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Leigh Wood
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Journal Articles

Development of a Phase 1 Study Evaluating the Activity of Modular CAR T for Multiple Myeloma (MCARTY) Targeting BCMA and CD19 for Improved Persistence

Free
Lydia Sarah Hui Lee, Wen Chean Lim, Catriona Mactier, Juliana Dias Alves Pinto, Vitoria Pereira, Mhairi Vaughan, Louisa Green, Evie Lewin, John Garcia, Giulia Agliardi, Yashma Pathak, Riaz Jannoo, Leigh Wood, Bilyana Popova, Helen Holmes, Simon Thomas, Victoria Spanswick, William Wilson, Christopher Parrish, Rakesh Popat, Claire Roddie, Kwee Yong, Martin A. Pule
Journal: Blood
Blood (2023) 142 (Supplement 1): 350.
https://doi.org/10.1182/blood-2023-185085
Published: 2023
Journal Articles

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma

Free
Clinical Trials & Observations
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G. R. Peddareddigari, Nushmia Khokhar, Robert Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve A. O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin A. Pule
Journal: Blood
Blood (2023) 141 (20): 2470–2482.
https://doi.org/10.1182/blood.2022018598
Published: 2023
Includes: Supplemental data
Journal Articles

First in Human Study of AUTO4, a TRBC1-Targeting CAR T-Cell Therapy in Relapsed/Refractory TRBC1-Positive Peripheral T-Cell Lymphoma

Free
Kate Cwynarski, Gloria Iacoboni, Eleni Tholouli, Tobias F. Menne, David A. Irvine, Nivetha Balasubramaniam, Leigh Wood, Justin Shang, Yiyun Zhang, Silvia Basilico, Birgit Huber, Mary Vinson, Koki Lilova, Wolfram Brugger, Martin Pule
Journal: Blood
Blood (2022) 140 (Supplement 1): 10316–10317.
https://doi.org/10.1182/blood-2022-165971
Published: 2022
Journal Articles

Safety, Efficiency and Long-Term Follow-up of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Free
Claire Roddie, Juliana Dias Alves Pinto, Maeve A O'Reilly, Marina Mitsikakou, Eftychia Charalambous, Louisa Green, Mhairi Vaughan, Giulia Agliardi, John Garcia, Evie Lewin, Mark W. Lowdell, Maria A V Marzolini, Leigh Wood, Helen Holmes, Yenting Ngai, Bilyana Popova, William Wilson, Sangeetha Kunaseelan, Victoria Spanswick, Helen Lowe, Leah Ensell, John A. Hartley, Simon Morley, David C. Linch, Adrian Bloor, David A. Irvine, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2022) 140 (Supplement 1): 7452–7453.
https://doi.org/10.1182/blood-2022-167053
Published: 2022
Journal Articles

Safety and Efficacy of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)

Free
Claire Roddie, Juliana Dias, Maeve A O'Reilly, Amaia Cadinanos Garai, Louisa Green, Mahnaz Abbasian, Marina Mitsikakou, Mhairi Vaughan, Vitoria Meyer Cantinho Pereira, Maria A V Marzolini, Leigh Wood, Joanna Olejnik, Yenting Ngai, Bilyana Popova, William Wilson, Victoria Spanswick, Helen Lowe, Leah Ensell, John A. Hartley, Farzin Farzaneh, Mark W. Lowdell, David C. Linch, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2021) 138 (Supplement 1): 3823.
https://doi.org/10.1182/blood-2021-146316
Published: 2021
Journal Articles

ALLCAR19: Updated Data Using AUTO1, a Novel Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies

Free
Claire Roddie, PhD MD, Maeve A O'Reilly, MBBCHBAO, Maria A V Marzolini, Leigh Wood, BA, Juliana Dias, Amaia Cadinanos Garai, BSc MSc, Leticia Bosshard, Mahnaz Abbasian, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Graham Wheeler, Joanna Olejnik, Bilyana Popova, MSc, Laura Clifton-Hadley, PhDBSc, Yashma Pathak, Victoria Spanswick, Helen Lowe, John A. Hartley, PhD, Farhatullah Syed, Waseem Qasim, MBBS, PhD, Farzin Farzaneh, PhD, David C. Linch, Martin Pule, MDPhD, Karl S Peggs, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-137768
Published: 2020
Journal Articles

Automated Manufacture of Matched Donor-Derived Allogeneic CD19 CAR T-Cells for Relapsed/Refractory B-ALL Following Allogeneic Stem Cell Transplantation: Toxicity, Efficacy and the Important Role of Lymphodepletion

Free
Claire Roddie, PhD MD, Maeve A O'Reilly, MBBCHBAO, Maria A V Marzolini, Leigh Wood, BA, Juliana Dias Alves Pinto, PhD, Mahnaz Abbasian, Ketki Vispute, Leticia Bosshard, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Graham Wheeler, Alex Day, Bilyana Popova, Kim Champion, Yashma Pathak, Alexia Gali, Nasir Mahmoud, Victoria Spanswick, Helen Lowe, John A. Hartley, PhD, Farzin Farzaneh, PhD, Lauren Nickolay, PhD, Fahetullah Syed, Waseem Qasim, MBBS, PhD, David C. Linch, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2019) 134 (Supplement_1): 776.
https://doi.org/10.1182/blood-2019-129640
Published: 2019
Journal Articles

AUTO1, a Novel Fast Off CD19CAR Delivers Durable Remissions and Prolonged CAR T Cell Persistence with Low CRS or Neurotoxicity in Adult ALL

Free
Claire Roddie, PhD MD, Maeve A O'Reilly, MBBCHBAO, Maria A V Marzolini, Leigh Wood, BA, Juliana Dias Alves Pinto, PhD, Mahnaz Abbasian, Ketki Vispute, Mark W. Lowdell, BSc, MSc, PhD FRCPath, Graham Wheeler, Joanna Olejnik, Bilyana Popova, Kim Champion, Alexia Gali, Yashma Pathak, Victoria Spanswick, Helen Lowe, John A. Hartley, PhD, Farzin Farzaneh, PhD, David C. Linch, Martin Pule, Karl S Peggs
Journal: Blood
Blood (2019) 134 (Supplement_1): 226.
https://doi.org/10.1182/blood-2019-131086
Published: 2019