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Journal Articles

Platelet Mitochondria Calcium Uniporter Regulates ITAM-Dependent Platelet Activation and Signaling

Abigail Ajanel Gomez, Frederik Denorme, Irina Portier, Mia Kowalczyk, Sradha Rameshbhatt, Yasuhiro Kosaka, Robert A. Campbell

Blood (2023) 142 (Supplement 1): 1187.

https://doi.org/10.1182/blood-2023-189538

Published: 2023

Journal Articles

Mitochondrial Fission Protein Drp1 Regulates Platelet Function

Shancy Jacob, Marina Tistao, Abigail Ajanel Gomez, Frederik Denorme, Yasuhiro Kosaka, Bhanu Kanth Manne, Li Guo, Robert A. Campbell, Matthew T. Rondina, Jesse W Rowley

Blood (2023) 142 (Supplement 1): 1201.

https://doi.org/10.1182/blood-2023-187556

Published: 2023

Journal Articles

Platelets net neutrophils during ALI

Frederik Denorme, Robert A. Campbell

Blood (2023) 142 (17): 1409–1410.

https://doi.org/10.1182/blood.2023021641

Published: 2023

Journal Articles

MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis

Bhanu Kanth Manne, Robert A. Campbell, Seema Bhatlekar, Abigail Ajanel, Frederik Denorme, Irina Portier, Elizabeth A. Middleton, Neal D. Tolley, Yasuhiro Kosaka, Emilie Montenont, Li Guo, Jesse W. Rowley, Paul F. Bray, Shancy Jacob, Rikiro Fukanaga, Christopher Proud, Andrew S. Weyrich, Matthew T. Rondina

Blood (2022) 140 (23): 2477–2489.

https://doi.org/10.1182/blood.2022015568

Published: 2022

Includes: Supplemental data

Journal Articles

The Common Racially Diverse Human PAR4 Variant Thr120 Causes Worse Outcomes in a Mouse Stroke Model Via Platelet-Mediated NET Formation: Prevention By P-Selectin Blockade

Frederik Denorme, Irina Portier, Michelle L. Stoller, Emilia A Tugolukova, Emilie Montenont, Seema Bhatlekar, Mark Cody, John L Rustad, Paul F. Bray, Robert A. Campbell

Blood (2022) 140 (Supplement 1): 5512–5513.

https://doi.org/10.1182/blood-2022-159790

Published: 2022

Journal Articles

Mitofusin2 (MFN2) Preserves Mitochondrial Integrity and Function in Megakaryocytes and Platelets

Blood (2021) 138 (Supplement 1): 3137.

https://doi.org/10.1182/blood-2021-154329

Published: 2021

Journal Articles

The mTOR Pathway in Platelets Contributes to the Pathophysiology of Experimental Cerebral Malaria

Irina Portier, Frederik Denorme, Kimberly A Queisser, Yasuhiro Kosaka, Aaron C Petrey, Guy A Zimmerman, Robert A. Campbell, Matthew T. Rondina

Blood (2021) 138 (Supplement 1): 580.

https://doi.org/10.1182/blood-2021-152335

Published: 2021

Journal Articles

Platelet-Mediated NET Formation Exacerbates Ischemic Stroke Brain Injury

Frederik Denorme, Irina Portier, Mark Cody, Ramesh Grandhi, Matthew D Neal, Jennifer J Majersik, Christian Yost, Robert A. Campbell

Blood (2021) 138 (Supplement 1): 437.

https://doi.org/10.1182/blood-2021-151423

Published: 2021

Journal Articles

Placental HTRA1 cleaves α 1 -antitrypsin to generate a NET-inhibitory peptide

Robert A. Campbell, Heather D. Campbell, J. Samuel Bircher, Claudia Valeria de Araujo, Frederik Denorme, Jacob L. Crandell, John L. Rustad, Josh Monts, Mark J. Cody, Yasuhiro Kosaka, Christian C. Yost

Blood (2021) 138 (11): 977–988.

https://doi.org/10.1182/blood.2020009021

Published: 2021

Includes: Supplemental data

Journal Articles

Platelet MHC class I mediates CD8 + T-cell suppression during sepsis

Blood (2021) 138 (5): 401–416.

https://doi.org/10.1182/blood.2020008958

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Blockade of Human PAR4 in Novel Humanized Mouse Strains Supports PAR4 As a Potential Target in Stroke: Ex Vivo Demonstration of Platelet Hyperreactivity of the Thr120 Variant

Robert A. Campbell, PhD, Michelle L. Stoller, PhD, Frederik Denorme, PhD, Bhanu Kanth Manne, PhD, Seema Bhatlekar, PhD, Emilia A Tugolukova, B.S., Paul F. Bray, MD

Blood (2020) 136 (Supplement 1): 12.

https://doi.org/10.1182/blood-2020-136178

Published: 2020

Journal Articles

Platelet gene expression and function in patients with COVID-19

Bhanu Kanth Manne, Frederik Denorme, Elizabeth A. Middleton, Irina Portier, Jesse W. Rowley, Chris Stubben, Aaron C. Petrey, Neal D. Tolley, Li Guo, Mark Cody, Andrew S. Weyrich, Christian C. Yost, Matthew T. Rondina, Robert A. Campbell

Blood (2020) 136 (11): 1317–1329.

https://doi.org/10.1182/blood.2020007214

Published: 2020

Includes: Supplemental data

Journal Articles

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

Blood (2020) 136 (10): 1169–1179.

https://doi.org/10.1182/blood.2020007008

Published: 2020

Includes: Supplemental data

Journal Articles

Platelet necrosis mediates ischemic stroke outcome in mice

Frederik Denorme, Bhanu Kanth Manne, Irina Portier, Alicia S. Eustes, Yasuhiro Kosaka, Benjamin T. Kile, Matthew T. Rondina, Robert A. Campbell

Blood (2020) 135 (6): 429–440.

https://doi.org/10.1182/blood.2019002124

Published: 2020

Includes: Supplemental data

Journal Articles

Cyclophilin D Mediated Platelet Necrosis Regulates Ischemic Stroke Outcomes in Mice

Frederik Denorme, PhD, Bhanu Kanth Manne, PhD, Yasuhiro Kosaka, PhD, Benjamin Kile, PhD, Matthew T. Rondina, MD, Robert A. Campbell, PhD

Blood (2019) 134 (Supplement_1): 3620.

https://doi.org/10.1182/blood-2019-123839

Published: 2019

Journal Articles

ADAMTS13-mediated thrombolysis of t-PA–resistant occlusions in ischemic stroke in mice

Frederik Denorme, Friederike Langhauser, Linda Desender, Aline Vandenbulcke, Hanspeter Rottensteiner, Barbara Plaimauer, Olivier François, Tommy Andersson, Hans Deckmyn, Friedrich Scheiflinger, Christoph Kleinschnitz, Karen Vanhoorelbeke, Simon F. De Meyer

Blood (2016) 127 (19): 2337–2345.

https://doi.org/10.1182/blood-2015-08-662650

Published: 2016

Includes: Supplemental data

Journal Articles

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice

Sebastien Verhenne, Frederik Denorme, Sarah Libbrecht, Aline Vandenbulcke, Inge Pareyn, Hans Deckmyn, Antoon Lambrecht, Bernhard Nieswandt, Christoph Kleinschnitz, Karen Vanhoorelbeke, Simon F. De Meyer

Blood (2015) 126 (14): 1715–1722.

https://doi.org/10.1182/blood-2015-03-632901

Published: 2015

Includes: Supplemental data

Journal Articles

Innovative thrombolytic strategy using a heterodimer diabody against TAFI and PAI-1 in mouse models of thrombosis and stroke

Tine Wyseure, Marina Rubio, Frederik Denorme, Sara Martinez de Lizarrondo, Miet Peeters, Ann Gils, Simon F. De Meyer, Denis Vivien, Paul J. Declerck

Blood (2015) 125 (8): 1325–1332.

https://doi.org/10.1182/blood-2014-07-588319

Published: 2015

Includes: Supplemental data

NARROW

Platelet Mitochondria Calcium Uniporter Regulates ITAM-Dependent Platelet Activation and Signaling

Mitochondrial Fission Protein Drp1 Regulates Platelet Function

Platelets net neutrophils during ALI

MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis

The Common Racially Diverse Human PAR4 Variant Thr120 Causes Worse Outcomes in a Mouse Stroke Model Via Platelet-Mediated NET Formation: Prevention By P-Selectin Blockade

Mitofusin2 (MFN2) Preserves Mitochondrial Integrity and Function in Megakaryocytes and Platelets

The mTOR Pathway in Platelets Contributes to the Pathophysiology of Experimental Cerebral Malaria

Platelet-Mediated NET Formation Exacerbates Ischemic Stroke Brain Injury

Placental HTRA1 cleaves α 1 -antitrypsin to generate a NET-inhibitory peptide

Platelet MHC class I mediates CD8 + T-cell suppression during sepsis

Blockade of Human PAR4 in Novel Humanized Mouse Strains Supports PAR4 As a Potential Target in Stroke: Ex Vivo Demonstration of Platelet Hyperreactivity of the Thr120 Variant

Platelet gene expression and function in patients with COVID-19

Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome

Platelet necrosis mediates ischemic stroke outcome in mice

Cyclophilin D Mediated Platelet Necrosis Regulates Ischemic Stroke Outcomes in Mice

ADAMTS13-mediated thrombolysis of t-PA–resistant occlusions in ischemic stroke in mice

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice

Innovative thrombolytic strategy using a heterodimer diabody against TAFI and PAI-1 in mouse models of thrombosis and stroke

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American Society of Hematology

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ASH Publications

American Society of Hematology

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