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Journal Articles

Targeting WNT10B-Driven Signalling through Induction of FZD6 By Porcupine Inhibition in T Cell Acute Lymphoblastic Leukemia

Adriana Cassaro, PhD, Francesca Lazzaroni, Dr, Giovanni Grillo, MD, Gianluigi Reda, MD, Roberto Cairoli, MD, Alessandro Beghini

Blood (2019) 134 (Supplement_1): 3956.

https://doi.org/10.1182/blood-2019-124871

Published: 2019

Journal Articles

MYD88 Triggered SYK Activation Promotes BCR Cross-Talk, and Identifies SYK As a Novel Therapeutic Target of Mutated MYD88 Signaling

Manit Munshi, MS, Jiaji Chen, BS, Xia Liu, MD, Lian Xu, MS, Nickolas Tsakmaklis, BA, Maria Demos, Amanda Kofides, Maria Luisa Guerrera, MD, Gloria G Chan, MS, Christopher Patterson, MAcc, Kirsten Meid, MPH, Joshua Gustine, MPH, Jorge J. Castillo, MD, Zachary R Hunter, PhD, Jinhua Wang, PhD, Sara J Buhrlage, PhD, Nathanael S. Gray, PhD, Steven P Treon, MD PhD FRCP, Guang Yang, PhD

Blood (2018) 132 (Supplement 1): 4116.

https://doi.org/10.1182/blood-2018-99-117372

Published: 2018

Journal Articles

The Role of Cbx Proteins in Human Benign and Malignant Hematopoiesis

Johannes Jung, MD, Hein Schepers, PhD, Seka Lazare, Sonja Buisman, Ellen Weersing, Bertien Dethmers, Karin Klauke, PhD, Lenja Bystrykh, PhD, Gerald De Haan, PhD

Blood (2016) 128 (22): 2651.

https://doi.org/10.1182/blood.V128.22.2651.2651

Published: 2016

Journal Articles

NR4A3 Suppresses Lymphomagenesis I n Vitro and In Vivo by Induction of Similar Patterns of Pro-Apoptotic Genes like NR4A1

Alexander JA Deutsch, PhD, Beate Rinner, Martin Pichler, Karoline Fechter, Hildegard T. Greinix, MD, Chenguang Wang, Christine Beham-Schmid, MD, Peter Neumeister, MD

Blood (2016) 128 (22): 2728.

https://doi.org/10.1182/blood.V128.22.2728.2728

Published: 2016

Journal Articles

Genetic Depletion of Fc Gamma Receptor 2b Affects CML Stem Cell Biology

Oliver Herrmann, MSc, Caroline CA Weßling, MD, Michael Huber, PhD, Shaoguang Li, MD PhD, Tim H. Brümmendorf, MD, Steffen Koschmieder, MD, Mirle Schemionek, PhD

Blood (2014) 124 (21): 4528.

https://doi.org/10.1182/blood.V124.21.4528.4528

Published: 2014

Journal Articles

Identification of CAR As a Novel Mediator of Erythroid Differentiation and Migration That Is Specifically Downregulated in Erythropoietic Progenitor Cells in Patients with MDS

Karin Bauer, PhD, Sigrid Machherndl-Spandl, MD, Susanne Suessner, MSc, Martin Danzer, MSc, Johannes Pröll, PhD, Jeroen Lauf, Gregor Eisenwort, MD PhD, Wolfgang R. Sperr, MD, Hans-Ulrich Klein, PhD, Gregor Hoermann, MD PhD, Norman Häfner, PhD, Marie Bene, PharmSciD, PhD, Uwe Platzbecker, MD, Ansgar Weltermann, MD, Christian Gabriel, MD, Ulrich Germing, Peter Bettelheim, MD, Peter Valent, MD

Blood (2014) 124 (21): 1570.

https://doi.org/10.1182/blood.V124.21.1570.1570

Published: 2014

Journal Articles

Peroxiredoxin 6 (Prdx6) Is Associated with Changes in Autophagy in Myeloid and Non-Myeloid Cells

Michael Ellison, PhD, Gail Thurman, BA, Daniel R. Ambruso, MD

Blood (2014) 124 (21): 1407.

https://doi.org/10.1182/blood.V124.21.1407.1407

Published: 2014

Journal Articles

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression

Valeria Cazzaniga, Marco Giordan, Cristina Bugarin, Chiara Palmi, Angela Savino, Geertruy te Kronnie, Giuseppe Gaipa, Andrea Biondi, Grazia Fazio, PhD, Giovanni Cazzaniga, PhD

Blood (2013) 122 (21): 3738.

https://doi.org/10.1182/blood.V122.21.3738.3738

Published: 2013

Journal Articles

RUNX1a Enhances Hematopoietic Lineage Commitment From Human Embryonic Stem Cells and Inducible Pluripotent Stem Cells

Dan Ran, MD, PhD, Wei-Jong Shia, PhD, Miao-Chia Lo, PhD, Junbao Fan, Ph.D, David A. Knorr, BSc, Patrick I Ferrell, B.S., Zhaohui Ye, PhD, Ming Yan, PhD, Linzhao Cheng, PhD, Dan S. Kaufman, MD, PhD, Dong-Er Zhang, PhD

Blood (2012) 120 (21): 347.

https://doi.org/10.1182/blood.V120.21.347.347

Published: 2012

Journal Articles

Apoptosis Repressor with Caspase Recruitment Domain Is Regulated by the cIAP1-NIK Axis and Confers Resistance to SMAC Mimetic Birinapant-Induced Cell Death in AML

Bing Z. Carter, Ph.D, Po Yee Mak, M.S., Duncan H. Mak, M.S., Vivian Ruvolo, Rodrigo Jacamo, Ph.D, Steven M. Kornblau, MD, PhD, Michael Andreeff, MD, PhD

Blood (2012) 120 (21): 534.

https://doi.org/10.1182/blood.V120.21.534.534

Published: 2012

Journal Articles

Mutant U2AF1(S34F) Expression Alters Hematopoiesis in Mice

Cara L Lunn, Ph.D., Justin Tibbitts, MS MBA, James N Ley, Jin Shao, Timothy Graubert, MD, Matthew J. Walter, MD

Blood (2012) 120 (21): 553.

https://doi.org/10.1182/blood.V120.21.553.553

Published: 2012

Journal Articles

Regulation of Fas-mediated Apoptosis in B-Cell Lymphomas by Nucleolin.

Felipe Samaniego, MD, MPH, Jillian F Wise, BS, Rong-Hua Tao, MD, PhD, Haifeng Zhu, PhD, Xue Ao, MS, Zeming Chen, PhD, Wenzhuo Zhuang, PhD, Frank K Braun, PhD, Rohit Mathur, PhD, Jorge Enrique Romaguera, MD, Luis Fayad, MD, Michael Wang, MD, Peter McLaughlin, MD, Timothy J. McDonnell, MD, PhD, Keyur P. Patel, MD, PhD, Sattva S. Neelapu, MD, Larry W. Kwak, MD, PhD, Zuzana Berkova, PhD

Blood (2012) 120 (21): 2406.

https://doi.org/10.1182/blood.V120.21.2406.2406

Published: 2012

Journal Articles

Dysregulation of GPR34 in Indolent Lymphomas and Its Function As a Novel Regulator of Cell Growth and Gene Expression

Anne J. Novak, Ph.D., Takashi Akasaka, MD, PhD, Michelle K Manske, Esteban Braggio, PhD, Tammy Price-Troska, Steve Ziesmer, Secreto Frank, Ph.D., Rafael Fonseca, MD, Mamta Gupta, PhD, Mark E Law, Thomas E. Witzig, MD, Martin JS Dyer, MA, DPhil, FRCP, FRCPath, Ahmet Dogan, Ellen McPhail, MD, James R Cerhan, MD, PhD, Stephen Ansell

Blood (2011) 118 (21): 1570.

https://doi.org/10.1182/blood.V118.21.1570.1570

Published: 2011

Journal Articles

GATA1s Exerts Fetal Stage-Specific Oncogenic Effects in Human Hematopoietic Stem and Progenitor Cells

Aliaksandra Maroz, Ben Van Handel, Hanna Mikkola, MD, PhD, Jennifer Schoenning, Dirk Reinhardt, MD, PhD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 2355.

https://doi.org/10.1182/blood.V118.21.2355.2355

Published: 2011

Journal Articles

Impaired Reconstitution Potential of TGFβ-Hypersensitive Human Hematopoietic Stem Cells

Emma Rörby, Matilda Nifelt Hägerström, Ulrika Blank, Göran Karlsson, Ph.D., Stefan Karlsson, M.D., Ph.D., Prof.

Blood (2011) 118 (21): 394.

https://doi.org/10.1182/blood.V118.21.394.394

Published: 2011

Journal Articles

A Novel Ubiquitination Pathway Regulates MLL Activity During Hematopoietic Differentiation

Jingya Wang, Ph.D., Andrew G. Muntean, PhD, Jay L. Hess, MD, PhD

Blood (2010) 116 (21): 743.

https://doi.org/10.1182/blood.V116.21.743.743

Published: 2010

Journal Articles

SYK Is a Tumor Suppressor In Pre-B Cell Acute Lymphoblastic Leukemia and Not a Therapeutic Target

Carina Ng, Rahul Nahar, Emily Elliott, Clifford A. Lowell, Markus Muschen

Blood (2010) 116 (21): 4199.

https://doi.org/10.1182/blood.V116.21.4199.4199

Published: 2010

Journal Articles

SMAC-Mimetic BV-6 Sensitizes Therapeutic Agents-Induced Apoptosis In AML Cells

Duncan H Mak, M.S., Christa Manton, Michael Andreeff, MD, PhD, Bing Z Carter, Ph.D.

Blood (2010) 116 (21): 2177.

https://doi.org/10.1182/blood.V116.21.2177.2177

Published: 2010

Journal Articles

Group A Pak Proteins Are Essential for HSC/P Engraftment.

Adrienne M. Dorrance, PhD, Abel Sanchez-Aguilera, PhD, Serena De Vita, MD, PhD, Michael D. Milsom, PhD, Jonathan Chernoff, MD, PhD, David A. Williams, MD

Blood (2010) 116 (21): 2624.

https://doi.org/10.1182/blood.V116.21.2624.2624

Published: 2010

Journal Articles

PAX5/TEL Exhibits a Dominant-Negative Role by Inhibiting the Expression of Genes Involved in BCR Signalling and Suppressing the Binding of Wild Type PAX5 to Its Direct Target Gene CD79A (mb-1) in a human Pre-B ALL Cell Line.

Gabriela B. Iwanski, MD, Nils Heinrich Thoennissen, MD, PohYeen Lor, Norihiko Kawamata, MD, PhD, Daniel Nowak, MD, Grazia Fazio, PhD, Andrea Biondi, MD, Giovanni Gazzaniga, PhD, H. Phillip Koeffler, MD

Blood (2009) 114 (22): 3455.

https://doi.org/10.1182/blood.V114.22.3455.3455

Published: 2009

NARROW

Targeting WNT10B-Driven Signalling through Induction of FZD6 By Porcupine Inhibition in T Cell Acute Lymphoblastic Leukemia

MYD88 Triggered SYK Activation Promotes BCR Cross-Talk, and Identifies SYK As a Novel Therapeutic Target of Mutated MYD88 Signaling

The Role of Cbx Proteins in Human Benign and Malignant Hematopoiesis

NR4A3 Suppresses Lymphomagenesis I n Vitro and In Vivo by Induction of Similar Patterns of Pro-Apoptotic Genes like NR4A1

Genetic Depletion of Fc Gamma Receptor 2b Affects CML Stem Cell Biology

Identification of CAR As a Novel Mediator of Erythroid Differentiation and Migration That Is Specifically Downregulated in Erythropoietic Progenitor Cells in Patients with MDS

Peroxiredoxin 6 (Prdx6) Is Associated with Changes in Autophagy in Myeloid and Non-Myeloid Cells

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression

RUNX1a Enhances Hematopoietic Lineage Commitment From Human Embryonic Stem Cells and Inducible Pluripotent Stem Cells

Apoptosis Repressor with Caspase Recruitment Domain Is Regulated by the cIAP1-NIK Axis and Confers Resistance to SMAC Mimetic Birinapant-Induced Cell Death in AML

Mutant U2AF1(S34F) Expression Alters Hematopoiesis in Mice

Regulation of Fas-mediated Apoptosis in B-Cell Lymphomas by Nucleolin.

Dysregulation of GPR34 in Indolent Lymphomas and Its Function As a Novel Regulator of Cell Growth and Gene Expression

GATA1s Exerts Fetal Stage-Specific Oncogenic Effects in Human Hematopoietic Stem and Progenitor Cells

Impaired Reconstitution Potential of TGFβ-Hypersensitive Human Hematopoietic Stem Cells

A Novel Ubiquitination Pathway Regulates MLL Activity During Hematopoietic Differentiation

SYK Is a Tumor Suppressor In Pre-B Cell Acute Lymphoblastic Leukemia and Not a Therapeutic Target

SMAC-Mimetic BV-6 Sensitizes Therapeutic Agents-Induced Apoptosis In AML Cells

Group A Pak Proteins Are Essential for HSC/P Engraftment.

PAX5/TEL Exhibits a Dominant-Negative Role by Inhibiting the Expression of Genes Involved in BCR Signalling and Suppressing the Binding of Wild Type PAX5 to Its Direct Target Gene CD79A (mb-1) in a human Pre-B ALL Cell Line.

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American Society of Hematology

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American Society of Hematology

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