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Journal Articles

The Potent Dihydroorotate Dehydrogenase Inhibitor, Hosu-53, Exhibits Compelling Monotherapy Efficacy in Multiple Myeloma and Augments CD47 Targeted Therapy

Gerard Hilinski, Blaise Stearns, Sandip Vibhute, Tiffany Hughes, Susheela Tridandapani, Megan E. Johnstone, Thomas E. Goodwin, Jeffrey Patrick, Chad E. Bennett, Don Benson, John C. Byrd, Ola A. Elgamal, Erin K. Hertlein
Journal: Blood
Blood (2023) 142 (Supplement 1): 4692.
https://doi.org/10.1182/blood-2023-189238
Published: 2023
Journal Articles

CD56 Has a Critical Role in Regulating Multiple Myeloma Cell Growth and Response to Therapies

Francesca Cottini, Jose Rodriguez, Maxwell Birmingham, Tiffany Hughes, Nidhi Sharma, Gerard Lozanski, Bei Liu, Yiping Yang, Emanuele Cocucci, Don M Benson, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 889.
https://doi.org/10.1182/blood-2021-146370
Published: 2021
Journal Articles

Targeting the Mitotic Checkpoint in Myeloma with OSU-13, a Novel Mps1/Ttk Inhibitor

Larissa Valle Guilhen Longo, Betina McNeil-Laidley, Francesca Cottini, Tiffany Hughes, Gerald Hilinski, Elizabeth Merritt, Don M Benson, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 2660.
https://doi.org/10.1182/blood-2021-151124
Published: 2021
Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4395.
https://doi.org/10.1182/blood-2019-129699
Published: 2019
Journal Articles

Meta-Analysis Illustrates Role of Interferon-γ Signaling in Multiple Myeloma Pathogenesis

Jihad Aljabban, MMSc, BA, Nabeal Aljabban, BS, Mohamad Mukhtar, BS, Saad Syed, BS, Ross Wanner, BS, Francesca Cottini, MD, Tiffany Hughes, BS, PhD, Kareem Saleh, BS, Evan C Catton, Taylor Gonzalez, Maryam Panahiazar, PhD, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4510.
https://doi.org/10.1182/blood-2018-99-112265
Published: 2018
Journal Articles

Aryl Hydrocarbon Receptor (AHR) Antagonism As a Transformative, Dual-Mechanism Novel Therapy for Multiple Myeloma

Taylor Gonzalez, Evan C Catton, Ashley E. Rosko, MD, Yvonne Efebera, MD, Maria Chaudhry, MD, Francesca Cottini, MD, Bethany L Mundy-Bosse, PhD, Tiffany Hughes, BS, PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1933.
https://doi.org/10.1182/blood-2018-99-117465
Published: 2018
Journal Articles

Human AML activates the aryl hydrocarbon receptor pathway to impair NK cell development and function

Steven D. Scoville, Ansel P. Nalin, Luxi Chen, Li Chen, Michael H. Zhang, Kathleen McConnell, Susana Beceiro Casas, Gabrielle Ernst, Abd Al-Rahman Traboulsi, Naima Hashi, Monica Williams, Xiaoli Zhang, Tiffany Hughes, Anjali Mishra, Don M. Benson, Jennifer N. Saultz, Jianhua Yu, Aharon G. Freud, Michael A. Caligiuri, Bethany L. Mundy-Bosse
Journal: Blood
Blood (2018) 132 (17): 1792–1804.
https://doi.org/10.1182/blood-2018-03-838474
Published: 2018
Includes: Supplemental data
Journal Articles

Combination Therapy with Daratumumab and CAR-NK Targeting CS1 for Multiple Myeloma

Yibo Zhang, PhD, Lichao Chen, Yufeng Wang, Xinxin Li, Tiffany Hughes, Hans Klingemann, Don M Benson, MD PhD, Jianhua Yu, PhD
Journal: Blood
Blood (2016) 128 (22): 1342.
https://doi.org/10.1182/blood.V128.22.1342.1342
Published: 2016
Journal Articles

Microrna 29b Mediates Immune Evasion of Natural Killer Cells in Acute Myeloid Leukemia

Steven Scoville, BS, Bethany Mundy-Bosse, PhD, Michael Zhang, Li Chen, Ryan Sanderson, Tiffany Hughes, BS, PhD, Ramiro Garzon, MD, Anjali Mishra, PhD, Stefan Costinean, Carlo M. Croce, MD, Aharon G. Freud, MD PhD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2015) 126 (23): 207.
https://doi.org/10.1182/blood.V126.23.207.207
Published: 2015
Journal Articles

MicroRNAs activate natural killer cells through Toll-like receptor signaling

Shun He, Jianhong Chu, Lai-Chu Wu, Hsiaoyin Mao, Yong Peng, Christopher A. Alvarez-Breckenridge, Tiffany Hughes, Min Wei, Jianying Zhang, Shunzong Yuan, Sumeet Sandhu, Sumithira Vasu, Don M. Benson, Jr, Craig C. Hofmeister, Xiaoming He, Kalpana Ghoshal, Steven M. Devine, Michael A. Caligiuri, Jianhua Yu
Journal: Blood
Blood (2013) 121 (23): 4663–4671.
https://doi.org/10.1182/blood-2012-07-441360
Published: 2013
Includes: Supplemental data
Journal Articles

CD94 surface density identifies a functional intermediary between the CD56 bright and CD56 dim human NK-cell subsets

Jianhua Yu, Hsiaoyin C. Mao, Min Wei, Tiffany Hughes, Jianying Zhang, Il-kyoo Park, Shujun Liu, Susan McClory, Guido Marcucci, Rossana Trotta, Michael A. Caligiuri
Journal: Blood
Blood (2010) 115 (2): 274–281.
https://doi.org/10.1182/blood-2009-04-215491
Published: 2010
Includes: Supplemental data
Journal Articles

Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the T H 17 cytokine interleukin-22

Brief Report
Tiffany Hughes, Brian Becknell, Susan McClory, Edward Briercheck, Aharon G. Freud, Xiaoli Zhang, Hsiaoyin Mao, Gerard Nuovo, Jianhua Yu, Michael A. Caligiuri
Journal: Blood
Blood (2009) 113 (17): 4008–4010.
https://doi.org/10.1182/blood-2008-12-192443
Published: 2009
Includes: Supplemental data
Journal Articles

Efficient and Reproducible Retroviral Infection of Primary Human Natural Killer Cells.

Brian Becknell, Rossana Trotta, Jianhua Yu, Wei Ding, Hsiaoyin C. Mao, Tiffany Hughes, Trent Marburger, Michael A. Caligiuri
Journal: Blood
Blood (2004) 104 (11): 1348.
https://doi.org/10.1182/blood.V104.11.1348.1348
Published: 2004
Journal Articles

Elucidation of the Molecular Mechanisms by Which Inflammatory and Anti-Inflammatory Monokines Regulate Interferon (IFN)- γ Production.

Jianhua Yu, Brian Becknell, Shujun Liu, Rossana Trotta, Micheal S. Jaung, Tiffany Hughes, Guido Marcucci, Michael B. Weinstein, Michael A. Caligiuri
Journal: Blood
Blood (2004) 104 (11): 111.
https://doi.org/10.1182/blood.V104.11.111.111
Published: 2004