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Journal Articles

Chronic Myeloid Leukemia (CML) Patients With Atypical e1a2 P190 BCR-ABL Translocation Show a Poor Response To Therapy With Tyrosine Kinase Inhibitors (TKI)

Carme Montoriol-Sabaté, Carolina Martínez-Laperche, PhD, P Jiménez-Gámiz, Rosa Collado, PhD, Alfredo Minguela-Puras, M.A. Piñán-Francés, B. Bellosillo, Joaquín Martínez-López, MD, PhD, Marcos González, MD, María José Larrayoz, PhD, MªJose Calasanz, PhD, Maria Teresa Gomez-Casares, MD, G. González-Brito, Gloria Soler, Jose Román, A. Jimenez-Velasco, Ismael Buno, PhD
Journal: Blood
Blood (2013) 122 (21): 5193.
https://doi.org/10.1182/blood.V122.21.5193.5193
Published: 2013
Journal Articles

Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma

Jose A. Richter-Larrea, Eloy F. Robles, Vicente Fresquet, Elena Beltran, Antonio J. Rullan, Xabier Agirre, Maria José Calasanz, Carlos Panizo, Jose A. Richter, Jesus M. Hernandez, Jose Roman-Gomez, Felipe Prosper, Jose A. Martinez-Climent
Journal: Blood
Blood (2010) 116 (14): 2531–2542.
https://doi.org/10.1182/blood-2010-02-268003
Published: 2010
Includes: Supplemental data
Journal Articles

Epigenomic Analysis of Acute Myeloid Leukemia Identifies Specific Patterns and Markes with Clinical and Biological Relevance.

Sara Alvarez, MD, PhD, Javier Suela, PhD, Ana Valencia, MD, Agustin Fernandez, PhD, Mark Wunderlich, MS, Xabier Agirre, PhD, Felipe Prosper, MD, Jose Ignacio Martin-Subero, PhD, Alba Maiques, MSc, Francesco Acquadro, MSc, Sandra Rodriguez-Perales, PhD, Maria J. Calasanz, PhD, Jose Roman-Gomez, MD, Reiner Siebert, MD, PhD, James C. Mulloy, PhD, José Cervera, MD, PhD, Miguel A. Sanz, MD, PhD, Manel Esteller, MD, PhD, Juan C Cigudosa, PhD
Journal: Blood
Blood (2009) 114 (22): 2394.
https://doi.org/10.1182/blood.V114.22.2394.2394
Published: 2009
Journal Articles

Epigenetic Silencing of BIM Mediates Chemotherapy Resistance of Patients with Burkitt Lymphoma That Can Be Overcome by Therapeutic Reactivation of BIM in Mouse and Human Lymphoma Models

Jose A. Richter, MSc, Antonio Rullan, Elena Beltran, MSc, Xabier Agirre, PhD, M.a José Calasanz, PhD, Jose Roman-Gomez, MD, Carlos Panizo, MD, Jesus M Hernandez, MD, PhD, Felipe Prosper, MD, Vicente Fresquet, PhD, Jose A. Martinez-Climent, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 607.
https://doi.org/10.1182/blood.V112.11.607.607
Published: 2008
Journal Articles

CTLA-4 polymorphisms and clinical outcome after allogeneic stem cell transplantation from HLA-identical sibling donors.

Arianne Pérez-García, Rafael De la Cámara, Jose Román-Gómez, Antonio Jiménez-Velasco, Maite Encuentra, Jose B. Nieto, Javier de la Rubia, Alvaro Urbano-Ispizúa, Salut Brunet, Arturo Iriondo, Marcos González, David Serrano, Ildefonso Espigado, Carlos Solano, Josep M. Ribera, Josep M. Pujal, Montserrat Hoyos, David Gallardo, the GVHD/Immunotherapy Committee of the Spanish Group of Hematopoietic Stem Cell Transplantation
Journal: Blood
Blood (2007) 110 (1): 461–467.
https://doi.org/10.1182/blood-2007-01-069781
Published: 2007
Includes: Supplemental data
Journal Articles

FLT3 Mutations in a Large Series of Patients with Acute Promyelocytic Leukemia Treated with All-Trans Retinoic Acid and Anthracycline Monochemotherapy.

Pau Montesinos, MD, Marcos Gonzalez, PhD, Maria Calasanz, PhD, Pascual Bolufer, PhD, Dolors Colomer, PhD, Jose Roman, PhD, Maria Teresa Gomez, PhD, Joaquin Martinez, PhD, Elena Amutio, PhD, Miguel Sanz, PhD
Journal: Blood
Blood (2006) 108 (11): 2348.
https://doi.org/10.1182/blood.V108.11.2348.2348
Published: 2006
Journal Articles

Improved Prediction of Acute Leukemia Relapse after Allogeneic SCT by Chimerism Analysis of Null Alleles and Indel Polymorphisms with Real-Time Quantitative PCR.

Antonio Jimenez-Velasco, MD, Manuel Barrios, MD, PhD, Jose Roman-Gomez, MD, PhD, German Navarro, PhD, Ismael Buño, PhD, Jose L. Diez-Martin, MD, PhD, Antonio Torres, MD, PhD, Ana I. Heiniger, MD
Journal: Blood
Blood (2004) 104 (11): 1650.
https://doi.org/10.1182/blood.V104.11.1650.1650
Published: 2004
Journal Articles

European Multicenter Experience on Idiopathic Hypereosinophilic Syndrome (HES) with FIP1L1-PDGFRA Rearrangement treated with Imatinib.

Giovanni Martinelli, Jane Apperley, Andreas Reiter, Nicholas P. Cross, Daniela Cilloni, David Grimwade, Andreas Hochhaus, Emanuela Ottaviani, Jan Cools, Lionel Prin, Michele Malagola, C Walz, Claude Preudhomme, Francesca Messa, Michela Rondoni, Enrico Gottardi, Gianantonio Rosti, Cristina Mecucci, Fabrizio Pane, Nicoletta Testoni, Simona Soverini, Serena Merante, Giuliana Alimena, Michele Baccarani, Rudiger Hehlmann, Anna Aventin, Anna Sureda, Jose-Roman Gomez, Justus Duyster, Gregor Verhoef, Giuseppe Saglio
Journal: Blood
Blood (2004) 104 (11): 1507.
https://doi.org/10.1182/blood.V104.11.1507.1507
Published: 2004
Journal Articles

Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymphoblastic leukemia

Clinical Trials & Observations
Jose Roman-Gomez, Antonio Jimenez-Velasco, Juan A. Castillejo, Xabier Agirre, Manuel Barrios, German Navarro, Francisco J. Molina, Maria J. Calasanz, Felipe Prosper, Anabel Heiniger, Antonio Torres
Journal: Blood
Blood (2004) 104 (8): 2492–2498.
https://doi.org/10.1182/blood-2004-03-0954
Published: 2004
Journal Articles

5′ CpG island hypermethylation is associated with transcriptional silencing of the p21 CIP1/WAF1/SDI1 gene and confers poor prognosis in acute lymphoblastic leukemia

Jose Roman-Gomez, Juan Antonio Castillejo, Antonio Jimenez, Maria Gracia Gonzalez, Fernanda Moreno, Maria del Carmen Rodriguez, Manuel Barrios, Juan Maldonado, Antonio Torres
Journal: Blood
Blood (2002) 99 (7): 2291–2296.
https://doi.org/10.1182/blood.V99.7.2291
Published: 2002
Journal Articles

Molecular analysis of lineage-specific chimerism and minimal residual disease by RT-PCR of p210 BCR-ABL and p190 BCR-ABL after allogeneic bone marrow transplantation for chronic myeloid leukemia: increasing mixed myeloid chimerism and p190 BCR-ABL detection precede cytogenetic relapse

Josefina Serrano, Jose Roman, Joaquin Sanchez, Antonio Jimenez, Juan A. Castillejo, Concepcion Herrera, Maria Gracia Gonzalez, Luisa Reina, Maria del Carmen Rodriguez, Miguel A. Alvarez, Juan Maldonado, Antonio Torres
Journal: Blood
Blood (2000) 95 (8): 2659–2665.
https://doi.org/10.1182/blood.V95.8.2659
Published: 2000