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Journal Articles

Chronic TNF in the Aging Microenvironment Exacerbates TET2- loss-of-Function Myeloid Expansion

Candice Quin, Erica DeJong, Amy J. M. McNaughton, Marco M. Buttigieg, Salman Basrai, Sagi Abelson, Margaret Larche, Michael J. Rauh, Dawn ME Bowdish

Blood (2023) 142 (Supplement 1): 938.

https://doi.org/10.1182/blood-2023-189163

Published: 2023

Journal Articles

The Impact of Clonal Hematopoiesis on Clinical Outcomes and Clonal Dynamics in Older Lymphoma Patients Receiving Chemotherapy

Rena Buckstein, Olivia Lopes, Amy J. M. McNaughton, Matthew C. Cheung, Lee Mozessohn, Lisa Chodirker, Kevin Imrie, Neil Berinstein, Signy Chow, Gillian Kupakuwana-Suk, Anne Parmentier, Prasha Sasitharakumar, Hubert Tsui, Liying Zhang, Michael J. Rauh

Blood (2023) 142 (Supplement 1): 442.

https://doi.org/10.1182/blood-2023-187778

Published: 2023

Journal Articles

Transcriptomic Analysis of Clonal Hematopoiesis in Solid Tumors Reveals Driver Mutation-Specific Patterns of Immune Dysregulation

Marco M. Buttigieg, Caitlyn Vlasschaert, Michael J. Rauh

Blood (2023) 142 (Supplement 1): 4060.

https://doi.org/10.1182/blood-2023-190081

Published: 2023

Journal Articles

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets

Caitlyn Vlasschaert, Taralynn Mack, J. Brett Heimlich, Abhishek Niroula, Md Mesbah Uddin, Joshua Weinstock, Brian Sharber, Alexander J. Silver, Yaomin Xu, Michael Savona, Christopher Gibson, Matthew B. Lanktree, Michael J. Rauh, Benjamin L. Ebert, Pradeep Natarajan, Siddhartha Jaiswal, Alexander G. Bick

Blood (2023) 141 (18): 2214–2223.

https://doi.org/10.1182/blood.2022018825

Published: 2023

Includes: Supplemental data

Journal Articles

Breaking the CH inflammation-expansion cycle

Michael J. Rauh

Blood (2023) 141 (8): 815–816.

https://doi.org/10.1182/blood.2022019104

Published: 2023

Journal Articles

DNA Methylation Profiles Capture Clinical and Molecular Heterogeneity of MDS and Can be Harnessed for the Development of Robust Biomarkers Predictive of Response to Azacitidine

Qin Yang, Alice Brogi, Elizabeth A. Griffiths, Matilde Y Follo, Carlo Finelli, Jerald P. Radich, Michael J Rauh, Mikkael A. Sekeres, Rafael Bejar, Valeria Santini, Maria Ken E. Figueroa

Blood (2022) 140 (Supplement 1): 9769–9770.

https://doi.org/10.1182/blood-2022-163704

Published: 2022

Journal Articles

CCUS and Low-Risk MDS Are Inherently Similar, Sharing Clonal and Clinical Features

Christina K Ferrone, Amy JM McNaughton, Iran Rashedi, Rena Buckstein, Hubert Tsui, Michael J Rauh

Blood (2022) 140 (Supplement 1): 6915–6916.

https://doi.org/10.1182/blood-2022-169710

Published: 2022

Journal Articles

Dynamic Stromal Changes in Myelofibrosis Patients Pre/Post JAK Inhibition Is Revealed in Clinically Archived Bone Marrow Biopsies By Smooth Muscle Actin (SMA)-CD34 Dual Immunohistochemistry

Katelyn Wang, Iran Rashedi, James T. England, Rashmi S. Goswami, Larissa Liontos, Raheem Peerani, Anne Tierens, Michael J Rauh, Vikas Gupta, Hubert Tsui

Blood (2021) 138 (Supplement 1): 3286.

https://doi.org/10.1182/blood-2021-151458

Published: 2021

Journal Articles

Impact of Tet2 Deficiency, and of TET2 Mutations in Clonal Hematopoiesis, on Neutrophil/Granulocyte Immune Function

Elina K Cook, Michael Luo, Jeffrey Mewburn, Kimberly J Dunham-Snary, Charles Hindmarch, Stephen L Archer, Michael J Rauh

Blood (2021) 138 (Supplement 1): 2159.

https://doi.org/10.1182/blood-2021-147095

Published: 2021

Journal Articles

Clinical Utility of Hematopathologist-Triaged NGS Testing When Investigating Patients with Suspected MDS

Christina K Ferrone, Amy JM McNaughton, Iran Rashedi, Hubert Tsui, Michael J Rauh

Blood (2021) 138 (Supplement 1): 4675.

https://doi.org/10.1182/blood-2021-153594

Published: 2021

Journal Articles

RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

Elina K Cook, MSc, Richard N Armstrong, PhD, Eshita Sharma, PhD, Brooke Snetsinger, MSc, Jacqueline Boultwood, PhD, Rena Buckstein, MD FRCPC, Andrea Pellagatti, PhD, Michael J. Rauh, MD PhD

Blood (2018) 132 (Supplement 1): 3843.

https://doi.org/10.1182/blood-2018-99-116128

Published: 2018

Journal Articles

Validation and Clinical Impact of the Oncomine Myeloid Targeted DNA and RNA Ion Semiconductor Sequencing Assay

Christina Ferrone, BScH, Henry Wong, PhD, Laura Semenuk, Brooke Snetsinger, MSc, Xiao Zhang, David Good, MD FRCPC, Graeme Quest, MSc, MD FRCPC, Harriet Feilotter, PhD FCCMG, FACMG, Michael J. Rauh, MD PhD

Blood (2018) 132 (Supplement 1): 5523.

https://doi.org/10.1182/blood-2018-99-116576

Published: 2018

Journal Articles

Somatic Mutations Associated with Myeloid Transformation of RUNX1 -Mutated Familial Platelet Disorders with Propensity to Myeloid Malignancies Using Targeted Next-Generation Sequencing

Bruno K L Duarte, Samuel S Medina, MD, Gabriela G Yamaguti Hayakawa, MD, Fernando Ferreira Costa, MD PhD, Michael J. Rauh, MD PhD, Margareth C Ozelo, MD PhD

Blood (2017) 130 (Supplement 1): 2482.

https://doi.org/10.1182/blood.V130.Suppl_1.2482.2482

Published: 2017

Journal Articles

Feeding the Fire: The Comorbid and Inflammatory Backdrop of Clonal Hematopoiesis of Indeterminate Potential (CHIP) By Mutation Subtype

Elina K Cook, Terumi Izukawa, Sherylan Young, Gili Rosen, Mina Jamali, Brooke Snetsinger, Dylan Johnson, Eva Bain, Jamie Hilland, Jonah Buckstein, Janika Francis, Bushra Momtaz, Rena Buckstein, MD, Michael J. Rauh, MD PhD

Blood (2017) 130 (Supplement 1): 426.

https://doi.org/10.1182/blood.V130.Suppl_1.426.426

Published: 2017

Journal Articles

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 708.

https://doi.org/10.1182/blood.V128.22.708.708

Published: 2016

Journal Articles

Microenvironmental Links Between TET2/DNMT3A Mutations and Arginase 1 Overexpression in Human MDS/CMML

Alyssa Cull, MSc, Brooke Snetsinger, MSc, David Good, MD, Rena Buckstein, MD, Richard A. Wells, MD DPhil, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 3164.

https://doi.org/10.1182/blood.V128.22.3164.3164

Published: 2016

Journal Articles

TNF-Alpha Promotes Clonal Expansion of Tet2 Deficient Bone Marrow Progenitors in MDS

Samuel Ojo Abegunde, MD MSc., Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 731.

https://doi.org/10.1182/blood.V128.22.731.731

Published: 2016

Journal Articles

Differential Expression of TCF3 Target Genes Defines Subclasses of Diffuse Large B-Cell Lymphoma with Striking Differences in Clinical Outcome Following R-CHOP Therapy

Kathrin Tyryshkin, PhD, Yi D Li, MD, David Good, MD, Lois E. Shepherd, MD, Tara Baetz, MD FRCPC, Michael J. Rauh, MD PhD, David P. LeBrun, MD

Blood (2016) 128 (22): 3037.

https://doi.org/10.1182/blood.V128.22.3037.3037

Published: 2016

Journal Articles

Tet2 -Deficient Bone Marrow Progenitors Have a Proliferative Advantage in the Presence of TNF-Alpha and IFN-Gamma: Implications for Clonal Dominance in Inflammaging and MDS

Samuel Ojo Abegunde, MD BSc, MBBS, Michael J. Rauh, MD PhD

Blood (2015) 126 (23): 2850.

https://doi.org/10.1182/blood.V126.23.2850.2850

Published: 2015

Journal Articles

Tet2 Is a Novel Regulator of Murine Macrophage Differentiation and Polarization

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Michael J. Rauh, MD PhD

Blood (2015) 126 (23): 646.

https://doi.org/10.1182/blood.V126.23.646.646

Published: 2015

NARROW

Chronic TNF in the Aging Microenvironment Exacerbates TET2- loss-of-Function Myeloid Expansion

The Impact of Clonal Hematopoiesis on Clinical Outcomes and Clonal Dynamics in Older Lymphoma Patients Receiving Chemotherapy

Transcriptomic Analysis of Clonal Hematopoiesis in Solid Tumors Reveals Driver Mutation-Specific Patterns of Immune Dysregulation

A practical approach to curate clonal hematopoiesis of indeterminate potential in human genetic data sets

Breaking the CH inflammation-expansion cycle

DNA Methylation Profiles Capture Clinical and Molecular Heterogeneity of MDS and Can be Harnessed for the Development of Robust Biomarkers Predictive of Response to Azacitidine

CCUS and Low-Risk MDS Are Inherently Similar, Sharing Clonal and Clinical Features

Dynamic Stromal Changes in Myelofibrosis Patients Pre/Post JAK Inhibition Is Revealed in Clinically Archived Bone Marrow Biopsies By Smooth Muscle Actin (SMA)-CD34 Dual Immunohistochemistry

Impact of Tet2 Deficiency, and of TET2 Mutations in Clonal Hematopoiesis, on Neutrophil/Granulocyte Immune Function

Clinical Utility of Hematopathologist-Triaged NGS Testing When Investigating Patients with Suspected MDS

RNA-Seq Analysis of Clonal Hematopoiesis (CHIP) Blood Leukocytes Shows Dysregulation of Neutrophil / Innate Immunity-Related Genes

Validation and Clinical Impact of the Oncomine Myeloid Targeted DNA and RNA Ion Semiconductor Sequencing Assay

Somatic Mutations Associated with Myeloid Transformation of RUNX1 -Mutated Familial Platelet Disorders with Propensity to Myeloid Malignancies Using Targeted Next-Generation Sequencing

Feeding the Fire: The Comorbid and Inflammatory Backdrop of Clonal Hematopoiesis of Indeterminate Potential (CHIP) By Mutation Subtype

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Microenvironmental Links Between TET2/DNMT3A Mutations and Arginase 1 Overexpression in Human MDS/CMML

TNF-Alpha Promotes Clonal Expansion of Tet2 Deficient Bone Marrow Progenitors in MDS

Differential Expression of TCF3 Target Genes Defines Subclasses of Diffuse Large B-Cell Lymphoma with Striking Differences in Clinical Outcome Following R-CHOP Therapy

Tet2 -Deficient Bone Marrow Progenitors Have a Proliferative Advantage in the Presence of TNF-Alpha and IFN-Gamma: Implications for Clonal Dominance in Inflammaging and MDS

Tet2 Is a Novel Regulator of Murine Macrophage Differentiation and Polarization

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American Society of Hematology

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ASH Publications

American Society of Hematology

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