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David Irvine
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Journal Articles

Long-Term Efficacy and Safety of Obecabtagene Autoleucel (obe-cel) in Adult Patients (pts) with Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia ([R/R B-ALL]; Pooled Analysis from ALLCAR19 and FELIX Phase Ib Studies) or Other B-cell Malignancies (ALLCAR19 Extension Study)

Claire Roddie, Eleni Tholouli, Paul Shaughnessy, Elias Jabbour, Aaron C. Logan, Katharine Hodby, Luke Mountjoy, Adrian John Clifton Bloor, David Irvine, David C. Linch, Kim H. Orchard, William Wilson, Bilyana Popova, Juliana Dias, Giulia Agliardi, Victoria Spanswick, Helen Lowe, Marina Mitsikakou, Eftychia Charalambous, Joanna Dawes, Meera Raymond, Yanqing Hu, Wolfram Brugger, Martin A. Pule, Jae H. Park, Karl Peggs
Journal: Blood
Blood (2023) 142 (Supplement 1): 2114.
https://doi.org/10.1182/blood-2023-180666
Published: 2023
Journal Articles

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma

Clinical Trials & Observations
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G. R. Peddareddigari, Nushmia Khokhar, Robert Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve A. O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin A. Pule
Journal: Blood
Blood (2023) 141 (20): 2470–2482.
https://doi.org/10.1182/blood.2022018598
Published: 2023
Includes: Supplemental data
Journal Articles

RAD52-Dependent Synthetic Lethality Eradicates Leukemia Stem Cells

Kimberly Cramer, Ph.D., Margaret Nieborowska-Skorska, MD, PhD, Artur Slupianek, PhD, Tomasz Sliwinski, David Irvine, Mhairi Copland, PhD, BSc, MRCP, FRCPath, Tomasz Skorski, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3.
https://doi.org/10.1182/blood.V120.21.3.3
Published: 2012
Journal Articles

Inhibition of Chronic Myeloid Leukemia Stem Cells by the Combination of the Hedgehog Pathway Inhibitor LDE225 with Nilotinib

Bin Zhang, David Irvine, Yin Wei Ho, Silvia Buonamici, PhD, Paul Manley, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Mhairi Copland, PhD, BSc, MRCP, FRCPath, Ravi Bhatia, MD
Journal: Blood
Blood (2010) 116 (21): 514.
https://doi.org/10.1182/blood.V116.21.514.514
Published: 2010