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Journal Articles

in Philadelphia-Chromosome-Negative Acute Lymphoblastic Leukemia, Late Relapses Are Not Uncommon, Occur Mostly in Patients at Standard Risk and Have a Relatively Favorable Outcome. Results of the International ALL Trial: MRC Ukallxii/ECOG E2993

Chezi Ganzel, Wang Xin Victoria, Adele K. Fielding, MB, BS, PhD, Jacob M. Rowe, MD, Susan M Richards, PhD, Georgina Buck, Rajesh Chopra, PhD, I. Jill Durrant, David Marks, MD PhD, Ian M. Franklin, MD, Andrew K McMilan, Mark R Litzow, MD, Elisabeth Paietta, PhD, Selina Luger, MD, Peter H Wiernik, Dan Douer, MD, Hillard M. Lazarus, MD, Martin S Tallman, MD, Anthony H. Goldstone, FRCP, FRCPath

Blood (2015) 126 (23): 795.

https://doi.org/10.1182/blood.V126.23.795.795

Published: 2015

Journal Articles

UKALL 2003, A Randomised Trial Investigating Treatment Intensification for Children and Young Adults with Minimal Residual Disease Defined High Risk Acute Lymphoblastic Leukaema

Ajay J Vora, FRCPath, Nicholas Goulden, FRCPath, Christopher D Mitchell, FRCPCH, Rachael Hough, FRCPath, Clare Rowntree, FRCPath, Susan M Richards, Ph.D

Blood (2012) 120 (21): 136.

https://doi.org/10.1182/blood.V120.21.136.136

Published: 2012

Journal Articles

Integrative Genome-Wide DNA Methylation and Gene Expression Analysis Reveals Biological and Clinical Insights In Adult Acute Lymphoblastic Leukemia

Huimin Geng, PhD, Donna Neuberg, ScD, Elisabeth Paietta, PhD, Xutao Deng, PhD, Yushan Li, Yuan Xin, Janis Racevskis, PhD, Rhett Ketterling, MD, Susan M Richards, PhD, Martin S. Tallman, MD, Jacob M. Rowe, MD, Mark R. Litzow, MD, Olivier Elemento, PhD, Ari M. Melnick

Blood (2010) 116 (21): 852.

https://doi.org/10.1182/blood.V116.21.852.852

Published: 2010

Journal Articles

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL): Results From the International MRC/ECOG Trial

Jonathan I Sive, MBChB, Georgina Buck, Adele Fielding, MBBS, PhD, FRCPath, FRCP, Hillard M. Lazarus, MD, FACP, Mark R. Litzow, MD, Selina Luger, MD, David I. Marks, MBBS, PHD, Andrew McMillan, FRCP, FRCPath, PhD, Susan M Richards, PhD, Jacob M. Rowe, Martin S. Tallman, MD, Anthony H. Goldstone, FRCP, FRCPath

Blood (2010) 116 (21): 493.

https://doi.org/10.1182/blood.V116.21.493.493

Published: 2010

Journal Articles

Imatinib Significantly Enhances Long-Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia; Final Results of the UKALLXII/ECOG2993 Trial

Adele K. Fielding, MBBS, PhD, FRCPath, FRCP, Georgina Buck, Hillard M. Lazarus, MD, FACP, Mark R. Litzow, MD, Selina Luger, MD, David I. Marks, MBBS, PHD, Andrew McMillan, FRCP, FRCPath, PhD, Anthony V. Moorman, PhD, Elisabeth Paietta, PhD, Susan M Richards, PhD, Martin S. Tallman, MD, Jacob M. Rowe, Anthony H. Goldstone, FRCP, FRCPath

Blood (2010) 116 (21): 169.

https://doi.org/10.1182/blood.V116.21.169.169

Published: 2010

Journal Articles

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia (B-ALL) Patients (pts) From the International UKALLXII/E2993 Trial: No Difference In Results Between B Cell Immunophenotypic Subgroups

Mark R. Litzow, MD, Georgina Buck, Gordon Dewald, Adele Fielding, MBBS, PhD, FRCPath, FRCP, Rhett Ketterling, Hillard M. Lazarus, MD, FACP, Selina Luger, MD, David I. Marks, MBBS, PHD, Andrew McMillan, FRCP, FRCPath, PhD, Anthony V. Moorman, PhD, Elisabeth Paietta, PhD, Susan M Richards, PhD, Jacob M. Rowe, Martin S. Tallman, MD, Anthony H. Goldstone, FRCP, FRCPath

Blood (2010) 116 (21): 524.

https://doi.org/10.1182/blood.V116.21.524.524

Published: 2010

Journal Articles

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

David I. Marks, Elisabeth M. Paietta, Anthony V. Moorman, Susan M. Richards, Georgina Buck, Gordon DeWald, Adolfo Ferrando, Adele K. Fielding, Anthony H. Goldstone, Rhett P. Ketterling, Mark R. Litzow, Selina M. Luger, Andrew K. McMillan, Marc R. Mansour, Jacob M. Rowe, Martin S. Tallman, Hillard M. Lazarus

Blood (2009) 114 (25): 5136–5145.

https://doi.org/10.1182/blood-2009-08-231217

Published: 2009

Journal Articles

WT1 mutations in T-ALL

Blood (2009) 114 (5): 1038–1045.

https://doi.org/10.1182/blood-2008-12-192039

Published: 2009

Includes: Supplemental data

Journal Articles

Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993

Adele K. Fielding, Jacob M. Rowe, Susan M. Richards, Georgina Buck, Anthony V. Moorman, I. Jill Durrant, David I. Marks, Andrew K. McMillan, Mark R. Litzow, Hillard M. Lazarus, Letizia Foroni, Gordon Dewald, Ian M. Franklin, Selina M. Luger, Elisabeth Paietta, Peter H. Wiernik, Martin S. Tallman, Anthony H. Goldstone

Blood (2009) 113 (19): 4489–4496.

https://doi.org/10.1182/blood-2009-01-199380

Published: 2009

Journal Articles

Standard Consolidation/Maintenance Chemotherapy Is Consistently Superior to a Single Autologous Transplant for Adult Patients with Acute Lymphoblastic Leukemia: Results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

Jacob M. Rowe, MD, Georgina Buck, Anthony V Moorman, MD, Martin S Tallman, MD, Susan M Richards, Ph.D, Adele K Fielding, MD, Ph.D, Alan K. Burnett, MD, FRCP, Ian M Franklin, MD, Peter H. Wiernik, MD, Hillard M Lazarus, MD, Elisabeth Paietta, PhD, Mark R. Litzow, MD, David I Marks, MD, Selina Luger, MD, Gordon W. Dewald, PhD, PhD, FACMG, Anthony H. Goldstone, FRCP, FRCPath

Blood (2008) 112 (11): 3314.

https://doi.org/10.1182/blood.V112.11.3314.3314

Published: 2008

Journal Articles

Response: Chemotherapy or allografting for young adults with high-risk ALL?

Anthony H. Goldstone, Susan M. Richards, Adele K. Fielding, Jacob M. Rowe

Blood (2008) 111 (12): 5755.

https://doi.org/10.1182/blood-2008-04-149088

Published: 2008

Journal Articles

In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

Anthony H. Goldstone, Susan M. Richards, Hillard M. Lazarus, Martin S. Tallman, Georgina Buck, Adele K. Fielding, Alan K. Burnett, Raj Chopra, Peter H. Wiernik, Letizia Foroni, Elisabeth Paietta, Mark R. Litzow, David I. Marks, Jill Durrant, Andrew McMillan, Ian M. Franklin, Selina Luger, Niculae Ciobanu, Jacob M. Rowe

Blood (2008) 111 (4): 1827–1833.

https://doi.org/10.1182/blood-2007-10-116582

Published: 2008

Includes: Supplemental data

Journal Articles

Characterization of in vitro antimurine thymocyte globulin–induced regulatory T cells that inhibit graft-versus-host disease in vivo

Melanie C. Ruzek, James S. Waire, Deborah Hopkins, Gina LaCorcia, Jennifer Sullivan, Bruce L. Roberts, Susan M. Richards, Sharon R. Nahill, John M. Williams, Abraham Scaria, John Dzuris, Srinivas Shankara, Richard D. Garman

Blood (2008) 111 (3): 1726–1734.

https://doi.org/10.1182/blood-2007-08-106526

Published: 2008

Journal Articles

Anti-Murine Thymocyte Globulin Prevents Acute Graft-Versus-Host Disease and Induces Foxp3+ T Cells in Target Organs.

Melanie C. Ruzek, PhD, James S. Waire, M.S., William Weber, B.S., John M. Williams, Ph.D., Susan M. Richards, Ph.D., Richard D. Garman, Ph.D.

Blood (2007) 110 (11): 3251.

https://doi.org/10.1182/blood.V110.11.3251.3251

Published: 2007

Journal Articles

Does Imatinib Change the Outcome in Philapdelphia Chromosome Positive Acute Lymphoblastic Leukaemia in Adults? Data from the UKALLXII/ECOG2993 Study.

Adele K. Fielding, MBBS, PhD, Susan M. Richards, PhD, Hillard M. Lazarus, MD, Mark R. Litzow, MD, Selina M. Luger, MD, David I. Marks, MBBS, PhD, Andrew K. McMillan, MBBS, PhD, Jacob M. Rowe, MD, Martin S. Tallman, MD, Anthony H. Goldstone, MD

Blood (2007) 110 (11): 8.

https://doi.org/10.1182/blood.V110.11.8.8

Published: 2007

Journal Articles

In Adults with Standard-Risk Acute Lymphoblastic Leukemia (ALL) the Greatest Benefit Is Achieved from an Allogeneic Transplant in First Complete Remission (CR) and an Autologous Transplant Is Less Effective Than Conventional Consolidation/Maintenance Chemotherapy: Final Results of the International ALL Trial (MRC UKALL XII/ECOG E2993).

Jacob M. Rowe, MD, Georgina Buck, PhD, Adele Fielding, MD, Martin S. Tallman, MD, Alan K. Burnett, MD, Raj Chopra, MD, Peter H. Wiernik, MD, Susan M. Richards, PhD, Hillard M. Lazarus, MD, Letizia Foroni, MD, Elisabeth Paietta, PhD, Mark R. Litzow, MD, David Marks, MD, Jill Durrant, MD, Anthony H. Goldstone, MD

Blood (2006) 108 (11): 2.

https://doi.org/10.1182/blood.V108.11.2.2

Published: 2006

Journal Articles

Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21)

Anthony V. Moorman, Susan M. Richards, Hazel M. Robinson, Jon C. Strefford, Brenda E. S. Gibson, Sally E. Kinsey, Tim O. B. Eden, Ajay J. Vora, Christopher D. Mitchell, Christine J. Harrison, on behalf of the UK Medical Research Council (MRC)/National Cancer Research Institute (NCRI) Childhood Leukaemia Working Party (CLWP)

Blood (2006) 109 (6): 2327–2330.

https://doi.org/10.1182/blood-2006-08-040436

Published: 2006

Includes: Supplemental data

Journal Articles

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study

Adele K. Fielding, Susan M. Richards, Rajesh Chopra, Hillard M. Lazarus, Mark R. Litzow, Georgina Buck, I. Jill Durrant, Selina M. Luger, David I. Marks, Ian M. Franklin, Andrew K. McMillan, Martin S. Tallman, Jacob M. Rowe, Anthony H. Goldstone, Medical Research Council of the United Kingdom Adult ALL Working Party and the Eastern Cooperative Oncology Group

Blood (2006) 109 (3): 944–950.

https://doi.org/10.1182/blood-2006-05-018192

Published: 2006

Journal Articles

Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993

Hillard M. Lazarus, Susan M. Richards, Raj Chopra, Mark R. Litzow, Alan K. Burnett, Peter H. Wiernik, Ian M. Franklin, Martin S. Tallman, Lucy Cook, Georgina Buck, I. Jill Durrant, Jacob M. Rowe, Anthony H. Goldstone, for the Medical Research Council (MRC)/National Cancer Research Institute (NCRI) Adult Leukaemia Working Party of the United Kingdom and the Eastern Cooperative Oncology Group

Blood (2006) 108 (2): 465–472.

https://doi.org/10.1182/blood-2005-11-4666

Published: 2006

Journal Articles

Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993

Jacob M. Rowe, Georgina Buck, Alan K. Burnett, Raj Chopra, Peter H. Wiernik, Susan M. Richards, Hillard M. Lazarus, Ian M. Franklin, Mark R. Litzow, Niculae Ciobanu, H. Grant Prentice, Jill Durrant, Martin S. Tallman, Anthony H. Goldstone, for ECOG and the MRC/NCRI Adult Leukemia Working Party

Blood (2005) 106 (12): 3760–3767.

https://doi.org/10.1182/blood-2005-04-1623

Published: 2005

NARROW

in Philadelphia-Chromosome-Negative Acute Lymphoblastic Leukemia, Late Relapses Are Not Uncommon, Occur Mostly in Patients at Standard Risk and Have a Relatively Favorable Outcome. Results of the International ALL Trial: MRC Ukallxii/ECOG E2993

UKALL 2003, A Randomised Trial Investigating Treatment Intensification for Children and Young Adults with Minimal Residual Disease Defined High Risk Acute Lymphoblastic Leukaema

Integrative Genome-Wide DNA Methylation and Gene Expression Analysis Reveals Biological and Clinical Insights In Adult Acute Lymphoblastic Leukemia

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL): Results From the International MRC/ECOG Trial

Imatinib Significantly Enhances Long-Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia; Final Results of the UKALLXII/ECOG2993 Trial

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia (B-ALL) Patients (pts) From the International UKALLXII/E2993 Trial: No Difference In Results Between B Cell Immunophenotypic Subgroups

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

WT1 mutations in T-ALL

Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993

Standard Consolidation/Maintenance Chemotherapy Is Consistently Superior to a Single Autologous Transplant for Adult Patients with Acute Lymphoblastic Leukemia: Results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

Response: Chemotherapy or allografting for young adults with high-risk ALL?

Characterization of in vitro antimurine thymocyte globulin–induced regulatory T cells that inhibit graft-versus-host disease in vivo

Anti-Murine Thymocyte Globulin Prevents Acute Graft-Versus-Host Disease and Induces Foxp3+ T Cells in Target Organs.

Does Imatinib Change the Outcome in Philapdelphia Chromosome Positive Acute Lymphoblastic Leukaemia in Adults? Data from the UKALLXII/ECOG2993 Study.

Prognosis of children with acute lymphoblastic leukemia (ALL) and intrachromosomal amplification of chromosome 21 (iAMP21)

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study

Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993

Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993

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