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Journal Articles

2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party

Michael Heuser, Sylvie D. Freeman, Gert J. Ossenkoppele, Francesco Buccisano, Christopher S. Hourigan, Lok Lam Ngai, Jesse M. Tettero, Costa Bachas, Constance Baer, Marie-Christine Béné, Veit Bücklein, Anna Czyz, Barbara Denys, Richard Dillon, Michaela Feuring-Buske, Monica L. Guzman, Torsten Haferlach, Lina Han, Julia K. Herzig, Jeffrey L. Jorgensen, Wolfgang Kern, Marina Y. Konopleva, Francis Lacombe, Marta Libura, Agata Majchrzak, Luca Maurillo, Yishai Ofran, Jan Philippe, Adriana Plesa, Claude Preudhomme, Farhad Ravandi, Christophe Roumier, Marion Subklewe, Felicitas Thol, Arjan A. van de Loosdrecht, Bert A. van der Reijden, Adriano Venditti, Agnieszka Wierzbowska, Peter J. M. Valk, Brent L. Wood, Roland B. Walter, Christian Thiede, Konstanze Döhner, Gail J. Roboz, Jacqueline Cloos
Journal: Blood
Blood (2021) 138 (26): 2753–2767.
https://doi.org/10.1182/blood.2021013626
Published: 2021
Includes: Supplemental data
Journal Articles

Unsupervised Flow Cytometry Analysis: Application to Minimal Residual Disease Detection in a Cohort of 40 Acute Myeloblastic Leukemia Patients with Molecular Markers

Nicolas Lechevalier, PharmD, Jean-Philippe Vial, MD, Francis Lacombe, MDPhD, Pierre-Yves Dumas, MDPhD, Audrey Bidet, PharmD, Thibaut Leguay, MD, Francois Vergez, DVM, PhD, Arnaud Pigneux, MD PhD, Marie C Béné, PharmSciD, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-141199
Published: 2020
Journal Articles

Flowsom: An R-Based Evaluation Strategy for Flow Cytometry-Based Measurable Residual Disease (MRD) Diagnostics in Acute Myeloid Leukemia (AML)

Veit Bücklein, MD, Alexandra Stein, Benjamin Tast, PhD, Thomas Koehnke, MD, Karsten Spiekermann, MD, Francis Lacombe, MD PhD, Marion Subklewe, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4656.
https://doi.org/10.1182/blood-2019-129866
Published: 2019
Journal Articles

Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party

Clinical Trials & Observations
Gerrit J. Schuurhuis, Michael Heuser, Sylvie Freeman, Marie-Christine Béné, Francesco Buccisano, Jacqueline Cloos, David Grimwade, Torsten Haferlach, Robert K. Hills, Christopher S. Hourigan, Jeffrey L. Jorgensen, Wolfgang Kern, Francis Lacombe, Luca Maurillo, Claude Preudhomme, Bert A. van der Reijden, Christian Thiede, Adriano Venditti, Paresh Vyas, Brent L. Wood, Roland B. Walter, Konstanze Döhner, Gail J. Roboz, Gert J. Ossenkoppele
Journal: Blood
Blood (2018) 131 (12): 1275–1291.
https://doi.org/10.1182/blood-2017-09-801498
Published: 2018
Includes: Supplemental data
Journal Articles

New Concepts of Flow Cytometry Analysis in Oncohematology: Application to Diagnosis and Follow up (Minimal Residual Disease) in AML, ALL and MDS

Francis Lacombe, MD PhD, Benoït Dupont, Nicolas Lechevalier, PharmD, Jean-Philippe Vial, MD, Arnaud Pigneux, MD PhD, Marie C Bene, PharmSciD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1421.
https://doi.org/10.1182/blood.V130.Suppl_1.1421.1421
Published: 2017
Journal Articles

Assessment Of Minimal Residual Disease In Acute Myeloblastic Leukemia In Multiparameter Flow Cytometry

Francis Lacombe, Kaoutar Allou, Christine Arnoulet, Pharm. D., Lydia Campos, MD, PhD, Adrienne de Labarthe, Florent Dumezy, MD, Jean Feuillard, Franck Genevieve, MD, PhD, Estelle Guerin, Julien Guy, Hélène Jouault, Pascale Lepelley, MD, Marc Maynadie, MD, PhD, Francoise Solly, Orianne Wagner Ballon, Claude Preudhomme, Andre Baruchel, MD, PhD, Herve Dombret, MD, PhD, Norbert Ifrah, MD, Marie C. Béné, PharmSciD, PhD
Journal: Blood
Blood (2013) 122 (21): 2613.
https://doi.org/10.1182/blood.V122.21.2613.2613
Published: 2013
Journal Articles

Flow Cytometry Thresholds of Myeloperoxidase Detection to Discriminate Between Acute Lymphoblastic or Myeloblastic Leukemia

Julien Guy, Iléana Antony-Debré, Isabelle Arnoux, Chantal Fossat, Emmanuel Benayoun, Magali Le Garff-Tavernier, Anna Raimbault, Michèle Imbert, MD, Marc Maynadie, MD, PhD, Francis Lacombe, Marie C Béné, Orianne Wagner-Ballon
Journal: Blood
Blood (2012) 120 (21): 1450.
https://doi.org/10.1182/blood.V120.21.1450.1450
Published: 2012
Journal Articles

Assessment of Peripheral Blood (PB) Blast Decrease Rate by Multiparameter Flow Cytometry: A New Prognostic Factor in Acute Myeloblastic Leukaemia (AML). A Goelams Study.

Francis Lacombe, MD, PhD, Christine Arnoulet, MD,PhD, Marc Maynadie, MD,PhD, Arnaud Pigneux, MD,PhD, Norbert Vey, MD, Olivier Casasnovas, MD, Francis Witz, MD, Marie C. Bene, PharmsSciD,PhD
Journal: Blood
Blood (2006) 108 (11): 1892.
https://doi.org/10.1182/blood.V108.11.1892.1892
Published: 2006
Journal Articles

Triptolide Cooperates with Cytarabine To Induce Apoptosis in Acute Myeloid Leukemia.

Arnaud Pigneux, MD, Maïalen Uhalde, PhD, François X. Mahon, MD,PhD, Francis Lacombe, PhD, Vincent Praloran, MD,PhD, Noel-Jean Milpied, MD, Francis Belloc, PhD
Journal: Blood
Blood (2006) 108 (11): 1902.
https://doi.org/10.1182/blood.V108.11.1902.1902
Published: 2006
Journal Articles

Dendritic Cells Recovery and Chimerism after Reduced Intensity Hematopoietic Stem Cell Transplantation.

Reza Tabrizi, MD, Francis Belloc, PhD, Xavier Lafarge, Virginie Perreau, Krimo Bouabdallah, MD, Gerald Marit, MD, Fontanet Bijou, MD, Thibaut Leguay, MD, Francis Lacombe, Arnaud Pigneux, MD, Cyril Melot, François Comeau, Jean-Michel Boiron, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 5341.
https://doi.org/10.1182/blood.V106.11.5341.5341
Published: 2005
Journal Articles

Proteasome Inhibition Sensitizes Leukemic Cells to Anthracyclin-Induced Apoptosis by Increasing the Expression of Bim and Bax Pro-Apoptotic Proteins.

Arnaud Pigneux, MD, François X. Mahon, MD, PhD, François Moreau-Gaudry, PhD, Marie L. Néré, Francis Lacombe, MD, PhD, Josy Reiffers, MD, Vincent Praloran, MD, Francis Belloc, PhD
Journal: Blood
Blood (2005) 106 (11): 2487.
https://doi.org/10.1182/blood.V106.11.2487.2487
Published: 2005
Journal Articles

Bim-EL, Is Sensitive to Proteasome Degradation and Contributes to Inducing Apoptosis after In Vitro Imatinib Mesylate Treatment of BCR-ABL Positive Cells.

Francis Belloc, PhD, Catherine Boyer, Francis Lacombe, MD, PhD, Vincent Praloran, MD, François-Xavier Mahon, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 4676.
https://doi.org/10.1182/blood.V104.11.4676.4676
Published: 2004