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Journal Articles

Microvascular Stasis Inhibition By Hemopexin in the Townes Mouse Model of Sickle Cell Disease

Thomas Gentinetta, PhD, Gregory M. Vercellotti, MD, Chunsheng Chen, Julia Nguyen, Fuad Abdulla, Ping Zhang, PhD, Gregory J Kato, MD, Nathan Brinkman, PhD, Adrian Zuercher, PhD, John D Belcher, PhD

Blood (2020) 136 (Supplement 1): 9.

https://doi.org/10.1182/blood-2020-140236

Published: 2020

Journal Articles

Prevention of Heme-Induced Human Endothelial Cell Activation By Hemopexin in Vitro

Jacqueline Adam, PhD, Thomas Gentinetta, PhD, Svetlana Diditchenko, PhD, Alexander Schaub, PhD, Gregory J Kato, MD, Nathan Brinkman, PhD, Adrian Zuercher, PhD

Blood (2020) 136 (Supplement 1): 8.

https://doi.org/10.1182/blood-2020-140238

Published: 2020

Journal Articles

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

Solomon Johnson, MS, Victor R. Gordeuk, MD, Roberto Machado, MD, J Simon R Gibbs, Mariana Hildesheim, MS, Jane A. Little, MD, Gregory J Kato, MD, Mark T Gladwin, MD, Seyed Mehdi Nouraie, PhD MD

Blood (2020) 136 (Supplement 1): 59–60.

https://doi.org/10.1182/blood-2020-136393

Published: 2020

Journal Articles

Nrf2 Null Mice Are Deficient in CD169 + Macrophages, Associated with Impaired Erythroid Response and Delayed Recovery from Acute Blood Loss

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Mark A Ross, Samit Ghosh, Frances Weidert, MS, Grant C. Bullock, MD PhD, Solomon Fiifi Ofori-Acquah, Gregory J Kato, MD, Simon Watkins

Blood (2019) 134 (Supplement_1): 1038.

https://doi.org/10.1182/blood-2019-127295

Published: 2019

Journal Articles

A Prospective Phase II, Open-Label, Single-Arm, Multicenter Study to Assess the Efficacy and Safety of SEG101 (Crizanlizumab) in Sickle Cell Disease Patients with Priapism (SPARTAN)

Fuad A El Rassi, MD, Deepika S. Darbari, MD, Arthur Burnett, MD MBA, Jincy Paulose, MD, Dramane I Laine, Das Purkayastha, PhD, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 1007.

https://doi.org/10.1182/blood-2019-125790

Published: 2019

Journal Articles

Macrophage Hypercellularity Accompanies Erythroid Hyperplasia in Sickle Cell Mice and during Recovery from Blood Loss in Wild Type Mice

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Samit Ghosh, Frances Weidert, MS, Grant C. Bullock, MD PhD, Solomon Fiifi Ofori-Acquah, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 3528.

https://doi.org/10.1182/blood-2019-127224

Published: 2019

Journal Articles

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

Tirthadipa Pradhan, Prithu Sundd, PhD, Mark T Gladwin, MD, Satdarshan Pal Monga, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 3536.

https://doi.org/10.1182/blood-2019-131915

Published: 2019

Journal Articles

A Phase II Trial of Topical Sodium Nitrite in Patients with Sickle Cell Disease and Leg Ulcers

Shuo You, MD, Andrew Crouch, Ugochi Olivia Ogu, MD, Clemencia Solorzano, PharmD, Gracy Sebastian, NP, Markenya Mirander, Giacomo Vinces, D.O., Gregory J Kato, MD, Caterina P. Minniti, MD

Blood (2019) 134 (Supplement_1): 2292.

https://doi.org/10.1182/blood-2019-124440

Published: 2019

Journal Articles

360 o View of a Day Hospital Program Performing Exchange Transfusion and Outpatient Pain Management on Adults with Sickle Cell Disease

Natasha Wright, CRNP, Susan M. Sylvester, RN, Gregory J Kato, MD, Enrico Novelli, MD, Maria Nepa, PA-C, Jude C Jonassaint, RN, Laura De Castro, MD MHSc

Blood (2019) 134 (Supplement_1): 5873.

https://doi.org/10.1182/blood-2019-122397

Published: 2019

Journal Articles

Lactate Dehydrogenase to Carboxyhemoglobin Ratio As a Biomarker of Heme Release to Heme Processing Is Associated with Higher Tricuspid Regurgitant Jet Velocity and Early Death in Sickle Cell Disease

Annelies J. Van Vuren, MD, Laurel Mendelsohn, BS, Richard van Wijk, PhD, Caterina P. Minniti, MD, John Baird, MD, Gregory J Kato, MD, Eduard J. van Beers, MD PhD

Blood (2019) 134 (Supplement_1): 2274.

https://doi.org/10.1182/blood-2019-124048

Published: 2019

Journal Articles

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Tirthadipa Pradhan, Prithu Sundd, PhD, Satdarshan Pal Monga, Mark T Gladwin, MD, Gregory J Kato, MD

Blood (2019) 134 (Supplement_1): 958.

https://doi.org/10.1182/blood-2019-131921

Published: 2019

Journal Articles

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Samit Ghosh, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2018) 132 (Supplement 1): 2392.

https://doi.org/10.1182/blood-2018-99-113451

Published: 2018

Journal Articles

Assessment of Iron Overload Impact on QTc Interval in Patients with Sickle Cell Disease

Gilbert Bader, MD, Gregory J. Kato, MD, Suvankar Majumdar, MBCHB, James Pollard, MD, Jarrod Knudson, MD, Neil Shannon, Tanyanan Tanawuttiwat, MD, Clinton Carroll, MD, Joseph Maher, MD

Blood (2018) 132 (Supplement 1): 3673.

https://doi.org/10.1182/blood-2018-99-115125

Published: 2018

Journal Articles

Clinical and Laboratory Predictors of 30-Day Hospital Readmission Risk in Adult Patients with Sickle Cell Disease

Seyed Mehdi Nouraie, PhD MD, Melissa Saul, MS, Enrico M Novelli, MD MS, Gregory J. Kato, MD, Mark T Gladwin, MD

Blood (2018) 132 (Supplement 1): 2384.

https://doi.org/10.1182/blood-2018-99-115248

Published: 2018

Journal Articles

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3468.

https://doi.org/10.1182/blood.V130.Suppl_1.3468.3468

Published: 2017

Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Neutrophil Extracellular Traps Promote Lung Arteriole Occlusion in Sickle Cell Disease

Ravi Vats, MSc, Margaret F. Bennewitz, PhD, Maritza Ann Jimenez, BS, Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Jesus Tejero, PhD, Cheryl Hillery, MD, Gregory J. Kato, MD, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2017) 130 (Supplement 1): 2243.

https://doi.org/10.1182/blood.V130.Suppl_1.2243.2243

Published: 2017

Journal Articles

Hairy Platelet-Derived Extracellular Vesicles Promote Lung Vaso-Occlusion in Sickle Cell Disease

Prithu Sundd, PhD, Maritza Ann Jimenez, BS, Margaret F. Bennewitz, PhD, Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Gregory J. Kato, MD, Mark T Gladwin, MD

Blood (2017) 130 (Supplement 1): 958.

https://doi.org/10.1182/blood.V130.Suppl_1.958.958

Published: 2017

Journal Articles

Steady State Serum Albumin Level Independently Predicts Risk of Renal Dysfunction, Elevated TRV and Death in Adults with Sickle Cell Disease Screened in the Walk-Phasst Study

Nithya Sritharan, MD, Seyed Mehdi Nouraie, PhD MD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 4784.

https://doi.org/10.1182/blood.V130.Suppl_1.4784.4784

Published: 2017

Journal Articles

Biomarker Discovery: Novel Insights into Red Blood Cell Metabolomics in Patients with Sickle Cell Disease at Risk for Early Mortality

Claudia R. Morris, MD, Chunyu Ma, Shuzhao Li, Dean Jones, Lou Ann Brown, PhD, Roberto F. Machado, MD, Gregory J. Kato, MD, Yingze Zhang, PhD, Seyed Mehdi Nouraie, PhD MD, Mark T Gladwin, MD

Blood (2017) 130 (Supplement 1): 4772.

https://doi.org/10.1182/blood.V130.Suppl_1.4772.4772

Published: 2017

NARROW

Microvascular Stasis Inhibition By Hemopexin in the Townes Mouse Model of Sickle Cell Disease

Prevention of Heme-Induced Human Endothelial Cell Activation By Hemopexin in Vitro

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

Nrf2 Null Mice Are Deficient in CD169 + Macrophages, Associated with Impaired Erythroid Response and Delayed Recovery from Acute Blood Loss

A Prospective Phase II, Open-Label, Single-Arm, Multicenter Study to Assess the Efficacy and Safety of SEG101 (Crizanlizumab) in Sickle Cell Disease Patients with Priapism (SPARTAN)

Macrophage Hypercellularity Accompanies Erythroid Hyperplasia in Sickle Cell Mice and during Recovery from Blood Loss in Wild Type Mice

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

A Phase II Trial of Topical Sodium Nitrite in Patients with Sickle Cell Disease and Leg Ulcers

360 o View of a Day Hospital Program Performing Exchange Transfusion and Outpatient Pain Management on Adults with Sickle Cell Disease

Lactate Dehydrogenase to Carboxyhemoglobin Ratio As a Biomarker of Heme Release to Heme Processing Is Associated with Higher Tricuspid Regurgitant Jet Velocity and Early Death in Sickle Cell Disease

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Assessment of Iron Overload Impact on QTc Interval in Patients with Sickle Cell Disease

Clinical and Laboratory Predictors of 30-Day Hospital Readmission Risk in Adult Patients with Sickle Cell Disease

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Neutrophil Extracellular Traps Promote Lung Arteriole Occlusion in Sickle Cell Disease

Hairy Platelet-Derived Extracellular Vesicles Promote Lung Vaso-Occlusion in Sickle Cell Disease

Steady State Serum Albumin Level Independently Predicts Risk of Renal Dysfunction, Elevated TRV and Death in Adults with Sickle Cell Disease Screened in the Walk-Phasst Study

Biomarker Discovery: Novel Insights into Red Blood Cell Metabolomics in Patients with Sickle Cell Disease at Risk for Early Mortality

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American Society of Hematology

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ASH Publications

American Society of Hematology

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