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Amy DeZern
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Journal Articles

Evaluating large language models in real-world hematologic clinical decision-making: Performance, limitations, and clinical implications

Free
David Swoboda, Amy DeZern, James England, Sangeetha Venugopal, Thomas Kehoe, Brandon Aubrey, Marco Gabriele Raddi, Angela Consagra, Jiasheng Wang, Gustavo Rivero, Maximilian Stahl, Amer Zeidan, Torsten Haferlach, Andrew Brunner, Rena Buckstein, Valeria Santini, Matteo Della Porta, Mikkael Sekeres, Aziz Nazha
Journal: Blood
Blood (2025) 146 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2025-4349
Published: 2025
Journal Articles

Exposure to agent orange and risk of myelodysplastic syndromes

Free
Mikkael Sekeres, Amy DeZern, Michael Otterstatter, Eric Padron, Tareq Al Baghdadi, James Foran, Rami Komrokji, Gregory Abel, Wael Saber, Steven Gore, Cecilia Lee, Rafael Bejar, Jijun Liu, Joachim Deeg, Seth Sherman, R. Coleman Lindsley, Nancy DiFronzo, Matthew Walter, Nancy Gillis
Journal: Blood
Blood (2025) 146 (Supplement 1): 5626.
https://doi.org/10.1182/blood-2025-5626
Published: 2025
Journal Articles

A randomized, multicenter trial of shorter durations of hypomethylating agents in lower-risk Myelodysplastic Syndromes

Free
Ian Bouligny, Hetty Carraway, Mikkael Sekeres, Amy DeZern, Rami Komrokji, Richard Stone, Gail Roboz, Koji Sasaki, Guillermo Montalban-Bravo, Alex Bataller, Alexandre Bazinet, Danielle Hammond, Kelly Chien, Courtney DiNardo, Gautam Borthakur, Yesid Alvarado Valero, Farhad Ravandi, Naval Daver, Tapan Kadia, Naveen Pemmaraju, Nicholas Short, Jane Waukau, Matthew Rump, Colin Huck, Wei Qiao, Xuelin Huang, Elias Jabbour, Guillermo Garcia-Manero
Journal: Blood
Blood (2025) 146 (Supplement 1): 487.
https://doi.org/10.1182/blood-2025-487
Published: 2025
Journal Articles

Artificial intelligence‑driven virtual tumor board enhances precision care in myelodysplastic syndromes (MDS)

Free
David Swoboda, Amy DeZern, James England, Sangeetha Venugopal, Thomas Kehoe, Brandon Aubrey, Marco Gabriele Raddi, Angela Consagra, Jiasheng Wang, Gustavo Rivero, Maximilian Stahl, Amer Zeidan, Torsten Haferlach, Andrew Brunner, Rena Buckstein, Valeria Santini, Matteo Della Porta, Mikkael Sekeres, Aziz Nazha
Journal: Blood
Blood (2025) 146 (Supplement 1): 7363.
https://doi.org/10.1182/blood-2025-7363
Published: 2025
Journal Articles

Personalized Desensitization for DSAs in Allogeneic Blood or Marrow Transplantation: Impact on Graft Outcomes and Access to Transplant

Free
Christian Gocke, Marianna Zahurak, Ilias Sinanidis, Suraya Berger, Javier Bolanos-Meade, Ephraim Fuchs, Alex Ambinder, Philip Imus, Amy DeZern, Rick Jones, Ravi Varadhan, Maria Bettinotti
Journal: Blood
Blood (2025) 146 (Supplement 1): 510.
https://doi.org/10.1182/blood-2025-510
Published: 2025
Journal Articles

DNMT3A, NPM1, and FLT3-ITD triple-mutated AML has a favorable prognosis in the era of FLT3 inhibitors

Free
Shirley Mo, Alex Ambinder, Amy DeZern, B. Douglas Smith, Ephraim Fuchs, Gabriel Ghiaur, Gabrielle Prince, Ivana Gojo, Javier Bolanos-Meade, Jonathan Webster, Lukasz Gondek, Richard Jones, Tania Jain, Theodoros Karantanos, William Dalton, Mark Levis
Journal: Blood
Blood (2025) 146 (Supplement 1): 1710.
https://doi.org/10.1182/blood-2025-1710
Published: 2025
Journal Articles

Post-allogeneic hematopoietic cell transplantation outcomes are similar after hypomethylating agent/venetoclax and intensive, cytarabine-based remission induction for Acute Myeloid Leukemia when using standardized, contemporary transplant techniques

Free
John Claiborne, Venkata Preetam Sandeep Kaduluri, Hua-Ling Tsai, Ivana Gojo, Amy DeZern, B. Douglas Smith, Tania Jain, Gabrielle Prince, Javier Bolanos-Meade, Ephraim Fuchs, Gabriel Ghiaur, Lukasz Gondek, William Dalton, Theodoros Karantanos, Ravi Varadhan, Mark Levis, Richard Jones, Jonathan Webster, Alex Ambinder
Journal: Blood
Blood (2025) 146 (Supplement 1): 44.
https://doi.org/10.1182/blood-2025-44
Published: 2025
Journal Articles

Artificial intelligence-based diagnosis of myelodysplastic syndromes/neoplasms using bone marrow

Free
Palak Dave, Ling Zhang, Joseph Pierce, Sameer Andani, Jordan Rai, Mohammad Hussaini, Mary Ellen Walker, Nancy Gillis, Lynn Moscinski, Mikkael Sekeres, Amy DeZern, Eric Padron, Rami Komrokji, Issam El Naqa
Journal: Blood
Blood (2025) 146 (Supplement 1): 5642.
https://doi.org/10.1182/blood-2025-5642
Published: 2025
Journal Articles

The prognostic significance (or lack) of achieving marrow complete remission (mCR) with hypomethylating agent-based therapy in patients with myelodysplastic syndrome

Free
Benjamin Rolles, Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Jessica Stempel, Luca Lanino, Najla Al Ali, Amy DeZern, Mikkael Sekeres, Geoffrey Uy, Samuel Urrutia, Hetty Carraway, Pinkal Desai, Elizabeth Griffiths, Eytan Stein, Andrew Brunner, Christine McMahon, Rory Shallis, Joshua Zeidner, Michael Savona, Namrata Chandhok, Constantine Logothetis, Aram Bidikian, Theodore Getz, Gail Roboz, Eunice Wang, Maria Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan Madanat, Yasmin Abaza, Talha Badar, Jaclynn Campos, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop Enjeti, Kamal Alrabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Matteo Della Porta, Rami Komrokji, Amer Zeidan, Maximilian Stahl
Journal: Blood
Blood (2025) 146 (Supplement 1): 3865.
https://doi.org/10.1182/blood-2025-3865
Published: 2025
Journal Articles

Clinical implications of TP53 mutations (TP53MT) in patients (pts) with higher risk Myelodysplastic Syndromes (HR-MDS) treated with hypomethylating agents (HMA) and allogeneic hematopoietic transplantation (allo-HCT): An analysis from the international consortium of MDS (icMDS) validate database

Free
Tariq Kewan, Jan Philipp Bewersdorf, Luca Lanino, Ondrej Blaha, Jessica Stempel, Najla Al Ali, Amy DeZern, Mikkael Sekeres, Geoffrey Uy, Samuel Urrutia, Hetty Carraway, Pinkal Desai, Elizabeth Griffiths, Eytan Stein, Andrew Brunner, Christine McMahon, Rory Shallis, Joshua Zeidner, Michael Savona, Namrata Chandhok, Constantine Logothetis, Aram Bidikian, Theodore Getz, Gail Roboz, Benjamin Rolles, Eunice Wang, Amyah Harris, Maria Amaya, Hayley Hawkins, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan Madanat, Yasmin Abaza, Talha Badar, Jaclynn Campos, Torsten Haferlach, Jaroslaw Maciejewski, Anoop Enjeti, Kamal Al-Rabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Rami Komrokji, Maximilian Stahl, Matteo Della Porta, David Sallman, Amer Zeidan
Journal: Blood
Blood (2025) 146 (Supplement 1): 3863.
https://doi.org/10.1182/blood-2025-3863
Published: 2025
Journal Articles

Wide variability and inconsistency in reporting of results of Myelodysplastic Syndromes/neoplasms (MDS) clinical trials: An icMDS systematic review of published manuscripts

Free
Ted Getz, Kelly Pugh, Andrew Brunner, Jan Philipp Bewersdorf, Amy DeZern, Tariq Kewan, Uma Borate, Uwe Platzbecker, Mikkael Sekeres, Andrew Wei, Shahram Kordasti, Rena Buckstein, Gail Roboz, Michael Savona, Sanam Loghavi, Robert Hasserjian, Pierre Fenaux, David Sallman, Christopher Hourigan, Matteo Della Porta, Stephen Nimer, Richard Little, Valeria Santini, Fabio Efficace, Justin Taylor, Olatoyosi Odenike, Tae Kon Kim, Stephanie Halene, Rami Komrokji, Elizabeth Griffiths, Peter Greenberg, Mina Xu, Zhuoer Xie, Rafael Bejar, Guillermo Sanz, Mrinal Patnaik, Maria E. Figueroa, Hetty Carraway, Omar Abdel-Wahab, Daniel Starczynowski, Eric Padron, Jacqueline Boultwood, Steven Gore, Naval Daver, Jane Churpek, Ravi Majeti, John Bennett, Alan List, Adrian Mosquera Orgueira, Klaus Metzeler, Francesc Sole, Lisa Pleyer, Arjan Van de Loosdrecht, Thomas Cluzeau, David Steensma, Ghulam Mufti, Lionel Ades, Luca Lanino, Yazan Madanat, Anne Sophie Kubasch, Marie Sebert, R. Coleman Lindsley, Katharina S. Götze, Carmelo Gurnari, Yasushi Miyazaki, Aref Al-Kali, Abdulraheem Yacoub, Bing Li, Ioannis Kotsianidis, Maximilian Stahl, Amer Zeidan
Journal: Blood
Blood (2025) 146 (Supplement 1): 3852.
https://doi.org/10.1182/blood-2025-3852
Published: 2025
Journal Articles

Clinical, genetic, and pathologic differences across race, ethnicity, and sex in patients with MDS and precursor conditions from the national MDS natural history study

Free
Nancy Gillis, Christelle Colin-Leitzinger, Yi-Han Tang, Michael Otterstatter, Seth Sherman, Ling Zhang, Lynn Moscinski, Mary Ellen Walker, Jeffrey Painter, Gregory Abel, Tareq Al Baghdadi, Rafael Bejar, James Foran, Steven Gore, Alexandra Harrington, Steven Kroft, Jijun Liu, Wael Saber, Rami Komrokji, Eric Padron, Nancy DiFronzo, Matthew Walter, Amy DeZern, Mikkael Sekeres
Journal: Blood
Blood (2025) 146 (Supplement 1): 3845.
https://doi.org/10.1182/blood-2025-3845
Published: 2025
Journal Articles

5-azacytidine treatment reshapes clonal structure and alters mutation-dependent splicing in MDS patients

Free
Xuan Zhang, Mutian Tang, Guangyuan Li, David Bernardicius, Jennifer VanOudenhove, Amy DeZern, Gabriel Ghiaur, Stephanie Halene, Nathan Salomonis, H. Leighton Grimes
Journal: Blood
Blood (2025) 146 (Supplement 1): 2054.
https://doi.org/10.1182/blood-2025-2054
Published: 2025
Journal Articles

Metronomic dose decitabine therapy for TP53 complex karyotype myeloid neoplasms

Free
Laura Walsh, Venkata Preetam Sandeep Kaduluri, Amy DeZern, Gabrielle Prince, Jonathan Webster, Tania Jain, Theodoros Karantanos, William Dalton, Ivana Gojo, Alex Ambinder, B. Douglas Smith, Lukasz Gondek, Mark Levis, Gabriel Ghiaur
Journal: Blood
Blood (2025) 146 (Supplement 1): 5227.
https://doi.org/10.1182/blood-2025-5227
Published: 2025
Journal Articles

A multi-site break through cancer pilot study testing the feasibility and safety of therapeutic intervention for patients with high-risk clonal cytopenia of undetermined significance (CCUS)

Free
Danielle Hammond, Amy DeZern, Kelly Chien, Sanam Loghavi, Geoffrey Fell, Darren Evanchuk, Eytan Stein, Sam Sadigh, Rena Xian, Wenbin Xiao, Guillermo Garcia-Manero, Max Stahl, Lachelle Weeks
Journal: Blood
Blood (2025) 146 (Supplement 1): 3160.
https://doi.org/10.1182/blood-2025-3160
Published: 2025
Journal Articles

Outcomes of patients (pts) with higher-risk myelodysplastic syndromes (HR-MDS) treated with hypomethylating agents (HMA) + venetoclax (VEN) – a large analysis from the international consortium for MDS (icMDS) validate database

Free
Jan Philipp Bewersdorf, Tariq Kewan, Luca Lanino, Wei Wei, Najla Al Ali, Amy DeZern, Mikkael Sekeres, Geoffrey Uy, Samuel Urrutia, Hetty Carraway, Pinkal Desai, Elizabeth Griffiths, Eytan Stein, Andrew Brunner, Christine McMahon, Rory Shallis, Joshua Zeidner, Michael Savona, Hayley Hawkins, Namrata Chandhok, Constantine Logothetis, Aram Bidikian, Theodore Getz, Gail Roboz, Benjamin Rolles, Eunice Wang, Amyah Harris, Maria Amaya, Somedeb Ball, Justin Grenet, Zhuoer Xie, Yazan Madanat, Yasmin Abaza, Jaclynn Campos, Talha Badar, Torsten Haferlach, Jaroslaw Maciejewski, David Sallman, Anoop Enjeti, Kamal Alrabi, Khalid Halahleh, Devendra Hiwase, Maria Diez-Campelo, David Valcarcel, Claudia Haferlach, Lisa Pleyer, Ioannis Kotsianidis, Vassiliki Pappa, Valeria Santini, Angela Consagra, Aref Al-Kali, Seishi Ogawa, Yasuhito Nannya, Max Stahl, Matteo Della Porta, Rami Komrokji, Amer Zeidan
Journal: Blood
Blood (2025) 146 (Supplement 1): 606.
https://doi.org/10.1182/blood-2025-606
Published: 2025
Journal Articles

Clinical-genomic profiling of MDS to inform allo-HCT: recommendations from an international panel on behalf of the EBMT

Free
Carmelo Gurnari, Marie Robin, Lionel Adès, Mahmoud Aljurf, Antonio Almeida, Fernando Barroso Duarte, Elsa Bernard, Corey Cutler, Matteo Giovanni Della Porta, Theo De Witte, Amy DeZern, Joanna Drozd-Sokolowska, Eric Duncavage, Pierre Fenaux, Nico Gagelmann, Guillermo Garcia-Manero, Claudia Haferlach, Torsten Haferlach, Robert Hasserjian, Eva Hellström-Lindberg, Meagan Jacoby, Austin Kulasekararaj, R. Coleman Lindsley, Jaroslaw P. Maciejewski, Hideki Makishima, Luca Malcovati, Moshe Mittelman, Anders E. Myhre, Seishi Ogawa, Francesco Onida, Elli Papaemmanuil, Jakob Passweg, Uwe Platzbecker, Lisa Pleyer, Kavita Raj, Valeria Santini, Anna Sureda, Magnus Tobiasson, Maria Teresa Voso, Ibrahim Yakoub-Agha, Amer Zeidan, Matthew Walter, Nicolaus Kröger, Donal P. McLornan, Mario Cazzola
Journal: Blood
Blood (2025) 145 (18): 1987–2001.
https://doi.org/10.1182/blood.2024025131
Published: 2025
Includes: Supplemental data
Journal Articles

Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN

Free
Clinical Trials & Observations
Elias Jabbour, Nicholas J. Short, Guillermo Montalban-Bravo, Xuelin Huang, Carlos Bueso-Ramos, Wei Qiao, Hui Yang, Chong Zhao, Tapan Kadia, Gautam Borthakur, Naveen Pemmaraju, Koji Sasaki, Zeev Estrov, Jorge Cortes, Farhad Ravandi, Yesid Alvarado, Rami Komrokji, Mikkael A. Sekeres, David P. Steensma, Amy DeZern, Gail Roboz, Hagop Kantarjian, Guillermo Garcia-Manero
Journal: Blood
Blood (2017) 130 (13): 1514–1522.
https://doi.org/10.1182/blood-2017-06-788497
Published: 2017
Includes: Supplemental data