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Journal Articles

Defining the Primate T Cell Transcriptome during Graft Versus Host Disease: New Data Implicating the Hedgehog and Aurora Kinase Pathways in Pathogenesis and Prevention

Scott N. Furlan, MD, Benjamin Watkins, MD, Ryan P Flynn, Swetha Ramakrishnan, Karnail Singh, PhD, Cynthia R. Giver, PhD, Kelly Hanby, Linda Stempora, Aneesah P. Garrett, Carly GK Ziegler, Gregory Tharp, Steven Bosinger, Bruce R. Blazar, MD, Edmund K. Waller, MD PhD, Leslie S. Kean, MD PhD

Blood (2014) 124 (21): 2432.

https://doi.org/10.1182/blood.V124.21.2432.2432

Published: 2014

Journal Articles

Rapamycin Rescues The Rapid Disappearance and Loss Of Phenotypic Integrity Of Autologous, Ex-Vivo Expanded Rhesus Macaque Natural Regulatory T Cells After Adoptive Transfer

Karnail Singh, Ph.D., Linda Stempora, Allan D Kirk, MD, PhD, Christian P Larsen, MD, DPhil, Bruce R Blazar, MD, Leslie S. Kean

Blood (2013) 122 (21): 895.

https://doi.org/10.1182/blood.V122.21.895.895

Published: 2013

Journal Articles

Significant mobilization of both conventional and regulatory T cells with AMD3100

Leslie S. Kean, Sharon Sen, Olusegun Onabajo, Karnail Singh, Jennifer Robertson, Linda Stempora, Aylin C. Bonifacino, Mark E. Metzger, Daniel E. L. Promislow, Joseph J. Mattapallil, Robert E. Donahue

Blood (2011) 118 (25): 6580–6590.

https://doi.org/10.1182/blood-2011-06-359331

Published: 2011

Includes: Supplemental data

Journal Articles

Sirolimus Inhibits Proliferation but Enhances Suppressive Activity of Rhesus Macaque Natural CD4 Regulatory T Cells

Karnail Singh, Ph.D., Natalia Kozyr, Ph.D., Linda Stempora, Allan D Kirk, MD, PhD, Christian P Larsen, MD, DPhil, Bruce R. Blazar, MD, Leslie S. Kean, MD, PhD

Blood (2011) 118 (21): 1008.

https://doi.org/10.1182/blood.V118.21.1008.1008

Published: 2011

Journal Articles

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28 − CD8 + T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Blood (2010) 116 (24): 5403–5418.

https://doi.org/10.1182/blood-2010-06-289272

Published: 2010

Includes: Supplemental data

Journal Articles

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

Leslie Kean, MD, PhD, Sharon Sen, Mark E Metzger, Aylin Bonifacino, Karnail Singh, Robert E Donahue, VMD

Blood (2010) 116 (21): 350.

https://doi.org/10.1182/blood.V116.21.350.350

Published: 2010

Journal Articles

Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation

Karnail Singh, Swetha Srinivasan, Angela Panoskaltsis-Mortari, PhD, Sharon Sen, Kelly Hamby, Taylor Deane, Linda Stempora, Frank Leopardi, John Shires, Jonathan Beus, Benjamin Byrd, Bruce R. Blazar, MD, Leslie Kean, MD, PhD

Blood (2010) 116 (21): 2549.

https://doi.org/10.1182/blood.V116.21.2549.2549

Published: 2010

Journal Articles

GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression

Swetha Srinivasan, Weston P. Miller IV, MD, Angela Panoskalltsis-Mortari, Sharon Sen, Kelly Hamby, Taylor Deane, Linda Stempora, Karnail Singh, Jonathan Beus, Bruce R. Blazar, MD, Leslie Kean, MD, PhD

Blood (2010) 116 (21): 2550.

https://doi.org/10.1182/blood.V116.21.2550.2550

Published: 2010

Journal Articles

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin–like receptors

Gabriella Henel, Karnail Singh, Dapeng Cui, Sergey Pryshchep, Won-Woo Lee, Cornelia M. Weyand, Jörg J. Goronzy

Blood (2006) 107 (11): 4449–4457.

https://doi.org/10.1182/blood-2005-06-2519

Published: 2006

Includes: Supplemental data

NARROW

Defining the Primate T Cell Transcriptome during Graft Versus Host Disease: New Data Implicating the Hedgehog and Aurora Kinase Pathways in Pathogenesis and Prevention

Rapamycin Rescues The Rapid Disappearance and Loss Of Phenotypic Integrity Of Autologous, Ex-Vivo Expanded Rhesus Macaque Natural Regulatory T Cells After Adoptive Transfer

Significant mobilization of both conventional and regulatory T cells with AMD3100

Sirolimus Inhibits Proliferation but Enhances Suppressive Activity of Rhesus Macaque Natural CD4 Regulatory T Cells

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28 − CD8 + T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

Probing the Impact of AMD3100/GCSF Mobilization on the Peripheral Blood T Cell Content Using a Rhesus Macaque Model: Increased Proportions of FoxP3+/CD4+ T Cells Occur After Mobilization and Leukapheresis

Sirolimus and GvHD Control: the Rhesus Macaque GvHD Model Reveals That Sirolimus Preferentially Inhibits T Cell Proliferation While Permitting Breakthrough T cell Activation After MHC-Mismatched Hematopoietic Stem Cell Transplantation

GvHD After Haploidentical Transplant: A Novel, MHC-Defined Rhesus Macaque Model Identifies CD28-Negative CD8+ T Cells as a Reservoir of Breakthrough T Cell Proliferation During Costimulation Blockade and Sirolimus-Based Immunosuppression

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin–like receptors

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American Society of Hematology

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American Society of Hematology

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