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Journal Articles

A Phase Ib, Open-Label Study of Add on Therapy with CK0804 in Participants with Myelofibrosis and Suboptimal Response to Ruxolitinib

Lucia Masarova, Meixian Huang, Sharon Bledsoe, Naveen Pemmaraju, Tapan M. Kadia, Prithviraj Bose, Jo Ishizawa, Guillermo Montalban-Bravo, Mi-Ae Lyu, Ke Zeng, Tara Sadeghi, Ekatherine Asatiani, Simrit Parmar, Christopher R. Flowers, Hagop M. Kantarjian

Blood (2023) 142 (Supplement 1): 1813.

https://doi.org/10.1182/blood-2023-188051

Published: 2023

Journal Articles

CXCR4 Enriched T Regulatory Cells Preferentially Home to Bone Marrow and Decrease Inflammation

Meixian Huang, Mi-Ae Lyu, Ke Zeng, Tara Sadeghi, Lucia Masarova, Christopher R. Flowers, Simrit Parmar

Blood (2023) 142 (Supplement 1): 351.

https://doi.org/10.1182/blood-2023-188820

Published: 2023

Journal Articles

Adoptive Therapy with Allogeneic Cord Blood T Regulatory Cells Improves Transfusion Requirement in Bone Marrow Failure Syndromes

Tapan M. Kadia, Naveen Pemmaraju, Musa Yilmaz, Naval Daver, Li Li, Mi-Ae Lyu, Meixian Huang, Ke Zeng, Robin Cook, Simrit Parmar, Siddhartha Mukherjee, Tara Sadeghi, Courtney D. DiNardo, Ghayas C. Issa, Elias J. Jabbour, Gautam Borthakur, Nitin Jain, Srdan Verstovsek

Blood (2021) 138 (Supplement 1): 3875.

https://doi.org/10.1182/blood-2021-153864

Published: 2021

Journal Articles

Randomized, Multi-Center, Double-Blinded, Placebo Controlled Safety and Early Efficacy Trial of Cryopreserved Cord Blood Derived T-Regulatory Cell Infusions (CK0802) in the Treatment of COVID-19 Induced ARDS. (RESOLVE Trial)

Douglas E Gladstone, Christopher Howard, Mi-Ae Lyu, Jason Mock, Darryl Adams, Kevin Gibbs, Li Li, Meixian Huang, Ke Zeng, Franco D'Alessio, James Herlihy, Sergio Trevino, Parameswaran Hari, Tara Sadeghi, Simrit Parmar, Arthur Slutsky, Siddhartha Mukherjee

Blood (2021) 138 (Supplement 1): 828.

https://doi.org/10.1182/blood-2021-153616

Published: 2021

Journal Articles

Adoptive Therapy with Allogeneic Cord Blood T Regulatory Cells Show Safety and Early Clinical Signal in Primary Myelofibrosis

Tapan M. Kadia, MD, Naveen Pemmaraju, MD, Musa Yilmaz, MD, Li Li, MD, Mi-Ae Lyu, PhD, Meixian Huang, MD,PhD, Ke Zeng, MD, Simrit Parmar, MD, MSCI, Courtney D. DiNardo, MD MSCE, Naval Daver, MD, Ghayas C. Issa, MD, Elias Jabbour, MD, Gautam Borthakur, MD, Srdan Verstovsek, MD PhD

Blood (2020) 136 (Supplement 1): 41–42.

https://doi.org/10.1182/blood-2020-138585

Published: 2020

Journal Articles

Cord Blood T Regulatory Cells Can Dampen Cytokine Release Syndrome and Improve on Target Efficacy of CD19 CAR T Cells

Ke Zeng, MD, Li Li, MD, Meixian Huang, MD,PhD, Mi-Ae Lyu, PhD, Mitsutaka Nishimoto, MD, PhD, Hongbing Ma, MD, PhD, Tara Sadeghi, Loretta J. Nastoupil, MD, Krina K. Patel, MD, Sairah Ahmed, MD, Simrit Parmar, MD, MSCI

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-138812

Published: 2020

Journal Articles

Adoptive Therapy with Cord Blood T Regulatory Cells Enhances Anti-Myeloma Efficacy of T Cell Based Immunotherapies

Mitsutaka Nishimoto, MD PhD, Li Li, MD, Meixian Huang, MD,PhD, Mi-Ae Lyu, PhD, Ke Zeng, MD, Hongbing Ma, MD PhD, Tara Sadeghi, Sairah Ahmed, MD, Nina Shah, MD, Krina K. Patel, MD, Simrit Parmar, MD, MSCI

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-143142

Published: 2020

Journal Articles

Combination of Cord Blood T Regulatory Cells with Ruxolitinib Decreases Side Effects and Improves Survival in Xenogenic Graft Vs. Host Disease

Ke Zeng, MD, Meixian Huang, MD,PhD, Li Li, MD, Mi-Ae Lyu, PhD, Hongbing Ma, MD, Mitsutaka Nishimoto, MD,PhD, Tara Sadeghi, Sairah Ahmed, MD, Borje S. Andersson, MD, PhD, Simrit Parmar, MD, MSCI

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-140417

Published: 2020

Journal Articles

Adoptive Cord Blood T Regulatory Cell Therapy Leads to Resolution of Inflammation and Decreased Proteinuria in Lupus Nephritis

Mi-Ae Lyu, PhD, Joseph D. Khoury, MD, Meixian Huang, MD,PhD, Mitsutaka Nishimoto, MD PhD, Ke Zeng, MD, Li Li, MD, Hongbing Ma, MD PhD, Tara Sadeghi, Simrit Parmar, MD, MSCI

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-140420

Published: 2020

Journal Articles

Adoptive Therapy with Cord Blood Regulatory T Cells Can Treat Graft Vs Host Disease

Hongbing Ma, MD PhD, Ke Zeng, MD PhD, Mitsutaka Nishimoto, MD PhD, Mi-Ae Lyu, PhD, Meixian Huang, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 1940.

https://doi.org/10.1182/blood-2019-129395

Published: 2019

Journal Articles

Single Injection of Cord Blood Regulatory T Cells Can Delay the Manifestations of Systemic Lupus Erythematosus

Mi-Ae Lyu, PhD, Joseph D. Khoury, MD, Mitsutaka Nishimoto, MD PhD, Ke Zeng, MD PhD, Meixian Huang, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 1938.

https://doi.org/10.1182/blood-2019-131436

Published: 2019

Journal Articles

Cord Blood Regulatory T Cells Prevent Mutiple Myeloma Progression By Suppressing Inflammation

Mitsutaka Nishimoto, MD PhD, Ke Zeng, MD PhD, Meixian Huang, Mi-Ae Lyu, PhD, Nina D. Shah, MD, Swaminathan P. Iyer, MD, Robert Z. Orlowski, MD, PhD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 3095.

https://doi.org/10.1182/blood-2019-128418

Published: 2019

Journal Articles

Allogeneic Cord Blood Regulatory T Cells Can Prevent Graft Vs. Host Disease and Preserve Graft Vs Leukemia Effect: Update on Phase I/II Clinical Trial

Ke Zeng, MD PhD, Hongbing Ma, MD PhD, Uday Popat, MD, Yago Nieto, MD PhD, Stefan O. Ciurea, MD, Amanda L. Olson, MD, Mi-Ae Lyu, PhD, Meixian Huang, Mitsutaka Nishimoto, MD PhD, Muzaffar H. Qazilbash, MD, Jennifer D Ramos, RN, Elizabeth J. Shpall, MD, Richard E. Champlin, MD, Simrit Parmar, MBBS, Borje S Andersson, MD PhD

Blood (2019) 134 (Supplement_1): 4547.

https://doi.org/10.1182/blood-2019-127726

Published: 2019

Journal Articles

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Meixian Huang, Amit Verma, MBBS, Ke Zeng, MD PhD, Mi-Ae Lyu, PhD, Mitsutaka Nishimoto, MD PhD, Hongbing Ma, MD PhD, Zheng Yin, PhD, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 4446.

https://doi.org/10.1182/blood-2019-131948

Published: 2019

Journal Articles

Phase I Clinical Trial of CK0801 (cord blood regulatory T cells) in Patients with Bone Marrow Failure Syndrome (BMF) Including Aplastic Anemia, Myelodysplasia and Myelofibrosis

Tapan M. Kadia, MD, Hongbing Ma, MD PhD, Ke Zeng, MD PhD, Mitsutaka Nishimoto, MD PhD, Mi-Ae Lyu, PhD, Meixian Huang, Musa Yilmaz, MD, Courtney D. DiNardo, MDMSc, Ghayas C. Issa, MD, Simrit Parmar, MBBS, Swami P. Iyer, MD, Parameswaran Hari, MBBS, MD, Naval G. Daver, MD, Elias Jabbour, MD, Gautam M. Borthakur, MD, Srdan Verstovsek, MD PhD

Blood (2019) 134 (Supplement_1): 1221.

https://doi.org/10.1182/blood-2019-127702

Published: 2019

Journal Articles

Adoptive Therapy with Cord Blood Regulatory T Cells Does Not Impair Anti-Leukemia Activity of Infused Donor Cells

Hongbing Ma, MD, Mitsutaka Nishimoto, MD PhD, Ke Zeng, PhD, Tuongvan D Nguyen, William Schuler, Joshua Kellner, Jaimol Peedikayil, PhD, Mi-Ae Lyu, Santhana Thangavelu-Devaraj, Simrit Parmar, MBBS

Blood (2018) 132 (Supplement 1): 5214.

https://doi.org/10.1182/blood-2018-99-119239

Published: 2018

Journal Articles

Construction of the Lentiviral and Electric Transfection Vectors Encoding Anti-Human CD30 or CD33 Chimeric Antigen Receptor (CAR) Gene and Respective Expression Injurkat Leukemia Cell Line

Ke Zeng, MD, Ting Niu, MD PhD

Blood (2014) 124 (21): 5950.

https://doi.org/10.1182/blood.V124.21.5950.5950

Published: 2014

NARROW

A Phase Ib, Open-Label Study of Add on Therapy with CK0804 in Participants with Myelofibrosis and Suboptimal Response to Ruxolitinib

CXCR4 Enriched T Regulatory Cells Preferentially Home to Bone Marrow and Decrease Inflammation

Adoptive Therapy with Allogeneic Cord Blood T Regulatory Cells Improves Transfusion Requirement in Bone Marrow Failure Syndromes

Randomized, Multi-Center, Double-Blinded, Placebo Controlled Safety and Early Efficacy Trial of Cryopreserved Cord Blood Derived T-Regulatory Cell Infusions (CK0802) in the Treatment of COVID-19 Induced ARDS. (RESOLVE Trial)

Adoptive Therapy with Allogeneic Cord Blood T Regulatory Cells Show Safety and Early Clinical Signal in Primary Myelofibrosis

Cord Blood T Regulatory Cells Can Dampen Cytokine Release Syndrome and Improve on Target Efficacy of CD19 CAR T Cells

Adoptive Therapy with Cord Blood T Regulatory Cells Enhances Anti-Myeloma Efficacy of T Cell Based Immunotherapies

Combination of Cord Blood T Regulatory Cells with Ruxolitinib Decreases Side Effects and Improves Survival in Xenogenic Graft Vs. Host Disease

Adoptive Cord Blood T Regulatory Cell Therapy Leads to Resolution of Inflammation and Decreased Proteinuria in Lupus Nephritis

Adoptive Therapy with Cord Blood Regulatory T Cells Can Treat Graft Vs Host Disease

Single Injection of Cord Blood Regulatory T Cells Can Delay the Manifestations of Systemic Lupus Erythematosus

Cord Blood Regulatory T Cells Prevent Mutiple Myeloma Progression By Suppressing Inflammation

Allogeneic Cord Blood Regulatory T Cells Can Prevent Graft Vs. Host Disease and Preserve Graft Vs Leukemia Effect: Update on Phase I/II Clinical Trial

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Phase I Clinical Trial of CK0801 (cord blood regulatory T cells) in Patients with Bone Marrow Failure Syndrome (BMF) Including Aplastic Anemia, Myelodysplasia and Myelofibrosis

Adoptive Therapy with Cord Blood Regulatory T Cells Does Not Impair Anti-Leukemia Activity of Infused Donor Cells

Construction of the Lentiviral and Electric Transfection Vectors Encoding Anti-Human CD30 or CD33 Chimeric Antigen Receptor (CAR) Gene and Respective Expression Injurkat Leukemia Cell Line

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American Society of Hematology

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American Society of Hematology

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