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Sean Lang
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Journal Articles

Maternal Anti-Platelet β3 Integrin Antibodies Impair Angiogenesis and Cause Intracranial Hemorrhage in Fetal and Neonatal Alloimmune Thrombocytopenia

Yougbare Issaka, PhD, Sean Lang, MSc, Hong Yang, MD, Pingguo Chen, MD PhD, Xu Zhao, MD, Wei-She Tai, BSc, Darko Zdravic, MSc, Brian Vadasz, BSc, Conglei Li, MD PhD, Siavash Piran, MD, Alexandra H. Marshall, MSc, Guangheng Zhu, MD, Heidi Tiller, PhD, Mette Kjaer Killie, PhD, Shelley Boyd, MD, Howard Leong-Poi, MD, Bjorn Skogen, MD PhD, S. Lee Adamson, PhD, John Freedman, Heyu Ni, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2772.
https://doi.org/10.1182/blood.V124.21.2772.2772
Published: 2014
Journal Articles

Desialylation: A Novel Platelet Clearance Mechanism and a Potential New Therapeutic Target in Anti-GPIb Antibody Mediated Thrombocytopenia

Dianne E. van Der Wal, PhD, Guangheng Zhu, MD, June Li, BSc, Brian Vadasz, BSc, Yougbare Issaka, PhD, Sean Lang, MSc, John Freedman, MD, Heyu Ni, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 265.
https://doi.org/10.1182/blood.V120.21.265.265
Published: 2012
Journal Articles

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy

Pingguo Chen, Conglei Li, Sean Lang, Guangheng Zhu, Adili Reheman, Christopher M. Spring, John Freedman, Heyu Ni
Journal: Blood
Blood (2010) 116 (18): 3660–3668.
https://doi.org/10.1182/blood-2010-05-284919
Published: 2010
Journal Articles

Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression

Hong Yang, Sean Lang, Zhimin Zhai, Ling Li, Walter H. A. Kahr, Pingguo Chen, Jelena Brkić, Christopher M. Spring, Matthew J. Flick, Jay L. Degen, John Freedman, Heyu Ni
Journal: Blood
Blood (2009) 114 (2): 425–436.
https://doi.org/10.1182/blood-2008-03-145821
Published: 2009
Journal Articles

Engagement of Fibrinogen and β3 Integrin Is Required for Maintenance of Platelet Intracellular and Cell Surface P-Selectin Expression

Hong Yang, MD, Sean Lang, BSc, Zhimin Zhai, MD, Christopher M. Spring, MSc, Adili Reheman, MD, Pingguo Chen, PhD, Matthew J. Flick, PhD, Jay L. Degen, PhD, Ling Li, MSc, Walter H.A. Kahr, MD, PhD, John Freedman, MD, Heyu Ni, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2868.
https://doi.org/10.1182/blood.V112.11.2868.2868
Published: 2008
Journal Articles

Maternal Immune Response to Fetal Platelet GPIbα Causes More Frequent Miscarriage in An Animal Model: A Potential Explanation for Low Reported Incidence of Fetal and Neonatal Immune Thrombocytopenia Mediated by Anti-GPIbα Antibodies.

Conglei Li, MD, Siavash Piran, MSc., Pingguo Chen, PhD, Sean Lang, BSc., Jerry Ware, PhD, Zaverio M. Ruggeri, MD, John Freedman, MD, Heyu Ni, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3426.
https://doi.org/10.1182/blood.V112.11.3426.3426
Published: 2008