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Nikolaos Ioannou
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Journal Articles

Ibrutinib-based therapy reinvigorates CD8 + T cells compared to chemoimmunotherapy: immune monitoring from the E1912 trial

Clinical Trials & Observations Brief Report
Despoina Papazoglou, Xin Victoria Wang, Tait D. Shanafelt, Connie E. Lesnick, Nikolaos Ioannou, Giulia De Rossi, Sylvia Herter, Marina Bacac, Christian Klein, Martin S. Tallman, Neil E. Kay, Alan G. Ramsay
Journal: Blood
Blood (2024) 143 (1): 57–63.
https://doi.org/10.1182/blood.2023020554
Published: 2024
Includes: Supplemental data
Journal Articles

Expansion of T Follicular Helper Cells in NLC Co-Cultures Reinforces the Concept of Co-Evolution of CLL and Supportive T Helper Cell Clones

Alicia Vaca, Nikolaos Ioannou, Mariela Sivina, Elisavet Vlachonikola, Karen Clise-Dwyer, Ekaterina Kim, Dan Li, Qing Ma, Alessandra Ferrajoli, Zeev E. Estrov, William G. Wierda, Piers E.M. Patten, Alan G. Ramsay, Jan A. Burger
Journal: Blood
Blood (2021) 138 (Supplement 1): 3716.
https://doi.org/10.1182/blood-2021-151351
Published: 2021
Journal Articles

The Tigit/CD226/CD155 Immunomodulatory Axis Is Deregulated in CLL and Contributes to B-Cell Anergy

Francesca Arruga, Andrea Iannello, Nikolaos Ioannou, Alberto Maria Todesco, Marta Coscia, Riccardo Moia, Gianluca Gaidano, John N. Allan, Richard Furman, Tiziana Vaisitti, Alan G. Ramsay, Silvia Deaglio
Journal: Blood
Blood (2021) 138 (Supplement 1): 3718.
https://doi.org/10.1182/blood-2021-150183
Published: 2021
Journal Articles

Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1/PD-1 immunotherapy

Nikolaos Ioannou, Patrick R. Hagner, Matt Stokes, Anita K. Gandhi, Benedetta Apollonio, Mariam Fanous, Despoina Papazoglou, Lesley-Ann Sutton, Richard Rosenquist, Rose-Marie Amini, Hsiling Chiu, Antonia Lopez-Girona, Preethi Janardhanan, Farrukh T. Awan, Jeffrey Jones, Neil E. Kay, Tait D. Shanafelt, Martin S. Tallman, Kostas Stamatopoulos, Piers E. M. Patten, Anna Vardi, Alan G. Ramsay
Journal: Blood
Blood (2021) 137 (2): 216–231.
https://doi.org/10.1182/blood.2020006073
Published: 2021
Includes: Supplemental data
Journal Articles

Allogeneic Anti-CD19 CAR T Cells Manufactured from Healthy Donors Provide a Unique Cellular Product with Distinct Phenotypic Characteristics Compared to CAR T Cells Generated from Patients with Mature B Cell Malignancies

Charlotte Graham, MRCP, BSc, MBBS, Agnieszka Jozwik, PhD, Ruby Quartey-Papafio, Nikolaos Ioannou, PhD MSc, BSc, Ana M Metelo, PhD, Carlo Scala, PhD, Glenda Dickson, PhD, Orla Stewart, Maria Almena-Carrasco, Elisa Peranzoni, Alan G. Ramsay, BSc,MSc,PhD, Sandra Dupouy, Pharm.D, PhD, Farzin Farzaneh, PhD, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Andrea Pepper, PhD, Reuben Benjamin, FRCPath, MRCP, MBBS, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3228.
https://doi.org/10.1182/blood-2019-123018
Published: 2019
Journal Articles

Longitudinal High-Throughput T Cell Repertoire Profiling of Chronic Lymphocytic Leukemia Patients Under Different Types of Treatment: Implications for Combination Strategies

Anna Vardi, MD PhD, Elisavet Vlachonikola, Nikolaos Ioannou, PhD MSc, BSc, Fotis Psomopoulos, Konstantia Kotta, Despoina Papazoglou, BSc, Maria Kotouza, Evangelia Koravou, Chrysi Galigalidou, Katerina Gemenetzi, Kostas Pasentsis, Michalis Iskas, Niki Stavroyianni, Achilles Anagnostopoulos, Alan G. Ramsay, BSc, MSc, PhD, Kostas Stamatopoulos, MD PhD, Anastasia Hadzidimitriou, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4400.
https://doi.org/10.1182/blood-2018-99-118006
Published: 2018
Journal Articles

Eliciting Anti-Tumor T Cell Immunity in Chronic Lymphocytic Leukemia (CLL) with PD-L1/PD-1 Blockade Is Enhanced By Avadomide Immunotherapy through the Triggering of Immunogenic Interferon Signaling

Nikolaos Ioannou, PhD MSc, BSc, Patrick R. Hagner, PhD, Fadi Towfic, PhD, Anita K. Gandhi, PhD, Kostas Stamatopoulos, MD PhD, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Anna Vardi, MD PhD, Alan G. Ramsay, BSc,MSc,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 237.
https://doi.org/10.1182/blood-2018-99-111605
Published: 2018
Journal Articles

Mir-181c Modulates T Cell Function By Regulating the Expression of BRK1

Shok Ping Lim, Donal McLornan, MB, Bch (Hons), PhD MRCP, FRCPath, Nikolaos Ioannou, David Darling, Alan G. Ramsay, PhD, Joop Gäken, PhD, Ghulam J Mufti, MBBS, DM, FRCP, FRCPath
Journal: Blood
Blood (2016) 128 (22): 132.
https://doi.org/10.1182/blood.V128.22.132.132
Published: 2016