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Richard Rosenquist, MD, PhD
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Journal Articles

BTK Leu528Trp - a Potential Secondary Resistance Mechanism Specific for Patients with Chronic Lymphocytic Leukemia Treated with the Next Generation BTK Inhibitor Zanubrutinib

Sasanka M. Handunnetti, MBBS, FRACP, FRCPA, Chloe Pek Sang Tang, MBBS, FRACP, Tamia Nguyen, Xing Zhou, Ella Thompson, PhD BSc, Hanzi Sun, Haimei Xing, Bo Zhang, Yin Guo, Lesley Ann Sutton, PhDBSc, Paolo Ghia, MD PhD, Richard Rosenquist, MD PhD, Lydia Scarfo, MD, Silvia Bonfiglio, John F. Seymour, MBBS, PhD FRACP, Mary Ann Anderson, MBBS, PhD FRACP, FRCPA, Andrew W. Roberts, MBBS, PhD, David C.S. Huang, MBBS MRCP PhD, Ye Liu, Chan Y. Cheah, David Alan Westerman, MBBS, FRCPA, FRACP, Paul Sung-Hao Yeh, MBBS, FRCPA, FRACP, Constantine S. Tam, MBBS, MD, Piers Blombery, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 170.
https://doi.org/10.1182/blood-2019-125488
Published: 2019
Journal Articles

Higher Order Restrictions of the Immunoglobulin Repertoire in CLL: The Illustrative Case of Stereotyped Subsets #2 and #169

Katerina Gemenetzi, Andreas Agathangelidis, PhD, Fotis Psomopoulos, Karla Plevova, PhD, Lesley-Ann Sutton, Kostas Pasentsis, Achilles Anagnostopoulos, Raphael Sandaltzopoulos, Richard Rosenquist, MD PhD, Frederic Davi, MD PhD, Sarka Pospisilova, Prof PhD, Kostas Stamatopoulos, Anastasia Chatzidimitriou
Journal: Blood
Blood (2019) 134 (Supplement_1): 5453.
https://doi.org/10.1182/blood-2019-128017
Published: 2019
Journal Articles

Diffuse Large B-Cell Lymphoma Remodels the Fibroblastic Reticular Network That Acquires Aberrant Immunosuppressive Capabilities; Implications for the Regulation of Anti-Tumor Immunity in the Immuno-Oncology Era

Benedetta Apollonio, PhD, Peter Jarvis, MSc, Beth Phillips, MBBS, FRCPath, BSc, Andrea Kuhnl, Jon Salisbury, Georgios Zacharioudakis, Lesley-Ann Sutton, Richard Rosenquist, MD PhD, Ruth Jarrett, MBBChir, FRCPath, FRCP, Rose-Marie Amini, Anna Vardi, MD PhD, Alan G. Ramsay, BSc,MSc,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 675.
https://doi.org/10.1182/blood-2018-99-116409
Published: 2018
Journal Articles

A Prognostic Tool for the Identification of Patients with Early Stage Chronic Lymphocytic Leukemia at Risk of Progression

Adalgisa Condoluci, MD, Lodovico Terzi di Bergamo, Lorenzo De Paoli, MD, Julio Delgado, MD, Massimo Gentile, MD, Michael Doubek, MD PhD, Francesca Romana Mauro, Mattias Mattsson, MD, Giovanna Cutrona, PhD, Jana Kotaskova, Clara Deambrogi, PhD, Bernhard Gerber, Valeria Spina, PhD, Alessio Bruscaggin, PhD, Emanuele Zucca, Franco Cavalli, MD, Georg Stuessi, MD, Antonino Neri, MD, Manlio Ferrarini, MD, Richard Rosenquist, MD PhD, Robin Foà, MD, Sarka Pospisilova, Fortunato Morabito, MD, Emili Montserrat, MD, Gianluca Gaidano, MD PhD, William G. Wierda, MD PhD, Davide Rossi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1834.
https://doi.org/10.1182/blood-2018-99-116325
Published: 2018
Journal Articles

Remarkable Functional Constraints on the Antigen Receptors of CLL Stereotyped Subset #2: High-Throughput Immunogenetic Evidence

Katerina Gemenetzi, Andreas Agathangelidis, PhD, Lesley-Ann Sutton, Elisavet Vlachonikola, Chrysi Galigalidou, Fotis Psomopoulos, Maria Gounari, Achilles Anagnostopoulos, Raphael Sandaltzopoulos, Richard Rosenquist, MD PhD, Kostas Stamatopoulos, MD PhD, Anastasia Hadzidimitriou, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1839.
https://doi.org/10.1182/blood-2018-99-119125
Published: 2018
Journal Articles

RPS15 mutations Repress mRNA Translation in Chronic Lymphocytic Leukemia Cells

Stavroula Ntoufa, Stamatia Laidou, Fotis Psomopoulos, Marina Gerousi, Larry Mansouri, Georgios Tsiolas, Nikos Papakonstantinou, Achilles Anagnostopoulos, Niki Stavroyianni, Antonios M. Makris, Anastasia Hadzidimitriou, PhD, Richard Rosenquist, MD PhD, Kostas Stamatopoulos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1843.
https://doi.org/10.1182/blood-2018-99-118150
Published: 2018
Journal Articles

IGHV Gene Replacement: A Potential Mechanism for Establishing Stereotypy in Certain Cases of Chronic Lymphocytic Leukemia

Sophia Yancopoulos, PhD, Wentian Li, PhD, Xiao J. Yan, MD PhD, Andreas Agathangelidis, PhD, Anastasia Hadzidimitriou, PhD, Frederic Davi, MD PhD, Richard Rosenquist, MD PhD, Paolo Ghia, MD PhD, Kostas Stamatopoulos, MD PhD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1841.
https://doi.org/10.1182/blood-2018-99-119803
Published: 2018
Journal Articles

SHP1 Deficiency Is Responsible for the Constitutive Activation of the BCR Pathway in GCB DLBCL

Binu K Sasi, PhD, Sven Turkalj, BS, Hilal Kalkan, BS, Fabiola Porro, MS, Engin Bojnik, PhD, Beata Pyrzynska, PhD, Abdessamad Zerrouqi, PhD, Malgorzata Bobrowicz, PhD, Magdalena Winiarska, PhD, Valdemar Priebe, MS, Francesco Bertoni, MD, Larry Mansouri, PhD, Richard Rosenquist, MD PhD, Dimitar G Efremov, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2860.
https://doi.org/10.1182/blood-2018-99-118120
Published: 2018
Journal Articles

Genomic Complexity in Chronic Lymphocytic Leukemia Defined By Array-Based Analysis: Definitions, Associations with Other Biomarkers and Clinical Impact

Alexander Leeksma, MD, Panagiotis Baliakas, MD PhD, Clemens Mellink, PhD, Theodoros Moysiadis, PhD BSc, MSc, Anna Puiggros, PhD, Karla Plevova, PhD, Eva van den Berg, PhD, Eric Eldering, Aron Skaftason, Larry Mansouri, Rebeqa Gunnarsson, PhD, Paolo Ghia, MD PhD, Blanca Espinet, PhD, Sarka Pospisilova, MD PhD, Florence Nguyen-Khac, MD PhD, David Oscier, MD PhD, Kostas Stamatopoulos, Claudia Haferlach, MD, Richard Rosenquist, MD PhD, Jonathan C Strefford, PhD, Marian Stevens-Kroef, PhD, Arnon P. Kater, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4280.
https://doi.org/10.1182/blood.V130.Suppl_1.4280.4280
Published: 2017
Journal Articles

External Stimuli Modulate EZH2 Expression in Chronic Lymphocytic Leukemia. Rationale and Evidence for Synergistic Anti-Tumor Effects of B Cell Signaling and EZH2 Inhibitors

Elisavet Chartomatsidou, Stavroula Ntoufa, Konstantia Kotta, Marianna Akritidou, Theoni Trangas, Niki Stavroyianni, Achilles Anagnostopoulos, Richard Rosenquist, MD PhD, Paolo Ghia, Nikos Papakonstantinou, Kostas Stamatopoulos
Journal: Blood
Blood (2017) 130 (Supplement 1): 4295.
https://doi.org/10.1182/blood.V130.Suppl_1.4295.4295
Published: 2017
Journal Articles

Different Time-Dependent Risk for Disease Evolution in Chronic Lymphocytic Leukemia with Distinct IGHV Gene Somatic Hypermutation Status

Theodoros Moysiadis, PhD BSc, MSc, Panagiotis Baliakas, MD PhD, Davide Rossi, MD PhD, Mark Catherwood, Jonathan C Strefford, PhD, Julio Delgado, MD, Achilles Anagnostopoulos, Chrysoula Belessi, Niki Stavroyianni, Sarka Pospisilova, MD PhD, David Oscier, MD PhD, Gianluca Gaidano, MD PhD, Elias Campo, MD PhD, Richard Rosenquist, MD PhD, Paolo Ghia, Kostas Stamatopoulos
Journal: Blood
Blood (2017) 130 (Supplement 1): 3001.
https://doi.org/10.1182/blood.V130.Suppl_1.3001.3001
Published: 2017
Journal Articles

Clinical Importance of DNA Methylation Signatures in Chronic Lymphocytic Leukaemia Patients Treated with Chemo-Immunotherapy

Harindra Amarasinghe, PhD, Tomasz K Wojdacz, PhD MSc, Matthew John Jerome Rose-Zerilli, PhD, Alice Beattie, Jade Forster, PhD, Latha Kadalayil, Stuart Blakemore, PhD, Helen Parker, PhD, Marta Larrayoz, PhD, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J Steele, PhD, Richard Rosenquist, MD PhD, Andrew Collins, Andrew Pettitt, FRCPath, PhD, Peter Hillmen, MBChB, PhD, Pauline Robbe, MSc, Christopher Plass, Anna Schuh, MD PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Christopher C. Oakes, PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 56.
https://doi.org/10.1182/blood.V130.Suppl_1.56.56
Published: 2017
Journal Articles

Genome-Wide DNA Methylation Profiling of Chronic Lymphocytic Leukemia Subsets Carrying Stereotyped B Cell Receptors

Richard Rosenquist, MD PhD, Larry Mansouri, Sujata Bhoi, Giancarlo Castellano, PhD, Lesley Ann Sutton, PhDBSc, Nikos Papakonstantinou, Ana Queirós, MSc, Panagiotis Baliakas, MD PhD, Sara Ek, PhD, Venera Kuci Emruli, Karla Plevova, PhD, Stavroula Ntoufa, Zadie Davis, Emma Young, Hanna Goransson-Kultima, Anders Isaksson, Karin E Smedby, MD PhD, Gianluca Gaidano, MD PhD, Anton W Langerak, Frederic Davi, Davide Rossi, MD PhD, David Oscier, MD PhD, Sarka Pospisilova, MD PhD, Paolo Ghia, MD PhD, Elias Campo, MD PhD, Kostas Stamatopoulos, Inaki Martin Subero, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 57.
https://doi.org/10.1182/blood.V130.Suppl_1.57.57
Published: 2017
Journal Articles

Profiling the Genomic Landscape at the Early Stages of CLL: Low Genomic Complexity and Paucity of Driver Mutations in MBL and Indolent CLL

Andreas Agathangelidis, Viktor Ljungström, Lydia Scarfò, Claudia Fazi, Maria Gounari, Tatiana Pandzic, Lesley-Ann Sutton, Kostas Stamatopoulos, MD PhD, Giovanni Tonon, Richard Rosenquist, MD PhD, Paolo Ghia
Journal: Blood
Blood (2016) 128 (22): 3214.
https://doi.org/10.1182/blood.V128.22.3214.3214
Published: 2016
Journal Articles

How Many Ontogenetic Roads to Mantle-Cell Lymphoma? Immunogenetic and Immunohistochemical Evidence

Evi Pouliou, Aliki Xochelli, Evangelia Stalika, Lesley-Ann Sutton, Alba Navarro, Andreas Agathangelidis, Kypros Dimosthenous, George Kanellis, Achilles Anagnostopoulos, Efstratios Patsouris, Penelope Korkolopoulou, Christer Sundstrom, Paolo Ghia, Maurilio Ponzoni, Birgitta Sander, Elias Campo, MD, PhD, Richard Rosenquist, MD PhD, Anastasia Hadzidimitriou, Kostas Stamatopoulos, Theodora Papadaki
Journal: Blood
Blood (2014) 124 (21): 3005.
https://doi.org/10.1182/blood.V124.21.3005.3005
Published: 2014
Journal Articles

Deep-Sequencing Reveals the Molecular Landscape of Splenic Marginal Zone Lymphoma: Biological and Clinical Implications

Matthew JJ Rose-Zerilli, PhD, Marina Parry, Viktor Ljungstrom, Jane Gibson, Jun Wang, Renata Walewska, Helen Parker, PhD, Anton Parker, Zadie Davis, Anne Catherine Gardiner, Neil McIver-Brown, Christina H. Kalpadakis, MD, Aliki Xochelli, Achilles Anagnostopoulos, Claudia Fazi, PhD, David Gonzalez de Castro, PhD, Claire Dearden, MD, Guy Pratt, Richard Rosenquist, MD PhD, Margaret Ashton-Keys, Francesco Forconi, Andrew Collins, PhD, Paolo Ghia, MD PhD, Estella Matutes, MD PhD, Gerassimos A Pangalis, Kostas Stamatopoulos, David G Oscier, MD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2014) 124 (21): 76.
https://doi.org/10.1182/blood.V124.21.76.76
Published: 2014
Journal Articles

Genetic Determinants of Disease Phenotype and Clinical Outcome in Myelodysplastic Syndromes with Ring Sideroblasts

Luca Malcovati, MD, Mohsen Karimi, PhD, Elli Papaemmanuil, PhD, Ilaria Ambaglio, MD, Martin Jadersten, MDPhD, Monika Jansson, Chiara Elena, MD, Anna Gallì, PhD, Gunilla Walldin, MD, Matteo G Della Porta, MD, Klas Raaschou-Jensen, MD, Erica Travaglino, Klaus Kallenbach, MD PhD, Viktor Ljungstrom, Emanuela Boveri, MD, Rosangela Invernizzi, MD, Richard Rosenquist, MD PhD, Peter J. Campbell, PhD, Mario Cazzola, MD, Eva Hellstrom-Lindberg
Journal: Blood
Blood (2014) 124 (21): 825.
https://doi.org/10.1182/blood.V124.21.825.825
Published: 2014
Journal Articles

A Systematic Search Into The Role Of IGHV Gene Replacement In Shaping The Immunoglobulin Repertoire Of Chronic Lymphocytic Leukemia

Sophia Yancopoulos, PhD, Xiao-Jie Yan, MD PhD, Andreas Agathangelidis, Wentian Li, Ph.D., Chrysoula Belessi, Paolo Ghia, MD, PhD, Richard Rosenquist, MD, PhD, Frederic Davi, MD, PhD, David Graham Oscier, MD, Sarka Pospisilova, Panagiotis Panagiotidis, MD, Lin Huang, PhD, Zhixin Zhang, PhD, Steven L. Allen, MD, Jaqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Kostas Stamatopoulos, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2013) 122 (21): 4129.
https://doi.org/10.1182/blood.V122.21.4129.4129
Published: 2013
Journal Articles

Prognostic Assessment In Patients With Chronic Lymphocytic Leukemia (CLL) In Clinical Practice: A European Research Initiative On CLL (ERIC) Survey

Carol Moreno, MD, Stephan Stilgenbauer, MD, Marco Montillo, MD, Robak Tadeusz, MD, Eva Kimby, MD, Richard Rosenquist, MD, PhD, David Oscier, MD
Journal: Blood
Blood (2013) 122 (21): 4156.
https://doi.org/10.1182/blood.V122.21.4156.4156
Published: 2013
Journal Articles

Chronic Lymphocytic Leukemia Patients with IGHV Genes Carrying Only Silent Mutations Have A Longer Time From Diagnosis to Initial Therapy Than Patients Expressing B-Cell Receptors with No Somatic Mutations

Matthew Kaufman, MD, Xiao J. Yan, MD, PhD, Emanuela M. Ghia, PhD, Donna Neuberg, ScD, Laura Z. Rassenti, Ph.D., Kostas Stamatopoulos, MD, Paolo Ghia, MD, PhD, David G Oscier, MD, Frederic Davi, MD, PhD, Richard Rosenquist, MD, PhD, Chrysoula Belessi, MD, Zadie Davis, PhD, Andreas Agathangelidis, Neil Kay, MD, John C. Byrd, MD, Jennifer R Brown, MD, PhD, Kanti R. Rai, M.D., Thomas J. Kipps, M.D., Ph.D, Nicholas Chiorazzi, M.D.
Journal: Blood
Blood (2011) 118 (21): 288.
https://doi.org/10.1182/blood.V118.21.288.288
Published: 2011