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Journal Articles

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

Michael W. Henderson, Erica M. Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F. Noubouossie, Reiner Mailer, Thomas Renné, Matthew J. Flick, James P. Luyendyk, Zu-Lin Chen, Sidney Strickland, R. Todd Stravitz, Keith R. McCrae, Nigel S. Key, Rafal Pawlinski

Blood (2021) 138 (3): 259–272.

https://doi.org/10.1182/blood.2020006198

Published: 2021

Includes: Supplemental data

Journal Articles

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Michael Wayne Henderson, MSc, Erica Sparkenbaugh, PhD BS, Denis Noubouossie, MD PhD, Reiner Mailer, Thomas Renne, MD PhD, Keith R McCrae, MD, Nigel S. Key, MBChB, FRCP, Rafal Pawlinski, PhD

Blood (2019) 134 (Supplement_1): 3621.

https://doi.org/10.1182/blood-2019-127206

Published: 2019

Journal Articles

Heavy chain of FXII: not an innocent bystander!

Helen Philippou

Blood (2019) 133 (10): 1008–1009.

https://doi.org/10.1182/blood-2019-01-895110

Published: 2019

Journal Articles

Exosome Polyphosphate Mediates the Activation of FXII By Cancer Cell-Derived Exosomes

Dewen You, PhD, Suman Kundu, MBA, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith R. McCrae, MD

Blood (2018) 132 (Supplement 1): 3800.

https://doi.org/10.1182/blood-2018-99-117308

Published: 2018

Journal Articles

Detection and Differential Diagnosis of Prekallikrein Deficiency: Genetic Study of New Families and Systematic Review of the Literature

Stefano Barco, Stefanie Sollfrank, Alice Trinchero, Luigi Tomao, Barbara Zieger, Johanna A. Kremer Hovinga, MD Prof, Laura Conti, Anke Adenäuer, Erwin Miloni, Karl J. Lackner, Heidi Rossmann, Bernhard Lammle, MD

Blood (2018) 132 (Supplement 1): 2496.

https://doi.org/10.1182/blood-2018-99-116030

Published: 2018

Journal Articles

High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

Erica Sparkenbaugh, PhD BS, Kathryn Wilson, BS, Malgorzata Kasztan, PhD, David M. Pollock, PhD, Keith R. McCrae, MD, Rafal Pawlinski, PhD

Blood (2018) 132 (Supplement 1): 268.

https://doi.org/10.1182/blood-2018-99-116526

Published: 2018

Journal Articles

Coagulation Factor XII Plays an Important Role in Procoagulant Activity of Apoptotic Cells

Aizhen Yang, Yi Wu, MD PhD

Blood (2018) 132 (Supplement 1): 2457.

https://doi.org/10.1182/blood-2018-99-118223

Published: 2018

Journal Articles

A Novel Immunoblot Assay to Detect Contact Activation in Patients with Cancer

Dewen You, PhD, Victor Chatterjee, MD, Mohamed Samour, MBBS, Suman Kundu, MBA, Alvin H. Schmaier, MD, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2385.

https://doi.org/10.1182/blood.V130.Suppl_1.2385.2385

Published: 2017

Journal Articles

High Molecular Weight Kininogen Alters the Tumor Microenvironment and Reduces Tumor Stem Cell Content

Meenal Shukla, James Hale, PhD, Justin Lathia, PhD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2340.

https://doi.org/10.1182/blood.V130.Suppl_1.2340.2340

Published: 2017

Journal Articles

Cancer Cell-Derived Extracellular Vesicles Are Prothrombotic in an in-Vitro Vessel Model

Victor Chatterjee, MD, Mohamed Samour, MBBS, Dewen You, PhD, Suman Kundu, MBA, Alok A. Khorana, MD, Keith McCrae, MD

Blood (2017) 130 (Supplement 1): 2308.

https://doi.org/10.1182/blood.V130.Suppl_1.2308.2308

Published: 2017

Journal Articles

Regulation of the Tumor Microenvironment By High Molecular Weight Kininogen

Meenal Shukla, PhD, Venkaiah Betapudi, PhD, Ravi Kumar Alluri, PhD, Sergei Merkulov, PhD, James Hale, PhD, Justin Lathia, PhD, Keith R. McCrae, MD

Blood (2016) 128 (22): 1394.

https://doi.org/10.1182/blood.V128.22.1394.1394

Published: 2016

Journal Articles

High Prevalence of Marginal ZONE Lymphoma Among Patients with Acquired C1- Inhibtor Deficiency

Roberto Castelli, Prof, Davide Rossi, MD PhD, Arquati Massimo, Suffritti Chiara, Andrea Zanichelli, Wu Maddalena, Cicardi Marco, Prof

Blood (2015) 126 (23): 1444.

https://doi.org/10.1182/blood.V126.23.1444.1444

Published: 2015

Journal Articles

Purified DNA, but Not Neutrophil Extracellular Traps (NETs), Promotes Contact Activation of Coagulation

Denis Noubouossie, MD PhD, Matthew F Whelihan, PhD, Dougald M. Monroe, III, PhD, Nigel S. Key, MB, ChB

Blood (2015) 126 (23): 767.

https://doi.org/10.1182/blood.V126.23.767.767

Published: 2015

Journal Articles

The polyphosphate–factor XII pathway drives coagulation in prostate cancer-associated thrombosis

Katrin F. Nickel, Göran Ronquist, Florian Langer, Linda Labberton, Tobias A. Fuchs, Carsten Bokemeyer, Guido Sauter, Markus Graefen, Nigel Mackman, Evi X. Stavrou, Gunnar Ronquist, Thomas Renné

Blood (2015) 126 (11): 1379–1389.

https://doi.org/10.1182/blood-2015-01-622811

Published: 2015

Includes: Supplemental data

Journal Articles

The SRC Kinase Family Member Lymphocyte Specific Kinase (p56 Lck ) Regulates Endothelial Cell Proliferation and Survival

Venkaiah Betapudi, PhD, Sergei M. Merkoulov, PhD, Suman Kundu, MBA, Ou Ji, MD, Meifang Wu, MD, Keith R. McCrae, MD

Blood (2014) 124 (21): 1445.

https://doi.org/10.1182/blood.V124.21.1445.1445

Published: 2014

Journal Articles

Prolylcarboxypeptidase Is a Risk Factor for Cardiovascular Events

Alvin H. Schmaier, MD, Alona Merkulova, MS, Haley Gittleman, BA, Omar Alhalabi, MD, Evi Stavrou, MD, Martina Veigl, PhD, Jill Barnholtz-Sloan, PhD

Blood (2014) 124 (21): 1531.

https://doi.org/10.1182/blood.V124.21.1531.1531

Published: 2014

Journal Articles

A Biomarker Assay For The Detection Of Contact System Activation

Ryan R Faucette, Marco Cicardi, MD, Chiara Suffritti, PhD, Jon A Kenniston, Daniel J Sexton, Burt Adelman

Blood (2013) 122 (21): 2347.

https://doi.org/10.1182/blood.V122.21.2347.2347

Published: 2013

Journal Articles

Comparison Of Plasma Kallikrein Inhibition By The Endogenous C1-Inhibitor Versus DX-2930, a Monoclonal Antibody Inhibitor

Daniel J Sexton, Jon A Kenniston, Ryan R Faucette, Andrew E Nixon, Chris TenHoor, Yung Chyung, Burt Adelman

Blood (2013) 122 (21): 1066.

https://doi.org/10.1182/blood.V122.21.1066.1066

Published: 2013

Journal Articles

Thrombosis Protection In Klkb1 -/- (Prekallikrein KO) Mice Is Mediated By Increased Renal Mas Receptor, Plasma Prostacyclin, and Aortic Sirt1

Chao Fang, Evi Stavrou, MD, Yunmei Wang, PhD, Nadja Grobe, PhD, Daniel I. Simon, MD, Alvin H. Schmaier, MD

Blood (2013) 122 (21): 195.

https://doi.org/10.1182/blood.V122.21.195.195

Published: 2013

NARROW

Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure

High Molecular Weight Kininogen but Not Factor XII Deficiency Attenuates Acetaminophen-Induced Liver Injury in Mice

Heavy chain of FXII: not an innocent bystander!

Exosome Polyphosphate Mediates the Activation of FXII By Cancer Cell-Derived Exosomes

Detection and Differential Diagnosis of Prekallikrein Deficiency: Genetic Study of New Families and Systematic Review of the Literature

High Molecular Weight Kininogen Contributes to End-Organ Damage and Mortality in a Mouse Model of Sickle Cell Disease

Coagulation Factor XII Plays an Important Role in Procoagulant Activity of Apoptotic Cells

A Novel Immunoblot Assay to Detect Contact Activation in Patients with Cancer

High Molecular Weight Kininogen Alters the Tumor Microenvironment and Reduces Tumor Stem Cell Content

Cancer Cell-Derived Extracellular Vesicles Are Prothrombotic in an in-Vitro Vessel Model

Regulation of the Tumor Microenvironment By High Molecular Weight Kininogen

High Prevalence of Marginal ZONE Lymphoma Among Patients with Acquired C1- Inhibtor Deficiency

Purified DNA, but Not Neutrophil Extracellular Traps (NETs), Promotes Contact Activation of Coagulation

The polyphosphate–factor XII pathway drives coagulation in prostate cancer-associated thrombosis

The SRC Kinase Family Member Lymphocyte Specific Kinase (p56 Lck ) Regulates Endothelial Cell Proliferation and Survival

Prolylcarboxypeptidase Is a Risk Factor for Cardiovascular Events

A Biomarker Assay For The Detection Of Contact System Activation

Comparison Of Plasma Kallikrein Inhibition By The Endogenous C1-Inhibitor Versus DX-2930, a Monoclonal Antibody Inhibitor

Discovery and Characterization Of a Highly Specific Antibody Inhibitor Of Plasma Kallikrein

Thrombosis Protection In Klkb1 -/- (Prekallikrein KO) Mice Is Mediated By Increased Renal Mas Receptor, Plasma Prostacyclin, and Aortic Sirt1

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American Society of Hematology

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American Society of Hematology

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