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Journal Articles

Single and Dual Targeting Chimeric Antigen Receptor T-Cell Therapy in Acute Myeloid Leukemia

Sneha Chitre, PhD, Joop Gaken, PhD, Andrea Venuso, Masters, Ghulam J. Mufti, Professor

Blood (2020) 136 (Supplement 1): 25.

https://doi.org/10.1182/blood-2020-142013

Published: 2020

Journal Articles

Mir-181c Modulates T Cell Function By Regulating the Expression of BRK1

Shok Ping Lim, Donal McLornan, MB, Bch (Hons), PhD MRCP, FRCPath, Nikolaos Ioannou, David Darling, Alan G. Ramsay, PhD, Joop Gäken, PhD, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath

Blood (2016) 128 (22): 132.

https://doi.org/10.1182/blood.V128.22.132.132

Published: 2016

Journal Articles

Comparison of Peripheral Blood and Bone Marrow Molecular Profiling in Primary Myelodysplastic Syndromes (MDS)

Azim M Mohamedali, PhD, Joop Gaken, PhD, Momin Ahmed, MD PhD, Austin Kulasekararaj, Alexander E Smith, PhD, Farook Malik, PhD, Ghulam Mufti, MD DM, FRCP, FRCPath

Blood (2014) 124 (21): 4655.

https://doi.org/10.1182/blood.V124.21.4655.4655

Published: 2014

Journal Articles

RPL27A Is a Target for Mir-595 and Contributes to Myelodysplastic Phenotype through Ribosomal Dysgenesis

Heba A Alkhatabi, MSc, Joop Gaken, PhD, Austin Kulasekararaj, Shengjiang Tan, PhD, Farooq Malik, BSc, PhD, Alan John Warren, PhD FRCP, FRCPath, FMedSci, Thomas Seidl, David C Darling, PhD, Ghulam Mufti, MD DM, FRCP, FRCPath

Blood (2014) 124 (21): 1895.

https://doi.org/10.1182/blood.V124.21.1895.1895

Published: 2014

Journal Articles

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

Austin G. Kulasekararaj, Jie Jiang, Alexander E. Smith, Azim M. Mohamedali, Syed Mian, Shreyans Gandhi, Joop Gaken, Barbara Czepulkowski, Judith C. W. Marsh, Ghulam J. Mufti

Blood (2014) 124 (17): 2698–2704.

https://doi.org/10.1182/blood-2014-05-574889

Published: 2014

Includes: Supplemental data

Journal Articles

Comprehensive Mutational Screening Of 5-Azacitidne Treated Myelodysplastic Syndrome (MDS) Patients Fails To Identify a Specific Mutational Profile Predicting Response To Therapy

Austin G. Kulasekararaj, Azim M Mohamedali, PhD, Alexander E Smith, PhD, Syed A Mian, Nazia Matto, Terry J Gaymes, DPhil, Nicholas Lea, PhD, Joop Gaken, PhD, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2013) 122 (21): 2792.

https://doi.org/10.1182/blood.V122.21.2792.2792

Published: 2013

Journal Articles

Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome

Azim M. Mohamedali, Heba Alkhatabi, Austin Kulasekararaj, Sneha Shinde, Syed Mian, Farooq Malik, Alexander E. Smith, Joop Gäken, Ghulam J. Mufti

Blood (2013) 122 (4): 567–570.

https://doi.org/10.1182/blood-2012-12-471847

Published: 2013

Includes: Supplemental data

Journal Articles

Utility of Peripheral Blood for Cytogenetic and Mutation Analysis in Myelodysplastic Syndrome

Heba A Alkhatabi, MSc, Azim M Mohamedali, PhD, Austin G Kulasekararaj, Sneha Shinde, Msc., Joop Gaken, PhD, Syed A Mian, MSc, Alexander E Smith, PhD, Ghulam J. Mufti, MD

Blood (2012) 120 (21): 1707.

https://doi.org/10.1182/blood.V120.21.1707.1707

Published: 2012

Journal Articles

Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency,

Jie Jiang, PhD, Austin G Kulasekararaj, Pramila Krishnamurthy, Alexander E Smith, PhD, Syed A Mian, Shreyans Gandhi, Janet Hayden, Joop Gaken, Modupe Elebute, Robin M. Ireland, FRCP, FRCPath, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 3826.

https://doi.org/10.1182/blood.V118.21.3826.3826

Published: 2011

Journal Articles

TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis

Austin G Kulasekararaj, Alexander E Smith, PhD, Syed A Mian, Pramila Krishnamurthy, Azim M Mohamedali, PhD, Nicholas C Lea, PhD, Janet Hayden, Joop Gaken, Modupe Elebute, Robin M. Ireland, FRCP, FRCPath, Sabine Pomplun, ZiYi Lim, MD, Judith C. W. Marsh, Prof MD PhD, Ghulam J. Mufti, MD

Blood (2011) 118 (21): 792.

https://doi.org/10.1182/blood.V118.21.792.792

Published: 2011

Journal Articles

A Functional Assay for MicroRNA Target Identification and Validation

Joop Gaken, Azim Mohamedali, PHD, Jie Jiang, Farooq Malik, Austin G Kulasekararaj, Farzin Farzaneh, DPhil, Mahvash Tavassoli, Ghulam J. Mufti, DM, FRCP, FRCPath

Blood (2010) 116 (21): 3874.

https://doi.org/10.1182/blood.V116.21.3874.3874

Published: 2010

Journal Articles

Apoptin Induced Tumour Specific Killing Via Protein Kinase C Isoforms: A Potential Therapeutic Strategy In Plasma Cell Dyscrasias

Jie Jiang, Daryl Cole, Sr., Nigel Westwood, Lee Macpherson, Farzin Farzaneh, Ghulam J. Mufti, DM, FRCP, FRCPath, Mahvash Tavassoli, Joop Gaken

Blood (2010) 116 (21): 5039.

https://doi.org/10.1182/blood.V116.21.5039.5039

Published: 2010

Journal Articles

Polycomb Complex Group Gene Mutations and Their Prognostic Relevance In 5-Azacitidine Treated Myelodysplastic Syndrome Patients

Blood (2010) 116 (21): 125.

https://doi.org/10.1182/blood.V116.21.125.125

Published: 2010

Journal Articles

Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value

Alexander E. Smith, Azim M. Mohamedali, Austin Kulasekararaj, ZiYi Lim, Joop Gäken, Nicholas C. Lea, Bartlomiej Przychodzen, Syed A. Mian, Erick E. Nasser, Claire Shooter, Nigel B. Westwood, Corinna Strupp, Norbert Gattermann, Jaroslaw P. Maciejewski, Ulrich Germing, Ghulam J. Mufti

Blood (2010) 116 (19): 3923–3932.

https://doi.org/10.1182/blood-2010-03-274704

Published: 2010

Includes: Supplemental data

Journal Articles

Prevalence of 46/1 JAK2 Haplotype in Patients with Budd-Chiari Syndrome with and without JAK2V617F and TET2 Mutations.

Nicholas C Lea, PhD, Lara N Roberts, Raj K Patel, Rachel Westbrook, Michael A Heneghan, Azim M Mohamedali, PhD, Alex E Smith, Atiyeh Abdallah, Nigel Westwood, PhD, CSci, FIBMS, Trisevgeni Kontou, Deborah Yallop, BSc, FRCPath, MB, BS, MRCP, Roopen Arya, Antonio Pagliuca, MBBS, FRCP, FRCPath, MA, Joop Gaken, PhD, Nigel D Heaton, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath

Blood (2009) 114 (22): 434.

https://doi.org/10.1182/blood.V114.22.434.434

Published: 2009

Journal Articles

Deep Sequencing the Tet2 Gene in 360 Patients with Myeloid Neoplasms Provides a Comprehensive and Quantitative Mutation Map and Reveals Low Level Mutant Clones.

Alexander E Smith, Azim M Mohamedali, PhD, Syed a Mian, Technician, Nicholas C Lea, BSc, PhD, Nigel Westwood, PhD, CSci, FIBMS, Austin G Kulasekararaj, Joop Gaken, PhD, Corinna Strupp, Norbert Gattermann, MD, PhD, Ulrich Germing, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath

Blood (2009) 114 (22): 733.

https://doi.org/10.1182/blood.V114.22.733.733

Published: 2009

Journal Articles

High Resolution Genomic Mapping of Breast Cancer Derived T-MDS/TAML

Azim M Mohamedali, PhD, Natalie Twine, MSc, Joop Gaken, PhD, Nigel Westwood, PhD, CSci, FIBMS, Nicholas Lea, PhD, Rajani Chelliah, MSc, Detlef Haase, MD, PhD, Ghulam J Mufti, FRCP, FRCPath

Blood (2008) 112 (11): 2692.

https://doi.org/10.1182/blood.V112.11.2692.2692

Published: 2008

Journal Articles

MicroRNA Expression Profiling of High and Low Risk MDS

Joop Gaken, PhD, Azim M Mohamedali, PhD, Natalie Twine, Nigel Westwood, PhD, CSCI, FIBMS, Barbara Czepulkowski, Saousan Chehade, Lynn S Quek, Nicholas Lea, PhD, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath

Blood (2008) 112 (11): 3645.

https://doi.org/10.1182/blood.V112.11.3645.3645

Published: 2008

Journal Articles

High Resolution Molecular Analysis of 5q- Syndrome Patients at Diagnosis and Following Lenalidomide Therapy

Azim M Mohamedali, PhD, Nicholas Lea, PhD, Natalie Twine, MSc, Joop Gaken, PhD, Rajani Chelliah, MSc, Nigel Westwood, PhD, CSci, FIBMS, Ghulam J Mufti, FRCP, FRCPath

Blood (2008) 112 (11): 225.

https://doi.org/10.1182/blood.V112.11.225.225

Published: 2008

Journal Articles

Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes

Azim Mohamedali, Joop Gäken, Natalie A. Twine, Wendy Ingram, Nigel Westwood, Nicholas C. Lea, Janet Hayden, Nora Donaldson, Carlo Aul, Norbert Gattermann, Aristotle Giagounidis, Ulrich Germing, Alan F. List, Ghulam J. Mufti

Blood (2007) 110 (9): 3365–3373.

https://doi.org/10.1182/blood-2007-03-079673

Published: 2007

Includes: Supplemental data

NARROW

Single and Dual Targeting Chimeric Antigen Receptor T-Cell Therapy in Acute Myeloid Leukemia

Mir-181c Modulates T Cell Function By Regulating the Expression of BRK1

Comparison of Peripheral Blood and Bone Marrow Molecular Profiling in Primary Myelodysplastic Syndromes (MDS)

RPL27A Is a Target for Mir-595 and Contributes to Myelodysplastic Phenotype through Ribosomal Dysgenesis

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

Comprehensive Mutational Screening Of 5-Azacitidne Treated Myelodysplastic Syndrome (MDS) Patients Fails To Identify a Specific Mutational Profile Predicting Response To Therapy

Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome

Utility of Peripheral Blood for Cytogenetic and Mutation Analysis in Myelodysplastic Syndrome

Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency,

TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis

A Functional Assay for MicroRNA Target Identification and Validation

Apoptin Induced Tumour Specific Killing Via Protein Kinase C Isoforms: A Potential Therapeutic Strategy In Plasma Cell Dyscrasias

Polycomb Complex Group Gene Mutations and Their Prognostic Relevance In 5-Azacitidine Treated Myelodysplastic Syndrome Patients

Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value

Prevalence of 46/1 JAK2 Haplotype in Patients with Budd-Chiari Syndrome with and without JAK2V617F and TET2 Mutations.

Deep Sequencing the Tet2 Gene in 360 Patients with Myeloid Neoplasms Provides a Comprehensive and Quantitative Mutation Map and Reveals Low Level Mutant Clones.

High Resolution Genomic Mapping of Breast Cancer Derived T-MDS/TAML

MicroRNA Expression Profiling of High and Low Risk MDS

High Resolution Molecular Analysis of 5q- Syndrome Patients at Diagnosis and Following Lenalidomide Therapy

Prevalence and prognostic significance of allelic imbalance by single-nucleotide polymorphism analysis in low-risk myelodysplastic syndromes

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American Society of Hematology

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American Society of Hematology

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