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Journal Articles

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

Sandra M. Dold, MSc, BSc, Veronika Riebl, Dagmar Wider, Marie Follo, PhD, Stefan J. Mueller, Ingrid Bartsch, Milena Pantic, PhD, Cornelius Miething, MD, Chrissoula Kiote-Schmidt, K. Martin Kortüm, MD, Mihaela Zlei, Abdel Kareem Azab, PhD, Mascha Binder, MD, Justyna Rawluk, Justus Duyster, Prof., Robert Zeiser, MD, Ralph Wäsch, MD, Monika Engelhardt, MD

Blood (2018) 132 (Supplement 1): 3222.

https://doi.org/10.1182/blood-2018-99-112489

Published: 2018

Journal Articles

Epigenetic Modifications of the Bone Marrow (BM) Niche in Multiple Myeloma (MM) - a Three-Dimensional (3D) in Vitro Approach

Stefan J. Müller, PharmD, Dagmar Wider, Andreas R. Thomsen, MD, Marie Follo, PhD, Johannes M. Waldschmidt, MD, Gabriele Ihorst, Sandra M. Dold, MSc, Julia Felthaus, Johanna Senger, PhD, Julia Schüler, DVM, Justus Duyster, Abdel Kareem Azab, PhD, Martin J. Hug, PhD, Manfred Jung, PhD, Ralph Wäsch, MD, Monika Engelhardt

Blood (2017) 130 (Supplement 1): 1793.

https://doi.org/10.1182/blood.V130.Suppl_1.1793.1793

Published: 2017

Journal Articles

PIM1-Mediated CXCR4 Phosphorylation: A Potentially Class-Distinct Therapeutic Target of Next Generation Proteasome Inhibitors in Multiple Myeloma

Johannes M. Waldschmidt, MD, Dagmar Wider, Stefan J. Müller, Dipl.-Pharm., Anna Simon, Sarah Decker, PhD, Marie Follo, PhD, Justus Duyster, MD PhD, Ralph Wäsch, MD, Monika Engelhardt, MD PhD

Blood (2016) 128 (22): 2774.

https://doi.org/10.1182/blood.V128.22.2774.2774

Published: 2016

Journal Articles

The APC/C Coactivator Cdh1 Controls Self-Renewal and Differentiation of Human and Murine HSPCs

Daniel Ewerth, Stefanie Kreutmair, Andrea Schmidts, Marie Follo, PhD, Dagmar Wider, Julia B. Schueler, DVM, PhD, Julia Felthaus, Justus Duyster, MD, Anna Lena Illert, MD, Monika Engelhardt, MD PhD, Wäsch Ralph, MD

Blood (2016) 128 (22): 2650.

https://doi.org/10.1182/blood.V128.22.2650.2650

Published: 2016

Journal Articles

PIM1 Inhibition Enhances and Prolongs Plerixafor-Induced Mobilization of HSCs

Tony Andreas Müller, PhD, Anabel Zwick, Sarah Decker, PhD, Claudius Klein, PhD, Benjamin Rister, MD, Alina Rudorf, Sandra Kissel, Marie Follo, PhD, Ralph Wäsch, MD, Anna Lena Illert, MD, Claudia Waskow, PhD, Christine Dierks, MD, Justus Duyster, MD

Blood (2016) 128 (22): 655.

https://doi.org/10.1182/blood.V128.22.655.655

Published: 2016

Journal Articles

Depletion of Ptch2 Activates Canonical and Non-Canonical HH Signaling within the Niche Leading to Myeloproliferation, Stem Cell Exhaustion and Accelerates JAK2V617F Driven Disease

Claudius Klein, Anabel Kuhn, Sandra Kissel, Marie Follo, PhD, Anna Lena Illert, MD, Dietmar Pfeifer, Heike L Pahl, PhD, Robert A.J. Oostendorp, PhD, Justus Duyster, MD, Christine Dierks, MD

Blood (2015) 126 (23): 3593.

https://doi.org/10.1182/blood.V126.23.3593.3593

Published: 2015

Journal Articles

Mimicking the Myeloma Niche: A 3D Bone-Derived Co-Culture System to Selectively Assess Bystander BMSCs and to Perform High-Throughput Drug Screening in Multiple Myeloma

Johannes M. Waldschmidt, MD, Dagmar Wider, Andreas R. Thomsen, MD, Claudius Klein, Christine Aldrian, Martin Kortuem, MD, Marie Follo, PhD, Julia Schüler, DVM, PhD, Justus Duyster, MD PhD, Monika Engelhardt, MD PhD, Ralph Wäsch, MD PhD

Blood (2015) 126 (23): 1822.

https://doi.org/10.1182/blood.V126.23.1822.1822

Published: 2015

Journal Articles

Investigation of the CXCL12-CXCR4/CXCR7 Axis in Multiple Myeloma (MM): Adhesion Molecules As Novel Targets of the Potent Proteasome Inhibitor Carfilzomib

Anna Simon, Dagmar Wider, Johannes Waldschmidt, MD, Marie Follo, PhD, Sarah Decker, PhD, Ralph Wäsch, MD, Monika Engelhardt, MD

Blood (2014) 124 (21): 927.

https://doi.org/10.1182/blood.V124.21.927.927

Published: 2014

Journal Articles

MiR-146a Regulates the TRAF6/TNF-Axis in Donor T Cells during Graft-Versus-Host Disease

Natalie Stickel, MS, Gabriele Prinz, Dietmar Pfeifer, PhD, Annette Schmitt-Graeff, MD, Marie Follo, PhD, Jürgen Finke, Justus Duyster, MD, Ulrich Salzer, MD, Robert Zeiser

Blood (2014) 124 (21): 843.

https://doi.org/10.1182/blood.V124.21.843.843

Published: 2014

Journal Articles

Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis

Blood (2014) 124 (21): 844.

https://doi.org/10.1182/blood.V124.21.844.844

Published: 2014

Journal Articles

Bone Marrow Interaction and Multiple Myeloma - Approximating Reality in Novel High-Throughput Multiple Myeloma Coculture Systems

Johannes Waldschmidt, MD, Dagmar Wider, Anna Simon, Andreas R. Thomsen, MD, Christine Aldrian, Marie Follo, PhD, Julia Schüler, Martin Kortum, MD, Ralph Wäsch, MD, Monika Engelhardt, MD

Blood (2014) 124 (21): 2243.

https://doi.org/10.1182/blood.V124.21.2243.2243

Published: 2014

Journal Articles

Targeting The Protective Microenvironment In Multiple Myeloma (MM): An Analysis Of The CXCL12/CXCR4-Axis and Its Inhibitors AMD3100 and Nox-A12 Combined With Antimyeloma Substances, Such As Pomalidomide and Carfilzomib

Anna Simon, Dagmar Wider, Marie Follo, PhD, Johannes Waldschmidt, Martina Kleber, Ralph Waesch, MD, Monika Engelhardt, MD

Blood (2013) 122 (21): 3851.

https://doi.org/10.1182/blood.V122.21.3851.3851

Published: 2013

Journal Articles

Bone Marrow Interaction in Multiple Myeloma Pathogenesis: Phenotypical Analysis, Kinetics and Novel Therapy Approaches Based On CXCR4 Inhibition.

Johannes Waldschmidt, Dagmar Wider, Marie Follo, PhD, Josefina Udi, MD, Martina Kleber, Joschka Lorenz, Gabriele Ihorst, Ralph Wäsch, Monika Engelhardt

Blood (2012) 120 (21): 2450.

https://doi.org/10.1182/blood.V120.21.2450.2450

Published: 2012

Journal Articles

Multikinase Inhibitor Sorafenib Induces Apoptosis, CD138-Downregulation, Actin Depolymerization and Inhibition of M210B4-Triggered Chemotaxis in Multiple Myeloma Cell Lines and Synergyzes with Proteasome Inhibitor Bortezomib

Josefina Udi, MD, Dagmar Wider, Julie Catusse, PhD, Dominik Schnerch, MD, Marie Follo, PhD, Gabriele Ihorst, Ralph Waesch, MD, Monika Engelhardt, MD

Blood (2011) 118 (21): 2380.

https://doi.org/10.1182/blood.V118.21.2380.2380

Published: 2011

Journal Articles

The Spindle Checkpoint Protein BubR1 Is Differentially Expressed in the Lymphatic and Myeloid Lineage and Is a Determinator of Response to Spindle Poisons

Dominik Schnerch, MD, Marie Follo, PhD, Andrea Schmidts, Julika Krohs, Julia Felthaus, Monika Engelhardt, MD, Ralph Wäsch

Blood (2011) 118 (21): 1407.

https://doi.org/10.1182/blood.V118.21.1407.1407

Published: 2011

Journal Articles

Deficiency of CD73/Ecto-5'-Nucleotidase Enhances Acute Graft-Versus-Host Disease

Petya Chernogorova, Hiroki Tsukamoto, Ph.D., Korcan Ayata, Ph.D., Ulrike V. Gerlach, M.D., Ankur Rughani, Jayanthi Ganesan, Marie Follo, PhD, Linda F. Thompson, Ph.D., Marco Idzko, M.D., Robert Zeiser, M.D.

Blood (2011) 118 (21): 312.

https://doi.org/10.1182/blood.V118.21.312.312

Published: 2011

Journal Articles

Distinct Patterns of Systemic Immune Dysregulation in Indolent B Cell Lymphoma

Petros Christopoulos, MD, Dietmar Pfeifer, PhD, Kilian Bartholomé, PhD, Marie Follo, PhD, Paul Fisch, MD, Jens Timmer, PhD, Hendrik Veelken, MD

Blood (2008) 112 (11): 3780.

https://doi.org/10.1182/blood.V112.11.3780.3780

Published: 2008

NARROW

Minimal Residual Disease (MRD) Analysis Using Multiparametric Flow Cytometry (MFC) and Identification of Differences in Subpopulations Using Next Generation Sequencing (NGS) in the Bone Marrow (BM) of Multiple Myeloma (MM) Patients (pts)

Epigenetic Modifications of the Bone Marrow (BM) Niche in Multiple Myeloma (MM) - a Three-Dimensional (3D) in Vitro Approach

PIM1-Mediated CXCR4 Phosphorylation: A Potentially Class-Distinct Therapeutic Target of Next Generation Proteasome Inhibitors in Multiple Myeloma

The APC/C Coactivator Cdh1 Controls Self-Renewal and Differentiation of Human and Murine HSPCs

PIM1 Inhibition Enhances and Prolongs Plerixafor-Induced Mobilization of HSCs

Depletion of Ptch2 Activates Canonical and Non-Canonical HH Signaling within the Niche Leading to Myeloproliferation, Stem Cell Exhaustion and Accelerates JAK2V617F Driven Disease

Mimicking the Myeloma Niche: A 3D Bone-Derived Co-Culture System to Selectively Assess Bystander BMSCs and to Perform High-Throughput Drug Screening in Multiple Myeloma

Investigation of the CXCL12-CXCR4/CXCR7 Axis in Multiple Myeloma (MM): Adhesion Molecules As Novel Targets of the Potent Proteasome Inhibitor Carfilzomib

MiR-146a Regulates the TRAF6/TNF-Axis in Donor T Cells during Graft-Versus-Host Disease

Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis

Bone Marrow Interaction and Multiple Myeloma - Approximating Reality in Novel High-Throughput Multiple Myeloma Coculture Systems

Targeting The Protective Microenvironment In Multiple Myeloma (MM): An Analysis Of The CXCL12/CXCR4-Axis and Its Inhibitors AMD3100 and Nox-A12 Combined With Antimyeloma Substances, Such As Pomalidomide and Carfilzomib

Bone Marrow Interaction in Multiple Myeloma Pathogenesis: Phenotypical Analysis, Kinetics and Novel Therapy Approaches Based On CXCR4 Inhibition.

Multikinase Inhibitor Sorafenib Induces Apoptosis, CD138-Downregulation, Actin Depolymerization and Inhibition of M210B4-Triggered Chemotaxis in Multiple Myeloma Cell Lines and Synergyzes with Proteasome Inhibitor Bortezomib

The Spindle Checkpoint Protein BubR1 Is Differentially Expressed in the Lymphatic and Myeloid Lineage and Is a Determinator of Response to Spindle Poisons

Deficiency of CD73/Ecto-5'-Nucleotidase Enhances Acute Graft-Versus-Host Disease

Distinct Patterns of Systemic Immune Dysregulation in Indolent B Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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