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Journal Articles

Higher Order Restrictions of the Immunoglobulin Repertoire in CLL: The Illustrative Case of Stereotyped Subsets #2 and #169

Katerina Gemenetzi, Andreas Agathangelidis, PhD, Fotis Psomopoulos, Karla Plevova, PhD, Lesley-Ann Sutton, Kostas Pasentsis, Achilles Anagnostopoulos, Raphael Sandaltzopoulos, Richard Rosenquist, MD PhD, Frederic Davi, MD PhD, Sarka Pospisilova, Prof PhD, Kostas Stamatopoulos, Anastasia Chatzidimitriou

Blood (2019) 134 (Supplement_1): 5453.

https://doi.org/10.1182/blood-2019-128017

Published: 2019

Journal Articles

KLF1 Mutations Are Not Common in Israel but Can Explain Occasional Cases of Elevated HbA2 or Very Elevated Fetal Hemoglobin

Deborah Rund, MD, Dvora Filon, PhD, Natalie Bloch Isenberg, MD, Neta Goldschmidt, MD

Blood (2018) 132 (Supplement 1): 3640.

https://doi.org/10.1182/blood-2018-99-113903

Published: 2018

Journal Articles

CLL Stereotyped Subset #4 Igs Acquire Binding to Viable B Lymphocyte Surfaces By Somatic Mutations, Isotype Class Switching, and with the Prerequisite of IG Self-Association

Yun Liu, MS, Rosa Catera, PhD, Chao Gao, PhD, Xiao J. Yan, MDPhD, Steven L. Allen, MD, Jonathan E. Kolitz, MD, Kanti Rai, MD, Charles C Chu, PhD, Ten Feizi, MD, Kostas Stamatopoulos, Nicholas Chiorazzi, MD

Blood (2017) 130 (Supplement 1): 58.

https://doi.org/10.1182/blood.V130.Suppl_1.58.58

Published: 2017

Journal Articles

Red Blood Cell-Encapsulation of L-Asparaginase Favorably Modulates Target Selectivity and Pharmacodynamics

Philip L Lorenzi, PhD, Thomas D Horvath, PhD, Leona A Martin, M.S., Wai Kin Chan, PhD, Di Du, PhD, David H. Hawke, PhD, John N Weinstein, MD,PhD, Kenneth J Swart, PhD, Iman El-Hariry, MD PhD

Blood (2016) 128 (22): 1266.

https://doi.org/10.1182/blood.V128.22.1266.1266

Published: 2016

Journal Articles

Involvement of Allele-Specific Methylation of Asparagine Synthetase Gene in Asparaginase Sensitivity of BCP-ALL

Atsushi Watanabe, MD PhD, Takeshi Inukai, MD, PhD, Minori Tamai, MD PhD, Tamao Shinohara, MD, Shinpei Somazu, MD, Hiroko Oshiro, MD PhD, Koshi Akahane, MD PhD, Kumiko Goi, MD,PhD, Kunio Miyake, PhD, Kevin Urayama, PhD MPH, Kanji Sugita, MD, PhD

Blood (2016) 128 (22): 3966.

https://doi.org/10.1182/blood.V128.22.3966.3966

Published: 2016

Journal Articles

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem Cell Cycling

Daiki Karigane, MD, Shinichiro Okamoto, Toshio Suda, MD PhD, Keiyo Takubo, MD PhD

Blood (2015) 126 (23): 776.

https://doi.org/10.1182/blood.V126.23.776.776

Published: 2015

Journal Articles

Casein Kinase 1A1 (CSNK1A1) Is Recurrently Mutated in MDS Patients with Deletion of Chromosome 5q

Blood (2014) 124 (21): 4643.

https://doi.org/10.1182/blood.V124.21.4643.4643

Published: 2014

Journal Articles

Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe

Blood (2014) 124 (21): 92.

https://doi.org/10.1182/blood.V124.21.92.92

Published: 2014

Journal Articles

CITED2 Facilitates Apoptosis Induced By Histone Deacetylase Inhibitor SAHA In Human Pediatric Pre-B Acute Lymphoblastic Leukemia Cells

Jinwei Du, PhD, Shigemi Matsuyama, PhD, Yu-Chung Yang, PhD

Blood (2013) 122 (21): 2913.

https://doi.org/10.1182/blood.V122.21.2913.2913

Published: 2013

Journal Articles

Regulation Of CLL Growth and Trafficking By The Enzymatic Functions Of CD38: Implications For Therapeutic Targeting

Tiziana Vaisitti, PhD, Valentina Audrito, Sara Serra, Giovanna Sociali, Antonella Zucchetto, Erika Tissino, Andrea Pagnani, Candida Vitale, MD, Marta Coscia, MD, PhD, Valter Gattei, Santina Bruzzone, Silvia Deaglio, MD, PhD

Blood (2013) 122 (21): 4112.

https://doi.org/10.1182/blood.V122.21.4112.4112

Published: 2013

Journal Articles

Identification Of Mutations In Bcr-Abl Gene In Newly Diagnosed Indian Patients With Chronic Myelogenous Leukemia (CML)

Aggarwal Shyam, Binuja Verma, Bijal Vyas, Mayank Jauhri

Blood (2013) 122 (21): 5169.

https://doi.org/10.1182/blood.V122.21.5169.5169

Published: 2013

Journal Articles

Alanine Scanning Mutagenesis of the VWF-A1 Flanking Regions of VWF and the Impact on Ristocetin-induced VWF Interaction with Platelets

Robert R. Montgomery, MD, Sandra L. Haberichter, Matt Hille, Patti Morateck, J. Paul Scott, MD, Veronica H. Flood, MD

Blood (2013) 122 (21): 1103.

https://doi.org/10.1182/blood.V122.21.1103.1103

Published: 2013

Journal Articles

Molecular and Functional Characterization of Two Novel Missense Mutations in Iron Transport Protein Causing Hypochromic Microcytic Anemia and Hemosiderosis

Rekha Athiyarath, Neeraj Arora, MD, Rayaz Ahmed, MD, Biju George, MD, Mammen Chandy, MD, Alok Srivastava, MD, Eunice Sindhuvi Edison, Ph.D

Blood (2012) 120 (21): 3202.

https://doi.org/10.1182/blood.V120.21.3202.3202

Published: 2012

Journal Articles

Frequency and Clinical Presentation of Polycomb Repressive Complex 2 (PRC2) Component Mutations in Childhood Acute Lymphoblastic Leukemia

Thomas Ernst, MD, Vivien Schäfer, Jenny Rinke, Anja Waldau, Susan Wittig, Jana Ernst, MD, Ralf Häfer, PhD, James F Beck, MD, Andreas Hochhaus, MD, Bernd Gruhn, MD

Blood (2012) 120 (21): 1474.

https://doi.org/10.1182/blood.V120.21.1474.1474

Published: 2012

Journal Articles

Role of p21 Activated Kinase and Specific Guanine Exchange Factors of Rac Gtpases in Oncogenic KIT Induced Systemic Mastocytosis and Acute Myeloid Leukemia

Holly Martin, Peilin Ma, MD, PhD, Anindya Chatterjee, MS, PhD, Baskar Ramdas, Ph.D., Emily Sims, Cornelis Vlaar, PhD, Suraganie Dharmawardhane, PhD, Reuben Kapur, PhD

Blood (2012) 120 (21): 810.

https://doi.org/10.1182/blood.V120.21.810.810

Published: 2012

Journal Articles

The Bone Marrow Niche of Patients with Acute Lymphoblastic Leukemia Produces No Increased Asparagine Levels In Vivo That May Lead to Clinical Asparaginase Resistance

Wing H. Tong, MD, Rob Pieters, MD, PhD, Wim C.J. Hop, PhD, Claudia Lanvers-Kaminsky, PhD, Joachim Boos, MD, PhD, Inge M. van der Sluis, MD, PhD

Blood (2011) 118 (21): 1505.

https://doi.org/10.1182/blood.V118.21.1505.1505

Published: 2011

Journal Articles

Generation of a FLT3 Kinase Domain Point Mutation (D835Y equivalent) Knock-in Mouse Confers Less Aggressive Disease Compared with FLT3 Internal Tandem Duplication (ITD) Mice

Emily Bailey, DVM, Li Li, PhD, David Huso, D.V.M., Ph.D., Hayley S Wall, Donald Small, MD, PhD

Blood (2011) 118 (21): 924.

https://doi.org/10.1182/blood.V118.21.924.924

Published: 2011

Journal Articles

A Novel Missense Mutation in FGG (c.944C>A) Encodes for An Amino Acid Change (p.Ala315Asp) in the Gamma Chain of Fibrinogen Causing Hypofibrinogenemia and a Thrombotic Phenotype

Larissa Bornikova, MD, Gary Brodsky, PhD, Keith B Neeves, PhD, Rita Marchi, PhD, Donald S Backos, PhD, Philip Reigan, PhD, Alisa S. Wolberg, PhD, Marilyn J. Manco-Johnson, MD, Jorge A Di Paola, MD

Blood (2011) 118 (21): 856.

https://doi.org/10.1182/blood.V118.21.856.856

Published: 2011

Journal Articles

A Novel Missense Mutation Asp69Gly in the Platelet Glycoprotein Ib(beta) Gene in Two Families with Bernard-Soulier Syndrome,

Wolf A Hassenpflug, MD, Belinda Weber, Tobias Obser, Ulrich Budde, MD, Reinhard Schneppenheim, MD, PhD

Blood (2011) 118 (21): 3300.

https://doi.org/10.1182/blood.V118.21.3300.3300

Published: 2011

Journal Articles

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

Peilin Ma, MD, PhD, Raghuveer Mali, Ph.D., Li-Fan Zeng, PhD, Holly Martin, Baskar Ramdas, Ph.D., Yantao He, PhD, Emily Sims, Joydeep Ghosh, Ph.D, Sarah C Nabinger, Shuo Li, Veerendra Munugalavadla, PhD, Anindya Chatterjee, PhD, George Sandusky, MD, Andrew Craig, PhD, Kevin D. Bunting, PhD, Gen-Sheng Feng, Rebecca J. Chan, MD, PhD, Zhong-Yin Zhang, PhD, Reuben Kapur, PhD

Blood (2011) 118 (21): 868.

https://doi.org/10.1182/blood.V118.21.868.868

Published: 2011

NARROW

Higher Order Restrictions of the Immunoglobulin Repertoire in CLL: The Illustrative Case of Stereotyped Subsets #2 and #169

KLF1 Mutations Are Not Common in Israel but Can Explain Occasional Cases of Elevated HbA2 or Very Elevated Fetal Hemoglobin

CLL Stereotyped Subset #4 Igs Acquire Binding to Viable B Lymphocyte Surfaces By Somatic Mutations, Isotype Class Switching, and with the Prerequisite of IG Self-Association

Red Blood Cell-Encapsulation of L-Asparaginase Favorably Modulates Target Selectivity and Pharmacodynamics

Involvement of Allele-Specific Methylation of Asparagine Synthetase Gene in Asparaginase Sensitivity of BCP-ALL

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem Cell Cycling

Casein Kinase 1A1 (CSNK1A1) Is Recurrently Mutated in MDS Patients with Deletion of Chromosome 5q

Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe

CITED2 Facilitates Apoptosis Induced By Histone Deacetylase Inhibitor SAHA In Human Pediatric Pre-B Acute Lymphoblastic Leukemia Cells

Regulation Of CLL Growth and Trafficking By The Enzymatic Functions Of CD38: Implications For Therapeutic Targeting

Identification Of Mutations In Bcr-Abl Gene In Newly Diagnosed Indian Patients With Chronic Myelogenous Leukemia (CML)

Alanine Scanning Mutagenesis of the VWF-A1 Flanking Regions of VWF and the Impact on Ristocetin-induced VWF Interaction with Platelets

Molecular and Functional Characterization of Two Novel Missense Mutations in Iron Transport Protein Causing Hypochromic Microcytic Anemia and Hemosiderosis

Frequency and Clinical Presentation of Polycomb Repressive Complex 2 (PRC2) Component Mutations in Childhood Acute Lymphoblastic Leukemia

Role of p21 Activated Kinase and Specific Guanine Exchange Factors of Rac Gtpases in Oncogenic KIT Induced Systemic Mastocytosis and Acute Myeloid Leukemia

The Bone Marrow Niche of Patients with Acute Lymphoblastic Leukemia Produces No Increased Asparagine Levels In Vivo That May Lead to Clinical Asparaginase Resistance

Generation of a FLT3 Kinase Domain Point Mutation (D835Y equivalent) Knock-in Mouse Confers Less Aggressive Disease Compared with FLT3 Internal Tandem Duplication (ITD) Mice

A Novel Missense Mutation in FGG (c.944C>A) Encodes for An Amino Acid Change (p.Ala315Asp) in the Gamma Chain of Fibrinogen Causing Hypofibrinogenemia and a Thrombotic Phenotype

A Novel Missense Mutation Asp69Gly in the Platelet Glycoprotein Ib(beta) Gene in Two Families with Bernard-Soulier Syndrome,

KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML

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American Society of Hematology

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American Society of Hematology

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