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Journal Articles

PML Plays a Key Role in Severe Congenital Neutropenia with Mutant ELANE Causing Neutrophil Elastase Protein Misfolding

Patricia Olofsen, MSc, Paulette van Strien, BSc, Onno Roovers, BSc, Hans De Looper, BSc, Remco Hoogenboezem, MSc, Dennis Bosch, BSc, Mehrnaz Ghazvini, PhD, Eric Bindels, PhD, Emma De Pater, PhD, Ivo Touw, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 213.
https://doi.org/10.1182/blood-2019-122423
Published: 2019
Journal Articles

Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia

César Alexander Ortiz Rojas, BSc, Diego A Pereira-Martins, MSc, Isabel Weinhäuser, MSc, Luciana Yamamoto Almeida, PhD, Thiago Mantello Bianco, MSc, Lorena Lobo Figueiredo-Pontes, MD PhD, Luisa C A Koury, MD, Raul Antônio Morais Melo, MD PhD, Rosane Bittencourt, Katia B Pagnano, MD PhD, Ricardo Pasquini, MD, Elenaide C. Nunes, MD, Evandro Maranhão Fagundes, MD, Ana Beatriz F. Gloria, MD, Fabio R. Kerbauy, MD, Armand Keating, MD, Martin S. Tallman, MD, Raul Ribeiro, MD, Richard Dillon, MA, PhD MRCP, FRCPath, Arnold Ganser, MD, Bob Löwenberg, MD PhD, Peter Valk, PhD, Miguel A. Sanz, Nancy Berliner, MD, Eduardo M Rego, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2719.
https://doi.org/10.1182/blood-2019-131211
Published: 2019
Journal Articles

PML Mutation in PML-Rarα Alters PML Nuclear Body Organization and Induces ATRA Resistance in Acute Promyelocytic Leukemia

Hong-Hu Zhu, MD, Congying Wu, Yujie Sun, Jiong Hu, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3923.
https://doi.org/10.1182/blood-2018-99-118310
Published: 2018
Journal Articles

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

Zuzana Tothova, MD PhD, John M. Krill-Burger, MS, Daniel S. Day, PhD, J. Erika Haydu, MD PhD, Brian J. Abraham, PhD, Catherine C. Landers, BA, Edyta Malolepsza, PhD, Christina R. Hartigan, BS, Amie Holmes, PhD, Melanie Donahue, BS, Katerina D. Popova, BA, Sebastian Koochaki, MS, Jeanne Rivera, BSc, Michael Seiler, PhD, Denes Hnisz, PhD, Edwin Chen, PhD, Silvia Buonamici, PhD, Monica Schenone, PhD, Alan D. D'Andrea, MD, Steven A. Carr, PhD, Richard A. Young, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 940.
https://doi.org/10.1182/blood-2018-99-117480
Published: 2018
Journal Articles

Pml Nuclear Body Disruption Cooperates in APL Pathogenesis, Impacting DNA Damage Repair Pathways

Edwige Voisset, PhD, Eva Moravcsik, Eva W Stratford, Amie Jaye, Christopher J Palgrave, Robert K Hills, DPhil, Paolo Salomoni, Scott C. Kogan, MD, Ellen Solomon, David Grimwade, PhD FRCPath
Journal: Blood
Blood (2016) 128 (22): 742.
https://doi.org/10.1182/blood.V128.22.742.742
Published: 2016
Journal Articles

The Long Non-Coding RNA NEAT1 Modulates Imatinib-Induced Apoptosis in CML Cells

Chengwu Zeng, Sichu Liu, Lijian Yang, Shaohua Chen, Yangqiu Li
Journal: Blood
Blood (2015) 126 (23): 4019.
https://doi.org/10.1182/blood.V126.23.4019.4019
Published: 2015
Journal Articles

Characterizing the Inflammasome in Polycythemia Vera

Susan C Rhodes, MBChB, Rafaella Gavriilidou, Mark W. Drummond, PhDMD, Mhairi Copland, BSc (Hons) MB ChB PhDFRCP FRCPath, Helen Wheadon
Journal: Blood
Blood (2015) 126 (23): 2827.
https://doi.org/10.1182/blood.V126.23.2827.2827
Published: 2015
Journal Articles

The IRF2BP2-RARα Fusion Generated By a Cryptic Rearrangement Transforms Hematopoietic Stem/Progenitor Cells and Induces Retinoid Sensitive Acute Promyelocytic Leukemia (APL)

Jelena V Jovanovic, M Carmen Chillón, Christelle Vincent-Fabert, Richard Dillon, Edwige Voisset, Norma C Gutiérrez, Ellen Solomon, Ramón Garcí­a Sanz, Ana A. Martin Lopez, Yvonne G Morgan, Jennie Lok, Estelle Duprez, PhD, Marcos González Díaz, David Grimwade
Journal: Blood
Blood (2014) 124 (21): 2325.
https://doi.org/10.1182/blood.V124.21.2325.2325
Published: 2014
Journal Articles

In Vivo Analysis of PML-RARA in a Humanized Mouse Model

Hiromichi Matsushita, MD PhD, Takashi Yahata, PhD, Yin Sheng, PhD, Yoshihiko Nakamura, PhD, Yukari Muguruma, PhD, Hideyuki Matsuzawa, Masayuki Tanaka, Hideki Hayashi, Tadayuki Sato, Anar Damdinsuren, MD, Makoto Onizuka, MD PhD, Mamoru Ito, Hayato Miyachi, MD PhD, Pier Paolo Pandolfi, MD PhD, Kiyoshi Ando
Journal: Blood
Blood (2014) 124 (21): 1020.
https://doi.org/10.1182/blood.V124.21.1020.1020
Published: 2014
Journal Articles

Proteasome Activity Is Dispensable for the Degradation of PML-RARα: Efficacy of Bortezomib Along with Arsenic Trioxide in the Treatment of Arsenic Sensitive and Resistant Acute Promyelocytic Leukemia

Saravanan Ganesan, MSc, Ansu Abu Alex, MSc, Ezhilarasi Chendamarai, PhD, Nithya Balasundaram, MSc, Hamenth Kumar Palani, MSc, Sachin David, MSc, Jayandharan G Rao, PhD, Aby Abraham, MD, Auro Viswabandya, MD, Biju George, MD, Alok Srivastava, MD, Poonkuzhali Balasubramanian, PhD, Rose Ann Padua, PhD, Christine Chomienne, MD PhD, Vikram Mathews, MD
Journal: Blood
Blood (2014) 124 (21): 3741.
https://doi.org/10.1182/blood.V124.21.3741.3741
Published: 2014
Journal Articles

Cyclin D1 Maintains Mantle Cell Lymphoma Through CDK4-Independent Regulation Of DNA Replicative Checkpoints

Suchismita Mohanty, PhD, Atish Mohanty, PhD, Natalie Sandoval, MS, Victoria Bedell, Joyce Murata-Collins, PhD, Jun Wu, PhD, Anna Scuto, Dennis D. Weisenburger, MD, Vu N Ngo, PhD
Journal: Blood
Blood (2013) 122 (21): 2512.
https://doi.org/10.1182/blood.V122.21.2512.2512
Published: 2013
Journal Articles

Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

Eva Moravcsik, Melanie Joannides, Edwige Voisset, Eva Wessel Stratford, Bernd B. Zeisig, Jo Morris, Ruth Densham, Chris Palgrave, Gordon Stamp, Emma Nye, Robert K. Hills, Paolo Salomoni, Chi Wai Eric So, PHD, Scott C. Kogan, Ellen Solomon, David Grimwade, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3721.
https://doi.org/10.1182/blood.V122.21.3721.3721
Published: 2013
Journal Articles

Specific PML Isoforms and SATB1 Affect HLA Expression In Classical Hodgkin Lymphoma

Yuxuan Liu, Anke Van Den Berg, PhD, Bea Rutgers, Rianne Veenstra, Debora de Jong, Gertrud Kortman, Gustaaf van Imhoff, Lydia Visser, Arjan Diepstra, MD PhD
Journal: Blood
Blood (2013) 122 (21): 4234.
https://doi.org/10.1182/blood.V122.21.4234.4234
Published: 2013
Journal Articles

Transcriptional Repression Of CDKN2D by PML/RARα Contributes To The Altered Proliferation and Differentiation Block Of Acute Promyelocytic Leukemia Cells

Xiaohong Jia, Yun Tan, Yewei Wang, Xuehua Zhu, Xianwen Yang, Wen Jin, Ji Zhang, Kankan Wang
Journal: Blood
Blood (2013) 122 (21): 3743.
https://doi.org/10.1182/blood.V122.21.3743.3743
Published: 2013
Journal Articles

The Acute Promyelocytic Leukemia-Oncoprotein PML-Raralpha Blocks Senescence and Disrupts The Atrx/Daxx Chromatin Remodeling Complex To Promote Leukemia

Katharina Korf, Harald Wodrich, Alexander Haschke, Ron M. Evans, PhD, Thomas M. Sternsdorf, PhD.
Journal: Blood
Blood (2013) 122 (21): 1267.
https://doi.org/10.1182/blood.V122.21.1267.1267
Published: 2013
Journal Articles

Strong HLA Class I Expression Is Positively Correlated with the Number of PML Nuclear Bodies and Negatively with the Percentage of SATB1 Positive HRS Cells in EBV+ Classical Hodgkin Lymphoma (cHL)

Yuxuan Liu, Lydia Visser, Rianne Veenstra, Bea Rutgers, Anke Van Den Berg, PhD, Arjan Diepstra, MD PhD
Journal: Blood
Blood (2012) 120 (21): 3633.
https://doi.org/10.1182/blood.V120.21.3633.3633
Published: 2012
Journal Articles

The Functional Link Between CDK1 and Retinoic Acid Receptor γ (RARγ) in Response to Treatment with All-Trans Retinoic Acid

Andreas Hedblom, Kristian B Laursen, PhD, Regina R Miftakhova, Martuza Sarwar, Nigel P Mongan, PhD, Lorraine J Gudas, PhD, Jenny L Persson, PhD
Journal: Blood
Blood (2011) 118 (21): 2485.
https://doi.org/10.1182/blood.V118.21.2485.2485
Published: 2011
Journal Articles

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

Youmna Kfoury, Niclas Setterblad, Marwan El-Sabban, Alessia Zamborlini, Zeina Dassouki, Hiba El Hajj, Olivier Hermine, Claudine Pique, Hugues de Thé, Ali Saïb, Ali Bazarbachi
Journal: Blood
Blood (2011) 117 (1): 190–199.
https://doi.org/10.1182/blood-2010-05-285742
Published: 2011
Includes: Supplemental data
Journal Articles

Association of PML Expression with Chemotherapy-Resistance In Multiple Myeloma Cells

Daisuke Ohgiya, MD, Makoto Onizuka, MD, PhD, Hiromichi Matsushita, MD, PhD, Naoya Nakamura, MD, PhD, Hiroshi Kawada, MD, PhD, Yoshiaki Ogawa, MD, PhD, Kiyoshi Ando, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2959.
https://doi.org/10.1182/blood.V116.21.2959.2959
Published: 2010
Journal Articles

Study on the Role of PML on Cell Proliferation and Differentiation In Human Mesenchymal Stem Cells

Jie Sun, He Huang, MD, PhD, Weijun Zhong, Shan Fu
Journal: Blood
Blood (2010) 116 (21): 4711.
https://doi.org/10.1182/blood.V116.21.4711.4711
Published: 2010