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Journal Articles

Initial Results in a Phase 1b Trial of PB-04 in Sickle Cell Disease Demonstrate Fetal Hemoglobin Induction, Additive Activity with Hydroxyurea, and Improved Red Blood Cell Sickling Parameters

Kevin H.M. Kuo, Sylvia Titi Singer, Gershwin Theophilus Blyden, Lanetta Bronté-Hall, Aidan Faller, Abdullah Kutlar, Frans A. Kuypers, Aliya U. Zaidi, Patrick C. Hines, Niren Patel, Sandra Larkin, Hanny Al-Samkari, Sujit Sheth, Seyed Mehdi Nouraie, Susan Perrine

Blood (2023) 142 (Supplement 1): 1148.

https://doi.org/10.1182/blood-2023-184627

Published: 2023

Journal Articles

Three Distinct Groups of Phenotype Severity in Beta-Thalassemia

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-139196

Published: 2020

Journal Articles

Development of a Severity Score System for Thalassemia Syndromes

Blood (2019) 134 (Supplement_1): 2225.

https://doi.org/10.1182/blood-2019-124675

Published: 2019

Journal Articles

Pituitary Iron: Effect on Pituitary Volume and Function in Transfusion Dependent Thalassemia

Sylvia Titi Titi Singer, MD, Roland Fischer, PhD, Qing Yuan, PhD, Ashutosh Lal, MD, Isabel E Allen, PhD, Elliott Vichinsky, MD, Zhiyue J Wang, PhD

Blood (2017) 130 (Supplement 1): 3502.

https://doi.org/10.1182/blood.V130.Suppl_1.3502.3502

Published: 2017

Journal Articles

Abnormal Reproductive Measures and Seminal Plasma Findings in Men With Thalassemia Major (TM) and Iron Overload

Sylvia Titi Singer, MD, Jerry Wang, MD, Jung H Suh, PhD, David Killelea, PhD, Kristen Ivani, PhD, Olivia Oliveros, Qing Yuan, PhD, Elliott Vichinsky, MD, James Smith, MD

Blood (2013) 122 (21): 4707.

https://doi.org/10.1182/blood.V122.21.4707.4707

Published: 2013

Journal Articles

Sildenafil Therapy in Patients with Thalassemia and an Elevated Tricuspid Regurgitant Jet Velocity (TRV) On Doppler Echocardiography At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network

Claudia R. Morris, MD, Hae-Young Kim, DrPH, John C Wood, MD, Felicia Trachtenberg, PhD, Elizabeth S Klings, MD, John B. Porter, MD, Nancy Sweeters, RN, PNP, Nancy F Olivieri, MD, Janet L. Kwiatkowski, MD, Sylvia Titi Singer, MD, Ali T Taher, MD, Ellis J. Neufeld, MD, PhD, Alexis A. Thompson, MD, MPH, Vandana Sachdev, M.D., Sandra K Larkin, MS, Jung H Suh, PhD, Frans A Kuypers, PhD, Elliott Vichinsky, MD

Blood (2012) 120 (21): 1023.

https://doi.org/10.1182/blood.V120.21.1023.1023

Published: 2012

Journal Articles

Cardiopulmonary and Laboratory Profiling of Patients with Thalassemia At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network.

Claudia R. Morris, MD, Hae-Young Kim, DrPH, John C Wood, MD, Ph.D, Felicia Trachtenberg, PhD, Elizabeth S Klings, MD, John B. Porter, MD, Nancy Sweeters, RN, PNP, Nancy F Olivieri, MD, Janet L. Kwiatkowski, MD, Sylvia Titi Singer, MD, Ali T Taher, MD, Ellis J. Neufeld, MD, PhD, Alexis A. Thompson, MD, MPH, Sandra K Larkin, MS, Jung H Suh, PhD, Elliott Vichinsky, MD, Frans A Kuypers, PhD

Blood (2012) 120 (21): 2122.

https://doi.org/10.1182/blood.V120.21.2122.2122

Published: 2012

Journal Articles

Longitudinal Follow-up From Newborn Screening Reveals Deletional Hemoglobin H Disease and Hemoglobin H Constant Spring Disease Are Distinct Thalassemia Syndromes

Ashutosh Lal, MD, Michael Lee Goldrich, BS, Drucilla Foote, PNP, Mahin Azimi, MS, Sylvia Titi Singer, Elliott Vichinsky, MD

Blood (2010) 116 (21): 4260.

https://doi.org/10.1182/blood.V116.21.4260.4260

Published: 2010

Journal Articles

Hemoglobin H-Constant Spring in North America: A Common Alpha Thalassemia with Frequent Complications.

Titi Singer, Hae-Young Kim, Nancy F Olivieri, Janet Kwiatkowski, Ashutosh Lal, Thomas D. Coates, Susan Carson, Melody J. Cunningham, Patricia J Giardina, Brigitta U Mueller, Charles Quinn, Elliott Vichinsky, Thalassemia Clinical Research Network

Blood (2008) 112 (11): 1880.

https://doi.org/10.1182/blood.V112.11.1880.1880

Published: 2008

Journal Articles

Body Composition and Its Relationship to Growth and Bone Mass in Patients with Thalassemia

Ellen Fung, PhD, Yan Xu, PhD, Janet Kwiatkowski, MD, Sylvia Titi Singer, MD, Ashutosh Lal, Maria G Vogiatzi, Nancy F. Olivieri, MD, Ellis J. Neufeld, Elliott Vichinsky, MD, Patricia Giardina, MD

Blood (2008) 112 (11): 3890.

https://doi.org/10.1182/blood.V112.11.3890.3890

Published: 2008

Journal Articles

MRI Assessment of Pituitary Iron and Volume in Thalassemia, and Relation to Hypothalamic-Pituitary-Gonadal Axis Function (HPG): A Feasibility Study.

Zhiyue J. Wang, PhD, Roland Fischer, PhD, Ellen Butensky, PhD, PNP, Lynne Neumayr, MD, Sylvia Titi Singer, MD, Phillip Lee, MD, Zili Chu, PhD, Jill V. Hunter, MD, John Firebaugh, Elliott Vichinsky, MD, Paul Harmatz, MD

Blood (2006) 108 (11): 1778.

https://doi.org/10.1182/blood.V108.11.1778.1778

Published: 2006

Journal Articles

Dysregulated Arginine Metabolism and Elevated Arginase Activity in Thalassemia.

Claudia R. Morris, MD, Frans A. Kuypers, PhD, Greg Kato, MD, Jennifer Gardner, Sandy Larkin, MS, Titi Singer, MD, Elliott Vichinsky, MD

Blood (2005) 106 (11): 3644.

https://doi.org/10.1182/blood.V106.11.3644.3644

Published: 2005

Journal Articles

Utility of Holter Electrocardiogram Monitoring in Iron over Loaded β Thalassemia and Sickle Cell Disease.

Naveen Qureshi, MD, Kishor Avasarala, MD, Sylvia Titi Singer, MD, Drucilla Foote, PNP, Ekua Hackney-Stephens, PNP, Robert Hagar, MD, Elliott P. Vichinsky, MD

Blood (2004) 104 (11): 3784.

https://doi.org/10.1182/blood.V104.11.3784.3784

Published: 2004

Journal Articles

The Outcomes of Preimplantation Genetic Diagnosis Therapy in Treatment of β Thalassemia - a Retrospective Analysis.

Naveen Qureshi, MD, Drucilla Foote, PNP, Rebecca Madore, Mark C. Walters, MD, Sylvia Titi Singer, MD, Keith C. Quirolo, MD, Elliott P. Vichinsky, MD

Blood (2004) 104 (11): 3783.

https://doi.org/10.1182/blood.V104.11.3783.3783

Published: 2004

Journal Articles

Pulmonary Hypertension: A Common Complication in Thalassemia.

Elliott P. Vichinsky, MD, Claudia R. Morris, MD, Ward Hagar, MD, Jennifer Gardner, Sylvia Titi Singer, MD, Drucilla Foote, PNP, Keith C. Quirolo, MD

Blood (2004) 104 (11): 3612.

https://doi.org/10.1182/blood.V104.11.3612.3612

Published: 2004

Journal Articles

Biotin-Labeled RBC Survival in Thalassemia and Impact of Treatment.

Sylvia Titi Singer, MD, Nancy E. Olivieri, MD, Nancy Sweeters, PNP, Carmen Rodwell, MD, Christina Oliver, Elliott P. Vichinsky, MD, Frans A. Kuypers, PhD

Blood (2004) 104 (11): 3616.

https://doi.org/10.1182/blood.V104.11.3616.3616

Published: 2004

Journal Articles

Pulmonary Hypertension in Thalassemia: Association with Platelet Activation and Hypercoagulable State.

Sylvia Titi Singer, MD, Howard Rosenfeld, MD, Elliott Vichinsky, MD

Blood (2004) 104 (11): 3618.

https://doi.org/10.1182/blood.V104.11.3618.3618

Published: 2004

NARROW

Initial Results in a Phase 1b Trial of PB-04 in Sickle Cell Disease Demonstrate Fetal Hemoglobin Induction, Additive Activity with Hydroxyurea, and Improved Red Blood Cell Sickling Parameters

Three Distinct Groups of Phenotype Severity in Beta-Thalassemia

Development of a Severity Score System for Thalassemia Syndromes

Pituitary Iron: Effect on Pituitary Volume and Function in Transfusion Dependent Thalassemia

Abnormal Reproductive Measures and Seminal Plasma Findings in Men With Thalassemia Major (TM) and Iron Overload

Sildenafil Therapy in Patients with Thalassemia and an Elevated Tricuspid Regurgitant Jet Velocity (TRV) On Doppler Echocardiography At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network

Cardiopulmonary and Laboratory Profiling of Patients with Thalassemia At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network.

Longitudinal Follow-up From Newborn Screening Reveals Deletional Hemoglobin H Disease and Hemoglobin H Constant Spring Disease Are Distinct Thalassemia Syndromes

Hemoglobin H-Constant Spring in North America: A Common Alpha Thalassemia with Frequent Complications.

Body Composition and Its Relationship to Growth and Bone Mass in Patients with Thalassemia

MRI Assessment of Pituitary Iron and Volume in Thalassemia, and Relation to Hypothalamic-Pituitary-Gonadal Axis Function (HPG): A Feasibility Study.

Dysregulated Arginine Metabolism and Elevated Arginase Activity in Thalassemia.

Utility of Holter Electrocardiogram Monitoring in Iron over Loaded β Thalassemia and Sickle Cell Disease.

The Outcomes of Preimplantation Genetic Diagnosis Therapy in Treatment of β Thalassemia - a Retrospective Analysis.

Pulmonary Hypertension: A Common Complication in Thalassemia.

Biotin-Labeled RBC Survival in Thalassemia and Impact of Treatment.

Pulmonary Hypertension in Thalassemia: Association with Platelet Activation and Hypercoagulable State.

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American Society of Hematology

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American Society of Hematology

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