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Journal Articles

Proteomic Profiling of HTLV-1 Carriers and ATL Patients Reveal TNFR2 As a Novel Diagnostic and Chemosensitivity Biomarker for ATL

Carmina Louise Hugo Guerrero, MS, Yoshiko Yamashita, PhD, Megumi Kuba-Miyara, PhD, Naoki Imaizumi, PhD, Shugo Sakihama, PhD, Masaki Hayashi, MD, Takashi Miyagi, MD PhD, Satoko Morishima, MD PhD, Kennosuke Karube, MD PhD, Yuetsu Tanaka, PhD, Hiroaki Masuzaki, MD PhD, Takuya Fukushima, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 660.
https://doi.org/10.1182/blood-2019-129817
Published: 2019
Journal Articles

Decitabine Can Improve the Efficacy of Second-Line Chemotherapy in Relapsed or Refractory Diffuse Llarge B Cell Lymphoma

Xudong Zhang, Junxia Hu, Qingjiang Chen, Mingzhi Zhang, MD PhD, Ken H. Young
Journal: Blood
Blood (2019) 134 (Supplement_1): 5221.
https://doi.org/10.1182/blood-2019-128424
Published: 2019
Journal Articles

CBFA2T3-GLIS2 Fusion Gene Cause Dismal Clinical Course in Acute Megakaryocytic Leukemia of Down Syndrome

Nao Takasugi, Kenichi Amano, Yasuo Kubota, MD, Shota Kato, MD, Yuichi Mitani, MD, Junya Fujimura, MD PhD, Junko Takita, MD PhD, Mitsuteru Hiwatari, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5184.
https://doi.org/10.1182/blood-2019-129165
Published: 2019
Journal Articles

Melatonin Increases the Chemosensitivity of Diffuse Large B Cell Lymphoma Cells to Epirubicin By Inhibiting P-Glycoprotein Expression Via the NF-Κb Pathway

Xiuhua Sun, MD, Hong Qin, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5064.
https://doi.org/10.1182/blood-2019-128271
Published: 2019
Journal Articles

The Genomic and Transcriptomic Landscape of Double-Refractory Multiple Myeloma

Bachisio Ziccheddu, PhD, Giulia Biancon, Chiara De Philippis, MD, Filippo Bagnoli, MD, Francesco Maura, MD, Matteo Dugo, Andrea Devecchi, Loris De Cecco, Marialuisa Sensi, Carolina Terragna, Marina Martello, Tina Bagratuni, PhD, Eftathios Kastritis, Meletios A. Dimopoulos, MD, Michele Cavo, Cristiana Carniti, PhD, Vittorio Montefusco, Paolo Corradini, Niccolo Bolli, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3056.
https://doi.org/10.1182/blood-2019-122197
Published: 2019
Journal Articles

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Amy Abdalla, Nichole Helton, Nathan Salomonis, PhD, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3827.
https://doi.org/10.1182/blood-2019-122967
Published: 2019
Journal Articles

Fludarabine, High Dose Cytarabine and Idarubicin-Based Induction Is Highly Effective in Young AML Patients with Concomitant NPM1 and FLT3-ITD Mutation Irrespectively of FLT3-ITD Allelic Burden

Paola Minetto, MD, Anna Candoni, MD, Fabio Guolo, MD, Marino Clavio, MD, Maria Elena Zannier, MD, Maurizio Miglino, PhD, Maria Vittoria Dubbini, MD, Enrico Carminati, Anna Sicuranza, PhD, Sara Ciofini, Elisabetta Tedone, Nicoletta Colombo, PhD, Girolamo Pugliese, Riccardo Marcolin, MD, Filippo Ballerini, MD, Michele Cea, Marco Gobbi, MD, Monica Bocchia, Renato Fanin, MD, Roberto Massimo Lemoli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3828.
https://doi.org/10.1182/blood-2019-131303
Published: 2019
Journal Articles

Dactinomycin in Acute Myeloid Leukemia with NPM1 Mutations

Guillaume Beziat, Suzanne Tavitian, MD, Sarah Bertoli, MD PhD, Francoise Huguet, MD, Laetitia Largeaud, Francois Vergez, DVM, PhD, Jean-Baptiste Rieu, PharmD, Pierre Bories, MD, Eric Delabesse, MD PhD, Christian Recher, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3900.
https://doi.org/10.1182/blood-2019-125782
Published: 2019
Journal Articles

Isolation and Characterization of a CD34 + Sub-Clone in B-Cell Lymphoma

Ayad Al-Katib, MD, Ebrahim Abdul Shukkur, PhD, Ali M Gabali, MD PhD, ALI Raufi, MD, Salah Ebrahim, MD, Mustapha Kandouz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3970.
https://doi.org/10.1182/blood-2019-130738
Published: 2019
Journal Articles

PKC-Epsilon Overexpression Is Associated with Poor Outcomes in AML and Promotes Chemoresistance and Hematopoietic Stem Cell Quiescence

Rachael Louise Nicholson, BSc, Steven Knapper, DM, Alex Tonks, PhD, Richard L Darley, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2704.
https://doi.org/10.1182/blood-2019-128184
Published: 2019
Journal Articles

The Long Noncoding RNA BALR2 Controls Novel Transcriptional Circuits Involved in Chemotherapy Sensitivity of Pediatric Acute Myeloid Leukemia (AML) Blasts

Valeria Bisio, PhD, Maddalena Benetton, Elena Porcù, PhD, Matteo Bordi, PhD, Carlo Zanon, PhD, Giulia Borella, Ambra Da Ros, Giuseppe Germano, PhD, Sabrina Manni, PhD, Claudia Tregnago, PhD, Silvia Campello, PhD, Dinesh S. Rao, MD PhD, Franco Locatelli, MD PhD, Martina Pigazzi, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2734.
https://doi.org/10.1182/blood-2019-128152
Published: 2019
Journal Articles

Modulation of CD81 By Epigenetic Drug Combination Sensitizes Acute Lymphoblastic Leukemia Via Decreased BTK Signaling

Anthony Quagliano, BS, Anilkumar Gopalakrishnapillai, PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2628.
https://doi.org/10.1182/blood-2019-129198
Published: 2019
Journal Articles

High Throughput Drug Synergy Testing in a Clinical Trial of Panobinostat, Carfilzomib, Dexamethasone to Define Response Biomarkers for Relapsed/Refractory Multiple Myeloma

Pamela S. Becker, MD PhD, Kim Quach, Ted A Gooley, PhD, Edward N. Libby, III, MD, Andrew J. Cowan, MD, David G. Coffey, MD, Bret Gary Degraaff, BS, Cody Hammer, Jin Dai, PhD, Sylvia Chien, Josh Epworth, ARNP, Gabrielle A Zecha, PA-C, Heather Smith, PA-C, Timothy S Martins, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1902.
https://doi.org/10.1182/blood-2019-130990
Published: 2019
Journal Articles

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Johanna D Erbani, Joshua Tay, PhD, Valerie Barbier, Masters, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Ingrid G Winkler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 907.
https://doi.org/10.1182/blood-2019-132233
Published: 2019
Journal Articles

CPX-351 Induces Deep Response and Suppress the Impact of Poor Prognosis Mutations ( TP53, ASXL1, RUNX1 and EVI1 ) Defined By ELN-2017 in t-AML and MRC AML: A Report from a Multicentric French Cohort

Edmond Chiche, Sarah Bertoli, MD PhD, Ramy Rahmé, MD, Jean Baptiste Micol, Florence Pasquier, MD PhD, Pierre Peterlin, Patrice Chevallier, MD, Xavier Thomas, MD PhD, Michael Loschi, MD PhD, Alexis Genthon, Olivier Legrand, MD PhD, Mohamad Mohty, MD PhD, Emmanuel Raffoux, MD, Patrick Auberger, PhD, Alexis Caulier, MD, Magalie Joris, MD, Caroline Bonmati, Gabrielle Roth Guepin, Mathieu Sauvezie, Caroline Lejeune, Arnaud Pigneux, Christian Recher, MD PhD, Lionel Ades, MD PhD, Thomas Cluzeau, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1355.
https://doi.org/10.1182/blood-2019-125623
Published: 2019
Journal Articles

Phase 1 Study of Decitabine and Vorinostat Followed By Fludarabine, Cytarabine and G-CSF (FLAG) in Children, Adolescents and Young Adults with Relapsed/Refractory AML: Report from the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium

Lauren Pommert, MDMS, Deepa Bhojwani, MD, Richard Sposto, PhD, Ellynore Florendo, Eric Schafer, MD, Nathan Gossai, MD, Van Thu Huynh, MD, Sridhar Rao, MD PhD, Michael J. Burke, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1325.
https://doi.org/10.1182/blood-2019-127298
Published: 2019
Journal Articles

Dynamics of Genetic Landscapes and Clonal Evolution between Patients and PDX Models in Acute Myeloid Leukemia

Naomi Kawashima, MD, Yuichi Ishikawa, MD PhD, Akimi Akashi, MS, Hikaru Hattori, MS, Yohei Yamaguchi, MD, Takahiro Nishiyama, MD PhD, Rika Kihara, MD PhD, Yukiyasu Ozawa, Hitoshi Kiyoi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 439.
https://doi.org/10.1182/blood-2018-99-114085
Published: 2018
Journal Articles

Interleukin-2-Inducible T-Cell Kinase (ITK) Inhibitors for the Treatment of T-Cell Lymphoproliferative Disorders

John C. Reneau, MD, Steven R. Hwang, MD, Carlos A. Murga-Zamalloa, MD, Joseph J. Buggy, PhD, James W. Janc, PhD, Ryan A. Wilcox, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4172.
https://doi.org/10.1182/blood-2018-99-110554
Published: 2018
Journal Articles

Whole Genome Bisulfite Sequencing (WGBS) Robustly Measures the Pharmacodynamic Effect of Decitabine/Vorinostat Epigenetic Treatment in Relapsed Pediatric ALL Demonstrating Potent Hypomethylation Associated with Upregulation of PRC2 and TP53 Targets

Rumen Kostadinov, PhD, Byunggil Yoo, MS, Midhat S. Farooqi, MD PhD, Shannon Kelley, MS, Erin Guest, MD, Michael J. Burke, MD, Sarah Wheelan, MD PhD, Patrick Brown, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 918.
https://doi.org/10.1182/blood-2018-99-119206
Published: 2018
Journal Articles

Stemness Signature in AML: GEP with 17 Genes Score Versus Leukemic Stem Cell (LSC) Quantification By Multiparameter Flow Cytometry (MFC)

Adriana Plesa, Christophe Roumier, PharmD, Florent Dumezy, PharmD, Delphine Manzoni, PharmD, Pierre Sujobert, MD PhD, Sandrine Hayette, Isabelle Tigaud, MD, Claude Preudhomme, Karine Celli-Lebras, CRA, Yves Bertrand, MD, Herve Dombret, Xavier Thomas, MD, Meyling Cheok, BSPharm, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4009.
https://doi.org/10.1182/blood-2018-99-119857
Published: 2018