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Cristina Puy
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Journal Articles

Coagulation factor XI regulates endothelial cell permeability and barrier function in vitro and in vivo

Cristina Puy, Samantha A. Moellmer, Jiaqing Pang, Helen H. Vu, Alexander R. Melrose, Christina U. Lorentz, Erik I. Tucker, Joseph J. Shatzel, Ravi S. Keshari, Florea Lupu, David Gailani, Owen J. T. McCarty
Journal: Blood
Blood (2024) 144 (17): 1821–1833.
https://doi.org/10.1182/blood.2023022257
Published: 2024
Includes: Supplemental data
Journal Articles

Biology of factor XI

Samantha A. Moellmer, Cristina Puy, Owen J. T. McCarty
Journal: Blood
Blood (2024) 143 (15): 1445–1454.
https://doi.org/10.1182/blood.2023020719
Published: 2024
Journal Articles

Antiplatelet Effects of Inhibiting Coagulation Factor XI in a Diet-Induced Obesity Model of Early Atherosclerosis

Tia CL Kohs, Iván Parra-Izquierdo, Helen Vu, Monica T Hinds, Joseph J Shatzel, Joseph E Aslan, Michael Wallisch, Erik I Tucker, Christina U Lorentz, Cristina Puy, David Gailani, Owen JT McCarty
Journal: Blood
Blood (2022) 140 (Supplement 1): 8437.
https://doi.org/10.1182/blood-2022-170472
Published: 2022
Journal Articles

Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus

Robert Silasi, Ravi S. Keshari, Girija Regmi, Cristina Lupu, Constantin Georgescu, Joe H. Simmons, Michael Wallisch, Tia C. L. Kohs, Joseph J. Shatzel, Sven R. Olson, Christina U. Lorentz, Cristina Puy, Erik I. Tucker, David Gailani, Sidney Strickland, András Gruber, Owen J. T. McCarty, Florea Lupu
Journal: Blood
Blood (2021) 138 (2): 178–189.
https://doi.org/10.1182/blood.2020009345
Published: 2021
Includes: Supplemental data
Journal Articles

Proteolytic Inactivation of ADAMTS13 By Activated Factor XI

Kathleen Garland, MD, Owen J.T. McCarty, PhD, Cristina Puy, PhD
Journal: Blood
Blood (2016) 128 (22): 4955.
https://doi.org/10.1182/blood.V128.22.4955.4955
Published: 2016
Journal Articles

Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor

Cristina Puy, Erik I. Tucker, Anton Matafonov, Qiufang Cheng, Keith D. Zientek, Dave Gailani, András Gruber, Owen J. T. McCarty
Journal: Blood
Blood (2015) 125 (9): 1488–1496.
https://doi.org/10.1182/blood-2014-10-604587
Published: 2015
Includes: Supplemental data
Journal Articles

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

Anton Matafonov, Philberta Y. Leung, Adam E. Gailani, Stephanie L. Grach, Cristina Puy, Qiufang Cheng, Mao-fu Sun, Owen J. T. McCarty, Erik I. Tucker, Hiroaki Kataoka, Thomas Renné, James H. Morrissey, Andras Gruber, David Gailani
Journal: Blood
Blood (2014) 123 (11): 1739–1746.
https://doi.org/10.1182/blood-2013-04-499111
Published: 2014
Includes: Supplemental data
Journal Articles

FXII Promotes Coagulation in a FXI and FIX Independent Manner

Cristina Puy, PhD, Zoë C Wong, Erik I Tucker, PhD, Andras Gruber, MD, David Gailani, MD, Stephanie A. Smith, DVM, MS, Sharon H. Choi, MS, James H. Morrissey, PhD, Owen J.T. McCarty, PhD
Journal: Blood
Blood (2012) 120 (21): 3362.
https://doi.org/10.1182/blood.V120.21.3362.3362
Published: 2012
Journal Articles

sPLA 2 -V inhibits EPCR anticoagulant and antiapoptotic properties by accommodating lysophosphatidylcholine or PAF in the hydrophobic groove

Jacinto López-Sagaseta, Cristina Puy, Ibai Tamayo, Mikel Allende, Jorge Cerveró, Susana E. Velasco, Charles T. Esmon, Ramón Montes, José Hermida
Journal: Blood
Blood (2012) 119 (12): 2914–2921.
https://doi.org/10.1182/blood-2011-05-353409
Published: 2012
Includes: Supplemental data