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Peter J. Valk
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Journal Articles

PU.1 Is Essential For MLL Leukemia Via Activation Of The Meis/HOX Pathway and A Monocytic Cytokine Mediated Anti-Apoptotic Inflammatory Program

Jing Zhou, Jun Wu, Bo Li, Dan Liu, Jian Yu, Xiaomei Yan, Si Zheng, Jiguang Wang, Lixia Zhang, Lin Zhang, Fuhong He, Qiang Li, Aili Chen, Yue Zhang, MD,, Xinghui Zhao, Yinghui Guan, Xiaohong Zhao, Jin Yan, Jun Ni, Marcelo Nobrega, Bob Löwenberg, MD, PhD, Ruud Delwel, Peter J. Valk, PhD, Ashish Kumar, MBBS, PhD, Xie Lu, Daniel G. Tenen, MD, Gang Huang, PhD, Qian-fei Wang, Ph.D
Journal: Blood
Blood (2013) 122 (21): 1276.
https://doi.org/10.1182/blood.V122.21.1276.1276
Published: 2013
Journal Articles

Microrna-551b Is Preferentially Expressed In Hematopoietic Stem and Multipotent Progenitor Cells and High Expression In Acute Myeloid Leukemia Is An Independent Prognostic Factor For Relapse and Poor Survival

David C. de Leeuw, MD, Fedor Denkers, Peter J. Valk, PhD, Gerrit Jan Schuurhuis, PhD, Gert J. Ossenkoppele, MD PhD, Linda Smit, PhD
Journal: Blood
Blood (2013) 122 (21): 1322.
https://doi.org/10.1182/blood.V122.21.1322.1322
Published: 2013
Journal Articles

Characterization of CEBPA Mutations and Promoter Hypermethylation in Pediatric Acute Myeloid Leukemia.

Iris H.I.M. Hollink, MD, Marry M. van den Heuvel-Eibrink, MD, PhD, Susan T.C.J.M. Arentsen-Peters, Martin Zimmermann, PhD, Justine K. Peeters, PhD, Peter J. Valk, PhD, Brian V. Balgobind, MD, Gertjan J.L. Kaspers, MD, PhD, Evelina S.J.M. de Bont, MD, PhD, Siebold S.N. de Graaf, MD, PhD, Jan Trka, PhD, Jan Stary, MD, PhD, Jean-Michel Cayuela, PhD, Andre Baruchel, MD, PhD, Ursula Creutzig, MD, PhD, Dirk Reinhardt, MD, PhD, Rob Pieters, MD, PhD, C. Michel Zwaan, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1605.
https://doi.org/10.1182/blood.V114.22.1605.1605
Published: 2009
Journal Articles

MicroRNAs in Normal Human Terminal Granulocytic Differentiation.

Su Ming Sun, Menno K Dijkstra, André C Bijkerk, Rik Brooijmans, PhD, Peter J Valk, PhD, Stefan J Erkeland, PhD, Bob Löwenberg, MD, PhD, Mojca Jongen-Lavrencic, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1463.
https://doi.org/10.1182/blood.V114.22.1463.1463
Published: 2009
Journal Articles

Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal

Michael Heuser, Laura M. Sly, Bob Argiropoulos, Florian Kuchenbauer, Courteney Lai, Andrew Weng, Malina Leung, Grace Lin, Christy Brookes, Stephen Fung, Peter J. Valk, Ruud Delwel, Bob Löwenberg, Gerald Krystal, R. Keith Humphries
Journal: Blood
Blood (2009) 114 (19): 3983–3993.
https://doi.org/10.1182/blood-2009-06-227603
Published: 2009
Includes: Supplemental data
Journal Articles

Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C

Maike Schwieger, Andrea Schüler, Martin Forster, Afra Engelmann, Michael A. Arnold, Ruud Delwel, Peter J. Valk, Jürgen Löhler, Robert K. Slany, Eric N. Olson, Carol Stocking
Journal: Blood
Blood (2009) 114 (12): 2476–2488.
https://doi.org/10.1182/blood-2008-05-158196
Published: 2009
Journal Articles

A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene

Bin Yin, Ruud Delwel, Peter J. Valk, Margaret R. Wallace, Mignon L. Loh, Kevin M. Shannon, David A. Largaespada
Journal: Blood
Blood (2009) 113 (5): 1075–1085.
https://doi.org/10.1182/blood-2008-03-144436
Published: 2009
Includes: Supplemental data
Journal Articles

Bcl11a Causes p21 Cip1 Down-Regulation and Transplantable Leukemia in Nf1 -Deficient Mice.

Bin Yin, PhD, Ruud Delwel, PhD, Peter J. Valk, PhD, Mignon L. Loh, MD, Kevin M. Shannon, MD, David A. Largaespada, PhD
Journal: Blood
Blood (2007) 110 (11): 2657.
https://doi.org/10.1182/blood.V110.11.2657.2657
Published: 2007
Journal Articles

Unique Gene Expression Profiles of AML Patients with CEBPA Mutations.

Bas J. Wouters, MD, Claudia A. Erpelinck, Peter J. Valk, PhD, Roel G. Verhaak, M.Sc, Bob Löwenberg, MD, PhD, Ruud Delwel, PhD
Journal: Blood
Blood (2005) 106 (11): 745.
https://doi.org/10.1182/blood.V106.11.745.745
Published: 2005
Journal Articles

New Insights in Mechanims Involved in Apoptosis Resistance in Acute Myeloid Leukemia.

Corine J. Hess, Johannes Berkhof, PhD, Fedor Denkers, Gert J. Ossenkoppele, PhD, Peter J. Valk, PhD, Ruud Delwel, PhD, Quinten Waisfisz, PhD, Gerrit Jan Schuurhuis, PhD
Journal: Blood
Blood (2005) 106 (11): 1215.
https://doi.org/10.1182/blood.V106.11.1215.1215
Published: 2005
Journal Articles

Pathogenetic Significance of Retrovirus-Tagged Mouse Myeloid Leukemia Genes for Human AML.

Stefan J. Erkeland, Roel G.W. Verhaak, Marijke Valkhof, Ruud Delwel, Peter J. Valk, Bob Lowenberg, Ivo P. Touw
Journal: Blood
Blood (2004) 104 (11): 468.
https://doi.org/10.1182/blood.V104.11.468.468
Published: 2004