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Journal Articles

B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C δ

Elisabeth Salzer, Elisangela Santos-Valente, Stefanie Klaver, Sol A. Ban, Wolfgang Emminger, Nina Kathrin Prengemann, Wojciech Garncarz, Leonhard Müllauer, Renate Kain, Heidrun Boztug, Andreas Heitger, Klaus Arbeiter, Franz Eitelberger, Markus G. Seidel, Wolfgang Holter, Arnold Pollak, Winfried F. Pickl, Elisabeth Förster-Waldl, Kaan Boztug

Blood (2013) 121 (16): 3112–3116.

https://doi.org/10.1182/blood-2012-10-460741

Published: 2013

Includes: Supplemental data

Journal Articles

CD19 + CD21 low B cells and patients at risk for NIH-defined chronic graft-versus-host disease with bronchiolitis obliterans syndrome

Zoya Kuzmina, Katharina Krenn, Ventzislav Petkov, Ulrike Körmöczi, Roman Weigl, Arno Rottal, Peter Kalhs, Margit Mitterbauer, Lothar Ponhold, Gerhard Dekan, Hildegard T. Greinix, Winfried F. Pickl

Blood (2013) 121 (10): 1886–1895.

https://doi.org/10.1182/blood-2012-06-435008

Published: 2013

Includes: Supplemental data

Journal Articles

Effects of Ponatinib and Other Novel TKI On Growth, Survival, and Function of Neoplastic Eosinophils Carrying FIP1L1/Pdgfra

Irina Sadovnik, M.Sc., Peter Valent, MD, Els Lierman, PhD, Harald Herrmann, M.D., Barbara Peter, D.V.M., Verena Suppan, BSc, Gabriele Stefanzl, MSc, Winfried F Pickl, MD, Jan Cools, PhD, Peter Vandenberghe, MD, PhD

Blood (2012) 120 (21): 1760.

https://doi.org/10.1182/blood.V120.21.1760.1760

Published: 2012

Journal Articles

5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS- demethylation and FAS re-expression, and synergism with FAS-ligand

Viviane Ghanim, Harald Herrmann, Gerwin Heller, Barbara Peter, Emir Hadzijusufovic, Katharina Blatt, Karina Schuch, Sabine Cerny-Reiterer, Irina Mirkina, Heidrun Karlic, Winfried F. Pickl, Sabine Zöchbauer-Müller, Peter Valent

Blood (2012) 119 (18): 4242–4252.

https://doi.org/10.1182/blood-2011-09-382770

Published: 2012

Includes: Supplemental data

Journal Articles

5-Azacytidine and Decitabine Induce FAS Re-Expression, Exert Major Proapoptotic Effects, and Cooperate with the FAS Ligand in Producing Apoptosis in Neoplastic Human Mast Cells,

Viviane Ghanim, M.D., Harald Herrmann, MD, Emir Hadzijusufovic, DVM, Barbara Peter, D.V.M., Katharina Blatt, M.Sc., Karina Schuch, Sabine Cerny-Reiterer, D.V.M., Irina Mirkina, PhD, Gerwin Heller, PhD, Sabine Zöchbauer-Müller, MD, Heidrun Karlic, PhD, Winfried F Pickl, MD, Peter Valent, M.D.

Blood (2011) 118 (21): 3457.

https://doi.org/10.1182/blood.V118.21.3457.3457

Published: 2011

Journal Articles

The Heat Shock Protein 32 (Hsp32)/HO-1-Targeting Drug SMA-ZnPP and the Triterpenoid CDDO-Me Exert Synergistic Growth-Inhibitory Effects on TKI-Resistant Leukemic Cells in Ph+ CML

Karoline V. Gleixner, M.D., Harald Herrmann, M.D., Katharina Blatt, M.Sc., Winfried F Pickl, MD, Marina Konopleva, MD, PhD, Gahininath Y Bharate, Michael Andreeff, M.D., Ph.D., Hiroshi Maeda, MD, Peter Valent, M.D.

Blood (2011) 118 (21): 4414.

https://doi.org/10.1182/blood.V118.21.4414.4414

Published: 2011

Journal Articles

KIT-D816V–independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib

Karoline V. Gleixner, Matthias Mayerhofer, Sabine Cerny-Reiterer, Gregor Hörmann, Uwe Rix, Keiryn L. Bennett, Emir Hadzijusufovic, Renata A. Meyer, Winfried F. Pickl, Jason Gotlib, Hans-Peter Horny, Andreas Reiter, Gerlinde Mitterbauer-Hohendanner, Giulio Superti-Furga, Peter Valent

Blood (2011) 118 (7): 1885–1898.

https://doi.org/10.1182/blood-2010-06-289959

Published: 2011

Includes: Supplemental data

Journal Articles

Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification

Estella Matutes, Winfried F. Pickl, Mars van't Veer, Ricardo Morilla, John Swansbury, Herbert Strobl, Andishe Attarbaschi, Georg Hopfinger, Sue Ashley, Marie Christine Bene, Anna Porwit, Alberto Orfao, Petr Lemez, Richard Schabath, Wolf-Dieter Ludwig

Blood (2011) 117 (11): 3163–3171.

https://doi.org/10.1182/blood-2010-10-314682

Published: 2011

Journal Articles

Significant differences in B-cell subpopulations characterize patients with chronic graft-versus-host disease–associated dysgammaglobulinemia

Zoya Kuzmina, Hildegard T. Greinix, Roman Weigl, Ulrike Körmöczi, Arno Rottal, Sophie Frantal, Sandra Eder, Winfried F. Pickl

Blood (2011) 117 (7): 2265–2274.

https://doi.org/10.1182/blood-2010-07-295766

Published: 2011

Includes: Supplemental data

Journal Articles

Nilotinib and Dasatinib Produce Synergistic Growth-Inhibitory Effects In Imatinib-Resistant CML Cells, Including Subclones Bearing the Multi-Resistant BCR/ABL Mutant T315I

Karoline V. Gleixner, Harald Herrmann, Irina Sadovnik, Karina Schuch, Winfried F Pickl, Christian Sillaber, Peter Valent

Blood (2010) 116 (21): 2280.

https://doi.org/10.1182/blood.V116.21.2280.2280

Published: 2010

Journal Articles

The Multi-Kinase/ABL Inhibitor R763/AS703569 Induces DNA Endoreduplication and Apoptosis In Imatinib-Resistant CML Cells and Synergizes with Nilotinib, Dasatinib, and the Plk-1 Inhibitor BI 2536, In Producing Growth Inhibition.

Karoline V. Gleixner, Harald Herrmann, Barbara Peter, Katharina Blatt, Karina Schuch, Winfried F Pickl, Christian Sillaber, Peter Valent

Blood (2010) 116 (21): 3394.

https://doi.org/10.1182/blood.V116.21.3394.3394

Published: 2010

Journal Articles

Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs

Karl J. Aichberger, Karoline V. Gleixner, Irina Mirkina, Sabine Cerny-Reiterer, Barbara Peter, Veronika Ferenc, Michael Kneidinger, Christian Baumgartner, Matthias Mayerhofer, Alexander Gruze, Winfried F. Pickl, Christian Sillaber, Peter Valent

Blood (2009) 114 (26): 5342–5351.

https://doi.org/10.1182/blood-2008-08-175190

Published: 2009

Journal Articles

Bosutinib Blocks Lyn and Btk Activation and Synergizes with the KIT D816V-Targeting Drug Midostaurin in Inducing Apoptosis in Neoplastic Human Mast Cells.

Karoline Veronika Gleixner, MD, Matthias Mayerhofer, MD, Gregor Hörmann, Karina Schuch, Sabine Cerny-Reiterer, MD, Barbara Peter, M.V.M, Harald Herrmann, MD, Winfried F. Pickl, MD, Christian Sillaber, Peter Valent, MD

Blood (2009) 114 (22): 1717.

https://doi.org/10.1182/blood.V114.22.1717.1717

Published: 2009

Journal Articles

Assessment of the Potential of Immature CD19+CD21- B-Lymphocytes to Predict Response to Various Systemic Therapies in Chronic Graft-Versus-Host Disease.

Zoya Kuzmina, Hildegard Greinix, Roman Weigl, Sandra Eder, Robert Knobler, Ulrike Koermoeczi, Arno Rottal, Christoph C Zielinski, Winfried F. Pickl

Blood (2009) 114 (22): 2226.

https://doi.org/10.1182/blood.V114.22.2226.2226

Published: 2009

Journal Articles

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients

Katharina Pfistershammer, Anita Lawitschka, Christoph Klauser, Judith Leitner, Roman Weigl, Mirjam H. M. Heemskerk, Winfried F. Pickl, Otto Majdic, Georg A. Böhmig, Gottfried F. Fischer, Hildegard T. Greinix, Peter Steinberger

Blood (2009) 114 (11): 2323–2332.

https://doi.org/10.1182/blood-2008-10-183814

Published: 2009

Includes: Supplemental data

Journal Articles

Proportions of immature CD19 + CD21 − B lymphocytes predict the response to extracorporeal photopheresis in patients with chronic graft-versus-host disease

Zoya Kuzmina, Hildegard T. Greinix, Robert Knobler, Nina Worel, Michal Kouba, Roman Weigl, Ulrike Körmöczi, Arno Rottal, David Pohlreich, Christoph Zielinski, Winfried F. Pickl

Blood (2009) 114 (3): 744–746.

https://doi.org/10.1182/blood-2009-05-221028

Published: 2009

Journal Articles

Leukemic challenge unmasks a requirement for PI3Kδ in NK cell–mediated tumor surveillance

Eva Zebedin, Olivia Simma, Christian Schuster, Eva Maria Putz, Sabine Fajmann, Wolfgang Warsch, Eva Eckelhart, Dagmar Stoiber, Eva Weisz, Johannes A. Schmid, Winfried F. Pickl, Christian Baumgartner, Peter Valent, Roland P. Piekorz, Michael Freissmuth, Veronika Sexl

Blood (2008) 112 (12): 4655–4664.

https://doi.org/10.1182/blood-2008-02-139105

Published: 2008

Includes: Supplemental data

Journal Articles

Effects of Bosutinib (SKI-606) in CML: Kinase Target Profile, Effects on BCR/ABL Mutants, and Synergism with Dasatinib in T315I+ Cells

Karoline Veronika Gleixner, MD, Lily L Remsing Rix, Christian Baumgartner, Uwe Rix, Alexander Gruze, Renata Anna Meyer, M.D., Winfried F. Pickl, MD, Christian Sillaber, Martin Augustin, Jeff Till, Giulio Superti-Furga, Peter Valent, MD

Blood (2008) 112 (11): 3195.

https://doi.org/10.1182/blood.V112.11.3195.3195

Published: 2008

Journal Articles

Identification of Heat Shock Protein 32 (Hsp32) as a Novel Target in Acute Lymphoblastic Leukemia (ALL).

Renata A. Meyer, MD, Harald Herrmann, MD, Karoline V. Gleixner, MD, Alexander Gruze, Sabine Cerny-Reiterer, MD, Rainer Hubmann, PhD, Medhat Shehata, MD, Matthias Mayerhofer, MD, Wolfgang R. Sperr, MD, Winfried F. Pickl, MD, Junia V. Melo, PhD, Gahininath Y. Bharate, Ulrich Jäger, MD, Hiroshi Maeda, MD, PhD, Peter Valent, MD

Blood (2008) 112 (11): 1616.

https://doi.org/10.1182/blood.V112.11.1616.1616

Published: 2008

Journal Articles

Effects of the Mcl-1/Bcl-2 Inhibitor GX015-070 (Obatoclax ® ) on Growth and Viability of Canine and Human Neoplastic Mast Cells

Barbara Peter, MVM, Karl J. Aichberger, MD, Karoline V. Gleixner, MD, Veronika Ferenc, MD, Alexander Gruze, Winfried F. Pickl, MD, Michael Willmann, DVM, Peter Valent, MD

Blood (2008) 112 (11): 861.

https://doi.org/10.1182/blood.V112.11.861.861

Published: 2008

NARROW

B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C δ

CD19 + CD21 low B cells and patients at risk for NIH-defined chronic graft-versus-host disease with bronchiolitis obliterans syndrome

Effects of Ponatinib and Other Novel TKI On Growth, Survival, and Function of Neoplastic Eosinophils Carrying FIP1L1/Pdgfra

5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS- demethylation and FAS re-expression, and synergism with FAS-ligand

5-Azacytidine and Decitabine Induce FAS Re-Expression, Exert Major Proapoptotic Effects, and Cooperate with the FAS Ligand in Producing Apoptosis in Neoplastic Human Mast Cells,

The Heat Shock Protein 32 (Hsp32)/HO-1-Targeting Drug SMA-ZnPP and the Triterpenoid CDDO-Me Exert Synergistic Growth-Inhibitory Effects on TKI-Resistant Leukemic Cells in Ph+ CML

KIT-D816V–independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib

Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification

Significant differences in B-cell subpopulations characterize patients with chronic graft-versus-host disease–associated dysgammaglobulinemia

Nilotinib and Dasatinib Produce Synergistic Growth-Inhibitory Effects In Imatinib-Resistant CML Cells, Including Subclones Bearing the Multi-Resistant BCR/ABL Mutant T315I

The Multi-Kinase/ABL Inhibitor R763/AS703569 Induces DNA Endoreduplication and Apoptosis In Imatinib-Resistant CML Cells and Synergizes with Nilotinib, Dasatinib, and the Plk-1 Inhibitor BI 2536, In Producing Growth Inhibition.

Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs

Bosutinib Blocks Lyn and Btk Activation and Synergizes with the KIT D816V-Targeting Drug Midostaurin in Inducing Apoptosis in Neoplastic Human Mast Cells.

Assessment of the Potential of Immature CD19+CD21- B-Lymphocytes to Predict Response to Various Systemic Therapies in Chronic Graft-Versus-Host Disease.

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients

Proportions of immature CD19 + CD21 − B lymphocytes predict the response to extracorporeal photopheresis in patients with chronic graft-versus-host disease

Leukemic challenge unmasks a requirement for PI3Kδ in NK cell–mediated tumor surveillance

Effects of Bosutinib (SKI-606) in CML: Kinase Target Profile, Effects on BCR/ABL Mutants, and Synergism with Dasatinib in T315I+ Cells

Identification of Heat Shock Protein 32 (Hsp32) as a Novel Target in Acute Lymphoblastic Leukemia (ALL).

Effects of the Mcl-1/Bcl-2 Inhibitor GX015-070 (Obatoclax ® ) on Growth and Viability of Canine and Human Neoplastic Mast Cells

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American Society of Hematology

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American Society of Hematology

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