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David Segal
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Journal Articles

The Role of BAX/BAK-Mediated Apoptosis for the Cytotoxic Action of Anti-Myeloma Agents

Yuan Yao, Jia-Nan Gong, PhD, David Segal, PhD, Chris D Riffkin, Mark F van Delft, PhD, Andrew W. Roberts, MBBS, PhD, David CS Huang, MBBS, MRCP, PhD
Journal: Blood
Blood (2016) 128 (22): 5706.
https://doi.org/10.1182/blood.V128.22.5706.5706
Published: 2016
Journal Articles

Targeting the Pro-Survival BCL2 Proteins with BH3 Mimetic Compounds for Treating Multiple Myeloma

Jia-Nan Gong, PhD, Tiffany Khong, PhD, David Segal, PhD, Yuan Yao, Mark F van Delft, PhD, Andrew Spencer, Andrew W Roberts, MBBS, PhD, David CS Huang, MBBS, MRCP, PhD
Journal: Blood
Blood (2016) 128 (22): 3293.
https://doi.org/10.1182/blood.V128.22.3293.3293
Published: 2016
Journal Articles

Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1

Jia-Nan Gong, Tiffany Khong, David Segal, Yuan Yao, Chris D. Riffkin, Jean-Marc Garnier, Seong Lin Khaw, Guillaume Lessene, Andrew Spencer, Marco J. Herold, Andrew W. Roberts, David C. S. Huang
Journal: Blood
Blood (2016) 128 (14): 1834–1844.
https://doi.org/10.1182/blood-2016-03-704908
Published: 2016
Includes: Supplemental data
Journal Articles

The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism

Mary Ann Anderson, Jing Deng, John F. Seymour, Constantine Tam, Su Young Kim, Joshua Fein, Lijian Yu, Jennifer R. Brown, David Westerman, Eric G. Si, Ian J. Majewski, David Segal, Sari L. Heitner Enschede, David C. S. Huang, Matthew S. Davids, Anthony Letai, Andrew W. Roberts
Journal: Blood
Blood (2016) 127 (25): 3215–3224.
https://doi.org/10.1182/blood-2016-01-688796
Published: 2016
Includes: Supplemental data
Journal Articles

E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis

Kamil Wolyniec, Jake Shortt, Elisa de Stanchina, Yaara Levav-Cohen, Osnat Alsheich-Bartok, Igal Louria-Hayon, Vincent Corneille, Beena Kumar, Simone J. Woods, Stephen Opat, Ricky W. Johnstone, Clare L. Scott, David Segal, Pier Paolo Pandolfi, Stephen Fox, Andreas Strasser, Yong-Hui Jiang, Scott W. Lowe, Sue Haupt, Ygal Haupt
Journal: Blood
Blood (2012) 120 (4): 822–832.
https://doi.org/10.1182/blood-2011-10-387647
Published: 2012
Includes: Supplemental data