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Gilles Kaplanski
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Journal Articles

Reduction of mortality, cardiac damage, and cerebral damage by IL-1 inhibition in a murine model of TTP

Romain Muller, Raphaël Cauchois, Marie Lagarde, Sandrine Roffino, Cécile Genovesio, Samantha Fernandez, Guillaume Hache, Benjamin Guillet, Yéter Kara, Marion Marlinge, Peter Lenting, Pascale Poullin, Françoise Dignat-George, Edwige Tellier, Gilles Kaplanski
Journal: Blood
Blood (2024) 143 (26): 2791–2803.
https://doi.org/10.1182/blood.2023021974
Published: 2024
Includes: Supplemental data
Journal Articles

COVID-19 as a potential trigger of complement-mediated atypical HUS

Clinical Trials & Observations
Carine El Sissy, Antonin Saldman, Gilbert Zanetta, Paula Vieira Martins, Coralie Poulain, Raphaël Cauchois, Gilles Kaplanski, Jean-Pierre Venetz, Mickaël Bobot, Hélène Dobosziewicz, Laurent Daniel, Marie Koubi, Salima Sadallah, Samuel Rotman, Christiane Mousson, Manuel Pascual, Véronique Frémeaux-Bacchi, Fadi Fakhouri
Journal: Blood
Blood (2021) 138 (18): 1777–1782.
https://doi.org/10.1182/blood.2021012752
Published: 2021
Includes: Supplemental data
Journal Articles

Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect

Clinical Trials & Observations
Julien Carvelli, Christelle Piperoglou, Catherine Farnarier, Frédéric Vely, Karin Mazodier, Sandra Audonnet, Patrick Nitschke, Christine Bole-Feysot, Mohamed Boucekine, Audrey Cambon, Mohamed Hamidou, Jean-Robert Harle, Geneviève de Saint Basile, Gilles Kaplanski
Journal: Blood
Blood (2020) 136 (5): 542–552.
https://doi.org/10.1182/blood.2019003664
Published: 2020
Includes: Supplemental data
Journal Articles

Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura

Clinical Trials & Observations
Elien Roose, An-Sofie Schelpe, Edwige Tellier, György Sinkovits, Bérangère S. Joly, Charlotte Dekimpe, Gilles Kaplanski, Maelle Le Besnerais, Ilaria Mancini, Tanja Falter, Charis Von Auer, Hendrik B. Feys, Marienn Reti, Heidi Rossmann, Aline Vandenbulcke, Inge Pareyn, Jan Voorberg, Andreas Greinacher, Ygal Benhamou, Hans Deckmyn, Rob Fijnheer, Zoltan Prohászka, Flora Peyvandi, Bernhard Lämmle, Paul Coppo, Simon F. De Meyer, Agnès Veyradier, Karen Vanhoorelbeke
Journal: Blood
Blood (2020) 136 (3): 353–361.
https://doi.org/10.1182/blood.2019004221
Published: 2020
Includes: Supplemental data
Journal Articles

Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology

Elien Roose, PhD, An-Sofie Schelpe, Edwige Tellier, György Sinkovits, MD, Gilles Kaplanski, MD, Maelle Le Besnerais, Ilaria Mancini, PhD, Nele Vandeputte, Aline Vandenbulcke, Inge Pareyn, J. J. Voorberg, PhD, Andreas Greinacher, MD, Ygal Benhamou, MD, Hans Deckmyn, PhD, Rob FIjnheer, MD, Zoltan Prohászka, MD Prof, Flora Peyvandi, MD PhD, Paul Coppo, MD PhD, Simon F De Meyer, PhD, Agnès Veyradier, Sr., MD PhD, Karen Vanhoorelbeke, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 222.
https://doi.org/10.1182/blood-2018-99-113762
Published: 2018
Journal Articles

Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

Clinical Trials & Observations
Karin Mazodier, Valérie Marin, Daniela Novick, Catherine Farnarier, Stéphane Robitail, Nicolas Schleinitz, Véronique Veit, Pascale Paul, Menachem Rubinstein, Charles A. Dinarello, Jean-Robert Harlé, Gilles Kaplanski
Journal: Blood
Blood (2005) 106 (10): 3483–3489.
https://doi.org/10.1182/blood-2005-05-1980
Published: 2005
Journal Articles

Efficiency of curative and prophylactic treatment with rituximab in ADAMTS13-deficient thrombotic thrombocytopenic purpura: a study of 11 cases

Clinical Trials & Observations
Fadi Fakhouri, Jean-Paul Vernant, Agnès Veyradier, Martine Wolf, Gilles Kaplanski, Raynald Binaut, Manfred Rieger, Friedrich Scheiflinger, Pascale Poullin, Benjamin Deroure, Richard Delarue, Philippe Lesavre, Philippe Vanhille, Olivier Hermine, Giuseppe Remuzzi, Jean-Pierre Grünfeld
Journal: Blood
Blood (2005) 106 (6): 1932–1937.
https://doi.org/10.1182/blood-2005-03-0848
Published: 2005
Journal Articles

The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment

Valérie Marin, Catherine Farnarier, Sandra Grès, Solange Kaplanski, Michael S.-S. Su, Charles A. Dinarello, Gilles Kaplanski
Journal: Blood
Blood (2001) 98 (3): 667–673.
https://doi.org/10.1182/blood.V98.3.667
Published: 2001
Journal Articles

Thrombin-Activated Human Endothelial Cells Support Monocyte Adhesion In Vitro Following Expression of Intercellular Adhesion Molecule-1 (ICAM-1; CD54) and Vascular Cell Adhesion Molecule-1 (VCAM-1; CD106)

Gilles Kaplanski, Valérie Marin, Martine Fabrigoule, Vera Boulay, Anne-Marie Benoliel, Pierre Bongrand, Solange Kaplanski, Catherine Farnarier
Journal: Blood
Blood (1998) 92 (4): 1259–1267.
https://doi.org/10.1182/blood.V92.4.1259
Published: 1998