCF7L2–JMJD6–c-Myc axis to overcome resistance to BET inhibitors

Dyana T. Saenz, Warren Fiskus, Christopher P. Mill, Dimuthu Perera, Taghi Manshouri, Bernardo H. Lara, Vrajesh Karkhanis, Sunil Sharma, Stephen K. Horrigan, Prithviraj Bose, Tapan M. Kadia, Lucia Masarova, Courtney D. DiNardo, Gautam Borthakur, Joseph D. Khoury, Koichi Takahashi, Srividya Bhaskara, Charles Y. Lin, Michael R. Green, Cristian Coarfa, Craig M. Crews, Srdan Verstovsek, Kapil N. Bhalla
Journal: Blood
Blood (2020) 135 (15): 1255–1269.
https://doi.org/10.1182/blood.2019002922
Published: 2020
Includes: Supplemental data
Journal Articles

RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1

Christopher P. Mill, Warren Fiskus, Courtney D. DiNardo, Yimin Qian, Kanak Raina, Kimal Rajapakshe, Dimuthu Perera, Cristian Coarfa, Tapan M. Kadia, Joseph D. Khoury, Dyana T. Saenz, David N. Saenz, Anuradha Illendula, Koichi Takahashi, Steven M. Kornblau, Michael R. Green, Andrew P. Futreal, John H. Bushweller, Craig M. Crews, Kapil N. Bhalla
Journal: Blood
Blood (2019) 134 (1): 59–73.
https://doi.org/10.1182/blood.2018893982
Published: 2019
Includes: Supplemental data
Journal Articles

Preclinical Activity of Novel BET Protein Proteolysis Targeting Chimeras (BETP-PROTACs) and Their Combination with Venetoclax or CDK4/6 Inhibitor Against Human Mantle Cell Lymphoma (MCL) Cells

Baohua Sun, MD PhD, Warren Fiskus, BSc,PhD, Kanak Raina, PhD, Yimin Qian, PhD, Andrew Crew, Dyana T. Saenz, PhD, Christopher Peter Mill, PhD BA, Agnieszka J Nowak, David N Saenz, Craig M Crews, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1265.
https://doi.org/10.1182/blood.V130.Suppl_1.1265.1265
Published: 2017
Journal Articles

Targeted Therapy with BET Protein and β Catenin Antagonists Against Ruxolitinib Resistant Post-Myeloproliferative Neoplasm (MPN) Secondary (s) AML Cells

Dyana T. Saenz, PhD, Warren Fiskus, BSc,PhD, Taghi Manshouri, Yimin Qian, PhD, Kanak Raina, PhD, David N Saenz, Christopher Peter Mill, PhD BA, Agnieszka J Nowak, Baohua Sun, MD PhD, Srdan Verstovsek, MD PhD, Craig M Crews, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1239.
https://doi.org/10.1182/blood.V130.Suppl_1.1239.1239
Published: 2017
Journal Articles

BRD4 Proteolysis Targeting Chimera (PROTAC) ARV-825 Targets Both NOTCH1-MYC Regulatory Circuit and Leukemia-Microenvironment in T-ALL

Sujan Piya, PhD, Hong Mu, MD PhD, Seemana Bhattacharya, PhD, Teresa McQueen, MS, Richard E Davis, BSPharm, MS, Vivian Ruvolo, PhD, Natalia Baran, PhD MD, Yimin Qian, PhD, Kanak Raina, PhD, Craig M Crews, PhD, M. James You, MD PhD, Patrick Zweider McKay, MDPhD, Marina Konopleva, MD PhD, Hagop M. Kantarjian, MD, Michael Andreeff, MD PhD, Gautam Borthakur, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 716.
https://doi.org/10.1182/blood.V130.Suppl_1.716.716
Published: 2017
Journal Articles

Targeted Therapy for AML Expressing RUNX1 Mutation

Christopher Peter Mill, PhD BA, Warren Fiskus, BSc,PhD, Courtney D. DiNardo, MDMSc, Yimin Qian, PhD, Kanak Raina, PhD, Koichi Takahashi, MD, Tapan Kadia, MD, Dyana T. Saenz, PhD, Agnieszka J Nowak, Baohua Sun, MD PhD, Craig M Crews, PhD, Kapil N. Bhalla, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2472.
https://doi.org/10.1182/blood.V130.Suppl_1.2472.2472
Published: 2017