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Journal Articles

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

Claudia Morganti, PhD, Massimo Bonora, PhD, Kyoko Ito, Keisuke Ito, MD PhD

Blood (2019) 134 (Supplement_1): 1188.

https://doi.org/10.1182/blood-2019-125891

Published: 2019

Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Blood (2019) 134 (Supplement_1): 729.

https://doi.org/10.1182/blood-2019-122784

Published: 2019

Journal Articles

The Mitochondrion: A Link Between Hemolysis and Platelet Activation

Sruti Shiva, PhD

Blood (2019) 134 (Supplement_1): SCI-39.

https://doi.org/10.1182/blood-2019-121112

Published: 2019

Journal Articles

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II

Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Rachel Culp-Hill, Julie A. Reisz, Shanshan Pei, Annika Gustafson, Nabilah Khan, James DeGregori, Daniel A. Pollyea, Craig T. Jordan

Blood (2019) 134 (4): 389–394.

https://doi.org/10.1182/blood.2019898114

Published: 2019

Includes: Supplemental data

Journal Articles

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Elena Masselli, MD, Esteban Martinez, BS, Daniela Araiza-Olivera, MD PhD, Giuliana Gobbi, PhD, Prisco Mirandola, PhD, Marco Vitale, MD, Stephen M. Sykes, PhD

Blood (2018) 132 (Supplement 1): 3926.

https://doi.org/10.1182/blood-2018-99-119758

Published: 2018

Journal Articles

Preliminary Results of a Phase 2a Dose Optimization Study of ASLAN003 (DHODH inhibitor) in Acute Myeloid Leukemia (AML) Patients Who Are Ineligible for Standard Therapy; Early Signs of Activity

Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Chin Hin Ng, MD MRCP, Ashish Bajel, MBBS, FRACP, FRCPA, William YK Hwang, MBBS, FRCP(London), MMed(Int MD, FAMS, Shir-Jing Ho, MBBS, FRACP, FRCPA, MClinTrial Res, Wee-Joo Chng, MBBS, PhD FRCPath, FRCP, Mark McHale, B.S., PhD, Chih-Yi Hsieh, MD, Hsuan-Jen Shih, MD, Nicola McIntyre, PhD, Jamie Kwek, Wei-Ling Chang, PhD, Bertil Lindmark, MD PhD

Blood (2018) 132 (Supplement 1): 2676.

https://doi.org/10.1182/blood-2018-99-110570

Published: 2018

Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 910.

https://doi.org/10.1182/blood-2018-99-114525

Published: 2018

Journal Articles

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Yaping Sun, MD PhD MS, Thomas Saunders, PhD, Katherine Oravecz-Wilson, BS, MS, Sydney Bridges, BS, Richard McEachin, PhD, Julia Wu, PhD, Stephanie Kim, Cynthia Zajac, Tomomi Toubai, MDPhD, Hideaki Fujiwara, Israel Henig, MD, Dan Peltier, MD, Pavan Reddy, MD

Blood (2017) 130 (Supplement 1): 2265.

https://doi.org/10.1182/blood.V130.Suppl_1.2265.2265

Published: 2017

Journal Articles

Novel Oxidative Phosphorylation Inhibitor IACS-010759 Induces AMPK-Dependent Apoptosis of AML Cells

Haeun Yang, Yoko Tabe, MD PhD, Kazumasa Sekihara, PhD, Kaori Saito, Helen Ma, MS, Vivian Ruvolo, PhD, Junichi Imoto, Kazuho Ikeo, PhD, Kaoru Mogushi, PhD, Masaki Hosoya, Yoshihide Hayashizaki, MD PhD, Yasunari Yamanaka, MD PhD, Takashi Miida, MD PhD, Michael Andreeff, MD PhD, Joseph R Marszalek, PhD, Marina Konopleva, MD PhD

Blood (2017) 130 (Supplement 1): 1245.

https://doi.org/10.1182/blood.V130.Suppl_1.1245.1245

Published: 2017

Journal Articles

Novel Sites of Gamma Carboxylation in Human Factor VII

Emily M Wilkerson, Barbara Bates, Kraig T Kumfer, Nicholas M Riley, Brad S Schwartz, Joshua J Coon

Blood (2016) 128 (22): 3759.

https://doi.org/10.1182/blood.V128.22.3759.3759

Published: 2016

Journal Articles

Ex Vivo Experiments Show That IDH1/2-Mutant Inhibitors Can be Safely Used As Adjuvants to Regular Chemotherapy in IDH1/2 -Mutated Acute Myeloid Leukemia

Remco Molenaar, M.Sc., Bhumika J. Patel, Mohammed Khurshed, MD, Bartlomiej Przychodzen, MSc, Srinivasa Reddy Sanikommu, MD, Hetty E. Carraway, MD MBA, Tomas Radivoyevitch, PhD, Hideki Makishima, MD PhD, Cornelis J van Noorden, PhD, Jaroslaw P. Maciejewski, MD PhD

Blood (2015) 126 (23): 3788.

https://doi.org/10.1182/blood.V126.23.3788.3788

Published: 2015

Journal Articles

Quantitative Proteomic and Transcriptomic Analysis Reveals Post-Transcriptional Regulation of Mitochondrial Biogenesis during Erythropoiesis

Xin Liu, PhD, Yuannyu Zhang, PhD, Feng Zhou, PhD, Zhen Shao, PhD, Robert Signer, PhD, Hui Cao, M.S., Zeping Hu, PhD, Ralph DeBerardinis, MD PhD, Jian Xu, PhD

Blood (2015) 126 (23): 47.

https://doi.org/10.1182/blood.V126.23.47.47

Published: 2015

Journal Articles

Mitochondrial Activity Determines Hematopoietic Stem Cell Fate Decisions

Nicola Vannini, PhD, Mukul Girotra, Olaia M. Naveiras, MDPhD, Vasco Campos, Evan Williams, Aline Roch, Johan Auwerx, MD PhD, Matthias Lutolf, PhD

Blood (2014) 124 (21): 4327.

https://doi.org/10.1182/blood.V124.21.4327.4327

Published: 2014

Journal Articles

The Dynamic Motion and Delicate Control Of Vkor Catalysis

Weikai Li, PhD

Blood (2013) 122 (21): 2330.

https://doi.org/10.1182/blood.V122.21.2330.2330

Published: 2013

Journal Articles

Cited2 Is Required For The Maintenance Of Glycolytic Metabolism In Adult Hematopoietic Stem Cells

Jinwei Du, PhD, Qiang Li, PhD, Fangqiang Tang, PhD, Michelle Puchowitz, PhD, Hasashi Fujioka, PhD, Sally Dunwoodie, PhD, David Danielpour, PhD, Yu-Chung Yang, PhD

Blood (2013) 122 (21): 794.

https://doi.org/10.1182/blood.V122.21.794.794

Published: 2013

Journal Articles

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

Jhas Bozhena, BSc, Shrivani Sriskanthadevan, PhD, Marko Skrtic, PhD, Mahadeo A. Sukhai, PhD, Veronique Voisin, PhD, Yulia Jitkova, PhD, Marcela Gronda, MSc, Rose Hurren, BSc, Xiaoming Wang, Rob C. Laister, PhD, Gary D. Bader, Ph.D., Mark D. Minden, MD, PhD, Aaron D. Schimmer, MD

Blood (2012) 120 (21): 1364.

https://doi.org/10.1182/blood.V120.21.1364.1364

Published: 2012

Journal Articles

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Shrivani Sriskanthadevan, PhD, Timothy E Chung, Marko Skrtic, PhD, Bozhena Jhas, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Xiao Ming Wang, Yulia Jitkova, PhD, Mahadeo A. Sukhai, PhD, Feng-Hsu Lin, PhD, Neil Maclean, BSc, Rob C. Laister, PhD, Peter Mullen, PhD, Stephanie Xie, Linda Penn, PhD, Ian M. Rogers, PhD, John E. Dick, PhD $, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD

Blood (2012) 120 (21): 2581.

https://doi.org/10.1182/blood.V120.21.2581.2581

Published: 2012

Journal Articles

Mitochondrial Reactive Oxygen Species (ROS) Are Involved in Coated Platelet Formation and Platelet Procoagulant Activity.

Shawn Jobe, MD, PhD, Steven R. Lentz, MD, PhD, Jorge Di Paola, MD

Blood (2005) 106 (11): 3577.

https://doi.org/10.1182/blood.V106.11.3577.3577

Published: 2005

Journal Articles

A Novel Mechanism of Action of Methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate (CDDO-Me): Direct Permeabilization of the Inner Mitochondrial Membrane To Inhibit Electron Transport and Induce Apoptosis.

Ismael Samudio, PhD, Marina Konopleva, MD, PhD, Helene Pelicano, PhD, Peng Huang, MD, PhD, Olga Frolova, PhD, William Bornmann, PhD, Yun-ming Ying, Randall Evans, PhD, Michael Andreeff, MD, PhD

Blood (2005) 106 (11): 4462.

https://doi.org/10.1182/blood.V106.11.4462.4462

Published: 2005

Journal Articles

The Participation of the Hemes of Flavocytochrome b 245 in the Electron Transfer Process in NADPH Oxidase

Andrew Cross

Blood (1999) 93 (12): 4449.

https://doi.org/10.1182/blood.V93.12.4449

Published: 1999

NARROW

Electron Transport Chain Complex II Sustains High Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

The Mitochondrion: A Link Between Hemolysis and Platelet Activation

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II

Pkcε Is a Central Regulator of Mitochondrial Function and Metabolism in Acute Myeloid Leukemia

Preliminary Results of a Phase 2a Dose Optimization Study of ASLAN003 (DHODH inhibitor) in Acute Myeloid Leukemia (AML) Patients Who Are Ineligible for Standard Therapy; Early Signs of Activity

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Novel Oxidative Phosphorylation Inhibitor IACS-010759 Induces AMPK-Dependent Apoptosis of AML Cells

Novel Sites of Gamma Carboxylation in Human Factor VII

Ex Vivo Experiments Show That IDH1/2-Mutant Inhibitors Can be Safely Used As Adjuvants to Regular Chemotherapy in IDH1/2 -Mutated Acute Myeloid Leukemia

Quantitative Proteomic and Transcriptomic Analysis Reveals Post-Transcriptional Regulation of Mitochondrial Biogenesis during Erythropoiesis

Mitochondrial Activity Determines Hematopoietic Stem Cell Fate Decisions

The Dynamic Motion and Delicate Control Of Vkor Catalysis

Cited2 Is Required For The Maintenance Of Glycolytic Metabolism In Adult Hematopoietic Stem Cells

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Mitochondrial Reactive Oxygen Species (ROS) Are Involved in Coated Platelet Formation and Platelet Procoagulant Activity.

A Novel Mechanism of Action of Methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate (CDDO-Me): Direct Permeabilization of the Inner Mitochondrial Membrane To Inhibit Electron Transport and Induce Apoptosis.

The Participation of the Hemes of Flavocytochrome b 245 in the Electron Transfer Process in NADPH Oxidase

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American Society of Hematology

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American Society of Hematology

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