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Journal Articles

Clinical Significance and Biomarkers to Predict Unsustained Complete Remission in Transplant-Eligible Multiple Myeloma

Ana Jimenez-Ubieto, Bruno Paiva, PhD, Joaquin Martinez Lopez, María Teresa Cedena, MD, Noemi Puig, MD PhD, Albert Oriol, MD, Maria Jesús Blanchard, MD, Rafael Rios, MD PhD, Lucia Lopez-Anglada, PhD, Jesús Martín, Rafael Martínez, Anna Sureda Balari, MD PhD, Miguel Hernández, Javier de la Rubia, Isabel Krsnik, MD PhD, Valentin Cabañas, MD, Luis Palomera, MD PhD, Joan Bargay, MD, Jose Maria Moraleda, MD PhD, Laura Rosiñol, María-Victoria Mateos, MD PhD, Jesus F. San-Miguel, MD PhD, Joan Bladé, MD PhD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-136181
Published: 2020
Journal Articles

Clinical Validation of a NGS Capture Panel to Identify Mutations, Copy Number Variations and Translocations in Patients with Multiple Myeloma

Isabel Cuenca, MSc, Alejandro Medina, MD, Laura Rosinol, MD PhD, Iria Vazquez, PhD BSc, Ricardo Sanchez, Norma C. Gutierrez, MD PhD, Yanira Ruiz-Heredia, Santiago Barrio, Albert Oriol, MD, Maria Luisa Martin-Ramos, Manuela Fernández-Guijarro, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda Balari, MD PhD, Miguel T Hernández, Javier de la Rubia, Gorka Alkorta, Xabier Agirre, PhD, Gonzalo R Ordóñez, Rafael Valdés-Mas, Maria-Victoria Mateos, MD PhD, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD, Maria Jose Calasanz, PhD BSc, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-140711
Published: 2020
Journal Articles

Making Clinical Decisions to Change Therapy Using Measurable Residual Disease Improves the Outcome in Multiple Myeloma

Joaquin Martinez Lopez, Rafael Alonso Fernández, Sandy W. Wong, MD, Rafael Rios, MD PhD, Nina Shah, MD, Maria Teresa Cedena Romero, MD PhD, Yanira Ruiz-Heredia, Jose M. Sanchez, MD, Santiago Barrio Garcia, PhD, Thomas Martin, III, MD, Jeffrey L. Wolf, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-140352
Published: 2020
Journal Articles

Randomized Phase 2 Study of Weekly Carfilzomib 70 Mg/m2 and Dexamethasone Plus/Minus Cyclophosphamide in Relapsed and/or Refractory Multiple Myeloma (RRMM) Patients (GEM-KyCyDex)

Maria-Victoria Mateos, MD PhD, Enrique M. Ocio, MDPhD, Anna Sureda Balari, MD PhD, Albert Oriol, Esther González Garcia, MD, Maria José Moreno, Miquel Granell, MD, Fernando Escalante, MD, Veronica Gonzalez De La Calle, MD PhD, Laura Rosinol Dachs, Estrella Carrillo-Cruz, MD, Joaquín Martínez-López, Maria Victoria Dourdil Sahun, Marta Sonia Gonzalez, MD, Jaime Perez De Oteyza, MDPhD, Felipe De Arriba, PhD, Miguel T Hernández, MD PhD, Aránzazu García Mateo, PhD, Ana Pilar Gonzalez, PhD, Rafael Rios, MD PhD, Carmen Cabrera, Juan Jose Bargay, Paula Rodriguez-Otero, MD, Felipe Casado, Maria Casanova, MD, María Jesús Blanchard, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-140934
Published: 2020
Journal Articles

Circulating Tumor Cells (CTCs) for Comprehensive and Multiregional Non-Invasive Genetic Characterization of Multiple Myeloma (MM)

Juan José Garcés, Gabriel Bretones, Leire Burgos, Rafael Valdes-Mas, Diego Alignani, PhD, Diana Álvarez Puente, Ibai Goicoechea, PhD, Miguel García Álvarez, Sonia Garate, Idoia Rodriguez, Maria Jose Calasanz, PhD BSc, Paula Rodriguez, MD, Rafael Rios, MD PhD, Joaquin Martinez-Lopez, MD PhD, Pamela Millacoy, Luis Palomera, MD PhD, Rafael Del Orbe, MD PhD, Albert Pérez, MD, Xabier Agirre, PhD, Juan Flores-Montero, Luzalba Sanoja-Flores, Alberto Orfao, MD PhD, Halima El Omri, Felipe Prosper, MD PhD, Carlos Lopez-Otin, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3064.
https://doi.org/10.1182/blood-2019-126527
Published: 2019
Journal Articles

Single-Cell Characterization of the Multiple Myeloma (MM) Immune Microenvironment Identifies CD27-Negative T Cells As Potential Source of Tumor-Reactive Lymphocytes

Cirino Botta, MD, Cristina Pérez Ruiz, Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Aintzane Zabaleta, PhD, Leire Burgos, Catarina Maia, Sara Rodríguez, PhD, Idoia Rodriguez, Sarai Sarvide, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Erika Lorenzo-Vivas, PhD, Laura Rosinol Dachs, Albert Oriol, MD, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda, MD PhD, Rafael Martínez, Jesús Martín, Joan Bargay, MD PhD, Javier De La Rubia, Marco Rossi, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Massimo Gentile, Juana Merino, Felipe Prosper, MD PhD, Alberto Orfao, MD PhD, Maria-Victoria Mateos, Juan-José Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 506.
https://doi.org/10.1182/blood-2019-123974
Published: 2019
Journal Articles

Qip-Mass Spectrometry in High Risk Smoldering Multiple Myeloma Patients Included in the GEM-CESAR Trial: Comparison with Conventional and Minimal Residual Disease IMWG Response Assessment

Noemi Puig, MD PhD, Maria-Victoria Mateos, Teresa Contreras, Bruno Paiva, PhD, María Teresa Cedena, José J Pérez, Irene Aires, Cristina Agullo, Joaquin Martinez-Lopez, MD PhD, Paula Rodriguez Otero, Veronica Gonzalez De La Calle, MD PhD, Marta Sonia Gonzalez, MD, Albert Oriol, Norma C. Gutierrez, MD PhD, Rafael Rios, MD PhD, Laura Rosiñol, Miguel Angel Alvarez, MD, Maria Jose Calasanz, PhD BSc, Joan Bargay, MD PhD, Ana Pilar Gonzalez, PhD, Adrián Alegre, MD, Fernando Escalante, MD, Rafael Martínez, Javier de la Rubia, MD PhD, Ana Isabel Teruel, MDcal Doctor, Felipe De Arriba, PhD, Luis Palomera, MD PhD, Miguel-Teodoro Hernández, Javier López, MD, Jesús Martín, Aránzazu García Mateo, PhD, Ramón García-Sanz, MD PhD, Enrique M. Ocio, Joan Bladé, MD PhD, Juan-José Lahuerta, MD PhD, Jesus F. San-Miguel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 581.
https://doi.org/10.1182/blood-2019-127717
Published: 2019
Journal Articles

Heavy and Light Chain Monitoring in High Risk Smoldering Multiple Myeloma Patients Included in the GEM-CESAR Trial: Comparison with Conventional and Minimal Residual Disease IMWG Response Assessment

Noemi Puig, MD PhD, Teresa Contreras, Bruno Paiva, PhD, María Teresa Cedena, José J Pérez, Irene Aires, Cristina Agullo, Joaquin Martinez-Lopez, MD PhD, Paula Rodriguez Otero, Veronica Gonzalez De La Calle, MD PhD, Marta Sonia Gonzalez, MD, Albert Oriol, Norma C. Gutierrez, MD PhD, Rafael Rios, MD PhD, Laura Rosiñol, Miguel Angel Alvarez, MD, Maria Jose Calasanz, PhD BSc, Joan Bargay, MD PhD, Ana Pilar Gonzalez, PhD, Adrián Alegre, MD, Fernando Escalante, MD, Rafael Martínez, Javier de la Rubia, MD PhD, Ana Isabel Teruel, MDcal Doctor, Felipe De Arriba, PhD, Luis Palomera, MD PhD, Miguel-Teodoro Hernández, Javier López, MD, Jesús Martín, Aránzazu García Mateo, PhD, Enrique M. Ocio, Ramón García-Sanz, MD PhD, Joan Bladé, MD PhD, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD, Maria-Victoria Mateos
Journal: Blood
Blood (2019) 134 (Supplement_1): 1852.
https://doi.org/10.1182/blood-2019-128655
Published: 2019
Journal Articles

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination

Juan José Garcés, Michal Šimíček, Marco Vicari, Lucie Brozova, MSc, Leire Burgos, Renata Bezděková, MSc., Diego Alignani, PhD, Maria Jose Calasanz, BSc, PhD, Katerina Growkova, Ludek Pour, MD, Rafael Rios, MD PhD, Joaquin Martinez-Lopez, MD PhD, Pamela Millacoy, Luis Palomera, MD PhD, Rafael Del Orbe, Sonia Garate, Laura Blanco, Patricia Maiso, PhD, Zuzana Chyra, Alexander Vdovin, Tomas Jelinek, Cirino Botta, MD, Halima El Omri, Xabier Agirre, PhD, Felipe Prosper, MD PhD, Roman Hajek, MD PhD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 245.
https://doi.org/10.1182/blood-2018-99-113331
Published: 2018
Journal Articles

Curativestategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Followed By HDT-ASCT, Consolidation with Krd and Maintenance with Rd

Maria-Victoria Mateos, MD PhD, Joaquin Martínez-López, MD PhD, Paula Rodriguez Otero, MD, Enrique M. Ocio, MD, Marta Sonia Gonzalez, MD, Albert Oriol, MD, Norma C. Gutierrez, MD PhD, Bruno Paiva, MD PhD, Rafael Rios, MD PhD, Laura Rosinol, MD PhD, Miguel Angel Alvarez, MD, Maria Jose Calasanz, BSc, PhD, Joan Bargay, MD PhD, Ana Pilar Gonzalez, PhD, Adrián Alegre, MD, Fernando Escalante, MD, Rafael Martínez, Noemi Puig, MD PhD, Javier De La Rubia, MD, Ana Isabel Teruel, MDcal Doctor, María Teresa Cedena, Felipe De Arriba, PhD, Luis Palomera, MD PhD, Miguel T Hernández, MD PhD, Javier Lopez Jimenez, MD PhD, Jesús Martín, Esther Piensa, Aránzazu García Mateo, PhD, Veronica Gonzalez De La Calle, MD PhD, Joan Bladé, MD PhD, Juan Jose Lahuerta, MD PhD, Jesus F San-Miguel, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2142.
https://doi.org/10.1182/blood-2018-99-112656
Published: 2018
Journal Articles

Detailed Phenotypic, Molecular and Functional Profiling of Myeloid Derived Suppressor Cells (MDSCs) in the Tumor Immune Microenvironment (TIME) of Multiple Myeloma (MM)

Cristina Pérez Ruiz, Aintzane Zabaleta, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Juana Merino, Diego Alignani, PhD, Sonia Garate, Ibai Goicoechea, PhD, David Lara-Astiaso, PhD, Sarai Sarvide, Cirino Botta, MD, Joaquin Martinez Lopez, MD PhD, Albert Oriol, MD, Rafael Rios, MD PhD, Laura Rosinol, MD PhD, Maria-Victoria Mateos, MD PhD, Juan-José Lahuerta, MD PhD, Joan Bladé, MD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4436.
https://doi.org/10.1182/blood-2018-99-111102
Published: 2018
Journal Articles

Integrated Analysis of Randomized Controlled Trials Evaluating Bortezomib + Lenalidomide + Dexamethasone or Bortezomib + Thalidomide + Dexamethasone Induction in Transplant-Eligible Newly Diagnosed Multiple Myeloma

Laura Rosinol Dachs, Benjamin Hebraud, Albert Oriol, MD, Anne-Laurène Colin, Rafael Rios, MD PhD, Cyrille Hulin, Maria Jesús Blanchard, MD, Denis Caillot, Anna Sureda, MD, Miguel T Hernández, MD PhD, Bertrand Arnulf, Maria-Victoria Mateos, MD PhD, Margaret Macro, Jesús F San-Miguel, MD, Karim Belhadj, Juan Jose Lahuerta, MD PhD, Guang Chen, M. Brigid Garelik, Joan Bladé, MD, Philippe Moreau, Michel Attal, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3245.
https://doi.org/10.1182/blood-2018-99-112659
Published: 2018
Journal Articles

Double Vs Single Autologous Stem Cell Transplantation for Newly Diagnosed Multiple Myeloma: Long-Term Follow-up (10-Years) Analysis of Randomized Phase 3 Studies

Michele Cavo, MD, Hartmut Goldschmidt, MD, Laura Rosinol, MD PhD, Lucia Pantani, MD, Sonja Zweegman, MDPhD, Hans Jürgen Salwender, MD, Juan Jose Lahuerta, MD PhD, Henk M. Lokhorst, MD PhD, Maria Teresa Petrucci, MD, Igor Blau, MD PhD, Albert Oriol, MD, Nicoletta Testoni, BSc, Katja Weisel, MD, Rafael Rios, MD PhD, Francesca Patriarca, MD, Jesús Blanchard, MD, Luca Dozza, MSc, Maria-Victoria Mateos, MD PhD, Monica Galli, MD, Jesus F San-Miguel, MD PhD, Mario Boccadoro, MD, Joan Blade, MD, Pieter Sonneveld, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 124.
https://doi.org/10.1182/blood-2018-99-112899
Published: 2018
Journal Articles

Clinical Significance and Transcriptional Profiling of Persistent Minimal Residual Disease (MRD) in Multiple Myeloma (MM) Patients with Standard-Risk (SR) and High-Risk (HR) Cytogenetics

Ibai Goicoechea, PhD, Noemi Puig, MD PhD, María Teresa Cedena, Lourdes Cordon, Maria-Belen Vidriales, MD, Leire Burgos, Juan Flores-Montero, Norma C. Gutierrez, MD PhD, Maria Jose Calasanz, BSc, PhD, Maria Luisa Martin-Ramos, David Lara-Astiaso, PhD, Amaia Vilas-Zornoza, PhD, Diego Alignani, PhD, Idoia Rodriguez, Sarai Sarvide, Ramon Garcia-Sanz, MD PhD, Joaquin Martinez-Lopez, MD PhD, Albert Oriol, MD, Rafael Rios, MD PhD, Jesús Martín, Rafael Martínez, Josep Sarra, Miguel T Hernández, MD PhD, Javier De La Rubia, MD, Isabel Krsnik, Jose Maria Moraleda, Luis Palomera, MD PhD, Joan Bargay, MD PhD, Alberto Orfao, MD PhD, Laura Rosiñol, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, MD PhD, Joan Bladé, MD PhD, Jesus F San-Miguel, MD PhD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 112.
https://doi.org/10.1182/blood-2018-99-113312
Published: 2018
Journal Articles

Immunofixation (IF) in Urine Is Really Necessary to Define Complete Remission in Multiple Myeloma (MM)? a Subanalysis from the Pethema/GEM2012MENOS65 Phase III Clinical Trial

Ana Jiménez Ubieto, MD PhD, Bruno Paiva, MD PhD, Joaquin Martínez-López, MD PhD, Laura Rosinol, MD PhD, Maria Teresa Cedena Romero, MD PhD, Maria Jose Calasanz, BSc, PhD, Noemi Puig, MD PhD, Ramon Garcia-Sanz, MD PhD, Norma C. Gutierrez, MD PhD, Maria Luisa Martin-Ramos, Albert Oriol, MD, José Gonzalez Medina, Rafael Alonso Fernandez, Jesús Blanchard, MD, Rafael Rios, MD PhD, Jesús Martín, Rafael Martinez Martinez, Josep Sarra, Miguel-Teodoro Hernández, Javier De La Rubia, MD, Isabel Krsnik, MD PhD, Jose Maria Moraleda, Luis Palomera, MD PhD, Maria-Victoria Mateos, MD PhD, Jesús F San-Miguel, MD, Joan Bladé, MD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 474.
https://doi.org/10.1182/blood-2018-99-115050
Published: 2018
Journal Articles

Retrospective Observational Study from the Experience in Our Center of the Employment of Daratumumab in Multiple Myeloma

Estefanía Morente Constantin, Pablo Romero Garcia, Maria Almudena Garcia-Ruiz, Rafael Rios, MD PhD, Esther Clavero Sanchez, Manuel Jurado, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5630.
https://doi.org/10.1182/blood-2018-99-114740
Published: 2018
Journal Articles

Absence of Contribution to a Differential Outcome of the Stringent Complete Response IMWG Category Respect to the Conventional CR in Multiple Myeloma. a Validation Analysis Based on the Pethema/GEM2012MENOS65 Phase III Clinical Trial

Ana Jiménez Ubieto, MDPhD, Joaquin Martinez Lopez, MD PhD, Laura Rosinol, MD PhD, Bruno Paiva, MD PhD, María Teresa Cedena, Noemi Puig, MD PhD, Maria Jose Calasanz, BSc, PhD, José Gonzalez Medina, Maria Luisa Martin-Ramos, Rafael Alonso Fernandez, Albert Oriol, MD, Jesús Blanchard, MD, Enrique M. Ocio, MD, Javier De La Rubia, MD, Rafael Rios, MD PhD, Jesús Martín, Miguel-Teodoro Hernández, Isabel Krsnik, MD PhD, Jose Maria Moraleda, Luis Palomera, MD PhD, Joan Bargay, MD PhD, Maria-Victoria Mateos, MD PhD, Jesús F San-Miguel, MD, Joan Bladé, MD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1943.
https://doi.org/10.1182/blood-2018-99-116604
Published: 2018
Journal Articles

Type 2 Diabetes-Related Variants Influence on the Risk of Developing Multiple Myeloma: Results from the Immense Consortium

Juan Sainz, PhD, Carmen Belén Lupiañez, Daniele Campa, PhD, Gabriele Buda, MD, Hernan Jose Moreno, MD, Marek Dudziński, PhD, Charles Dumontet, MD PhD, Ramón García-Sanz, MD PhD, Krzysztof Jamroziak, MD PhD, Artur J. Jurczyszyn, MD PhD, Stefano Landi, MD PhD, Fabienne Lesueur, PhD, Herlander Marques, MD PhD, Joaquín Martínez-López, MD PhD, Victor Moreno, MD PhD, Mario Petrini, MD PhD, Rui Manuel Reis, MD PhD, Zofia Szemraj-Rogucka, MD PhD, Annette Juul Vangsted, MD PhD, Judit Varkonyi, MD PhD, Ulla Vogel, MD PhD, Marzena Wątek, MD PhD, Federico Canzian, PhD, Rafael Rios, MD
Journal: Blood
Blood (2014) 124 (21): 2044.
https://doi.org/10.1182/blood.V124.21.2044.2044
Published: 2014