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Journal Articles

The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis

Lauren K. Meyer, Katherine Verbist, PhD, Sabrin Albeituni, PhD, Rachel Bassett, Michelle L. Hermiston, MD PhD, Kim E. Nichols, MD

Blood (2019) 134 (Supplement_1): 81.

https://doi.org/10.1182/blood-2019-129112

Published: 2019

Journal Articles

Potential Role of IL-39 in the Development of Gvhd

David Bastian, Hung Nguyen, PhD, Yongxia Wu, PhD MD, Steven Douglas Schutt, BS, Mohammed Hanief Sofi, PhD MS, Yuejun Liu, PhD, Eric Bartee, PhD, Xue-Zhong Yu, MD MS

Blood (2019) 134 (Supplement_1): 3206.

https://doi.org/10.1182/blood-2019-131251

Published: 2019

Journal Articles

U Distinct Roles of IL-12Rβ1 and IL-23R in the Development of Acute and Chronic Gvhd

David Bastian, Hung D Nguyen, PhD, Yongxia Wu, PhD MD, Steven Douglas Schutt, BS, Anusara Daenthanasanmak, Mohammed Hanief Sofi, PhD MS, Supinya Iamsuwat, Mengmeng Zhang, MD, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 1005.

https://doi.org/10.1182/blood.V130.Suppl_1.1005.1005

Published: 2017

Journal Articles

A Single-Arm PHASE 2A Study of NM-IL-12 (rHu-IL12) in Patients with Mycosis Fungoides-Type CTCL (MF) Undergoing Low-Dose TOTAL Skin Electron BEAM Therapy (LD-TSEBT)

Youn H Kim, MD, Richard T. Hoppe, MD, Alain H Rook, MD, Amit Maity, MD PhD, Larisa J Geskin, MD, David P Horowitz, MD, Genet Finnegan, MHS, PA-C, Michael Khodadoust, MD PhD, Wen-Kai Weng, MD PhD, Analuisa Lares, ANP, BSN, RN, Eric Ki Jun Hong, BS, Marie Buchanan, RN, Vernon Ma, BS, Hue Kha, BS, Chris E Lawrence, PhD, Vladimir Vainstein, MD, Lena A Basile, PhD JD

Blood (2016) 128 (22): 4165.

https://doi.org/10.1182/blood.V128.22.4165.4165

Published: 2016

Journal Articles

Recombinant Human IL-12 Exerts Differential Effects on Circulating CD56 bright and CD56 dim NK Cells in Healthy Human Subjects

Simmy Thomas, PhD, Chris E Lawrence, PhD, Vernon Mar, MS, Hue Kha, MS, Lena A Basile, PhD JD

Blood (2014) 124 (21): 756.

https://doi.org/10.1182/blood.V124.21.756.756

Published: 2014

Journal Articles

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

Vanessa Schneider, Lars Bullinger, MD, PhD, Lu Zhang, Markus Rojewski, Markus Wiesneth, Susanne Hofmann, Marlies Goetz, Hubert Schrezenmeier, MD, Ulla Botzenhardt, Thomas F.E. Barth, Konstanze Doehner, MD, Hartmut Doehner, MD, Jochen Greiner, MD

Blood (2013) 122 (21): 2624.

https://doi.org/10.1182/blood.V122.21.2624.2624

Published: 2013

Journal Articles

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

Nathalie Schmitt, Jacinta Bustamante, Laure Bourdery, Salah Eddine Bentebibel, Stephanie Boisson-Dupuis, Fran Hamlin, Mau V. Tran, Derek Blankenship, Virginia Pascual, Daniel A. Savino, Jacques Banchereau, Jean-Laurent Casanova, Hideki Ueno

Blood (2013) 121 (17): 3375–3385.

https://doi.org/10.1182/blood-2012-08-448902

Published: 2013

Includes: Supplemental data

Journal Articles

Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia

John C. Riches, MD, Ajanthah Sangaralingam, PhD, Shahryar Kiaii, BSc, MSc, PhD, Tracy Chaplin, BSc, Demet Cekdemir, MD, Sameena Iqbal, Alan G. Ramsay, PhD, John G. Gribben, MD, DSc

Blood (2011) 118 (21): 976.

https://doi.org/10.1182/blood.V118.21.976.976

Published: 2011

Journal Articles

IL-12 Enhances Tumor Immunity Via Differential Effects On Regulatory T Cells and Cytotoxic Lymphocytes.

Xuefang Cao, PhD, Karen Leonard, BS

Blood (2009) 114 (22): 1656.

https://doi.org/10.1182/blood.V114.22.1656.1656

Published: 2009

Journal Articles

Reciprocal responsiveness to interleukin-12 and interferon-α specifies human CD8 + effector versus central memory T-cell fates

Hilario J. Ramos, Ann M. Davis, Alexander G. Cole, John D. Schatzle, James Forman, J. David Farrar

Blood (2009) 113 (22): 5516–5525.

https://doi.org/10.1182/blood-2008-11-188458

Published: 2009

Includes: Supplemental data

Journal Articles

IL-12 Stimulates Interferon-Gamma Mediated Inhibition of Tumor-Induced Regulatory T Cell Proliferation and Enhances Tumor Clearance

Xuefang Cao, PhD, Lynne I. Collins, Sheng F. Cai, Joshua C. Mayer, Michael J. Walter, MD, David Piwnica-Worms, MD, PhD, Robert D. Schreiber, PhD, Timothy J. Ley, MD

Blood (2008) 112 (11): 2558.

https://doi.org/10.1182/blood.V112.11.2558.2558

Published: 2008

Journal Articles

Rafting with the IL-12 receptor

Daniel W. McVicar

Blood (2008) 111 (8): 3911–3912.

https://doi.org/10.1182/blood-2008-01-134627

Published: 2008

Journal Articles

Colocalization of the IL-12 receptor and FcγRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-γ

Sri Vidya Kondadasula, Julie M. Roda, Robin Parihar, Jianhua Yu, Amy Lehman, Michael A. Caligiuri, Susheela Tridandapani, Richard W. Burry, William E. Carson, III

Blood (2008) 111 (8): 4173–4183.

https://doi.org/10.1182/blood-2007-01-068908

Published: 2008

Journal Articles

Impaired interferon-γ production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma

Michael J. Robertson, Hua-Chen Chang, David Pelloso, Mark H. Kaplan

Blood (2005) 106 (3): 963–970.

https://doi.org/10.1182/blood-2005-01-0201

Published: 2005

Journal Articles

Interleukin-15 induces IL-12 receptor β1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling

Tipayaratn Musikacharoen, Asako Oguma, Yasunobu Yoshikai, Norika Chiba, Akio Masuda, Tetsuya Matsuguchi

Blood (2005) 105 (2): 711–720.

https://doi.org/10.1182/blood-2004-03-0842

Published: 2005

Journal Articles

Impaired Interferon-Gamma Production as a Consequence of Profound STAT4 Deficiency in Lymphocytes of Lymphoma Patients after Autologous Hematopoietic Stem Cell Transplantation.

Michael J. Robertson, MD, Hua-Chen Chang, David Pelloso, Mark H. Kaplan, PhD

Blood (2004) 104 (11): 448.

https://doi.org/10.1182/blood.V104.11.448.448

Published: 2004

Journal Articles

Naturally occurring anti–IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans

Conny Höflich, Robert Sabat, Simone Rosseau, Bettina Temmesfeld, Hortense Slevogt, Wolf-Dietrich Döcke, Gerald Grütz, Christian Meisel, Elke Halle, Ulf B. Göbel, Hans-Dieter Volk, Norbert Suttorp

Blood (2004) 103 (2): 673–675.

https://doi.org/10.1182/blood-2003-04-1065

Published: 2004

Journal Articles

In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment

Deniz Durali, Marie-Ghislaine de Goër de Herve, Julien Giron-Michel, Bruno Azzarone, Jean-François Delfraissy, Yassine Taoufik

Blood (2003) 102 (12): 4084–4089.

https://doi.org/10.1182/blood-2003-02-0518

Published: 2003

Journal Articles

Missense mutation of the interleukin-12 receptor β1 chain–encoding gene is associated with impaired immunity against Mycobacterium avium complex infection

Tatsunori Sakai, Masao Matsuoka, Manabu Aoki, Kisato Nosaka, Hiroaki Mitsuya

Blood (2001) 97 (9): 2688–2694.

https://doi.org/10.1182/blood.V97.9.2688

Published: 2001

Journal Articles

Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4

Kathy S. Wang, David A. Frank, Jerome Ritz

Blood (2000) 95 (10): 3183–3190.

https://doi.org/10.1182/blood.V95.10.3183

Published: 2000

NARROW

The Combination of Dexamethasone and Ruxolitinib Synergistically Attenuates Disease Manifestations in a Preclinical Model of Hemophagocytic Lymphohistiocytosis

Potential Role of IL-39 in the Development of Gvhd

U Distinct Roles of IL-12Rβ1 and IL-23R in the Development of Acute and Chronic Gvhd

A Single-Arm PHASE 2A Study of NM-IL-12 (rHu-IL12) in Patients with Mycosis Fungoides-Type CTCL (MF) Undergoing Low-Dose TOTAL Skin Electron BEAM Therapy (LD-TSEBT)

Recombinant Human IL-12 Exerts Differential Effects on Circulating CD56 bright and CD56 dim NK Cells in Healthy Human Subjects

Analysis Of Leukemic Stem Cell Population Comparing NPM1 wt and NPM1 mut AML Patients and Potential Therapeutic Targets

IL-12 receptor β1 deficiency alters in vivo T follicular helper cell response in humans

Impact of Lenalidomide on Gene Expression Profiles of Malignant and Immune Cells in Patients with Chronic Lymphocytic Leukemia

IL-12 Enhances Tumor Immunity Via Differential Effects On Regulatory T Cells and Cytotoxic Lymphocytes.

Reciprocal responsiveness to interleukin-12 and interferon-α specifies human CD8 + effector versus central memory T-cell fates

IL-12 Stimulates Interferon-Gamma Mediated Inhibition of Tumor-Induced Regulatory T Cell Proliferation and Enhances Tumor Clearance

Rafting with the IL-12 receptor

Colocalization of the IL-12 receptor and FcγRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-γ

Impaired interferon-γ production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma

Interleukin-15 induces IL-12 receptor β1 gene expression through PU.1 and IRF 3 by targeting chromatin remodeling

Impaired Interferon-Gamma Production as a Consequence of Profound STAT4 Deficiency in Lymphocytes of Lymphoma Patients after Autologous Hematopoietic Stem Cell Transplantation.

Naturally occurring anti–IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans

In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment

Missense mutation of the interleukin-12 receptor β1 chain–encoding gene is associated with impaired immunity against Mycobacterium avium complex infection

Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4

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American Society of Hematology

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American Society of Hematology

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