Page 1 | Search Results | Blood | American Society of Hematology

1-18 of 18

Sort by

Sort Order Select

Journal Articles

Pipeline for Discovering Neoepitopes Generated By Alternative Splicing in B-ALL

Sisi Zheng, MD, Ammar S. Naqvi, PhD, Elisabeth Bolton-Gillespie, Mukta Asnani, Katharina Hayer, Yoseph Barash, PhD, Andrei Thomas-Tikhonenko, PhD

Blood (2019) 134 (Supplement_1): 1342.

https://doi.org/10.1182/blood-2019-131277

Published: 2019

Journal Articles

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Leukemia Cells

Katherine Sullivan, Elisabeth Bolton-Gillespie, Yashodhara Dasgupta, Samantha Langer, Micheal Siciliano, Margaret Nieborowska-Skorska, Huaqing Zhao, Peter Valent, Tomasz Skorski

Blood (2017) 130 (Supplement 1): 4623.

https://doi.org/10.1182/blood.V130.Suppl_1.4623.4623

Published: 2017

Journal Articles

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

Yashodhara Dasgupta, Mateusz Koptyra, Grazyna Hoser, Kanchan Kantekure, Darshan Roy, Barbara Gornicka, Margaret Nieborowska-Skorska, Elisabeth Bolton-Gillespie, Sabine Cerny-Reiterer, Markus Müschen, Peter Valent, Mariusz A. Wasik, Christine Richardson, Oliver Hantschel, Heiko van der Kuip, Tomasz Stoklosa, Tomasz Skorski

Blood (2016) 127 (17): 2131–2143.

https://doi.org/10.1182/blood-2015-11-681171

Published: 2016

Includes: Supplemental data

Journal Articles

Targeting of Quiescent and Proliferating CML Stem Cells By DNA Repair Inhibitors

Katherine Sullivan, Elisabeth Bolton-Gillespie, Margaret Nieborowska-Skorska, Sabine Cerny-Reiterer, DVM, Peter Valent, MD, Markus Muschen, MDPhD, Richard Pomerantz, Alexander Mazin, Tomasz Skorski

Blood (2015) 126 (23): 50.

https://doi.org/10.1182/blood.V126.23.50.50

Published: 2015

Journal Articles

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD PhD, Katherine Sullivan, Paulina Podszywalow-Bartnicka, Grazyna Hoser, PhD, Elisabeth Bolton-Gillespie, Kimberly Cramer-Morales, Artur Slupianek, PhD, Chun Zhou, PhD, Sabine Cerny-Reiterer, DVM, Tomasz Stoklosa, MD PhD, Stephen M. Sykes, PhD, Peter Valent, MD, Curt I. Civin, MD, Markus Muschen, MD PhD, Mark D. Minden, MD PhD, Kolja Eppert, PhD, Tomasz Skorski, MD PhD

Blood (2014) 124 (21): 480.

https://doi.org/10.1182/blood.V124.21.480.480

Published: 2014

Journal Articles

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

Yashodhara Dasgupta, Mateusz Koptyra, PhD, Margaret Nieborowska-Skorska, MD, PhD, Elisabeth Bolton Gillespie, PhD, Tomasz Stoklosa, MD, PhD, Grazyna Hoser, PhD, Mariusz Wasik, MD, Markus Muschen, Christine Richardson, PhD, Tomasz Skorski, MD, PhD

Blood (2013) 122 (21): 1466.

https://doi.org/10.1182/blood.V122.21.1466.1466

Published: 2013

Journal Articles

Oncogene-Induced DNA Repair Defects Promote PARP1-Mediated “Dual Synthetic Lethality” To Eradicate Quiescent and Proliferating Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD, PhD, Artur Slupianek, PhD, Grazyna Hoser, PhD, Elisabeth Bolton-Gillespie, PhD, Alexei Tulin, Sabine Cerny-Reiterer, D.V.M, Peter Valent, Markus Muschen, Stephen M. Sykes, PhD, Tomasz Skorski, MD, PhD

Blood (2013) 122 (21): 810.

https://doi.org/10.1182/blood.V122.21.810.810

Published: 2013

Journal Articles

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

Elisabeth Bolton-Gillespie, Mirle Schemionek, Hans-Ulrich Klein, Sylwia Flis, Grazyna Hoser, Thoralf Lange, Margaret Nieborowska-Skorska, Jacqueline Maier, Linda Kerstiens, Mateusz Koptyra, Martin C. Müller, Hardik Modi, Tomasz Stoklosa, Ilona Seferynska, Ravi Bhatia, Tessa L. Holyoake, Steffen Koschmieder, Tomasz Skorski

Blood (2013) 121 (20): 4175–4183.

https://doi.org/10.1182/blood-2012-11-466938

Published: 2013

Includes: Supplemental data

Journal Articles

Genomic Instability in CML-CP originates From the Most Primitive Imatinib-Refractory Leukemia Stem Cells

Elisabeth Bolton, Mirle Schemionek, PhD, Hans-Urlich Klein, Grazyna Hoser, PhD, Sylwia Flis, Thoralf Lange, Linda Kerstiens, Margaret Nieborowska-Skorska, MD, PhD, Martin C. Müller, MD, Hardik Modi, Ravi Bhatia, MD, Steffen Koschmieder, MD, Tomasz Skorski, MD, PhD

Blood (2012) 120 (21): 909.

https://doi.org/10.1182/blood.V120.21.909.909

Published: 2012

Journal Articles

Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

Blood (2012) 119 (18): 4253–4263.

https://doi.org/10.1182/blood-2011-10-385658

Published: 2012

Includes: Supplemental data

Journal Articles

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

Blood (2011) 118 (21): 2736.

https://doi.org/10.1182/blood.V118.21.2736.2736

Published: 2011

Journal Articles

Genomic Instability Originates From Leukemia Stem Cells in a Mouse Model of CML-CP

Elisabeth Bolton, Mirle Schemionek, PhD, Hans-Ulrich Klein, Linda Kerstiens, Steffen Koschmieder, MD, Tomasz Skorski, MD, PhD

Blood (2011) 118 (21): 445.

https://doi.org/10.1182/blood.V118.21.445.445

Published: 2011

Journal Articles

Targeting DNA Repair Gene, RAD52, Induces Exhaustion of the Proliferating CML-CP Leukemia Stem Cells Carrying Oxidative DNA Damage

Kimberly Cramer, Elisabeth Bolton, Margaret Nieborowska-Skorska, MD, PhD, Sylwia Flis, Tomasz Skorski, MD, PhD

Blood (2011) 118 (21): 447.

https://doi.org/10.1182/blood.V118.21.447.447

Published: 2011

Journal Articles

CML-CP Mouse Model of Genomic Instability.

Elisabeth Bolton, Linda Kamp, Hardik Modi, Ravi Bhatia, MD, Steffen Koschmieder, MD, Tomasz Skorski, MD, PhD

Blood (2010) 116 (21): 1210.

https://doi.org/10.1182/blood.V116.21.1210.1210

Published: 2010

Journal Articles

Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.

Piotr Kopinski, Margaret Nieborowska-Skorska, MD, PhD, Grazyna Hoser, PhD, Danielle Ngaba, Regina Ray, Mateusz Koptyra, PhD, Elisabeth Bolton, Ilona Seferynska, MD, PhD, Tomasz Stoklosa, MD, PhD, Artur Slupianek, PhD, Mamatha R. Reddy, Martin Sattler, PhD, Tomasz Skorski, MD, PhD

Blood (2010) 116 (21): 1211.

https://doi.org/10.1182/blood.V116.21.1211.1211

Published: 2010

Journal Articles

ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial Respiratory Chain Complex III.

Margaret Nieborowska-Skorska, Ph.D., Mateusz Koptyra, PhD, Elisabeth Bolton, Regina Ray, Danielle Ngaba, Grazyna Hoser, PhD, Tomasz Stoklosa, M.D., Ph.D., Artur Slupianek, PhD, Piotr Kopinski, Tomasz Skorski, MD, PhD

Blood (2009) 114 (22): 3268.

https://doi.org/10.1182/blood.V114.22.3268.3268

Published: 2009

Journal Articles

Mechanisms Generating free Radicals in CML Stem/Progenitor Cell Populations Causing DNA Damage and Genomic Instability

Margaret Nieborowska-Skorska, MD, PhD, Mateusz Koptyra, PhD, Grazyna Hoser, PhD, Regina Ray, Danielle Ngaba, Elisabeth Bolton, Tomasz Skorski, MD, PhD

Blood (2008) 112 (11): 192.

https://doi.org/10.1182/blood.V112.11.192.192

Published: 2008

Journal Articles

Phosphatidylinositol 3-Kinase p85 Subunit-Dependent Interaction with BCR/ABL: Molecular Mechanism and Biological Consequences.

Shuyue Ren, MD, PhD, Elisabeth Bolton, BS, Tomasz Skorski, MD, PhD

Blood (2004) 104 (11): 2953.

https://doi.org/10.1182/blood.V104.11.2953.2953

Published: 2004

NARROW

Pipeline for Discovering Neoepitopes Generated By Alternative Splicing in B-ALL

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Leukemia Cells

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

Targeting of Quiescent and Proliferating CML Stem Cells By DNA Repair Inhibitors

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Normal ABL1 Is a Tumor Suppressor and Therapeutic Target In BCR-ABL1–positive Leukemias

Oncogene-Induced DNA Repair Defects Promote PARP1-Mediated “Dual Synthetic Lethality” To Eradicate Quiescent and Proliferating Leukemia Stem and Progenitor Cells

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

Genomic Instability in CML-CP originates From the Most Primitive Imatinib-Refractory Leukemia Stem Cells

Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

Genomic Instability Originates From Leukemia Stem Cells in a Mouse Model of CML-CP

Targeting DNA Repair Gene, RAD52, Induces Exhaustion of the Proliferating CML-CP Leukemia Stem Cells Carrying Oxidative DNA Damage

CML-CP Mouse Model of Genomic Instability.

Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.

ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial Respiratory Chain Complex III.

Mechanisms Generating free Radicals in CML Stem/Progenitor Cell Populations Causing DNA Damage and Genomic Instability

Phosphatidylinositol 3-Kinase p85 Subunit-Dependent Interaction with BCR/ABL: Molecular Mechanism and Biological Consequences.

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only