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Journal Articles

Nilotinib (Tasigna ® ) and Low Intensity Chemotherapy for First-Line Treatment of Elderly Patients with BCR-ABL1- Positive Acute Lymphoblastic Leukemia: Final Results of a Prospective Multicenter Trial (EWALL-PH02)

Blood (2018) 132 (Supplement 1): 31.

https://doi.org/10.1182/blood-2018-99-114552

Published: 2018

Journal Articles

Comorbidities Are Frequent in Older Patients with De Novo Acute Lymphoblastic Leukemia (ALL) and Correlate with Induction Mortality: Analysis of More Than 1200 Patients from GMALL Data Bases

Blood (2018) 132 (Supplement 1): 660.

https://doi.org/10.1182/blood-2018-99-111954

Published: 2018

Journal Articles

CD20 Expression and Response to Rituximab Treatment in B-Cell Precursor Lymphoblastic Leukemia - Results of the GMALL 08/2013 Trial

Monika Szczepanowski, PhD, Johanna Richter, Britta Kehden, Matthias Ritgen, MD, Heiko Trautmann, PhD, Henrik Knecht, PhD, Mustafa Kondakci, MD, Christoph Faul, MD, Björn Steffen, MD, Andreas Viardot, MD, Michael Kneba, Dieter Hoelzer, MD PhD, Nicola Goekbuget, MD, Monika Brüggemann

Blood (2018) 132 (Supplement 1): 1409.

https://doi.org/10.1182/blood-2018-99-114673

Published: 2018

Journal Articles

Monitoring of the Clonal Architecture of B-Cell Precursor ALL during Induction Chemoimmunotherapy

Michaela Kotrova, MD PhD, Monika Szczepanowski, PhD, Henrik Knecht, PhD, Christoph Faul, MD, Mustafa Kondakci, MD, Björn Steffen, MD, Andreas Viardot, MD, Michael Kneba, Dieter Hoelzer, MD PhD, Nicola Goekbuget, MD, Nikos Darzentas, PhD, Monika Brüggemann

Blood (2018) 132 (Supplement 1): 1555.

https://doi.org/10.1182/blood-2018-99-112844

Published: 2018

Journal Articles

Evaluation of Minimal Residual Disease (MRD) and MRD-Based Treatment Decisions in Ph/BCR-ABL Negative Adult Acute Lymphoblastic Leukemia (ALL): Experience from the German Multicenter Study Group for Adult ALL (GMALL)

Nicola Goekbuget, MD, Monika Brüggemann, Joachim Beck, MD, Christoph Faul, MD, Christian Koenecke, MD, Heinz A. Horst, MD PhD, Mustafa Kondakci, MD, Doris M. Kraemer, MD, PhD, Christoph Lutz, MD, Bernd Spriewald, MD, Michael Starck, MD, Christoph Rollig, MD MSC, Matthias Stelljes, MD, Andreas Viardot, MD, Ralph Wäsch, Knut Wendelin, MD, Hubert Serve, Michael Kneba, MD, Dieter Hoelzer, MD PhD

Blood (2017) 130 (Supplement 1): 139.

https://doi.org/10.1182/blood.V130.Suppl_1.139.139

Published: 2017

Journal Articles

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

Martin Neumann, Michael P Schroeder, PhD, Lorenz Bastian, Jutta Ortiz Tanchez, Cornelia Schlee, Konstandina Isaakidis, Alva Rani James, Lars R. Fransecky, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Stefan Schwartz, MD, Thomas Burmeister, Dieter Hoelzer, MD PhD, Philipp A. Greif, MD, Monika Brüggemann, Nicola Goekbuget, MD, Claudia D. Baldus, MD

Blood (2017) 130 (Supplement 1): 2725.

https://doi.org/10.1182/blood.V130.Suppl_1.2725.2725

Published: 2017

Journal Articles

The Role of Microrna-196a-1 and Microrna-196b in Acute T-Lymphoblastic Leukemia and Acute Myeloid Leukemia.

Ebru Coskun, MS, Eva Kristin von der Heide, Cornelia Schlee, MS, Nicola Goekbuget, Dieter Hoelzer, MD, PhD, Wolf-Karsten Hofmann, Eckhard Thiel, MD, PhD, Claudia D Baldus

Blood (2009) 114 (22): 1607.

https://doi.org/10.1182/blood.V114.22.1607.1607

Published: 2009

Journal Articles

Overexpression of BAALC Indicates Drug Resistance and Inferior Survival in Adult B-Precursor Acute Lymphoblastic Leukemia.

Andrea Kühnl, Nicola Gökbuget, MD, Andrea Stroux, Thomas Burmeister, MD, Martin Neumann, Sandra Heesch, MS, Torsten Haferlach, MD, Dieter Hoelzer, MD, PhD, Wolf Karsten Hofmann, MD, PhD, Eckhard Thiel, MD, Claudia D Baldus, MD

Blood (2009) 114 (22): 1581.

https://doi.org/10.1182/blood.V114.22.1581.1581

Published: 2009

Journal Articles

Serial Analysis of BCR-ABL Kinase Domain Mutations Prior to and During Imatinib Treatment for Newly Diagnosed and Recurrent BCR-ABL Positive Acute Lymphoblastic Leukemia.

Heike Pfeifer, Sylvia Wystub, Barbara Wassmann, Jaqueline Maier, PhD, Thoralf Lange, MD, Andreas Hochhaus, MD, Dieter Hoelzer, MD, PhD, Oliver Ottmann

Blood (2009) 114 (22): 2041.

https://doi.org/10.1182/blood.V114.22.2041.2041

Published: 2009

Journal Articles

Imatinib and Interferon-Alpha Maintenance Therapy for Patients with Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Ineligible for Allogeneic Stem Cell Transplantation (SCT).

Heike Pfeifer, Barbara Wassmann, Andreas Käbisch, Michael Lübbert, MD, PhD, Lothar Leimer, MD, Aristoteles Giagounidis, Dieter Hoelzer, MD, PhD, Oliver G. Ottmann, MD

Blood (2009) 114 (22): 2042.

https://doi.org/10.1182/blood.V114.22.2042.2042

Published: 2009

Journal Articles

Gene Expression Profiling Identifies IGFBP7 as a BAALC Co-Expressed Gene with a Functional Role in Acute Leukemia.

Sandra Heesch, MS, Cornelia Schlee, MS, Martin Neumann, Andrea Stroux, Andrea Kühnl, Stefan Schwartz, Dr., Torsten Haferlach, MD, Nicola Goekbuget, Dieter Hoelzer, MD, PhD, Wolf-Karsten Hofmann, Eckhard Thiel, MD, PhD, Claudia D Baldus, MD

Blood (2009) 114 (22): 2629.

https://doi.org/10.1182/blood.V114.22.2629.2629

Published: 2009

Journal Articles

New Definition of Treatment Response in Adult Acute Lymphoblastic Leukemia (ALL): Use of Molecular Markers for Minimal Residual Disease (MRD).

Nicola Goekbuget, MD, Monika Brueggemann, MD, Renate Arnold, MD, Claus-Rainer Bartram, PhD, Rainer Fietkau, MD, Mathias Freund, MD, Arnold Ganser, MD, Michael Kneba, MD, PhD, Thomas Lipp, MD, Wolf-Dieter Ludwig, MD, Georg Maschmeyer, MD, Dorle Messerer, Thorsten Raff, MD, Harald Rieder, MD, Eckhard Thiel, Dieter Hoelzer, MD, PhD

Blood (2009) 114 (22): 90.

https://doi.org/10.1182/blood.V114.22.90.90

Published: 2009

Journal Articles

Relevance of the Hematopoietic Cell Transplantation-Specific Comorbidity Index (HCT-CI) On Non-Relapse Related Mortality (NRM) in Patients with Acute Lymphoblastic Leukemia (ALL) Receiving Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in First Complete Remission: Results From the GMALL Study Group.

Matthias Stelljes, MD, Mareike David, Renate Arnold, MD, Dietrich W Beelen, MD, Wolfgang A Bethge, MD, Martin Bornhäuser, MD, Jolanta Dengler, MD, Juergen Finke, MD, Hans J Kolb, MD, Karin Kolbe, MD, Nicolaus Kröger, MD, Dietger Niederwieser, MD, Wolf Rösler, MD, Rainer Schwerdtfeger, MD, Joachim Kienast, MD, Nicola Goekbuget, MD, Dieter Hoelzer, MD, PhD

Blood (2009) 114 (22): 3352.

https://doi.org/10.1182/blood.V114.22.3352.3352

Published: 2009

Journal Articles

Successful Subtype Oriented Treatment Strategies in Adult T-All; Results of 744 Patients Treated in Three Consecutive GMALL Studies.

Blood (2009) 114 (22): 324.

https://doi.org/10.1182/blood.V114.22.324.324

Published: 2009

Journal Articles

Bendamustine Plus Rituximab Is Superior in Respect of Progression Free Survival and CR Rate When Compared to CHOP Plus Rituximab as First-Line Treatment of Patients with Advanced Follicular, Indolent, and Mantle Cell Lymphomas: Final Results of a Randomized Phase III Study of the StiL (Study Group Indolent Lymphomas, Germany).

Mathias J Rummel, MD, PhD, Norbert Niederle, Georg Maschmeyer, Andre Banat, MD, MBA, Ulrich von Gruenhagen, MD, Christoph Losem, Gerhard Heil, Manfred Welslau, Christina Balser, Ulrich Kaiser, Harald Ballo, Eckhart Weidmann, Heinz A Duerk, Dorothea Kofahl-Krause, Fritz Roller, Juergen Barth, Dieter Hoelzer, MD, PhD, Axel Hinke, Wolfram Brugger

Blood (2009) 114 (22): 405.

https://doi.org/10.1182/blood.V114.22.405.405

Published: 2009

Journal Articles

PEG-Asparaginase in Adult Acute Lymphoblastic Leukemia (ALL): Efficacy and Feasibility Analysis with Increasing Dose Levels

Nicola Goekbuget, MD, Anja Baumann, MD, Joachim Beck, MD, Joachim Boos, MD, PhD, Monika Brueggemann, MD, PhD, Helmut Diedrich, MD, Andreas Hüttmann, MD, Lothar Leimer, MD, Thomas Lipp, MD, Ralph Naumann, MD, PhD, Martin Mohren, MD, Albrecht Reichle, MD, PhD, Kerstin Schäfer-Eckart, MD, Marc Schmalzing, MD, Mathias Schmid, MD, PhD, Norbert Schmitz, MD, PhD, Theis Therwey, MD, Dieter Hoelzer, MD, PhD

Blood (2008) 112 (11): 302.

https://doi.org/10.1182/blood.V112.11.302.302

Published: 2008

Journal Articles

Wilms Tumor 1 Gene Mutations in Adult Acute T-Lymphoblastic Leukemia

Sandra Heesch, MS, Nicola Goekbuget, MD, Jutta Ortiz Tanchez, Cornelia Schlee, MS, Stefan Schwartz, Thomas Burmeister, MD, Dieter Hoelzer, MD, PhD, Eckhard Thiel, MD, PhD, Wolf K Hofmann, MD, Claudia D Baldus, MD

Blood (2008) 112 (11): 2516.

https://doi.org/10.1182/blood.V112.11.2516.2516

Published: 2008

Journal Articles

Epigenetic Dysregulation of GATA1 but Not Downstream Notch Effectors is Involved in MDS Dyserythropoiesis.

Olaf Joachim Hopfer, MD, Martina Komor, PhD, Claudia Freitag, Maximilian Mossner, Dieter Hoelzer, MD, PhD, Eckhard Thiel, MD, PhD, Wolf-Karsten Hofmann, MD, PhD

Blood (2008) 112 (11): 1652.

https://doi.org/10.1182/blood.V112.11.1652.1652

Published: 2008

Journal Articles

First European Chemotherapy Schedule for Elderly Patients with Acute Lymphoblastic Leukemia: Promising Remission Rate and Feasible Moderate Dose Intensity Consolidation

Nicola Goekbuget, MD, Thibaut Leguay, MD, Mathilde Hunault, MD, Chadi Al-Nawakil, MD, Patrice Chevallier, MD, Herve Dombret, MD, Gisela Fritsch, MD, Albert Oriol, MD, Josep Maria Ribera, MD, Philippe Rousselot, MD, Juan Manuel Sancho, MD, Dieter Hoelzer, MD, PhD

Blood (2008) 112 (11): 304.

https://doi.org/10.1182/blood.V112.11.304.304

Published: 2008

Journal Articles

Dasatinib (Sprycel®) and Chemotherapy for First-Line Treatment in Elderly Patients with De Novo Philadelphia Positive ALL: Results of the First 22 Patients Included in the EWALL-Ph-01 Trial (on Behalf of the European Working Group on Adult ALL (EWALL))

Blood (2008) 112 (11): 2920.

https://doi.org/10.1182/blood.V112.11.2920.2920

Published: 2008

NARROW

Nilotinib (Tasigna ® ) and Low Intensity Chemotherapy for First-Line Treatment of Elderly Patients with BCR-ABL1- Positive Acute Lymphoblastic Leukemia: Final Results of a Prospective Multicenter Trial (EWALL-PH02)

Comorbidities Are Frequent in Older Patients with De Novo Acute Lymphoblastic Leukemia (ALL) and Correlate with Induction Mortality: Analysis of More Than 1200 Patients from GMALL Data Bases

CD20 Expression and Response to Rituximab Treatment in B-Cell Precursor Lymphoblastic Leukemia - Results of the GMALL 08/2013 Trial

Monitoring of the Clonal Architecture of B-Cell Precursor ALL during Induction Chemoimmunotherapy

Evaluation of Minimal Residual Disease (MRD) and MRD-Based Treatment Decisions in Ph/BCR-ABL Negative Adult Acute Lymphoblastic Leukemia (ALL): Experience from the German Multicenter Study Group for Adult ALL (GMALL)

Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia

The Role of Microrna-196a-1 and Microrna-196b in Acute T-Lymphoblastic Leukemia and Acute Myeloid Leukemia.

Overexpression of BAALC Indicates Drug Resistance and Inferior Survival in Adult B-Precursor Acute Lymphoblastic Leukemia.

Serial Analysis of BCR-ABL Kinase Domain Mutations Prior to and During Imatinib Treatment for Newly Diagnosed and Recurrent BCR-ABL Positive Acute Lymphoblastic Leukemia.

Imatinib and Interferon-Alpha Maintenance Therapy for Patients with Philadelphia-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Ineligible for Allogeneic Stem Cell Transplantation (SCT).

Gene Expression Profiling Identifies IGFBP7 as a BAALC Co-Expressed Gene with a Functional Role in Acute Leukemia.

New Definition of Treatment Response in Adult Acute Lymphoblastic Leukemia (ALL): Use of Molecular Markers for Minimal Residual Disease (MRD).

Successful Subtype Oriented Treatment Strategies in Adult T-All; Results of 744 Patients Treated in Three Consecutive GMALL Studies.

PEG-Asparaginase in Adult Acute Lymphoblastic Leukemia (ALL): Efficacy and Feasibility Analysis with Increasing Dose Levels

Wilms Tumor 1 Gene Mutations in Adult Acute T-Lymphoblastic Leukemia

Epigenetic Dysregulation of GATA1 but Not Downstream Notch Effectors is Involved in MDS Dyserythropoiesis.

First European Chemotherapy Schedule for Elderly Patients with Acute Lymphoblastic Leukemia: Promising Remission Rate and Feasible Moderate Dose Intensity Consolidation

Dasatinib (Sprycel®) and Chemotherapy for First-Line Treatment in Elderly Patients with De Novo Philadelphia Positive ALL: Results of the First 22 Patients Included in the EWALL-Ph-01 Trial (on Behalf of the European Working Group on Adult ALL (EWALL))

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American Society of Hematology

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