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Journal Articles

A STAT3 Degrader Demonstrates Pre-Clinical Efficacy in Venetoclax Resistant Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 2787.

https://doi.org/10.1182/blood-2023-186947

Published: 2023

Journal Articles

Microbial Metabolites Target Histone Deacetylases to Trigger Vascular Inflammation in Sickle Cell Disease

Lidiane S. Torres, Simone Sidoli, Huihui Li, Sofia De Oliveira, Paul S. Frenette, Andres Hidalgo, Keisuke Ito

Blood (2022) 140 (Supplement 1): 435–436.

https://doi.org/10.1182/blood-2022-169203

Published: 2022

Journal Articles

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

Claudia Morganti, PhD, Massimo Bonora, PhD, Kyoko Ito, Keisuke Ito, MD PhD

Blood (2019) 134 (Supplement_1): 1188.

https://doi.org/10.1182/blood-2019-125891

Published: 2019

Journal Articles

A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division.

Keisuke Ito, M.D., Ph.D., Arkaitz Carracedo, Ph.D., Fumio Arai, DDS, PhD, Ugo Ala, Ph.D., David Avigan, MD, Zachary Schafer, Ph.D., Ron M. Evans, PhD, Toshio Suda, MD, Chih-Hao Lee, Pier Paolo Pandolfi, MD, PhD

Blood (2012) 120 (21): 2327.

https://doi.org/10.1182/blood.V120.21.2327.2327

Published: 2012

Journal Articles

Targeting Leukemia Initiating Cells by MUC1-C Subunit Inhibition

Blood (2012) 120 (21): 3583.

https://doi.org/10.1182/blood.V120.21.3583.3583

Published: 2012

Journal Articles

Targeting Acute Myeloid Leukemia Stem Cells by MUC1-C Subunit Inhibition

Dina Stroopinsky, PhD, Jacalyn Rosenblatt, MD, MSc, Keisuke Ito, MD, PhD, Li Yin, Hasan Rajabi, PhD, Baldev Vasir, PhD, Turner Kufe, Brett Glotzbecker, MD, Katarina Luptakova, MD, Heidi Mills, BA, Robin Joyce, MD, Dimitrios Tzachanis, MD, PhD, Vassiliki A Boussiotis, MD, PhD, James Levine, MD, Ilene Galinsky, ANP, Richard Stone, MD, Pier Paolo Pandolfi, MD, PhD, Donald Kufe, MD, David Avigan, MD

Blood (2010) 116 (21): 848.

https://doi.org/10.1182/blood.V116.21.848.848

Published: 2010

Journal Articles

The Role of Nucleophosmin In Hematopoietic Stem Cells and the Pathogenesis of Myelodysplastic Syndrome

Keisuke Ito, MD, PhD, Paolo Sportoletti, MD, John G Clohessy, PhD, Grisendi Silvia, PhD, Pier Paolo Pandolfi, MD, PhD

Blood (2010) 116 (21): 95.

https://doi.org/10.1182/blood.V116.21.95.95

Published: 2010

Journal Articles

The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model

Ke Cheng, Paolo Sportoletti, Keisuke Ito, John G. Clohessy, Julie Teruya-Feldstein, Jeffery L. Kutok, Pier Paolo Pandolfi

Blood (2010) 115 (16): 3341–3345.

https://doi.org/10.1182/blood-2009-03-208587

Published: 2010

Includes: Supplemental data

Journal Articles

Foxo3a Is Essential for the Quiescence and Self-Renewal of Hematopoietic Stem Cells.

Kana Miyamoto, MD, Atsushi Hirao, M.D., Ph.D., Kiyomi Y. Araki, Ph.D., Fumio Arai, Ph.D., Kazuhito Naka, Ph.D., Keiyo Takubo, M.D., Sahoko Matsuoka, M.D., Ph.D., Satoshi Yamazaki, Keisuke Ito, M.D., Ph.D., Masako Ohmura, Ph.D., Kentaro Hosokawa, Mine Harada, M.D., Ph.D., Noboru Motoyama, Ph.D., Toshio Suda, M.D., Ph.D.

Blood (2006) 108 (11): 442.

https://doi.org/10.1182/blood.V108.11.442.442

Published: 2006

Journal Articles

Reactive Oxygen Species Control Hematopoietic Stem Cell-Niche Interaction through the Regulation of N-Cadherin.

Kentaro Hosokawa, Fumio Arai, DDS, PhD, Hiroki Yoshihara, MD, Keiyo Takubo, MD, Keisuke Ito, MD, PhD, Sahoko Matsuoka, MD, PhD, Toshio Suda, MD

Blood (2006) 108 (11): 86.

https://doi.org/10.1182/blood.V108.11.86.86

Published: 2006

Journal Articles

Ubiquitin Ligase Component Fbw7 Regulates the Quiescence of Hematopoietic Stem Cells.

Sahoko Matsuoka, MD, PhD, Yuichi Oike, MD, PhD, Ichiro Onoyama, MD, PhD, Keiyo Takubo, MD, PhD, Keisuke Ito, MD, PhD, Fumio Arai, DDS, PhD, Yasuo Ikeda, MD, PhD, Keiko Nakayama, MD, PhD, Keiichi Nakayama, MD, PhD, Toshio Suda, MD, PhD

Blood (2006) 108 (11): 79.

https://doi.org/10.1182/blood.V108.11.79.79

Published: 2006

Journal Articles

Anti-Oxidant NAC Prevents Hypersensitivity, Immunodeficiency and Lymphomagenesis in Atm −/− Mice.

Keisuke Ito, MD, PhD, Fumio Arai, D.D., Ph.D, Sahoko Matsuoka, M.D., Ph.D., Yasuo Ikeda, M.D., Ph.D., Toshio Suda, M.D., Ph.D., Atsushi Hirao, M.D., Ph.D.

Blood (2006) 108 (11): 4753.

https://doi.org/10.1182/blood.V108.11.4753.4753

Published: 2006

Journal Articles

Inactivation of p38 MAPK Extends Self-Renewal Capacity of Haematopoietic Stem Cells.

Keisuke Ito, MD, PhD, Atsushi Hirao, MD, PhD, Fumio Arai, DD, PhD, Sahoko Matsuoka, MD, PhD, Keiyo Takubo, MD, Yasuo Ikeda, MD, PhD, Toshio Suda, MD, PhD

Blood (2005) 106 (11): 265.

https://doi.org/10.1182/blood.V106.11.265.265

Published: 2005

Journal Articles

Rb Regulates Erythroid Differentiation through Bcl-XL-Dependent Anti-Apoptotic Effect.

Sahoko Matsuoka, M.D., Ph.D., Atsushi Hirao, M.D., Ph.D., Fumio Arai, D.D.S., Ph.D., Keisuke Ito, M.D., Ph.D., Keiyo Takubo, M.D., Ph.D., Kana Nomiyama, M.D., Ph.D., Isao Hamaguchi, M.D., Ph.D., Yasuo Ikeda, M.D., Ph.D., Toshio Suda, M.D., Ph.D.

Blood (2004) 104 (11): 1261.

https://doi.org/10.1182/blood.V104.11.1261.1261

Published: 2004

Journal Articles

A Green Tea Component, Catechin, Induces Apoptosis of Human Myeloma Cells and Markedly Enhances Arsenic Trioxide-Induced Cytotoxicity Via Production of Reactive Oxygen Species (ROS).

Tomonori Nakazato, MD, Keisuke Ito, MD, Yoshitaka Miyakawa, MD, Yasuo Ikeda, MD, Masahiro Kizaki, MD

Blood (2004) 104 (11): 2475.

https://doi.org/10.1182/blood.V104.11.2475.2475

Published: 2004

Journal Articles

Regulation of Oxidative Stress by ATM Is Required for the Self-Renewal of Haematopoietic Stem Cells.

Keisuke Ito, M.D., Ph.D., Atsushi Hirao, M.D., Ph.D., Fumio Arai, D.D.S., Ph.D., Sahoko Matsuoka, M.D., Ph.D., Tak W. Mak, M.D., Ph.D., Toshio Suda, M.D., Ph.D.

Blood (2004) 104 (11): 369.

https://doi.org/10.1182/blood.V104.11.369.369

Published: 2004

Journal Articles

1′-Acetoxychavicol Acetate (ACA) Is a Novel NF-κB Inhibitor with Significant Activity Against Multiple Myeloma in Vitro and in Vivo .

Keisuke Ito, MD, Tomonori Nakazato, MD, Yoshitaka Miyakawa, MD, Ming Ji Xian, MD, Taketo Yamada, MD, Hajime Ohigashi, PhD, Yasuo Ikeda, MD, Masahiro Kizaki, MD

Blood (2004) 104 (11): 765.

https://doi.org/10.1182/blood.V104.11.765.765

Published: 2004

NARROW

A STAT3 Degrader Demonstrates Pre-Clinical Efficacy in Venetoclax Resistant Acute Myeloid Leukemia

Microbial Metabolites Target Histone Deacetylases to Trigger Vascular Inflammation in Sickle Cell Disease

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division.

Targeting Leukemia Initiating Cells by MUC1-C Subunit Inhibition

Targeting Acute Myeloid Leukemia Stem Cells by MUC1-C Subunit Inhibition

The Role of Nucleophosmin In Hematopoietic Stem Cells and the Pathogenesis of Myelodysplastic Syndrome

The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model

Foxo3a Is Essential for the Quiescence and Self-Renewal of Hematopoietic Stem Cells.

Reactive Oxygen Species Control Hematopoietic Stem Cell-Niche Interaction through the Regulation of N-Cadherin.

Ubiquitin Ligase Component Fbw7 Regulates the Quiescence of Hematopoietic Stem Cells.

Anti-Oxidant NAC Prevents Hypersensitivity, Immunodeficiency and Lymphomagenesis in Atm −/− Mice.

Inactivation of p38 MAPK Extends Self-Renewal Capacity of Haematopoietic Stem Cells.

Rb Regulates Erythroid Differentiation through Bcl-XL-Dependent Anti-Apoptotic Effect.

A Green Tea Component, Catechin, Induces Apoptosis of Human Myeloma Cells and Markedly Enhances Arsenic Trioxide-Induced Cytotoxicity Via Production of Reactive Oxygen Species (ROS).

Regulation of Oxidative Stress by ATM Is Required for the Self-Renewal of Haematopoietic Stem Cells.

1′-Acetoxychavicol Acetate (ACA) Is a Novel NF-κB Inhibitor with Significant Activity Against Multiple Myeloma in Vitro and in Vivo .

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American Society of Hematology

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American Society of Hematology

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