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Karl-Heinz Heider
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Journal Articles

BI 836826, a Novel Fc-Engineered Antibody in Combination with Phosphoinositide-3-Kinase Inhibitor for Treatment of High Risk Chronic Lymphocytic Leukemia and Lymphoma

Free
Deborah M Stephens, DO, Kyle A. Beckwith, PhD, Priscilla Do, BS, Carolyn Cheney, BS, Xiaokui Mo, PhD MAS, Karilyn Larkin, MD, Jeffrey Jones, MD MPH, Farrukh T. Awan, Laura Grosmaire, PhD, Randy Jones, PhD, Julie DiPaolo, PhD, Stacey Tannheimer, Karl-Heinz Heider, PhD, John C. Byrd, MD, Natarajan Muthusamy, DVM, PhD
Journal: Blood
Blood (2016) 128 (22): 2767.
https://doi.org/10.1182/blood.V128.22.2767.2767
Published: 2016
Journal Articles

Decitabine enhances anti-CD33 monoclonal antibody BI 836858–mediated natural killer ADCC against AML blasts

Free
Sumithira Vasu, Shun He, Carolyn Cheney, Bhavani Gopalakrishnan, Rajeswaran Mani, Gerard Lozanski, Xiaokui Mo, Veronica Groh, Susan P. Whitman, Renate Konopitzky, Christian Kössl, Donna Bucci, David M. Lucas, Jianhua Yu, Michael A. Caligiuri, William Blum, Paul J. Adam, Eric Borges, Bjoern Rueter, Karl-Heinz Heider, Guido Marcucci, Natarajan Muthusamy
Journal: Blood
Blood (2016) 127 (23): 2879–2889.
https://doi.org/10.1182/blood-2015-11-680546
Published: 2016
Includes: Supplemental data
Journal Articles

Novel Therapeutic Approach to Improve Hematopoiesis By Targeting Myeloid Derived Suppressor Cells with a Humanized Anti-CD33 Antibody

Free
Erika A Eksioglu, PhD, Karl-Heinz Heider, PhD, Bjoern Rueter, MD, Alexis Burnette, Max Wei, Kathy McGraw, Ashley A Basiorka, Parthik Patel, Jeffrey Lancet, Rami Komrokji, MD, Alan F. List, MD, Sheng Wei, MD
Journal: Blood
Blood (2014) 124 (21): 4597.
https://doi.org/10.1182/blood.V124.21.4597.4597
Published: 2014
Journal Articles

BI 836826, a Novel Fc-Engineered Antibody in Combination with Phosphoinositide-3-Kinase Inhibitor for Treatment of High Risk Chronic Lymphocytic Leukemia

Free
Deborah M Stephens, DO, Kyle A Beckwith, B.S., Carolyn Cheney, B.S, Xiaokui Mo, PhD MAS, Joseph M Flynn, D.O., MPH, Jeffrey A. Jones, MD, Kami J. Maddocks, MD, Karl-Heinz Heider, PhD, Natarajan Muthusamy, DVM, PhD, John C. Byrd, MD
Journal: Blood
Blood (2014) 124 (21): 4681.
https://doi.org/10.1182/blood.V124.21.4681.4681
Published: 2014
Journal Articles

Decitabine Or 5-Azacitidine Pre-Treatment Does Not Compromise The Novel Fc-Engineered Antibody Mab 33.1-Mediated ADCC Against Primary AML Blasts - A Rationale For Combination Therapy

Free
Shun He, PhD, Carolyn Cheney, Susan P. Whitman, PhD, Jianhua Yu, PhD, Sumithira Vasu, MBBS, William Blum, MD, Karl-Heinz Heider, PhD, Guido Marcucci, MD, Natarajan Muthusamy, DVM, Ph.D
Journal: Blood
Blood (2013) 122 (21): 3959.
https://doi.org/10.1182/blood.V122.21.3959.3959
Published: 2013
Journal Articles

A Novel Fc-Engineered Antibody to CD33 with Enhanced ADCC Activity for Treatment of AML

Free
Karl-Heinz Heider, PhD, Renate Konopitzky, PhD, Elinborg Ostermann, PhD, Herbert Lamche, PhD, Zaruhi Kuepcue, PhD, Christian Koessl, Ph.D., Paul Adam, Ph.D., Eric Borges, PhD
Journal: Blood
Blood (2012) 120 (21): 1363.
https://doi.org/10.1182/blood.V120.21.1363.1363
Published: 2012
Journal Articles

A novel Fc-engineered monoclonal antibody to CD37 with enhanced ADCC and high proapoptotic activity for treatment of B-cell malignancies

Free
Karl-Heinz Heider, Kerstin Kiefer, Thorsten Zenz, Matthias Volden, Stephan Stilgenbauer, Elinborg Ostermann, Anke Baum, Herbert Lamche, Zaruhi Küpcü, Alexander Jacobi, Steffen Müller, Ulrich Hirt, Günther R. Adolf, Eric Borges
Journal: Blood
Blood (2011) 118 (15): 4159–4168.
https://doi.org/10.1182/blood-2011-04-351932
Published: 2011
Includes: Supplemental data
Journal Articles

Exceptional In Vitro Activity of CD37 Antibodies In CLL

Free
Thorsten Zenz, MD, Matthias Volden, Theresa Mast, Karsten Nordhausen, Dirk Winkler, MD, Andrea Schnaiter, MD, Andreas Buehler, MD, Karl-Heinz Heider, PhD, Volker Reichardt, MD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD
Journal: Blood
Blood (2010) 116 (21): 2460.
https://doi.org/10.1182/blood.V116.21.2460.2460
Published: 2010
Journal Articles

Novel Fc-Engineered Antibodies to CD37 with Pro-Apoptotic and Enhanced ADCC Activity

Free
Karl-Heinz Heider, PhD, Elinborg Ostermann, PhD, Herbert Lamche, PhD, Zaruhi Kuepcue, PhD, Alexander Jacobi, PhD, Renate Konopitzky, PhD, Ulrich Hirt, PhD, Volker Reichardt, MD, Eric Borges, PhD
Journal: Blood
Blood (2010) 116 (21): 3916.
https://doi.org/10.1182/blood.V116.21.3916.3916
Published: 2010