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Journal Articles

Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura

Clinical Trials & Observations
Elien Roose, An-Sofie Schelpe, Edwige Tellier, György Sinkovits, Bérangère S. Joly, Charlotte Dekimpe, Gilles Kaplanski, Maelle Le Besnerais, Ilaria Mancini, Tanja Falter, Charis Von Auer, Hendrik B. Feys, Marienn Reti, Heidi Rossmann, Aline Vandenbulcke, Inge Pareyn, Jan Voorberg, Andreas Greinacher, Ygal Benhamou, Hans Deckmyn, Rob Fijnheer, Zoltan Prohászka, Flora Peyvandi, Bernhard Lämmle, Paul Coppo, Simon F. De Meyer, Agnès Veyradier, Karen Vanhoorelbeke
Journal: Blood
Blood (2020) 136 (3): 353–361.
https://doi.org/10.1182/blood.2019004221
Published: 2020
Includes: Supplemental data
Journal Articles

Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology

Elien Roose, PhD, An-Sofie Schelpe, Edwige Tellier, György Sinkovits, MD, Gilles Kaplanski, MD, Maelle Le Besnerais, Ilaria Mancini, PhD, Nele Vandeputte, Aline Vandenbulcke, Inge Pareyn, J. J. Voorberg, PhD, Andreas Greinacher, MD, Ygal Benhamou, MD, Hans Deckmyn, PhD, Rob FIjnheer, MD, Zoltan Prohászka, MD Prof, Flora Peyvandi, MD PhD, Paul Coppo, MD PhD, Simon F De Meyer, PhD, Agnès Veyradier, Sr., MD PhD, Karen Vanhoorelbeke, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 222.
https://doi.org/10.1182/blood-2018-99-113762
Published: 2018
Journal Articles

N -acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura

Claudia Tersteeg, Jan Roodt, Walter J. Van Rensburg, Charlotte Dekimpe, Nele Vandeputte, Inge Pareyn, Aline Vandenbulcke, Barbara Plaimauer, Seb Lamprecht, Hans Deckmyn, José A. Lopez, Simon F. De Meyer, Karen Vanhoorelbeke
Journal: Blood
Blood (2017) 129 (8): 1030–1038.
https://doi.org/10.1182/blood-2016-09-738856
Published: 2017
Includes: Supplemental data
Journal Articles

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice

Sebastien Verhenne, Frederik Denorme, Sarah Libbrecht, Aline Vandenbulcke, Inge Pareyn, Hans Deckmyn, Antoon Lambrecht, Bernhard Nieswandt, Christoph Kleinschnitz, Karen Vanhoorelbeke, Simon F. De Meyer
Journal: Blood
Blood (2015) 126 (14): 1715–1722.
https://doi.org/10.1182/blood-2015-03-632901
Published: 2015
Includes: Supplemental data
Journal Articles

Inhibition of von Willebrand factor–platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons

Brief Report
Hendrik B. Feys, Jan Roodt, Nele Vandeputte, Inge Pareyn, Harald Mottl, Sam Hou, Seb Lamprecht, Walter J. Van Rensburg, Hans Deckmyn, Karen Vanhoorelbeke
Journal: Blood
Blood (2012) 120 (17): 3611–3614.
https://doi.org/10.1182/blood-2012-04-421248
Published: 2012
Includes: Supplemental data
Journal Articles

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon ( Papio ursinus )

Hendrik B. Feys, Jan Roodt, Nele Vandeputte, Inge Pareyn, Seb Lamprecht, Walter J. van Rensburg, Patricia J. Anderson, Ulrich Budde, Vernon J. Louw, Philip N. Badenhorst, Hans Deckmyn, Karen Vanhoorelbeke
Journal: Blood
Blood (2010) 116 (12): 2005–2010.
https://doi.org/10.1182/blood-2010-04-280479
Published: 2010
Includes: Supplemental data
Journal Articles

Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura

Brief Report
Hendrik B. Feys, Inge Pareyn, Renee Vancraenenbroeck, Marc De Maeyer, Hans Deckmyn, Chris Van Geet, Karen Vanhoorelbeke
Journal: Blood
Blood (2009) 114 (21): 4749–4752.
https://doi.org/10.1182/blood-2009-07-230615
Published: 2009
Journal Articles

Phenotypic correction of von Willebrand disease type 3 blood-derived endothelial cells with lentiviral vectors expressing von Willebrand factor

Simon F. De Meyer, Karen Vanhoorelbeke, Marinee K. Chuah, Inge Pareyn, Veerle Gillijns, Robert P. Hebbel, Désiré Collen, Hans Deckmyn, Thierry VandenDriessche
Journal: Blood
Blood (2006) 107 (12): 4728–4736.
https://doi.org/10.1182/blood-2005-09-3605
Published: 2006
Journal Articles

Phenotypic Correction of von Willebrand Disease Type 3 Blood-Derived Endothelial Cells with Lentiviral Vectors Expressing von Willebrand Factor.

Simon F. De Meyer, Karen Vanhoorelbeke, PhD, Marinee K. Chuah, PhD, Inge Pareyn, Veerle Gillijns, Robert P. Hebbel, MD, Hans Deckmyn, PhD, Thierry Vandendriessche, PhD
Journal: Blood
Blood (2005) 106 (11): 5522.
https://doi.org/10.1182/blood.V106.11.5522.5522
Published: 2005
Journal Articles

Newly Developed ADAMTS13 Antigen Assay Reveals Marked Ethnic Differences and Depletion in Acquired Thrombotic Thrombocytopenic Purpura.

Hendrik B. Feys, Mr, Fang Liu, MD, Ningzheng Dong, MD, PhD, Inge Pareyn, Stephan Vauterin, Nele Vandeputte, Changgeng Ruan, MD, PhD, Deckmyn Hans, PhD, Vanhoorelbeke Karen, PhD
Journal: Blood
Blood (2005) 106 (11): 1251.
https://doi.org/10.1182/blood.V106.11.1251.1251
Published: 2005