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Journal Articles

Phenotypic shift from primitive to monocytic immunophenotype is unique to patients treated with azacitidine + venetoclax (AZA/VEN) and associated with worse outcomes in AML

Free
Daniel Peters, Diana Abbott, Jingjing Zhang, Jacob Fang, Zenggang Pan, Jeffrey Schowinsky, Jonathan Gutman, Andrew Kent, Mathew Angelos, Christine McMahon, Maria Amaya, Marc Schwartz, Wei Xie, Jonathan Galeotti, Jill Buss, Ann-Kathrin Eisfeld, Curtis Lachowiez, Joshua Zeidner, Daniel Pollyea
Journal: Blood
Blood (2025) 146 (Supplement 1): 3377.
https://doi.org/10.1182/blood-2025-3377
Published: 2025
Journal Articles

Analysis of CD8 cytotoxic t-cells in patients with myelodysplastic syndrome (MDS) and T-cell large granulocyte lymphocytic leukemia (T-LGLL) reveal a distinct phenotype compared to those with t-lgll

Free
Makenna May, Cassandra Duarte, Rosana Moreira Pereira, Jamie Borg, Kellen Gil, Monica Ransom, William Showers, Jingjing Zhang, Daniel Pollyea, Nathaly Limon De La Rosa, Bradley Haverkos, Austin Gillen, Carlo Marchetti, Maria Amaya
Journal: Blood
Blood (2025) 146 (Supplement 1): 5610.
https://doi.org/10.1182/blood-2025-5610
Published: 2025
Journal Articles

The prognostic significance (or lack) of achieving marrow complete remission (mCR) with hypomethylating agent-based therapy in patients with myelodysplastic syndrome

Free
Benjamin Rolles, Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Jessica Stempel, Luca Lanino, Najla Al Ali, Amy DeZern, Mikkael Sekeres, Geoffrey Uy, Samuel Urrutia, Hetty Carraway, Pinkal Desai, Elizabeth Griffiths, Eytan Stein, Andrew Brunner, Christine McMahon, Rory Shallis, Joshua Zeidner, Michael Savona, Namrata Chandhok, Constantine Logothetis, Aram Bidikian, Theodore Getz, Gail Roboz, Eunice Wang, Maria Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan Madanat, Yasmin Abaza, Talha Badar, Jaclynn Campos, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop Enjeti, Kamal Alrabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Matteo Della Porta, Rami Komrokji, Amer Zeidan, Maximilian Stahl
Journal: Blood
Blood (2025) 146 (Supplement 1): 3865.
https://doi.org/10.1182/blood-2025-3865
Published: 2025
Journal Articles

Clinical implications of TP53 mutations (TP53MT) in patients (pts) with higher risk Myelodysplastic Syndromes (HR-MDS) treated with hypomethylating agents (HMA) and allogeneic hematopoietic transplantation (allo-HCT): An analysis from the international consortium of MDS (icMDS) validate database

Free
Tariq Kewan, Jan Philipp Bewersdorf, Luca Lanino, Ondrej Blaha, Jessica Stempel, Najla Al Ali, Amy DeZern, Mikkael Sekeres, Geoffrey Uy, Samuel Urrutia, Hetty Carraway, Pinkal Desai, Elizabeth Griffiths, Eytan Stein, Andrew Brunner, Christine McMahon, Rory Shallis, Joshua Zeidner, Michael Savona, Namrata Chandhok, Constantine Logothetis, Aram Bidikian, Theodore Getz, Gail Roboz, Benjamin Rolles, Eunice Wang, Amyah Harris, Maria Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan Madanat, Yasmin Abaza, Talha Badar, Jaclynn Campos, Torsten Haferlach, Jaroslaw Maciejewski, Anoop Enjeti, Kamal Al-Rabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Rami Komrokji, Maximilian Stahl, Matteo Della Porta, David Sallman, Amer Zeidan
Journal: Blood
Blood (2025) 146 (Supplement 1): 3863.
https://doi.org/10.1182/blood-2025-3863
Published: 2025
Journal Articles

Next-generation sequencing (NGS) of DNA isolated from nail specimens and run in parallel with tumor NGS accurately and efficiently detects germline predisposition variants in myeloid malignancies

Free
Meredith Beaton, Michelle Springer, Cailin Collins, Mathew Angelos, Andrew Kent, Maria Amaya, Jonathan Gutman, Marc Schwartz, Danica Wiredja, Michael Clay, Alisa Gaskell, Nicholas Willard, Daniel Pollyea, Christine McMahon
Journal: Blood
Blood (2025) 146 (Supplement 1): 1084.
https://doi.org/10.1182/blood-2025-1084
Published: 2025
Journal Articles

Outcomes of patients (pts) with higher-risk myelodysplastic syndromes (HR-MDS) treated with hypomethylating agents (HMA) + venetoclax (VEN) – a large analysis from the international consortium for MDS (icMDS) validate database

Free
Jan Philipp Bewersdorf, Tariq Kewan, Luca Lanino, Wei Wei, Najla Al Ali, Amy DeZern, Mikkael Sekeres, Geoffrey Uy, Samuel Urrutia, Hetty Carraway, Pinkal Desai, Elizabeth Griffiths, Eytan Stein, Andrew Brunner, Christine McMahon, Rory Shallis, Joshua Zeidner, Michael Savona, Hayley Hawkins, Namrata Chandhok, Constantine Logothetis, Aram Bidikian, Theodore Getz, Gail Roboz, Benjamin Rolles, Eunice Wang, Amyah Harris, Maria Amaya, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan Madanat, Yasmin Abaza, Jaclynn Campos, Talha Badar, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop Enjeti, Kamal Alrabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Max Stahl, Matteo Della Porta, Rami Komrokji, Amer Zeidan
Journal: Blood
Blood (2025) 146 (Supplement 1): 606.
https://doi.org/10.1182/blood-2025-606
Published: 2025
Journal Articles

Patients with AML with an IDH2 R172K mutation have improved overall survival with venetoclax + azacitidine as compared to those with IDH2 R140Q mutations

Free
Allyson Freedy, Danica Wiredja, Jingjing Zhang, Christine McMahon, Mathew Angelos, Maria Amaya, Jonathan Gutman, Marc Schwartz, Daniel Pollyea, Andrew Kent
Journal: Blood
Blood (2025) 146 (Supplement 1): 7018.
https://doi.org/10.1182/blood-2025-7018
Published: 2025
Journal Articles

The impact of monocytic phenotype and NPM1-mutation status in Acute Myeloid Leukemia when treated with traditional induction chemotherapy compared to azacitidine and venetoclax

Free
Michael Jones, Cailin Collins, Danica Wiredja, Jingjing Zhang, Christine McMahon, Mathew Angelos, Maria Amaya, Jonathan Gutman, Marc Schwartz, Daniel Pollyea, Andrew Kent
Journal: Blood
Blood (2025) 146 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2025-3478
Published: 2025
Journal Articles

RNA fusion sequencing identifies clinically relevant and novel fusions with therapeutic implications in adults with Acute Myeloid Leukemia (AML)

Free
Christine McMahon, Mathew Angelos, Andrew Kent, Maria Amaya, Marc Schwartz, Jonathan Gutman, Michael Clay, Danica Wiredja, Nicholas Willard, Daniel Pollyea
Journal: Blood
Blood (2025) 146 (Supplement 1): 5287.
https://doi.org/10.1182/blood-2025-5287
Published: 2025
Journal Articles

UCD19 CAR-T cell therapy for adults with B-cell acute lymphoblastic leukemia in first complete remission with MRD positivity: Preliminary Results of A phase I/ib clincal trial

Free
Marc Schwartz, Navin Pinto, Michael Verneris, Daniel Pollyea, Christine McMahon, Jonathan Gutman, Angela Ohm, Maria Amaya, Andrew Kent, Mathew Angelos, Cheri Adams, Bonnie Yates, Katie Anttila, Jessica Dell-Martin, Kimberly Jordan, Terry Fry
Journal: Blood
Blood (2025) 146 (Supplement 1): 4165.
https://doi.org/10.1182/blood-2025-4165
Published: 2025
Journal Articles

Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells

Free
Maria Amaya, Megha Desai, Merlin Nithya Gnanapragasam, Shou Zhen Wang, Sheng Zu Zhu, David C. Williams, Jr, Gordon D. Ginder
Journal: Blood
Blood (2013) 121 (17): 3493–3501.
https://doi.org/10.1182/blood-2012-11-466227
Published: 2013
Includes: Supplemental data