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Journal Articles

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

Clinical Trials & Observations
Ottavia M. Delmonte, Jenna R. E. Bergerson, Tomoki Kawai, Hye Sun Kuehn, David H. McDermott, Irene Cortese, Michael T. Zimmermann, A. Kerry Dobbs, Marita Bosticardo, Danielle Fink, Shamik Majumdar, Boaz Palterer, Francesca Pala, Nikita R. Dsouza, Marie Pouzolles, Naomi Taylor, Katherine R. Calvo, Stephen R. Daley, Daniel Velez, Anahita Agharahimi, Katherine Myint-Hpu, Lesia K. Dropulic, Jonathan J. Lyons, Steven M. Holland, Alexandra F. Freeman, Rajarshi Ghosh, Morgan B. Similuk, Julie E. Niemela, Jennifer Stoddard, Douglas B. Kuhns, Raul Urrutia, Sergio D. Rosenzweig, Magdalena A. Walkiewicz, Philip M. Murphy, Luigi D. Notarangelo
Journal: Blood
Blood (2021) 138 (12): 1019–1033.
https://doi.org/10.1182/blood.2020008629
Published: 2021
Includes: Supplemental data
Journal Articles

PD-1 Blockade Reinvigorates Bone Marrow CD8 + T Cells from Patients with Multiple Myeloma in the Presence of TGF-β Inhibitors

Minsuk Kwon, MD PhD, Eui-Cheol Shin, MD PhD, Yoon Seok Choi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3241.
https://doi.org/10.1182/blood-2019-128182
Published: 2019
Journal Articles

Rapid Personalized Manufacture (RPM) of Sleeping Beauty System-Generated NY-ESO-1-Specific TCR-T Cells Co-Expressing Membrane-Bound IL-15 Yields Anti-Tumor Responses

Lenka V Hurton, PhD, Tiejuan Mi, Kirsten C Switzer, PhD, Ling Zhang, Cuiping Dai, Misun Kim, Karishma R Bavisi, Matthew J Figliola, Vazquez M Lydia, Sourindra N Maiti, Shihuang Su, Drew C Deniger, PhD, Simon Olivares, Laurence J N Cooper, MD PhD, Harjeet Singh, MSc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3218.
https://doi.org/10.1182/blood-2019-131419
Published: 2019
Journal Articles

FT819: Translation of Off-the-Shelf TCR-Less Trac-1XX CAR-T Cells in Support of First-of-Kind Phase I Clinical Trial

Chiawei Chang, Sjoukje Van Der Stegen, PhD, Mandal Mili, PhD, Raedun Clarke, PhD, Yi-Shin Lai, PhD, Alec Witty, PhD, Pieter Lindenbergh, Bi-Huei Yang, PhD, Mushtaq Husain, PhD, Helena Shaked, PhD, Brian Groff, Laurel Stokely, Ramzey Abujarour, PhD, Tom Lee, PhD, Hui-Yi Chu, PhD, Mochtar Pribadi, PhD, Jason ORourke, PhD, Alma Gutierrez, Isabelle Riviere, PhD, Michel Sadelain, MD PhD, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4434.
https://doi.org/10.1182/blood-2019-130584
Published: 2019
Journal Articles

Myeloid-Derived Suppressor Cells As Potential Contributors to Pregnancy-Associated Lymphoma Progression

Netanel A Horowitz, MD, Noam Bettman, PhD, Ali Abd El Wahed, Tamar Katz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3979.
https://doi.org/10.1182/blood-2019-124292
Published: 2019
Journal Articles

Aberrant SYK Expression As a Potential Therapeutic Target in T/NK Cell Neoplasms

Jing-Ping Zhang, PhD, Qi Gao, MLS, Alexander Chan, MD, Wenbin Xiao, MD PhD, Sary El Daker, PhD, Mikhail Roshal, MD PhD, Ahmet Dogan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3978.
https://doi.org/10.1182/blood-2019-130406
Published: 2019
Journal Articles

Genome-Wide microRNA Expression Profiling in Molecular Subgroups of Peripheral T-Cell Lymphoma Identified Role of Mir-126 in T-Cell Lymphomagenesis

Waseem Lone, PhD, Alyssa Bouska, PhD, Tyler Herek, BS,MS, Catalina Amador, MD, Mallick Saumyaranajn, MD, Yu Jiayu, Tayla Heavican, Stefano A. Pileri, MD PhD, Timothy McKeithan, MD PhD, Wing C. Chan, MD, Javeed Iqbal, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2767.
https://doi.org/10.1182/blood-2019-129327
Published: 2019
Journal Articles

A CXCL10/CXCR3 Driven Thymic Epithelium-Leukemia Cell Crosstalk Augments T Cell Acute Lymphoblastic Leukemia Notch1 Signalling

Ashwini M Patil, MSc, Stefanie Kesper, Vishal Khairnar, PhD, Marco Luciani, Michael Möllmann, Ulrich Dührsen, Prof, MD PhD, Joachim R Göthert, PD, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2537.
https://doi.org/10.1182/blood-2019-125331
Published: 2019
Journal Articles

LIM Domain Protein 1 (Ldb1) Is Required for Lmo2 Oncogene-Induced Thymocyte Self-Renewal and T-Cell Leukemia in a Mouse Model of Human T-ALL

Liqi Li, PhD, Apratim Mitra, Bin Zhao, Seeyoung Choi, Jan Lee, Daniel Stamos, Claude Warzecha, Karl Pfeifer, Joyce Hardwick, Bryan Venters, Paul Love, Utpal Dave, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2538.
https://doi.org/10.1182/blood-2019-127534
Published: 2019
Journal Articles

System-Level Disease-Driven Immune Signatures in Patients with Diffuse Large B-Cell Lymphoma Associated with Poor Survival

Astrid Tschan-Plessl, MD, Eivind Heggernes Ask, Thea Johanne Gjerdingen, Michelle Saetersmoen, Hanna Julie Hoel, Merete Thune Wiiger, Msc, Johanna Olweus, Björn E Wahlin, MD PhD, Amir Horowitz, PhD, Todd A Fehniger, MD PhD, Harald Holte, MD PhD, Arne Kolstad, MD PhD, Karl-Johan Malmberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2897.
https://doi.org/10.1182/blood-2019-131359
Published: 2019
Journal Articles

Towards Understanding & Uncovering New Key Players in T-Cell Development upon Aging

Hanane Boukarabila, PhD, Kalpana Nattamai, Medhanie Assmelash Mulaw, PhD, Hartmut Geiger, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2482.
https://doi.org/10.1182/blood-2019-127294
Published: 2019
Journal Articles

Multidimensional Single Cell Analysis Shows Increased T/NK Cell Subsets in Both Blood and Bone Marrow of Iberdomide (CC-220) Treated Relapsed/Refractory Multiple Myeloma Patients

Michael Amatangelo, Oliver Van Oekelen, MD MSc, Adeeb H Rahman, PhD, Alessandro Lagana, PhD, Sarah Gooding, FRCPath,MRCP,MBBChir, Hervé Avet-Loiseau, MD PhD, Udo Oppermann, PhD, William E Pierceall, PhD, Anjan Thakurta, Samir Parekh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1775.
https://doi.org/10.1182/blood-2019-126146
Published: 2019
Journal Articles

Imbalance in T Cell Subsets Triggers the Autoimmune Toxicity of PI3K Inhibitors in CLL

Deepti Gadi, PhD, Siddha Kasar, PhD, Alec Griffith, BS, Pui Yan Chiu, Svitlana Tyekucheva, PhD, Vanessa Rai, BS, Alexander R. Vartanov, MD, Stacey M. Fernandes, BS, Yang Pan, PhD, James A Lederer, PhD, Barbara Sherry, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1745.
https://doi.org/10.1182/blood-2019-122961
Published: 2019
Journal Articles

β2- Adrenergic Signaling Regulates Graft Versus Host Disease after Allogenic Transplantation While Preserving Graft Versus Leukemia Effect

Hemn Mohammadpour, PhD DVM, Joseph L. Sarow, BS, George L. Chen, MD, Cameron R. MacDonald, BS, Umesh Sharma, MD, Megan M. Herr, PhD, Theresa E. Hahn, PhD, Elizabeth A. Repasky, PhD, Philip L. McCarthy, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1915.
https://doi.org/10.1182/blood-2019-123139
Published: 2019
Journal Articles

Immunophenotyping and Function of Peripheral Blood Mononuclear Cells in Patients Undergoing Unrelated Allogeneic Transplantation with Post-Transplantation Cyclophosphamide in Combination with ATG Anti-Graft Versus Host Disease Prophylaxis

Katia Beider, Valeria Voevoda, Noga Shem-Tov, MD, Ronit Yerushalmi, MD, Ivetta Danilesko, MD, Ania Hava Grushchenko-Polaq, Olivia Devillers, Idit Wolf, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Arnon Nagler, MD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1989.
https://doi.org/10.1182/blood-2019-129619
Published: 2019
Journal Articles

Guided Polarization of iPSC-Derived CD4SP Helper T Cells By CRISPR/Cas9-Based Genome-Editing

Hisashi Yano, MD, Tokuyuki Shinohara, PhD, Keiko Koga, PhD, Shoichi Iriguchi, PhD, Yasuyuki Miyake, Xuewei Song, Megumi Tada, Yoshiaki Kassai, PhD, Hitoshi Kiyoi, MD PhD, Shin Kaneko, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1937.
https://doi.org/10.1182/blood-2019-122193
Published: 2019
Journal Articles

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

Jose Rodriguez Cortes, PhD, Anisha R. Cooke, Aidan Quinn, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD, Teresa Palomero, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1482.
https://doi.org/10.1182/blood-2019-129438
Published: 2019
Journal Articles

Pharmacologic Inhibition of SUMO-Activating Enzyme (SAE) with TAK-981 Augments Interferon Signaling and Regulates T Cell Differentiation in Ex Vivo studies of Chronic Lymphocytic Leukemia (CLL)

Vi Lam, Scott R Best, BS, Nur Bruss, BS, Tingting Liu, Taylor Hashiguchi Rowland, BS, Dennis Huszar, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1760.
https://doi.org/10.1182/blood-2019-127539
Published: 2019
Journal Articles

Stim1 Deletion Synthetically Rescues Ezh2-Null Effector T Cells and Alloimmunity

Ying Wang, PhD, Shan He, PhD, Yongnian Liu, Robert Hooper, PhD, Hongshuang Yu, Yuanyuan Tian, Hongxing Sun, PhD, Ran Reshef, MD MSc, Elizabeth O. Hexner, MD MS, Jonathan Soboloff, Yi Zhang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4533.
https://doi.org/10.1182/blood-2018-99-118720
Published: 2018
Journal Articles

Pluripotent Cell-Derived Off-the-Shelf TCR-Less CAR-Targeted Cytotoxic T Cell Therapeutic for the Allogeneic Treatment of B Cell Malignancies

Raedun Clarke, PhD, Sjoukje Van Der Stegen, PhD, Chia-Wei Chang, PhD, Mushtaq Husain, PhD, Yi-Shin Lai, PhD, Eigen Peralta, PhD, Laurel Stokely, Ramzey Abujarour, PhD, Jason Dinella, PhD, Tom Lee, PhD, Mochtar Pribadi, PhD, Helen Chu, PhD, Chris Truong, Mohsen Sabouri-Ghomi, PhD, Miguel Meza, BS, Judith Feucht, MD, Justin Eyquem, PhD, Jorge Mansilla-Soto, PhD, Isabelle Riviere, PhD, Michel Sadelain, MD PhD, Bahram Valamehr, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4546.
https://doi.org/10.1182/blood-2018-99-116843
Published: 2018